Search filters

List of works by Margreet Kloppenburg

282 CARTILAGE LOSS AND PAIN ARE INDEPENDENT RISK FACTORS IN THE EVOLUTION OF EROSIVE HAND OSTEOARTHRITIS

43 EROSIVE THUMB BASE OSTEOARTHRITIS IN SYMPTOMATIC COMMUNITY-DWELLING ADULTS: THE KEELE CLINICAL ASSESSMENT STUDIES

scientific article published in September 2011

A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22

scientific journal article

A genome-wide linkage scan reveals CD53 as an important regulator of innate TNF-alpha levels

scientific article

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

scientific article

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function

scientific article

Accelerated metacarpal bone mineral density loss is associated with radiographic progressive hand osteoarthritis

scientific article

Acromegalic arthropathy in various stages of the disease: an MRI study

scientific article

Activity limitations in the lower extremities in patients with osteoarthritis: the modifying effects of illness perceptions and mental health

scientific article published on 5 June 2006

Adipocyte-derived lipids modulate CD4+ T-cell function

scientific article published on 24 April 2013

Adipocytes from the infrapatellar fat pad of OA patients modulate CD4+ T cell cytokine production

scientific article published on 23 November 2011

Adipocytes modulate the phenotype of human macrophages through secreted lipids

scientific article published in July 2013

Adiposity and hand osteoarthritis: the Netherlands Epidemiology of Obesity study

scientific article published on 22 January 2014

Aesthetic dissatisfaction in patients with hand osteoarthritis and its impact on daily life

scientific article

An OMERACT Initiative Toward Consensus to Identify and Characterize Candidate Contextual Factors: Report from the Contextual Factors Working Group

scientific article published on May 2017

An emerging player in knee osteoarthritis: the infrapatellar fat pad.

scientific article published on January 2013

An innovative care model coordinated by a physical therapist and nurse practitioner for osteoarthritis of the hip and knee in specialist care: a prospective study

scientific article published on 17 January 2013

Are baseline high molecular weight adiponectin levels associated with radiographic progression in rheumatoid arthritis and osteoarthritis?

scientific article published in April 2014

Arthropathy in long-term cured acromegaly is characterised by osteophytes without joint space narrowing: a comparison with generalised osteoarthritis

scientific article published on 3 December 2010

Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies

scientific article

Association between leptin, adiponectin and resistin and long-term progression of hand osteoarthritis

scientific article published on 6 April 2011

Association between several clinical and radiological determinants with long-term clinical progression and good prognosis of lower limb osteoarthritis

scientific article (publication date: 2011)

Association between weight or body mass index and hand osteoarthritis: a systematic review

scientific article published on 31 May 2009

Association of matrilin-3 polymorphisms with spinal disc degeneration and osteoarthritis of the first carpometacarpal joint of the hand

scientific article published on 5 January 2006

Association of pain in knee osteoarthritis with distinct patterns of synovitis

scientific article

Atlas for the OMERACT thumb base osteoarthritis MRI scoring system (TOMS). ⬇️

scientific article published on 8 February 2018

Automated image analysis of hand radiographs reveals widened joint spaces in patients with long-term control of acromegaly: relation to disease activity and symptoms

scientific article published on 14 December 2011

Automatic quantification of osteoarthritis in hand radiographs: validation of a new method to measure joint space width

article by R. van 't Klooster et al published January 2008 in Osteoarthritis and Cartilage

Automatic radiographic quantification of hand osteoarthritis; accuracy and sensitivity to change in joint space width in a phantom and cadaver study

scientific article published on 11 February 2011

Bakers' cyst and tibiofemoral abnormalities are more distinctive MRI features of symptomatic osteoarthritis than patellofemoral abnormalities

scientific article published on 17 May 2016

Bioactive lipids in osteoarthritis: risk or benefit?

scientific article published on 13 October 2017

Body mass index and alignment and their interaction as risk factors for progression of knees with radiographic signs of osteoarthritis

scientific article published on 16 June 2011

Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features

scientific article

Bone marrow lesions and synovitis on MRI associate with radiographic progression after 2 years in hand osteoarthritis

scientific article published on 20 June 2016

Bone marrow lesions on magnetic resonance imaging in hand osteoarthritis are associated with pain and interact with synovitis

scientific article published on 12 February 2017

Brief Report: Association of Inflammation With Development of Erosions in Patients With Hand Osteoarthritis: A Prospective Ultrasonography Study

scientific article published on 28 September 2015

CHECK (Cohort Hip and Cohort Knee): similarities and differences with the Osteoarthritis Initiative

scientific article

Carboplatin with cyclophosphamide in patients with advanced ovarian cancer: an efficacy and quality-adjusted survival analysis

scientific article

Changes in outcome measures for impairment, activity limitation, and participation restriction over two years in osteoarthritis of the lower extremities

Characterization of gangliosides from fish brain ⬇️

scientific article published on July 14, 1970

Characterization of synovial mast cells in knee osteoarthritis: association with clinical parameters

scientific article published on 6 December 2015

Cis-acting elements reinforcing the activity of the estrogen-response element in the very-low-density apolipoprotein II gene promoter

scientific article published on April 1994

Clinical burden of erosive hand osteoarthritis and its relationship to nodes

scientific article published on 21 April 2010

Clinical osteoarthritis predicts physical and psychological QoL in acromegaly patients

scientific article

Clustering of hand osteoarthritis progression and its relationship to progression of osteoarthritis at the knee

scientific article published on 23 February 2013

Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis

scientific article

Coping styles and disability in patients with hand osteoarthritis

scientific article published on 10 September 2015

Corrigendum to “A genome-wide association study identifies a common variant near the GPR22 gene as a new locus involved in prevalence and progression of osteoarthritis” [Bone. 44S2 (2009) S224]

article

Cross-cultural validation of the ICOAP and physical function short forms of the HOOS and KOOS in a multi-country study of patients with hip and knee osteoarthritis

scientific article published on 3 August 2016

Cross-sectional and predictive associations between plasma adipokines and radiographic signs of early-stage knee osteoarthritis: data from CHECK.

scientific article

Degree of synovitis on MRI by comprehensive whole knee semi-quantitative scoring method correlates with histologic and macroscopic features of synovial tissue inflammation in knee osteoarthritis

scientific article published on 21 December 2013

Development and Reliability of the OMERACT Thumb Base Osteoarthritis Magnetic Resonance Imaging Scoring System ⬇️

scientific article published on March 2017

Do Comorbidities Play a Role in Hand Osteoarthritis Disease Burden? Data from the Hand Osteoarthritis in Secondary Care Cohort

scientific article published on 15 September 2017

Do MRI features at baseline predict radiographic joint space narrowing in the medial compartment of the osteoarthritic knee 2 years later?

scientific article published on 20 June 2008

Do knee abnormalities visualised on MRI explain knee pain in knee osteoarthritis? A systematic review

scientific article published on 09 September 2010

Do knee osteoarthritis and fat-free mass interact in their impact on health-related quality of life in men? Results from a population-based cohort

scientific article published in July 2015

EULAR evidence-based recommendations for the diagnosis of hand osteoarthritis: report of a task force of ESCISIT.

scientific article published on 04 February 2008

EULAR recommendations for the use of imaging in the clinical management of peripheral joint osteoarthritis ⬇️

scientific article published on 07 April 2017

Early local swelling and tenderness are associated with large-joint damage after 8 years of treatment to target in patients with recent-onset rheumatoid arthritis

scientific article published in April 2013

Effect of medial tibial plateau alignment on serial radiographs on the capacity to predict progression of knee osteoarthritis

scientific article published in February 2008

Effectiveness of intramuscular corticosteroid injection versus placebo injection in patients with hip osteoarthritis: design of a randomized double-blinded controlled trial

scientific article

Efficacy and safety of non-pharmacological, pharmacological and surgical treatment for hand osteoarthritis: a systematic literature review informing the 2018 update of the EULAR recommendations for the management of hand osteoarthritis

scholarly article by Féline P B Kroon et al published 2018 in RMD open

Efficacy of hydroxychloroquine in hand osteoarthritis: a randomized, double blind, placebo-controlled trial

scientific article published on 10 November 2017

Erosive hand osteoarthritis: its prevalence and clinical impact in the general population and symptomatic hand osteoarthritis

scientific article

Erosive osteoarthritis: a more severe form of radiographic hand osteoarthritis rather than a distinct entity?

scientific article

Evolution of synovitis in osteoarthritic knees and its association with clinical features

scientific article published on June 2016

Factors associated with the orthopaedic surgeon's decision to recommend total joint replacement in hip and knee osteoarthritis: an international cross-sectional study of 1905 patients ⬇️

scientific article published on 11 July 2018

Fatty acids, lipid mediators, and T-cell function

scientific article

Fixed-flexion knee radiography: the sensitivity to detect knee joint space narrowing in osteoarthritis

article by S. Botha-Scheepers et al published March 2007 in Osteoarthritis and Cartilage

Follow-up study of inflammatory ultrasound features in hand osteoarthritis over a period of 3 months: variable as well as constant

scientific article

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand

scientific article published on 30 August 2017

Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

scientific article

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

scientific article published on February 2016

Hand osteoarthritis--a heterogeneous disorder

scientific article

Hand osteoarthritis--an increasing need for treatment and rehabilitation

scientific article published on March 2007

Hand osteoarthritis-nonpharmacological and pharmacological treatments

scientific article published on 28 January 2014

High prevalence of vertebral fractures despite normal bone mineral density in patients with long-term controlled acromegaly

scholarly article by M J E Wassenaar et al published April 2011 in European Journal of Endocrinology

How old is "too old" for translational research?

scientific article

Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis

scientific article published on 11 March 2008

Identification of factors associated with the development of knee osteoarthritis in a young to middle-aged cohort of patients with knee complaints

scientific article published on 13 September 2014

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study ⬇️

scientific article published on July 3, 2012

Identifying Trajectories of Pain Severity in Early Symptomatic Knee Osteoarthritis: A 5-year Followup of the Cohort Hip and Cohort Knee (CHECK) Study

scientific article

Illness perceptions in patients with osteoarthritis: change over time and association with disability

scientific article

Impact of self-reported comorbidity on physical and mental health status in early symptomatic osteoarthritis: the CHECK (Cohort Hip and Cohort Knee) study

scientific article published on 23 October 2012

In erosive hand osteoarthritis more inflammatory signs on ultrasound are found than in the rest of hand osteoarthritis

scientific article published on 20 July 2012

Incidence, prevalence, natural course and prognosis of patellofemoral osteoarthritis: the Cohort Hip and Cohort Knee study

scientific article

Inflammatory Cells in Patients with Endstage Knee Osteoarthritis: A Comparison between the Synovium and the Infrapatellar Fat Pad.

scientific article

Inflammatory features of infrapatellar fat pad in rheumatoid arthritis versus osteoarthritis reveal mostly qualitative differences

scholarly article by Anja Jacoba de Jong et al published 5 August 2017 in Annals of the Rheumatic Diseases

Inflammatory ultrasound features show independent associations with progression of structural damage after over 2 years of follow-up in patients with hand osteoarthritis

scientific article published on 29 April 2014

Instruments Measuring Pain, Physical Function, or Patient's Global Assessment in Hand Osteoarthritis: A Systematic Literature Search

scientific article published on 15 October 2015

Interleukin-1 gene cluster variants with innate cytokine production profiles and osteoarthritis in subjects from the Genetics, Osteoarthritis and Progression Study

scientific article

Intramuscular glucocorticoid injection versus placebo injection in hip osteoarthritis: a 12-week blinded randomised controlled trial

scientific article published on 7 March 2018

Lack of high BMI-related features in adipocytes and inflammatory cells in the infrapatellar fat pad (IFP).

scientific article published on 11 August 2017

Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand

scientific article published on June 2009

Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis

scientific article published on 10 December 2010

Letter: Septicaemia due to porcine streptococci

scientific article published on December 1975

Limitations in daily activities are the major determinant of reduced health-related quality of life in patients with hand osteoarthritis

scientific article

Lipid mediators of inflammation in rheumatoid arthritis and osteoarthritis

scientific article published on December 2015

Longitudinal Reliability of the OMERACT Thumb Base Osteoarthritis Magnetic Resonance Imaging Scoring System (TOMS) ⬇️

scholarly article by Féline Kroon et al published 15 December 2018 in The Journal of Rheumatology

Low innate production of interleukin-1beta and interleukin-6 is associated with the absence of osteoarthritis in old age.

scientific article published on 22 April 2010

Magnetic Resonance Imaging in Hand Osteoarthritis: Intraobserver Reliability and Criterion Validity for Clinical and Structural Characteristics

scientific article

Magnetic resonance imaging of knee cartilage using a water selective balanced steady-state free precession sequence

scientific article

Measuring functioning in patients with hand osteoarthritis--content comparison of questionnaires based on the International Classification of Functioning, Disability and Health (ICF).

scientific article published on 2 May 2006

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance

scientific article published on 23 July 2014

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22

scientific article

Metabolic health in families enriched for longevity is associated with low prevalence of hand osteoarthritis and influences OA biomarker profiles

scientific article published on 27 October 2012

Metabolic profiling reveals differences in concentrations of oxylipins and fatty acids secreted by the infrapatellar fat pad of donors with end-stage osteoarthritis and normal donors

scientific article published on October 2013

Mortality in osteoarthritis patients

scientific article published on 2 September 2014

Muckle-Wells syndrome: a rare periodic fever syndrome

scientific article

Mutation analysis of candidate genes within the 2q33.3 linkage area for familial early-onset generalised osteoarthritis.

scientific article

Neurologic outcome of surgical and conservative treatment of rheumatoid cervical spine subluxation: a systematic review

scientific article published on December 2009

No association between impaired glucose metabolism and osteoarthritis

scientific article published on 12 April 2016

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis

scientific article

Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects

scientific article published on 19 September 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

OARSI Clinical Trials Recommendations: Hand imaging in clinical trials in osteoarthritis

scientific article

OARSI-OMERACT definition of relevant radiological progression in hip/knee osteoarthritis.

scientific article published on 09 February 2009

OARSI/OMERACT initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis. An OMERACT 10 Special Interest Group

scientific article published on August 2011

Osteoarthritis development is induced by increased dietary cholesterol and can be inhibited by atorvastatin in APOE*3Leiden.CETP mice--a translational model for atherosclerosis

scientific article published on 26 April 2013

Osteoarthritis of the knee: association between clinical features and MR imaging findings

scientific article

Osteoarthritis research priorities: a report from a EULAR ad hoc expert committee

scientific article published on 13 March 2014

Osteoarthritis: Inflammation and fibrosis in adipose tissue of osteoarthritic joints

scientific article

Osteophytes and joint space narrowing are independently associated with pain in finger joints in hand osteoarthritis

scientific article published on 8 July 2011

Pain in hand osteoarthritis is associated with inflammation: the value of ultrasound

scientific article published on 14 May 2010

Patient perspective of hand osteoarthritis in relation to concepts covered by instruments measuring functioning: a qualitative European multicentre study

scientific article published on 2 September 2008

Pattern of involvement and risk profile of symptomatic erosive osteoarthritis: results of an exploratory population-based study

scientific article published in April 2012

Positive association between increased popliteal artery vessel wall thickness and generalized osteoarthritis: is OA also part of the metabolic syndrome?

scientific article published on 03 July 2009

Predictive value of MRI features for development of radiographic osteoarthritis in a cohort of participants with pre-radiographic knee osteoarthritis-the CHECK study

scientific article published on 25 October 2016

Pretreatment insulin-like growth factor-I concentrations predict radiographic osteoarthritis in acromegalic patients with long-term cured disease

scientific article published on 14 April 2009

Prevalence of cartilaginous tumours as an incidental finding on MRI of the knee

scientific article

Profiling the secretion of soluble mediators by end stage osteoarthritis synovial tissue explants reveals a reduced responsiveness to an inflammatory trigger

scientific article

Progression of acromegalic arthropathy despite long-term biochemical control: a prospective, radiological study

scientific article published on 29 May 2012

Progression of vertebral fractures despite long-term biochemical control of acromegaly: a prospective follow-up study

scientific article published on 30 September 2013

Radiographic progression of knee osteoarthritis is associated with MRI abnormalities in both the patellofemoral and tibiofemoral joint

scientific article

Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium

scientific article published on 6 November 2010

Reference curves for the Australian/Canadian Hand Osteoarthritis Index in the middle-aged Dutch population

scientific article published on 11 January 2017

Reference curves for the Australian/Canadian hand osteoarthritis index (AUSCAN) in the general population

article

Relationship between insulin-like growth factor-1 and radiographic disease in patients with primary osteoarthritis: a systematic review

scientific article

Relationship between the functional exon 3 deleted growth hormone receptor polymorphism and symptomatic osteoarthritis in women

scientific article published on 5 June 2013

Reliability of cluster results for different types of time adjustments in complex disease research

scientific article published in January 2008

Reliability, sensitivity to change and feasibility of three radiographic scoring methods for hand osteoarthritis

scientific article published on 10 May 2011

Report from the OMERACT Hand Osteoarthritis Special Interest Group: advances and future research priorities

scientific article published on 15 January 2014

Report from the OMERACT Hand Osteoarthritis Working Group: Set of Core Domains and Preliminary Set of Instruments for Use in Clinical Trials and Observational Studies

scientific article published on July 2015

Research in hand osteoarthritis: time for reappraisal and demand for new strategies. An opinion paper

scientific article published on 14 March 2007

Rheumatoid arthritis: epidural enhancement as an underestimated cause of subaxial cervical spinal stenosis

scientific article

Risk factors for progression in hand osteoarthritis: a systematic review

scientific article

Risk factors in familial osteoarthritis: the GARP sibling study

scientific article

Role of rheumatology clinical nurse specialists in optimizing management of hand osteoarthritis during daily practice in secondary care: an observational study

scientific article published on November 2011

Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.

scientific article published on 13 April 2014

Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles

scientific article published on 13 July 2005

Statins and fibrates do not affect development of spontaneous cartilage damage in STR/Ort mice

scientific article published on 23 November 2013

Strong linkage on 2q33.3 to familial early-onset generalized osteoarthritis and a consideration of two positional candidate genes

scientific article

Symptomatic and chondroprotective treatment with collagen derivatives in osteoarthritis: a systematic review

scientific article

Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

scientific article published on 07 September 2012

Systemic and local factors are involved in the evolution of erosions in hand osteoarthritis

scientific article published on 19 November 2010

Testing the druggable endothelial differentiation gene 2 knee osteoarthritis genetic factor for replication in a wide range of sample collections

scientific article published on 14 July 2008

The DOT1L rs12982744 polymorphism is associated with osteoarthritis of the hip with genome-wide statistical significance in males

scientific article published on 16 March 2013

The Netherlands Epidemiology of Obesity (NEO) study: study design and data collection

scientific article

The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis ⬇️

The additional value of different radiographic views on identification of early radiographic hip and knee osteoarthritis and its progression: the CHECK (cohort hip and cohort knee) study

scientific article published on 26 January 2017

The development of a preliminary ultrasonographic scoring system for features of hand osteoarthritis

scientific article published on 17 August 2007

The diagnostic performance of MRI in osteoarthritis: a systematic review and meta-analysis

scientific article published on 19 October 2011

The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype.

scientific article

The model of erosive hand osteoarthritis

scientific article

The prevalence of erosive osteoarthritis in carpometacarpal joints and its clinical burden in symptomatic community-dwelling adults

scientific article

The relationship between the MRI features of mild osteoarthritis in the patellofemoral and tibiofemoral compartments of the knee

article by Peter R. Kornaat et al published 8 March 2005 in European Radiology

The role of fat mass and skeletal muscle mass in knee osteoarthritis is different for men and women: the NEO study

scientific article published on 12 December 2013

The role of interleukin 10 promoter polymorphisms in the susceptibility of distal interphalangeal osteoarthritis

scientific article published in August 2005

The role of pain and functional impairment in the decision to recommend total joint replacement in hip and knee osteoarthritis: an international cross-sectional study of 1909 patients. Report of the OARSI-OMERACT Task Force on total joint replacemen

scientific article

The transcriptional landscape of age in human peripheral blood

scientific article

Treatment with TNF-α inhibitor infliximab might reduce hand osteoarthritis in patients with rheumatoid arthritis

scientific article published on 5 August 2010

Two phenotypes of arthropathy in long-term controlled acromegaly? A comparison between patients with and without joint space narrowing (JSN).

scientific article published on 26 June 2013

Updating the OMERACT filter: implications for imaging and soluble biomarkers

scientific article

Using the common sense model of illness perceptions to examine osteoarthritis change: a 6-year longitudinal study

scientific article published in January 2010

Validity of joint space width measurements in hand osteoarthritis

scientific article published on 5 September 2011

Validity, reliability, responsiveness and feasibility of four hand mobility measures in hand osteoarthritis

scientific article published on 14 December 2017

What is the evidence for the presence of a therapeutic window of opportunity in rheumatoid arthritis? A systematic literature review

scientific article published on 09 April 2013

What is the predictive value of MRI for the occurrence of knee replacement surgery in knee osteoarthritis?

scientific article published on 25 July 2013

Worsening of pain and function over 5 years in individuals with 'early' OA is related to structural damage: data from the Osteoarthritis Initiative and CHECK (Cohort Hip & Cohort Knee) study

scientific article

Paulina is supported by:

About Paulina

Help