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List of works by Harold Snieder

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article

24 h urinary free cortisol in large-scale epidemiological studies: short-term and long-term stability and sources of variability

scientific article published on 4 May 2014

52 Genetic Loci Influencing Myocardial Mass

scientific article

A 15-year longitudinal study on ambulatory blood pressure tracking from childhood to early adulthood

scientific article published on 27 March 2009

A Comparison of Heritability Estimates by Classical Twin Modeling and Based on Genome-Wide Genetic Relatedness for Cardiac Conduction Traits

scientific article published on 17 October 2017

A Genome-Wide Methylation Study of Severe Vitamin D Deficiency in African American Adolescents

scientific article published on December 7, 2012

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure

scientific article published on 23 May 2020

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A gene-environment interaction model of stress-induced hypertension

scientific article

A genome-wide approach to children's aggressive behavior: The EAGLE consortium

scientific article published on 18 June 2015

A genome-wide methylation study on essential hypertension in young African American males

scientific article

A genome-wide methylation study on obesity: differential variability and differential methylation

scientific article published on 17 April 2013

A longitudinal study in youth of heart rate variability at rest and in response to stress

scientific article published on 10 March 2009

A longitudinal study of blood pressure variability in African-American and European American youth

scientific article published on April 2010

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A twin study of auditory processing indicates that dichotic listening ability is a strongly heritable trait.

scientific article

Activation markers of coagulation and fibrinolysis in twins: heritability of the prethrombotic state

scientific article published on 01 February 2002

Adhesion molecule polymorphisms and pulse wave velocity in American youth

scientific article published on October 2008

Adiponectin gene ADIPOQ SNP associations with serum adiponectin in two female populations and effects of SNPs on promoter activity.

scientific article published on 04 June 2008

Adverse childhood experiences and blood pressure trajectories from childhood to young adulthood: the Georgia stress and Heart study.

scientific article published on 9 April 2015

Aging Trajectories in Different Body Systems Share Common Environmental Etiology: The Healthy Aging Twin Study (HATS).

scientific article published on February 2016

An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype

scientific article published on 8 December 2016

An epigenome-wide association study identifies multiple DNA methylation markers of exposure to endocrine disruptors

scientific article published on 08 September 2020

An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression

scientific article published on 5 January 2018

Anger suppression and adiposity modulate association between ADRB2 haplotype and cardiovascular stress reactivity

scientific article published in March 2006

Are Twins and Singletons Comparable? A Study of Disease-related and Lifestyle Characteristics in Adult Women

article by Toby Andrew et al published December 2001 in Twin Research and Human Genetics

Are hypertriglyceridemia and low HDL causal factors in the development of insulin resistance?

scientific article published on 07 January 2014

Association between 9p21 genetic variants and mortality risk in a prospective cohort of patients with type 2 diabetes (ZODIAC-15).

scientific article published on 7 November 2012

Association between angiotensin II type I receptor polymorphism and resting hemodynamics in black and white youth

scientific article published on 01 January 2002

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

scientific article published on 23 December 2011

Association between methylation of the SLC6A4 promoter region in peripheral blood leukocytes and methylation in amygdala tissue.

scientific article published in April 2014

Association of alpha1A adrenergic receptor gene variants on chromosome 8p21 with human stage 2 hypertension

scientific article

Association of common JAK2 variants with body fat, insulin sensitivity and lipid profile

scientific article published on February 2008

Association of two DRD2 gene polymorphisms with acute and tardive antipsychotic-induced movement disorders in young Caucasian patients

scientific article published on July 13, 2011

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

scientific article

Author Correction: Causal Pathways from Blood Pressure to Larger QRS Amplitudes: a Mendelian Randomization Study.

scientific article published on 3 July 2018

Autonomic Dysfunction and Blood Pressure in Glaucoma Patients: The Lifelines Cohort Study

scientific article published on 01 September 2020

Beta2-adrenergic receptor gene and resting hemodynamics in European and African American youth

scientific article published in November 2002

Beyond genome-wide association studies: new strategies for identifying genetic determinants of hypertension

scientific article published on December 2011

Bioinformatic Prioritization and Functional Annotation of GWAS-Based Candidate Genes for Primary Open-Angle Glaucoma

scientific article published on 14 June 2022

Bivariate Genome-Wide Association Study of Depressive Symptoms with Type 2 Diabetes and Quantitative Glycemic Traits

scientific article published on 27 December 2017

Bivariate genetic modeling of cardiovascular stress reactivity: does stress uncover genetic variance?

scientific article published on 17 May 2007

Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression

scientific article published on 09 January 2019

Blood Eosinophil Count and Metabolic, Cardiac and Pulmonary Outcomes: A Mendelian Randomization Study

scientific article published on 6 March 2018

CD36 gene promoter polymorphisms are associated with low density lipoprotein-cholesterol in normal twins and after a low-calorie diet in obese subjects

scientific article published in December 2008

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

scientific article published on 29 September 2017

CUBN as a novel locus for end-stage renal disease: insights from renal transplantation

scientific article

Cardiovascular characteristics in American youth with prehypertension

scientific article published on 01 October 2007

Causal Pathways from Blood Pressure to Larger Qrs Amplitudes a Mendelian Randomization Study.

scientific article

Change of genetic determinants of left ventricular structure in adolescence: longitudinal evidence from the Georgia cardiovascular twin study

scientific article published on 24 April 2008

Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins

scientific article

Clinical response to antipsychotic drug treatment: Association study of polymorphisms in six candidate genes

scientific article published on March 3, 2012

Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu

scientific article

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium

scientific article published on 13 September 2017

Cohort Profile: The National Academy of Sciences-National Research Council Twin Registry (NAS-NRC Twin Registry).

scientific article

Combined association and linkage analysis applied to the APOE locus

scientific article published in May 2004

Common STAT3 variants are not associated with obesity or insulin resistance in female twins

scientific article

Common genes contribute to depressive symptoms and heart rate variability: the Twins Heart Study

scientific article

Common genetic contributions to depressive symptoms and inflammatory markers in middle-aged men: the Twins Heart Study

scientific article

Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies

scientific article

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

scientific article

Common variants near melanocortin 4 receptor are associated with general and visceral adiposity in European- and African-American youth

scientific article

Common variation in the NOS1AP gene is associated with drug-induced QT prolongation and ventricular arrhythmia

scientific article published on 06 June 2012

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking

scientific article published on 19 September 2019

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article published on 26 May 2017

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

scientific article published on November 2016

Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

scientific article published in September 2017

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis

scientific article published on 30 March 2016

DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies

scientific article published on 25 November 2020

DNA methylation markers associated with type 2 diabetes, fasting glucose and HbA1c levels: a systematic review and replication in a case-control sample of the Lifelines study.

scientific article published on 21 November 2017

DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring

scientific article

DNA methylation of the LY86 gene is associated with obesity, insulin resistance, and inflammation

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Determinants of pulse wave velocity trajectories from youth to young adulthood: the Georgia Stress and Heart Study

Development of general and central obesity from childhood into early adulthood in African American and European American males and females with a family history of cardiovascular disease

scientific article published on 01 April 2004

Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents

scientific article published on 26 February 2015

Different gene sets contribute to different symptom dimensions of depression and anxiety

scientific article published on May 9, 2012

Differential influence of family history of hypertension and premature myocardial infarction on systolic blood pressure and left ventricular mass trajectories in youth

scientific article published in June 2003

Discovery and fine mapping of serum protein loci through transethnic meta-analysis

scientific article

Dissecting the genetic architecture of the cardiovascular and renal stress response

scientific article

Does refining the phenotype improve replication rates? A review and replication of candidate gene studies on Major Depressive Disorder and Chronic Major Depressive Disorder

scientific article

Dominance genetic variation contributes little to the missing heritability for human complex traits

scientific article

Early Determinants of Childhood Blood Pressure at the Age of 6 Years: The GECKO Drenthe and ABCD Study Birth Cohorts

scientific article published on 10 November 2020

Educational level and risk of chronic kidney disease: longitudinal data from the PREVEND study

scientific article published on 12 December 2018

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

scientific article published on 01 June 2019

Effects of NOS3 Glu298Asp polymorphism on hemodynamic reactivity to stress: influences of ethnicity and obesity

scientific article

Effects of angiotensinogen and angiotensin II type I receptor genes on blood pressure and left ventricular mass trajectories in multiethnic youth

scientific article

Effects of dopamine receptor type 1 and Gs protein alpha subunit gene polymorphisms on blood pressure at rest and in response to stress

scientific article published in August 2006

Emergence of novel genetic effects on blood pressure and hemodynamics in adolescence: the Georgia Cardiovascular Twin Study

scientific article published on 27 March 2006

Endocrine disrupting chemicals during diet-induced weight loss - a post-hoc analysis of the LOWER study

scientific article published on 09 October 2020

Endothelin-1 gene Lys198Asn polymorphism and blood pressure reactivity

scientific article published on 8 September 2003

Endothelin-1 gene and progression of blood pressure and left ventricular mass: longitudinal findings in youth

scientific article published on 25 October 2004

Eosinophil Count Is a Common Factor for Complex Metabolic and Pulmonary Traits and Diseases: The LifeLines Cohort Study

scientific article

Epigenome-wide meta-analysis of DNA methylation and childhood asthma

scientific article published in December 2018

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

scientific article published on 02 March 2020

Erratum: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

article

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

scientific article published on 2 August 2017

Ethnic and gender differences in ambulatory blood pressure trajectories: results from a 15-year longitudinal study in youth and young adults

scientific article published on 27 November 2006

Ethnic differences and heritability of heart rate variability in African- and European American youth

scientific article published on 31 August 2005

Ethnic differences in heart rate variability: does ultralow-frequency heart rate variability really measure autonomic tone?

scientific article published in September 2006

Ethnic differences in resting heart rate variability: a systematic review and meta-analysis

scientific article

Ethnic differences in the association of birth weight and blood pressure: the Georgia cardiovascular twin study

scientific article

Evaluation of a genetic risk score based on creatinine-estimated glomerular filtration rate and its association with kidney outcomes

scientific article published on 01 October 2018

Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women

scientific article

Evidence for a QTL on chromosome 19 influencing LDL cholesterol levels in the general population.

scientific article published in November 2003

Evidence for independent heritability of the glycation gap (glycosylation gap) fraction of HbA1c in nondiabetic twins

scientific article published in August 2006

Exposure to Endocrine Disrupting Chemicals in the Dutch general population is associated with adiposity-related traits

scientific article published on 09 June 2020

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youth

scientific article

Familial Aggregation of CKD and Heritability of Kidney Biomarkers in the General Population: The Lifelines Cohort Study

scientific article published on 16 December 2020

Familial aggregation and childhood blood pressure

scientific article published on January 2015

Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

scientific article

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

scientific article published in Nature Communications

GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence

scientific article

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

scientific article published on 21 June 2013

GWASinspector: comprehensive quality control of genome-wide association study results

scientific article published on 08 January 2021

Gender Differences in the Genetic Factors Responsible for Variation in Bone Density and Ultrasound

scientific article published on 01 April 2002

Gene-Lifestyle Interactions in Obesity

scientific article (publication date: 2012)

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

scientific article

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

scientific article published on 20 February 2014

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

Genetic Influence on Blood Pressure and Underlying Hemodynamics Measured at Rest and During Stress

scientific article published on April 10, 2013

Genetic Risk Scores for Complex Disease Traits in Youth

scientific article published on 11 June 2020

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic and Environmental Effects on Gene Expression Signatures of Blood Pressure: A Transcriptome-Wide Twin Study

scientific article published on 8 January 2018

Genetic and Environmental Influences on Blood Pressure and Body Mass Index in the National Academy of Sciences-National Research Council World War II Veteran Twin Registry

scientific article published on 28 September 2020

Genetic and environmental determinants of lipid profile in black and white youth: a study of four candidate genes.

scientific article published in January 2005

Genetic and environmental influences on anger expression, John Henryism, and stressful life events: the Georgia Cardiovascular Twin Study

scientific article

Genetic and environmental influences on blood pressure and body mass index in Han Chinese: a twin study

scientific article published on November 4, 2010

Genetic and environmental influences on blood pressure variability: a study in twins.

scientific article published on April 2013

Genetic and environmental influences on lipids, lipoproteins, and apolipoproteins: effects of menopause

scientific article

Genetic and environmental influences on stability and change in baseline levels of C-reactive protein: A longitudinal twin study.

scientific article published on 31 August 2017

Genetic and environmental influences on systemic markers of inflammation in middle-aged male twins

scientific article published on 20 February 2008

Genetic architecture of tissue-type plasminogen activator and plasminogen activator inhibitor-1.

scientific article published on September 2008

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

scientific article

Genetic association study of childhood aggression across raters, instruments, and age

scientific article

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic contribution to cartilage volume in women: a classical twin study

scientific article published on 27 June 2003

Genetic contribution to renal function and electrolyte balance: a twin study

scientific article published in September 2002

Genetic correlation of exercise with heart rate and respiratory sinus arrhythmia

scientific article

Genetic epidemiological approaches in the study of risk factors for cardiovascular disease

scientific article published on January 2004

Genetic evidence of assortative mating in humans

scholarly article

Genetic influence on age at first birth of female twins born in the UK, 1919-68.

scientific article published on 3 August 2015

Genetic influence on blood pressure measured in the office, under laboratory stress and during real life

scientific article published on November 11, 2010

Genetic influence on early age-related maculopathy: a twin study

scientific article published on April 2002

Genetic influences on cardiovascular stress reactivity

scientific article published on 04 December 2009

Genetic influences on daytime and night-time blood pressure: similarities and differences

scientific article published on December 2009

Genetic influences on fibrinogen, tissue plasminogen activator-antigen and von Willebrand factor in males and females

scientific article published in March 2006

Genetic influences on heart rate variability at rest and during stress

scientific article published on 17 February 2009

Genetic loci influencing kidney function and chronic kidney disease

scientific article

Genetic pre-screening for glaucoma in population-based epidemiology: protocol for a double-blind prospective screening study within Lifelines (EyeLife)

scientific article published on 07 January 2021

Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index

scientific article

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

scientific article published on 18 April 2016

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genetics and the heart rate response to exercise.

scientific article

Genetics in psychosomatic medicine: research designs and statistical approaches

scientific article published on 8 February 2007

Genetics of coronary artery disease: genome-wide association studies and beyond

scientific article published on 23 May 2012

Genetics of fibrin clot structure: a twin study.

scientific article published on 6 November 2003

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-Wide Association Scan of Serum Urea in European Populations Identifies Two Novel Loci

scientific article published on 26 February 2019

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

scientific article

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

scientific article published on 7 September 2022

Genome-wide association analysis identifies multiple loci related to resting heart rate

scientific article

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

scientific article published on 30 January 2017

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM

scientific article

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association meta-analysis of age at first cannabis use

scientific article published on 19 August 2018

Genome-wide association meta-analysis of childhood and adolescent internalising symptoms

scientific article

Genome-wide association studies and beyond: what's next in blood pressure genetics?

scientific article published on 8 November 2010

Genome-wide association study identifies eight loci associated with blood pressure

scientific article (publication date: June 2009)

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

scientific article published on 16 October 2011

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension

scientific article

Genome-wide association study of kidney function decline in individuals of European descent

scientific article

Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium

scientific article

Genome-wide genetic homogeneity between sexes and populations for human height and body mass index

scientific article published on 22 October 2015

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

scientific article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genomic Mismatch at LIMS1 Locus and Kidney Allograft Rejection

scientific article published on 01 May 2019

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

scientific article published on 23 September 2016

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

scientific article published on 24 April 2017

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

article

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

scientific article published on 11 May 2020

Genotype-covariate interaction effects and the heritability of adult body mass index

scientific article published on 10 July 2017

Glaucoma in large-scale population-based epidemiology: a questionnaire-based proxy

scientific article published on 18 June 2020

Glycotoxin and autoantibodies are additive environmentally determined predictors of type 1 diabetes: a twin and population study

scientific article published on 6 March 2012

Gompertz’ survivorship law as an intrinsic principle of aging

scientific article published on March 2, 2012

Growth of left ventricular mass in African American and European American youth

scientific article published in May 2002

Heart rate variability and its relation to chronic kidney disease: Results from the PREVEND Study

scientific article published on 2 January 2018

Heart rate variability in adolescents: relations to physical activity, fitness, and adiposity

scientific article published in November 2005

Heritabilities of apolipoprotein and lipid levels in three countries

scientific article

Heritabilities of lipids in young European American and African American twins

scientific article

Heritability analyses show visit-to-visit blood pressure variability reflects different pathological phenotypes in younger and older adults: evidence from UK twins

scientific article published in December 2013

Heritability and genetic and environmental correlations of heart rate variability and baroreceptor reflex sensitivity with ambulatory and beat-to-beat blood pressure

scientific article published in Scientific Reports

Heritability and genetic correlations of heart rate variability at rest and during stress in the Oman Family Study

scientific article published on 19 March 2018

Heritability and genetic correlations of obesity indices with ambulatory and office beat-to-beat blood pressure in the Oman Family Study

scientific article published on 13 March 2020

Heritability and stability of resting blood pressure

scientific article published in October 2005

Heritability and the Genetic Correlation of Heart Rate Variability and Blood Pressure in >29 000 Families: The Lifelines Cohort Study

scientific article published on 24 August 2020

Heritability of Blood Pressure and Hemodynamics in African- and European-American Youth

scientific article published on April 28, 2003

Heritability of QT interval: how much is explained by genes for resting heart rate?

scientific article published on 20 November 2007

Heritability of arterial stiffness in black and white American youth and young adults

scientific article published on October 2007

Heritability of carotid intima-media thickness: a twin study

scientific article published on 6 September 2007

Heritability of glaucoma and glaucoma-related endophenotypes: systematic review and meta-analysis protocol

scientific article published on 28 February 2018

Heritability of obesity-related phenotypes and association with adiponectin gene polymorphisms in the Chinese national twin registry.

scientific article published on 18 February 2010

Heritability of strabismus: genetic influence is specific to eso-deviation and independent of refractive error

scientific article published on 13 June 2012

Heritability of thyroid peroxidase autoantibody levels in type 1 diabetes: evidence from discordant twin pairs

scientific article published on 13 June 2015

Hidden heritability due to heterogeneity across seven populations

scientific article published on 11 September 2017

Human fertility, molecular genetics, and natural selection in modern societies.

scientific article published on 3 June 2015

Identification of QTLs for serum lipid levels in a female sib-pair cohort: a novel application to improve the power of two-locus linkage analysis

article

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Identification, Heritability, and Relation With Gene Expression of Novel DNA Methylation Loci for Blood Pressure

scientific article published on 10 June 2020

Identifying genetic variants for heart rate variability in the acetylcholine pathway

scientific article

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

scientific article published on 12 September 2017

In Silico Post Genome-Wide Association Studies Analysis of C-Reactive Protein Loci Suggests an Important Role for Interferons

scientific article published on 9 March 2015

Influence of Dietary Approaches to Stop Hypertension-Type Diet, Known Genetic Variants and Their Interplay on Blood Pressure in Early Childhood: ABCD Study

scientific article published on 02 December 2019

Influence of common variants in FTO and near INSIG2 and MC4R on growth curves for adiposity in African– and European–American youth

scientific article published on May 5, 2011

Influence of common variants near INSIG2, in FTO, and near MC4R genes on overweight and the metabolic profile in adolescence: the TRAILS (TRacking Adolescents' Individual Lives Survey) Study

scientific article published on 9 December 2009

Influence of the eNOS gene on development of blood pressure and left ventricular mass: longitudinal findings in multiethnic youth

scientific article published in September 2005

Insulin resistance syndrome and left ventricular mass in healthy young people

scientific article published in August 2002

Interactions between uncoupling protein 2 gene polymorphisms, obesity and alcohol intake on liver function: a large meta-analysed population-based study

scientific article published on December 2015

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study

scientific article

Joint Linkage and Association of Six Single-Nucleotide Polymorphisms in the Factor XIII-A Subunit Gene Point to V34L As the Main Functional Locus

article

KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern

scientific article published on 05 December 2019

Lectin complement pathway gene profile of the donor and recipient does not influence graft outcome after kidney transplantation

scientific article

Letter to editor: Reply on question of Marques JR et al. regarding the paper entitled: "The LifeLines cohort study: Prevalence and treatment of cardiovascular disease and risk factors"

scientific article published on 01 November 2019

Leukocyte telomere length in healthy Caucasian and African-American adolescents: relationships with race, sex, adiposity, adipokines, and physical activity

scientific article

Level of an advanced glycated end product is genetically determined: a study of normal twins

scientific article published in September 2003

Lifestyle and Socioeconomic‐Status Modify the Effects of ADRB2 and NOS3 on Adiposity in European‐American and African‐American Adolescents

scientific article published on October 7, 2010

Lipidomics, Atrial Conduction, and Body Mass Index

scientific article published on 15 July 2019

Loci influencing blood pressure identified using a cardiovascular gene-centric array

scientific article published on 8 January 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

scientific article

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium

scientific article published on October 2017

Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts

scientific article

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

scientific article

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

scientific article

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

article

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

scientific article

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

scientific article published on 30 October 2020

Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study

scientific article published on 12 April 2017

Modeling with measured genotypes: effects of the vitamin D receptor gene, age, and latent genetic and environmental factors on bone mineral density

scientific article published in March 2004

Moderators of blood pressure development from childhood to adulthood: a 10-year longitudinal study

scientific article published in December 2002

Modulation of genetic associations with serum urate levels by body-mass-index in humans

scientific article

Mortality prediction models in the adult critically ill: A scoping review

scientific article published on 26 December 2019

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

scientific article published on 12 November 2019

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

scientific article published in Nature Communications

Multilocus analyses of Renin-Angiotensin-aldosterone system gene variants on blood pressure at rest and during behavioral stress in young normotensive subjects

scientific article published on 20 November 2006

NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality

scientific article published on 30 March 2017

NPHP1 (Nephrocystin-1) Gene Deletions Cause Adult-Onset ESRD.

scientific article published on 13 April 2018

Neuroticism and morning cortisol secretion: both heritable, but no shared genetic influences

scientific article published on 11 August 2009

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders

scientific article published on 29 July 2019

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Novel genes for QTc interval. How much heritability is explained, and how much is left to find?

scientific article

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

scientific article published on 18 June 2018

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

scientific article published on 12 October 2020

Obesity related methylation changes in DNA of peripheral blood leukocytes

scientific article published on December 21, 2010

Obesity reveals an association between blood pressure and the G-protein beta3-subunit gene: a study of female dizygotic twins

scientific article published in July 2004

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

scientific article published on 28 November 2016

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

scientific article published in Nature Communications

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

scientific article

Parsimonious Correction of Heart Rate Variability for Its Dependency on Heart Rate

scientific article published on 26 September 2016

Personality Polygenes, Positive Affect, and Life Satisfaction

scientific article published on 22 August 2016

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Phenotypic and genotypic correlation between myopia and intelligence

scientific article published on 06 April 2017

Pleiotropic effects of lipid genes on plasma glucose, HbA1c, and HOMA-IR levels

scientific article published on 10 April 2014

Pleiotropic genes for metabolic syndrome and inflammation

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Pleiotropy of C-reactive protein gene polymorphisms with C-reactive protein levels and heart rate variability in healthy male twins

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Population-based values and abnormalities of the electrocardiogram in the general Dutch population: The LifeLines Cohort Study.

scientific article published on 12 June 2017

Prevalence and risk factors of dry eye in 79,866 participants of the population-based Lifelines cohort study in the Netherlands

scientific article published on 03 May 2020

Prevalence of electrocardiographic unrecognized myocardial infarction and its association with mortality

scientific article published on 17 May 2017

Proopiomelanocortin gene variants are associated with serum leptin and body fat in a normal female population

scientific article published in June 2005

Prostasin: a possible candidate gene for human hypertension

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Protein tyrosine phosphatase-1B gene PTPN1: selection of tagging single nucleotide polymorphisms and association with body fat, insulin sensitivity, and the metabolic syndrome in a normal female population

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Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Pulse wave velocity in elastic and muscular arteries: tracking stability and association with anthropometric and hemodynamic measurements

scientific article published on 23 June 2016

QCEWAS: automated quality control of results of epigenome-wide association studies.

scientific article published on 24 January 2017

QCGWAS: A flexible R package for automated quality control of genome-wide association results

scientific article published on 05 January 2014

REMOVED: A bivariate Genome Wide Association Study (GWAS) of depressive symptoms and lipid levels has identified pleiotropic gene loci

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Reference values of heart rate variability from 10-second resting electrocardiograms: the Lifelines Cohort Study

scientific article published on 09 September 2019

Relation Between Leisure Time, Commuting, and Occupational Physical Activity With Blood Pressure in 125 402 Adults: The Lifelines Cohort

scientific article published on 12 February 2020

Relationships of cardiovascular phenotypes with healthy weight, at risk of overweight, and overweight in US youths

scientific article published in January 2008

Representativeness of the LifeLines Cohort Study

scientific article published on 2 September 2015

Role of gene-stress interactions in gene-finding studies.

scientific article published on January 2008

SNP-Based Heritability Estimates of Common and Specific Variance in Self- and Informant-Reported Neuroticism Scales

scientific article published on 15 December 2016

Serotonin transporter gene, depressive symptoms, and interleukin-6.

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Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Sex differences and heritability of two indices of heart rate dynamics: a twin study

scientific article published in April 2007

Sex-Based Differences in Unrecognized Myocardial Infarction

scientific article published on 23 June 2020

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

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Sexual dimorphism in the genetic influence on human childlessness

scientific article published on 05 July 2017

Specific genetic influences on nighttime blood pressure

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Stress-induced sodium excretion: a new intermediate phenotype to study the early genetic etiology of hypertension?

scientific article published on 22 December 2008

Sympathetic nervous system, genes and human essential hypertension

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Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

The G protein-coupled receptor kinase 4 gene affects blood pressure in young normotensive twins

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The G protein-coupled receptor kinase 4 gene modulates stress-induced sodium excretion in black normotensive adolescents

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The Georgia Cardiovascular Twin Study

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The Georgia Cardiovascular Twin Study: influence of genetic predisposition and chronic stress on risk for cardiovascular disease and type 2 diabetes

scientific article published on December 2006

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

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The SH2B gene is associated with serum leptin and body fat in normal female twins.

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The Twin Interdisciplinary Neuroticism Study

scientific article published on 28 November 2012

The age-dependency of genetic and environmental influences on serum cytokine levels: a twin study

scientific article published on 4 June 2012

The association of depression and anxiety with cardiac autonomic activity: The role of confounding effects of antidepressants

scientific article published on 17 October 2019

The association of genetic factors, educational attainment, and their interaction, with kidney function outcomes

scientific article published on 22 October 2020

The diagnostic accuracy of clinical examination for estimating cardiac index in critically ill patients: the Simple Intensive Care Studies-I

scientific article published on 31 January 2019

The effects of bariatric surgery on clinical profile, DNA methylation, and ageing in severely obese patients

scientific article published on 20 January 2020

The effects of polymorphisms in genes from the renin–angiotensin, bradykinin, and fibrinolytic systems on plasma t-PA and PAI-1 levels are dependent on environmental context

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The genetic architecture of sporadic and multiple consecutive miscarriage

scientific article published on 25 November 2020

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The genetics of depression: successful genome-wide association studies introduce new challenges

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The heritability of dry eye disease in a female twin cohort

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The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population

scientific article published on 28 March 2019

The inheritance of peripapillary atrophy

scientific article published in June 2007

The interaction of genetic predisposition and socioeconomic position with type 2 diabetes mellitus: cross-sectional and longitudinal analyses from the Lifelines Cohort and Biobank Study

scientific article published on 29 January 2018

The interaction of socioeconomic position and type 2 diabetes mellitus family history: a cross-sectional analysis of the Lifelines Cohort and Biobank Study

scientific article published on 7 April 2017

The narrow-sense and common single nucleotide polymorphism heritability of early repolarization

The power of genetic diversity in genome-wide association studies of lipids

The relation between insulin resistance and hemostasis: pleiotropic genes and common environment

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The relationship between neuroticism and inflammatory markers: a twin study

scientific article published on 15 April 2014

Timing of Stressful Life Events Affects Stability and Change of Neuroticism

Toll-Like Receptor Family Polymorphisms Are Associated with Primary Renal Diseases but Not with Renal Outcomes Following Kidney Transplantation

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Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

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Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

scientific article published in Nature Communications

Transcriptomics- and Genomics-Guided Drug Repurposing for the Treatment of Vesicular Hand Eczema

scientific article published in 2024

Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9-based approach

scientific article published on 16 July 2020

Twenty-Five Novel Loci for Carotid Intima-Media Thickness: A Genome-Wide Association Study in >45 000 Individuals and Meta-Analysis of >100 000 Individuals

scientific article published on 02 December 2021

Two-locus Linkage Analysis Applied to Putative Quantitative Trait Loci for Lipoprotein(a) Levels

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UMOD as a susceptibility gene for end-stage renal disease

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Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression

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Update on G-protein polymorphisms in hypertension

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Uric acid in major depressive and anxiety disorders

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Urinary norepinephrine and epinephrine excretion rates are heritable, but not associated with office and ambulatory blood pressure

scientific article published on July 12, 2012

Urinary prostasin excretion is associated with adiposity in nonhypertensive African-American adolescents

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Using twin studies to label disease as genetic or environmental is inappropriate

scientific article published on May 2002

Validating the doubly weighted genetic risk score for the prediction of type 2 diabetes in the Lifelines and Estonian Biobank cohorts

scientific article published on 14 June 2020

Validity of (Ultra-)Short Recordings for Heart Rate Variability Measurements

scientific article published on 28 September 2015

Variance Components Models for Analysis of Big Family Data of Health Outcomes in the Lifelines Cohort Study

scientific article published on 01 February 2019

lodGWAS: a software package for genome-wide association analysis of biomarkers with a limit of detection

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