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List of works by Bruno Lemaitre

A Drosophila pattern recognition receptor contains a peptidoglycan docking groove and unusual L,D-carboxypeptidase activity

scientific article

A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity

scientific article published on January 2006

A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway

scientific article

A genetic framework controlling the differentiation of intestinal stem cells during regeneration in Drosophila.

scientific article published on 29 June 2017

A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF.

scientific article

A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK

scientific article

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense

scientific article

A secondary metabolite acting as a signalling molecule controls Pseudomonas entomophila virulence

scientific article

A secreted factor NimrodB4 promotes the elimination of apoptotic corpses by phagocytes in Drosophila

scientific article published on 09 August 2021

A serpin that regulates immune melanization in the respiratory system of Drosophila

scientific article

A single gene that promotes interaction of a phytopathogenic bacterium with its insect vector, Drosophila melanogaster

scientific article

A single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway

scholarly article

A ubiquitin-proteasome pathway represses the Drosophila immune deficiency signaling cascade

scientific article published in October 2002

Accumulation of differentiating intestinal stem cell progenies drives tumorigenesis

scientific article

An immune-responsive Serpin regulates the melanization cascade in Drosophila

scientific article published in October 2002

Anatomy and Physiology of the Digestive Tract of

scientific article published on 01 October 2018

Animal models for host-pathogen interactions

scientific article published on 5 June 2008

Antimicrobial peptide defense in Drosophila

scientific article published on November 1997

Association of hemolytic activity of Pseudomonas entomophila, a versatile soil bacterium, with cyclic lipopeptide production

scientific article

Autocrine and paracrine unpaired signaling regulate intestinal stem cell maintenance and division

scientific article

Bacterial strategies to overcome insect defences

scientific article published on 10 March 2008

Blind killing of both male and female Drosophila embryos by a natural variant of the endosymbiotic bacterium Spiroplasma poulsonii

scientific article published on 23 January 2020

Cell Division by Longitudinal Scission in the Insect Endosymbiont Spiroplasma poulsonii

scientific article

Cell-Specific Imd-NF-κB Responses Enable Simultaneous Antibacterial Immunity and Intestinal Epithelial Cell Shedding upon Bacterial Infection

article

Chemometric Analysis of Bacterial Peptidoglycan Reveals Atypical Modifications That Empower the Cell Wall against Predatory Enzymes and Fly Innate Immunity

scientific article published on 23 June 2016

Common and unique strategies of male killing evolved in two distinct symbionts

scientific article published in 2018

Comparative RNA-Seq analyses of Drosophila plasmatocytes reveal gene specific signatures in response to clean injury and septic injury

scientific article published on 29 June 2020

Complete genome sequence of the entomopathogenic and metabolically versatile soil bacterium Pseudomonas entomophila

scientific article

Connecting the obesity and the narcissism epidemics

scientific article published on 12 August 2016

Constitutive expression of a single antimicrobial peptide can restore wild-type resistance to infection in immunodeficient Drosophila mutants

scientific article

Correction: Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach

scientific article published on 28 May 2019

Crystallization and preliminary X-ray analysis of monalysin, a novel β-pore-forming toxin from the entomopathogen Pseudomonas entomophila

scientific article published on 27 July 2013

Determination of the structure of the O-antigen and the lipid A from the entomopathogenic bacterium Pseudomonas entomophila lipopolysaccharide along with its immunological properties

scientific article

Different flavors of Toll guide olfaction

scientific article published on 3 July 2015

Directed expression of the HIV-1 accessory protein Vpu in Drosophila fat-body cells inhibits Toll-dependent immune responses

scientific article

Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection

scientific article

Drosophila P element: transposition, regulation and evolution

scientific article published on January 1994

Drosophila Serpin-28D regulates hemolymph phenoloxidase activity and adult pigmentation

scientific article

Drosophila host defense after oral infection by an entomopathogenic Pseudomonas species

scientific article

Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms

scientific article published on December 1997

Drosophila immunity: a large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation

scientific article published in April 2006

Drosophila immunity: analysis of PGRP-SB1 expression, enzymatic activity and function

scientific article

Drosophila immunity: analysis of larval hemocytes by P-element-mediated enhancer trap

scientific article published on October 1997

Drosophila immunity: methods for monitoring the activity of Toll and Imd signaling pathways

scientific article published in January 2008

Drosophila immunity: two paths to NF-kappaB.

scientific article published in May 2001

Drosophila innate immunity: regional and functional specialization of prophenoloxidases

scientific article published on October 2015

Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation

scientific article published in February 2009

Drosophila: a polyvalent model to decipher host-pathogen interactions

scientific article published on May 2004

Dual proteomics of Drosophila melanogaster hemolymph infected with the heritable endosymbiont Spiroplasma poulsonii

scientific article published on 29 April 2021

Ecology-relevant bacteria drive the evolution of host antimicrobial peptides in <i>Drosophila</i>

scientific article published on 20 July 2023

Erwinia carotovora Evf antagonizes the elimination of bacteria in the gut of Drosophila larvae

article by Carlos Acosta Muniz et al published January 2007 in Cellular Microbiology

Evolution of longevity improves immunity in

scientific article published on 12 November 2018

Expression of antimicrobial peptide genes after infection by parasitoid wasps in Drosophila

scientific article published in May 1996

From Embryo to Adult: Hematopoiesis along the Drosophila Life Cycle.

scientific article published on May 2015

Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila.

scientific article published on February 1995

Functional analysis of PGRP-LA in Drosophila immunity.

scientific article

Functional analysis of RIP toxins from the Drosophila endosymbiont Spiroplasma poulsonii

scientific article published on 20 February 2019

Genes that fight infection: what the Drosophila genome says about animal immunity

scientific article

Genetic ablation of Drosophila phagocytes reveals their contribution to both development and resistance to bacterial infection.

scientific article published in April 2009

Genetic evidence for a protective role of the peritrophic matrix against intestinal bacterial infection in Drosophila melanogaster

scientific article

Genetic, molecular and physiological basis of variation in Drosophila gut immunocompetence

scientific article published on 27 July 2015

Genome sequence of the Drosophila melanogaster male-killing Spiroplasma strain MSRO endosymbiont

scientific article

Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays ⬇️

scientific article

Gram-negative bacteria-binding protein, a pattern recognition receptor for lipopolysaccharide and beta-1,3-glucan that mediates the signaling for the induction of innate immune genes in Drosophila melanogaster cells

scientific article

Gut homeostasis in a microbial world: insights from Drosophila melanogaster

scientific article

Gut physiology mediates a trade-off between adaptation to malnutrition and susceptibility to food-borne pathogens

scientific article

Gut-associated microbes of Drosophila melanogaster

scientific article

How Drosophila combats microbial infection: a model to study innate immunity and host-pathogen interactions

scientific article

Immunology. Pathogen surveillance--the flies have it.

scientific article published in April 2002

In Vitro Culture of the Insect Endosymbiont Spiroplasma poulsonii Highlights Bacterial Genes Involved in Host-Symbiont Interaction.

scientific article published on 20 March 2018

In vivo RNA interference analysis reveals an unexpected role for GNBP1 in the defense against Gram-positive bacterial infection in Drosophila adults

scientific article published on 13 January 2004

In vivo regulation of the IkappaB homologue cactus during the immune response of Drosophila

scientific article published in April 1998

Inducible expression of double-stranded RNA reveals a role for dFADD in the regulation of the antibacterial response in Drosophila adults

scientific article published in June 2002

Infection Dynamics and Immune Response in a Newly Described Drosophila-Trypanosomatid Association.

scientific article

Infection-induced host translational blockage inhibits immune responses and epithelial renewal in the Drosophila gut.

scientific article published in July 2012

Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway

scientific article

Insect endosymbiont proliferation is limited by lipid availability.

scientific article

Insect immunity: from pattern recognition to symbiont-mediated host defense

scientific article published in August 2009

Insect immunity: the diptericin promoter contains multiple functional regulatory sequences homologous to mammalian acute-phase response elements.

scientific article published on December 1993

Insect immunity: the post-genomic era.

scientific article published in July 2006

Insect-microbe interactions: the good, the bad and the others

scientific article published on 7 June 2012

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

scientific article published on October 2009

Long-range activation of systemic immunity through peptidoglycan diffusion in Drosophila

scientific article

Male-killing symbiont damages host's dosage-compensated sex chromosome to induce embryonic apoptosis

scientific article published on 21 September 2016

Male-killing toxin in a bacterial symbiont of Drosophila

scientific article published in Nature

Maternal inheritance of P cytotype in Drosophila melanogaster: a "pre-P cytotype" is strictly extra-chromosomally transmitted

scientific article published in October 1993

Maternal repression of the P element promoter in the germline of Drosophila melanogaster: a model for the P cytotype.

scientific article

Mercury is a direct and potent γ-secretase inhibitor affecting Notch processing and development in Drosophila

scientific article published on 17 March 2011

Methods to study Drosophila immunity

scientific article published on 12 March 2014

Microbiota-Derived Lactate Activates Production of Reactive Oxygen Species by the Intestinal NADPH Oxidase Nox and Shortens Drosophila Lifespan

scientific article published on 13 November 2018

Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology

scientific article

Monalysin, a novel ß-pore-forming toxin from the Drosophila pathogen Pseudomonas entomophila, contributes to host intestinal damage and lethality

scientific article

Morphological and Molecular Characterization of Adult Midgut Compartmentalization in Drosophila

Morphological and molecular characterization of adult midgut compartmentalization in Drosophila

scientific article published on 2 May 2013

Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses

scientific article

Negative regulation by amidase PGRPs shapes the Drosophila antibacterial response and protects the fly from innocuous infection

scientific article published in November 2011

New insights on Drosophila antimicrobial peptide function in host defense and beyond

scientific article published on 11 December 2019

P regulatory products repress in vivo the P promoter activity in P-lacZ fusion genes

scientific article published on May 1991

PGRP-SD, an Extracellular Pattern-Recognition Receptor, Enhances Peptidoglycan-Mediated Activation of the Drosophila Imd Pathway

scientific article published on November 2016

PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling

scientific article published on August 2008

Peptidoglycan molecular requirements allowing detection by the Drosophila immune deficiency pathway

scientific article

Phagocytosis in Drosophila: From molecules and cellular machinery to physiology

scientific article published on 03 April 2019

Physiological Adaptations to Sugar Intake: New Paradigms from Drosophila melanogaster

scientific article published on 3 December 2016

Pillars article: the dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 1996. 86: 973-983

scientific article published on June 1, 2012

Prevalence of local immune response against oral infection in a Drosophila/Pseudomonas infection model

scientific article

Prophenoloxidase activation is required for survival to microbial infections in Drosophila

scientific article

Protection from within

scientific article published on 12 January 2017

Proteolytic cascade for the activation of the insect toll pathway induced by the fungal cell wall component

scientific article published on 27 May 2009

Rapid molecular evolution of Spiroplasma symbionts of Drosophila

scientific article published on 16 February 2021

Recognition and response to microbial infection in Drosophila

article

Remote Control of Intestinal Stem Cell Activity by Haemocytes in Drosophila

scientific article

Science, narcissism and the quest for visibility

scientific article published on 10 February 2017

Sensing Gram-negative bacteria: a phylogenetic perspective

scientific article

Sensing microbes by diverse hosts. Workshop on pattern recognition proteins and receptors

scientific article published on 19 September 2003

Spiroplasma and host immunity: activation of humoral immune responses increases endosymbiont load and susceptibility to certain Gram-negative bacterial pathogens in Drosophila melanogaster ⬇️

scientific article published on July 11, 2011

Steroid-dependent switch of OvoL/Shavenbaby controls self-renewal versus differentiation of intestinal stem cells

scientific article published on 29 December 2020

Stop press: genes that fight infections: what the drosophila genome says about animal immunity

article

Structure and metabolism of peptidoglycan and molecular requirements allowing its detection by the Drosophila innate immune system

scientific article

Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach

Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach

scientific article published on 26 February 2019

Taxonomic characterisation of Pseudomonas strain L48 and formal proposal of Pseudomonas entomophila sp. nov.

scientific article

The Black cells phenotype is caused by a point mutation in the Drosophila pro-phenoloxidase 1 gene that triggers melanization and hematopoietic defects

scientific article published on 24 December 2014

The Drosophila MAPK p38c regulates oxidative stress and lipid homeostasis in the intestine

scientific article (publication date: September 2014)

The Drosophila amidase PGRP-LB modulates the immune response to bacterial infection.

scientific article published in April 2006

The Drosophila caspase Dredd is required to resist gram-negative bacterial infection

scientific article

The Drosophila immune system detects bacteria through specific peptidoglycan recognition

scientific article published in May 2003

The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection

scientific article published on 7 August 2006

The MAPKKK Mekk1 regulates the expression of Turandot stress genes in response to septic injury in Drosophila.

scientific article published in April 2006

The Nimrod transmembrane receptor Eater is required for hemocyte attachment to the sessile compartment in Drosophila melanogaster

scientific article

The Role of Lipid Competition for Endosymbiont-Mediated Protection against Parasitoid Wasps in Drosophila

scientific article published on 12 July 2016

The Toll and Imd pathways are the major regulators of the immune response in Drosophila

scientific article

The Toll immune-regulated Drosophila protein Fondue is involved in hemolymph clotting and puparium formation

scientific article published on 9 May 2006

The adipokine NimrodB5 regulates peripheral hematopoiesis in Drosophila

scientific article published on 03 February 2020

The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in

scientific article published on 30 July 2019

The digestive tract of Drosophila melanogaster

scientific article published on January 2013

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

scientific article

The dual oxidase gene BdDuox regulates the intestinal bacterial community homeostasis of Bactrocera dorsalis

scientific article published on 13 November 2015

The gram-negative sensing receptor PGRP-LC contributes to grooming induction in Drosophila

scientific article published on 9 November 2017

The mosquito genome: the post-genomic era opens

scientific article published in October 2002

The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response

scientific article

The regulatory isoform rPGRP-LC induces immune resolution via endosomal degradation of receptors

scientific article published on 22 August 2016

The road to Toll

scientific article published in July 2004

The wall-less bacterium <i>Spiroplasma poulsonii</i> builds a polymeric cytoskeleton composed of interacting MreB isoforms

scientific article published on 14 November 2021

Thioester-containing proteins regulate the Toll pathway and play a role in Drosophila defence against microbial pathogens and parasitoid wasps

scientific article

Tissue- and ligand-specific sensing of gram-negative infection in drosophila by PGRP-LC isoforms and PGRP-LE.

scientific article published on 6 July 2012

Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia

scientific article published in November 2000

Toll-like receptors--taking an evolutionary approach

scientific article published on March 2008

Transforming Growth Factor β/Activin signaling in neurons increases susceptibility to starvation

scientific article published on 30 October 2017

Transforming growth factor β/activin signaling functions as a sugar-sensing feedback loop to regulate digestive enzyme expression

scientific article published on 2 October 2014

Translation inhibition and metabolic stress pathways in the host response to bacterial pathogens

scientific article published on 13 May 2013

Two Nimrod receptors, NimC1 and Eater, synergistically contribute to bacterial phagocytosis in Drosophila melanogaster

scientific article published on 13 May 2019

Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin

scientific article published in May 1998

Two proteases defining a melanization cascade in the immune system of Drosophila

scientific article published on 21 July 2006

Vertical transmission of a Drosophila endosymbiont via cooption of the yolk transport and internalization machinery

scientific article published on 5 March 2013

X-ray and Cryo-electron Microscopy Structures of Monalysin Pore-forming Toxin Reveal Multimerization of the Pro-form

scientific article

dRYBP contributes to the negative regulation of the Drosophila Imd pathway

scientific article

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