List of works by Anna Köttgen

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article

<i>NAT8</i> Variants, N-Acetylated Amino Acids, and Progression of CKD

scientific article published on 30 December 2020

A COL4A5 mutation with glomerular disease and signs of chronic thrombotic microangiopathy

scientific article

A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population ⬇️

scientific article published on 8 October 2015

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A genetic risk score for thyroid peroxidase antibodies associates with clinical thyroid disease in community-based populations

scientific article published on 26 February 2015

A multi-source data integration approach reveals novel associations between metabolites and renal outcomes in the German Chronic Kidney Disease study

scientific article published on 27 September 2019

A polygenic score predicts CKD across ancestries

scientific article published in 2022

ABCG transporters and disease

scientific article published on 13 June 2011

Against all odds: blended phenotypes of three single-gene defects

scientific article published on 27 January 2016

Age, gender, and race effects on cystatin C levels in US adolescents

scientific article published on 24 September 2008

An Empirical Approach to Signature Peptide Choice for Selected Reaction Monitoring: Quantification of Uromodulin in Urine

scientific article published on 20 November 2015

Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study

article published in 2019

Association of Serum Uromodulin with Death, Cardiovascular Events, and Kidney Failure in CKD

scientific article published on 14 April 2020

Association of apolipoprotein A1 and B with kidney function and chronic kidney disease in two multiethnic population samples

scientific article

Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.

scientific article

Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing

scientific article published on 31 May 2012

Association of relative telomere length with cardiovascular disease in a large chronic kidney disease cohort: the GCKD study

scientific article published on 14 August 2015

Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC Study

scientific article

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

scientific article

Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study

scientific article

Combination of mouse models and genomewide association studies highlights novel genes associated with human kidney function

scientific article

Common genetic variants associate with serum phosphorus concentration

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

scientific article

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

scientific article

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

scientific article

Common variants in KCNN3 are associated with lone atrial fibrillation

scientific article

Common variants in Mendelian kidney disease genes and their association with renal function

scientific article published on 12 September 2013

Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels

scientific article

Comparison of serum concentrations of β-trace protein, β2-microglobulin, cystatin C, and creatinine in the US population

scientific article published on 18 January 2013

Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations

scientific article

Correction: Heart Failure in a Cohort of Patients with Chronic Kidney Disease: The GCKD Study

scientific article published on 15 June 2015

Correlates of kidney stone disease differ by race in a multi-ethnic middle-aged population: the ARIC study

scientific article

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article published on 26 May 2017

Defining incident chronic kidney disease in the research setting: The ARIC Study

scientific article published on 17 June 2009

Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population.

scientific article

Evolving importance of kidney disease: from subspecialty to global health burden

scientific article published on 31 May 2013

From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function.

scientific article published on 12 December 2017

GSTM1 Deletion Exaggerates Kidney Injury in Experimental Mouse Models and Confers the Protective Effect of Cruciferous Vegetables in Mice and Humans

scientific article published on 14 November 2019

GenToS: Use of Orthologous Gene Information to Prioritize Signals from Human GWAS.

scientific article

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic loci associated with renal function measures and chronic kidney disease in children: the Pediatric Investigation for Genetic Factors Linked with Renal Progression Consortium

scientific article published on 28 September 2015

Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study

scientific article published on 29 May 2015

Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans

scientific article published on 20 January 2020

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetic, Environmental, and Disease-Associated Correlates of Vitamin D Status in Children with CKD.

scientific article published on 16 June 2016

Genetics of serum urate concentrations and gout in a high-risk population, patients with chronic kidney disease

scientific article published in Scientific Reports

Genome-Wide Association Studies in Nephrology Research ⬇️

scientific article published on August 21, 2010

Genome-Wide Association Studies of CKD and Related Traits

scientific article published on 14 May 2020

Genome-Wide Association of Copy Number Polymorphisms and Kidney Function

scientific article

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

scientific article published in Nature Communications

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association and functional follow-up reveals new loci for kidney function

scientific article

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association studies in nephrology: using known associations for data checks

scientific article

Genome-wide association studies in pediatric chronic kidney disease

scientific article

Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels

scientific article

Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism

scientific article

Genome-wide association study of PR interval

scientific article

Genome-wide association study of blood pressure and hypertension

scientific journal article

Genome-wide association study of kidney function decline in individuals of European descent

scientific article

Genomic imbalances in pediatric patients with chronic kidney disease

scientific article published on 20 April 2015

Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy

scientific article published on 20 April 2017

Glycaemic control and antidiabetic therapy in patients with diabetes mellitus and chronic kidney disease - cross-sectional data from the German Chronic Kidney Disease (GCKD) cohort

scientific article

Gout in Older Adults: The Atherosclerosis Risk in Communities Study

scientific article published on 28 December 2015

Heart failure in a cohort of patients with chronic kidney disease: the GCKD study

scientific article

High-normal albuminuria and risk of heart failure in the community

scientific article

Human metabolic individuality in biomedical and pharmaceutical research

scientific article (publication date: 31 August 2011)

Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals

scientific article

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

scholarly article

Impact of repeated measures and sample selection on genome-wide association studies of fasting glucose

scientific article

Incident gout in women and association with obesity in the Atherosclerosis Risk in Communities (ARIC) Study

scientific article

Influence of DNA extraction methods on relative telomere length measurements and its impact on epidemiological studies

scientific article

Insights into kidney diseases from genome-wide association studies

scientific article

Integration of GWAS Summary Statistics and Gene Expression Reveals Target Cell Types Underlying Kidney Function Traits

scientific article published on 06 August 2020

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

scientific article published on 8 September 2012

Is High-Density Lipoprotein Cholesterol Causally Related to Kidney Function? Evidence From Genetic Epidemiological Studies

scientific article published on 29 September 2016

Kidney function estimated from serum creatinine and cystatin C and peripheral arterial disease in NHANES 1999-2002.

scientific article published on 31 May 2009

Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels

scientific article published in Nature Communications

Lower urinary connective tissue growth factor levels and incident CKD stage 3 in the general population

scientific article

Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program

scientific article published on 26 August 2019

Mendelian Randomization as an Approach to Assess Causality Using Observational Data

scientific article

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

scientific article

Modulation of genetic associations with serum urate levels by body-mass-index in humans

scientific article

Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors

scientific article

Multiple loci associated with indices of renal function and chronic kidney disease

scientific journal article

NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality

scientific article published on 30 March 2017

Nephrolithiasis as a Risk Factor for CKD: The Atherosclerosis Risk in Communities Study

scientific article

Neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule 1 (KIM-1) as predictors of incident CKD stage 3: the Atherosclerosis Risk in Communities (ARIC) Study

scientific article

New genetic insights into kidney physiology and disease

scientific article published on 03 December 2020

New loci associated with kidney function and chronic kidney disease

scientific article

Obesity and younger age at gout onset in a community-based cohort

scientific article

Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium

scientific article published on 6 March 2013

Physical Function, Hyperuricemia, and Gout in Older Adults

scientific article

Plasma Urate and Risk of a Hospital Stay with AKI: The Atherosclerosis Risk in Communities Study

scientific article published on 25 February 2015

Prevalence and Risk Factors of Thyroid Dysfunction in Older Adults in the Community

scientific article published on 11 September 2019

Prevalence of kidney disease in anaemia differs by GFR-estimating method: the Third National Health and Nutrition Examination Survey (1988-94).

scientific article

Quality assurance in the pre-analytical phase of human urine samples by (1)H NMR spectroscopy

scientific article published on 8 August 2015

Race differences in access to health care and disparities in incident chronic kidney disease in the US.

scientific article

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

scientific article published on 9 April 2018

Reliability and sensitivity of the self-report of physician-diagnosed gout in the campaign against cancer and heart disease and the atherosclerosis risk in the community cohorts

scientific article published on December 2010

Role of BMI in the Association of the TCF7L2 rs7903146 Variant with Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study

scientific article

Serum cystatin C in the United States: the Third National Health and Nutrition Examination Survey (NHANES III)

scientific article

TCF7L2 variants associate with CKD progression and renal function in population-based cohorts

scientific article published on 23 July 2008

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

The Loss of GSTM1 Associates with Kidney Failure and Heart Failure

scientific article

The MYH9/APOL1 region and chronic kidney disease in European-Americans

scientific article

The association of podocin R229Q polymorphism with increased albuminuria or reduced estimated GFR in a large population-based sample of US adults

scientific article published on 21 May 2008

The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis

scientific article published on 30 March 2020

The rs2231142 variant of the ABCG2 gene is associated with uric acid levels and gout among Japanese people

scientific article

The transcription factor 7-like 2 (TCF7L2) polymorphism may be associated with focal arteriolar narrowing in Caucasians with hypertension or without diabetes: the ARIC Study

scientific article

Thyroid function, reduced kidney function and incident chronic kidney disease in a community-based population: the Atherosclerosis Risk in Communities study

scientific article published on 18 August 2016

Trefoil factor 3 predicts incident chronic kidney disease: a case-control study nested within the Atherosclerosis Risk in Communities (ARIC) study

scientific article

Uromodulin levels associate with a common UMOD variant and risk for incident CKD.

scientific article

Validated SNPs for eGFR and their associations with albuminuria

scientific article

Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry ⬇️

scientific article published on 13 July 2009

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