Search filters

List of works by Rejko Krüger

14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta.

scientific article published in December 2002

A comprehensive genetic study of the proteasomal subunit S6 ATPase in German Parkinson's disease patients.

scientific article

A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease

scientific article

A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants

scientific article

A novel heterozygous OPA3 mutation located in the mitochondrial target sequence results in altered steady-state levels and fragmented mitochondrial network

scientific article published on 17 October 2013

A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease

scientific article published on 01 September 2020

Acute parkinsonism with corresponding lesions in the basal ganglia after heroin abuse

scientific article published in February 2007

Advanced stages of PD: interventional therapies and related patient-centered care

scientific article published on 03 July 2015

Aiming for Study Comparability in Parkinson's Disease: Proposal for a Modular Set of Biomarker Assessments to be Used in Longitudinal Studies

scientific article

Alpha-synuclein gene variants may predict neurostimulation outcome

scientific article published on 16 February 2016

Alpha-synuclein repeat variants and survival in Parkinson's disease

scientific article

Anodal tDCS modulates cortical activity and synchronization in Parkinson's disease depending on motor processing

scholarly article by Anna Schoellmann et al published 23 January 2019 in NeuroImage: Clinical

Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study ⬇️

scientific article published on 30 August 2011

Balance is the challenge – The impact of mitochondrial dynamics in Parkinson’s disease ⬇️

scientific article published on November 1, 2010

Behavioural outcomes of subthalamic stimulation and medical therapy versus medical therapy alone for Parkinson's disease with early motor complications (EARLYSTIM trial): secondary analysis of an open-label randomised trial

scientific article published in March 2018

Central oscillators in a patient with neuropathic tremor: evidence from intraoperative local field potential recordings

scientific article published on 13 October 2010

Classification of advanced stages of Parkinson's disease: translation into stratified treatments

scientific article published on 24 March 2017

Collaborative Analysis of α-Synuclein Gene Promoter Variability and Parkinson Disease

scientific article published in The Journal of the American Medical Association

Combined STN/SNr-DBS for the treatment of refractory gait disturbances in Parkinson's disease: study protocol for a randomized controlled trial

scientific article

Combined stimulation of the substantia nigra pars reticulata and the subthalamic nucleus is effective in hypokinetic gait disturbance in Parkinson's disease

scientific article published on 02 February 2011

Complex hyperkinetic movement disorders associated with POLG mutations.

scientific article

Converging environmental and genetic pathways in the pathogenesis of Parkinson's disease ⬇️

scientific article published on April 21, 2011

Cortical correlates of susceptibility to upper limb freezing in Parkinson's disease

scientific article

De novo mutations in hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS).

scientific article published on 6 November 2013

Deep-brain-stimulation does not impair deglutition in Parkinson's disease

scientific article published on 16 May 2012

Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis

scientific article published on 2 September 2010

Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease

scientific article

EIF4G1 is neither a strong nor a common risk factor for Parkinson's disease: evidence from large European cohorts

scientific article

Effects of Subthalamic and Nigral Stimulation on Gait Kinematics in Parkinson's Disease

scientific article published on 17 October 2017

Effects of subthalamic nucleus stimulation on emotional prosody comprehension in Parkinson's disease

scientific article

Effects of transcranial direct current stimulation (tDCS) on executive functions: influence of COMT Val/Met polymorphism

scientific article

Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study

scientific article

First appraisal of brain pathology owing to A30P mutant alpha-synuclein

scientific article published in May 2010

From genome-wide association studies to next-generation sequencing: lessons from the past and planning for the future

scientific article

Functional relevance of ceruloplasmin mutations in Parkinson's disease

scientific article published on 8 September 2005

Further delineation of the association signal on chromosome 5 from the first whole genome association study in Parkinson's disease

scientific article published on 15 February 2008

Genes in familial parkinsonism and their role in sporadic Parkinson's disease.

scientific article

Genetic analysis of the α2-macroglobulin gene in early-and late-onset Parkinsonʼs disease

article

Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression

scientific article published on March 2013

Genome-wide association study reveals genetic risk underlying Parkinson's disease

scientific article

Global investigation and meta-analysis of the C9orf72 (G4C2)n repeat in Parkinson disease

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Haploinsufficiency at the alpha-synuclein gene underlies phenotypic severity in familial Parkinson's disease

scientific article published on January 2003

Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease

scientific article (publication date: June 2003)

Independent and joint effects of the MAPT and SNCA genes in Parkinson disease

scientific article

Initiation and dose optimization for levodopa-carbidopa intestinal gel: Insights from phase 3 clinical trials

scientific article

Involuntary eyelid closure after STN-DBS: evidence for different pathophysiological entities

scientific article published on 20 June 2010

Involvement of the cerebellum in Parkinson disease and dementia with Lewy bodies

scientific article published on 25 April 2017

Knockdown of Hsc70-5/mortalin induces loss of synaptic mitochondria in a Drosophila Parkinson's disease model

scientific article (publication date: 2013)

LRRK2 in Parkinson's disease - drawing the curtain of penetrance: a commentary

scientific article

LRRK2: Understanding the role of common and rare variants in Parkinson's disease

scientific article

Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study

scientific article

Large-scale assessment of polyglutamine repeat expansions in Parkinson disease

scientific article

Large-scale replication and heterogeneity in Parkinson disease genetic loci

scientific article

Long-Term Effect of GPi-DBS in a Patient With Generalized Dystonia Due to GLUT1 Deficiency Syndrome.

scientific article

Long-term follow-up of subthalamic nucleus stimulation in glucocerebrosidase-associated Parkinson's disease

scientific article published on 17 March 2012

Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease

scientific article

Management of Parkinson's Disease 20 Years from Now: Towards Digital Health Pathways

article

Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease

scientific article published in September 2017

Methods in Neuroepidemiology Characterization of European Longitudinal Cohort Studies in Parkinson's Disease--Report of the JPND Working Group BioLoC-PD.

scientific article published on 3 November 2015

Mitochondrial Morphology, Function and Homeostasis Are Impaired by Expression of an N-terminal Calpain Cleavage Fragment of Ataxin-3

scholarly article by Tina Harmuth published in January 2018

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2.

scientific article published on 24 November 2015

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2.

scientific article published on 27 December 2016

Mitochondrial protein quality control by the proteasome involves ubiquitination and the protease Omi

scientific article published on 24 March 2008

Mitochondrial translation initiation factor 3 gene polymorphism associated with Parkinson's disease

scientific article published on 11 January 2007

Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1.

scientific article

Mutation analyses and association studies to assess the role of the presenilin-associated rhomboid-like gene in Parkinson's disease

scientific article published on 8 December 2015

Mutation analysis of the neurofilament M gene in Parkinson's disease

scientific article (publication date: 13 November 2003)

NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases

scientific article published on 17 May 2017

Neurofilament L gene is not a genetic factor of sporadic and familial Parkinson's disease

scientific article published in September 2002

Neuromuscular correlates of subthalamic stimulation and upper limb freezing in Parkinson's disease

scientific article published on 28 February 2015

New developments in diagnosis and treatment of Parkinson's disease--from basic science to clinical applications.

scientific article

Nigral stimulation for resistant axial motor impairment in Parkinson’s disease? A randomized controlled trial ⬇️

scientific article published on June 11, 2013

Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7).

scientific article published on October 2004

Olfactory neuron-specific expression of A30P α-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages

scientific article

Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice

scientific article

Parkinson's disease: one biochemical pathway to fit all genes?

scientific article

Periphilin is a novel interactor of synphilin-1, a protein implicated in Parkinson's disease

scientific article

Polymorphisms in the interleukin-1 alpha and beta genes and the risk for Parkinson's disease

scientific article

Population-specific frequencies for LRRK2 susceptibility variants in the Genetic Epidemiology of Parkinson's Disease (GEO-PD) Consortium

scientific article

Prodromal Markers in Parkinson's Disease: Limitations in Longitudinal Studies and Lessons Learned

scientific article

Protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants

scientific article published on 17 August 2013

Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1

scientific journal article

Reply: No evidence for rare TRAP1 mutations influencing the risk of idiopathic Parkinson's disease

scientific article

Review: Familial Parkinson's disease--genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease

scientific article published on June 2008

Role of sepiapterin reductase gene at the PARK3 locus in Parkinson's disease

scientific article published on 22 July 2011

Severe muscular fasciculations as an uncommon side-effect due to microdefect of an extension wire in deep brain stimulation

scientific article published in October 2009

Severe orthostatic dysregulation associated with Wolfram syndrome

scientific article published on 19 May 2010

Short- and long-term outcome of chronic pallidal neurostimulation in monogenic isolated dystonia

scientific article published on 4 February 2015

Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene

scientific article

Somatoform disorder or neurological syndrome? Complex mental and movement disorder and autonomic dysfunction in a 65-year-old patient - Case 1/2011

scientific article published on 14 January 2011

Spectrum of phenotypes and genotypes in Parkinson's disease

scientific article

Subthalamic nucleus stimulation restores the efferent cortical drive to muscle in parallel to functional motor improvement.

scientific article

Sustained improvement of obsessive-compulsive disorder by deep brain stimulation in a woman with residual schizophrenia.

scientific article published on 13 August 2008

TREM2 R47H variant and risk of essential tremor: a cross-sectional international multicenter study

scientific article published on 24 December 2014

The COMT Val/Met polymorphism modulates effects of tDCS on response inhibition

scientific article published on 24 November 2014

The GBAP1 pseudogene acts as a ceRNA for the glucocerebrosidase gene GBA by sponging miR-22-3p

scientific article published on 5 October 2017

The Luxembourg Parkinson's Study: A Comprehensive Approach for Stratification and Early Diagnosis

scholarly article by Geraldine Hipp et al published 2018 in Frontiers in Aging Neuroscience

The NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2

scientific article published on 4 September 2015

The Use of Primary Human Fibroblasts for Monitoring Mitochondrial Phenotypes in the Field of Parkinson's Disease ⬇️

scientific article published on October 3, 2012

The genetic architecture of mitochondrial dysfunction in Parkinson's disease

scientific article published on 25 January 2018

The hallmarks of Parkinson's disease

scientific article published on 10 June 2013

The modulation of Amyotrophic Lateral Sclerosis risk by ataxin-2 intermediate polyglutamine expansions is a specific effect

scientific article published on 25 August 2011

The proteasomal subunit S6 ATPase is a novel synphilin-1 interacting protein--implications for Parkinson's disease

scientific article

The role of synphilin-1 in synaptic function and protein degradation

scientific article

The subthalamic nucleus modulates the early phase of probabilistic classification learning

scientific article published on 10 April 2014

Therapeutic strategies for Parkinson's disease based on data derived from genetic research

scientific article

Transcranial ultrasound in different monogenetic subtypes of Parkinson's disease

scientific article

Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice

scientific article published in February 2010

UCHL1 is a Parkinson's disease susceptibility gene

scientific article published in April 2004

Vertebral artery dissection presenting with ispilateral acute C5 and C6 sensorimotor radiculopathy: A case report

scientific article published on 3 September 2008

Paulina is supported by:

About Paulina

Help