List of works by Bruce M. Psaty

10-year follow-up of subclinical cardiovascular disease and risk of coronary heart disease in the Cardiovascular Health Study

scientific article published in January 2006

17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status

scientific article

2013 ACC/AHA guideline on the treatment of blood cholesterol: a fresh interpretation of old evidence

scientific article published on 01 February 2014

27-year time trends in dementia incidence in Europe and the US: the Alzheimer Cohorts Consortium

scientific article published on 01 July 2020

27th Bethesda Conference: matching the intensity of risk factor management with the hazard for coronary disease events. Task Force 2. Clinical epidemiology: the conceptual basis for interpreting risk factors

scientific article published on April 1996

52 Genetic Loci Influencing Myocardial Mass

scientific article

73-OR: Clonal Hematopoiesis of Indeterminate Potential (CHIP), Glycemic Traits, and Type 2 Diabetes (T2D) Risk

scientific article published in 2021

<i>ZBTB33</i> is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing

scientific article published on 14 July 2021

A Comprehensive Evaluation of the Genetic Architecture of Sudden Cardiac Arrest

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

scientific journal article

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A common prothrombin variant (20210 G to A) increases the risk of myocardial infarction in young women

scientific article published on 01 September 1997

A community-based approach to preventing alcohol use among adolescents on an American Indian reservation.

scientific article

A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies

scientific article published in December 2022

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium

scientific article published on 05 May 2013

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

scientific article published on 02 August 2019

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology

scientific article published on 14 January 2019

A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3

scientific article

A genome-wide association study meta-analysis of clinical fracture in 10,012 African American women

scientific article

A genome-wide association study of aging

scientific article

A genome-wide association study of depressive symptoms

scientific journal article

A genome-wide association study of early menopause and the combined impact of identified variants

scientific article published on 9 January 2013

A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium

scientific article published on 30 December 2016

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

A large-scale exome array analysis of venous thromboembolism

scientific article published on 19 January 2019

A lifecycle approach to the evaluation of FDA approval methods and regulatory actions: opportunities provided by a new IOM report

scientific article published on 01 June 2012

A low-frequency variant in MAPK14 provides mechanistic evidence of a link with myeloperoxidase: a prognostic cardiovascular risk marker

scientific article

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

scientific article

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

scientific article

A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

scientific article

A meta-analysis of genome-wide association studies identifies multiple longevity genes

scientific article published on 14 August 2019

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function

scientific article

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A new era of cardiovascular disease epidemiology

scientific article published on 01 November 2007

A novel Alzheimer disease locus located near the gene encoding tau protein.

scientific article

A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains

scientific article

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A regression model for longitudinal change in the presence of measurement error.

scientific article published in January 2002

A review of the association of estrogens and progestins with cardiovascular disease in postmenopausal women

scientific article published on June 1993

A screening study of drug-drug interactions in cerivastatin users: an adverse effect of clopidogrel

scientific article published on 14 March 2012

ABO genotype and risk of thrombotic events and hemorrhagic stroke

scientific article

ACE-inhibitor therapy and nosocomial pneumonia.

scientific article published in November 1999

ADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article

Absence of anti-HMG-CoA reductase autoantibodies in severe self-limited statin-related myopathy

scientific article

Absolute Rates of Heart Failure, Coronary Heart Disease, and Stroke in Chronic Kidney Disease: An Analysis of 3 Community-Based Cohort Studies

scientific article published on 21 December 2016

Abstract 14629: Rare Variants for Electrocardiographic Traits Identify Arrhythmia Susceptibility Genes

scientific article published in 2020

Activating communities for health promotion: a process evaluation method

scientific article published on 01 April 1993

Acute respiratory distress syndrome after trauma: development and validation of a predictive model.

scientific article

Addressing the Opioid Epidemic - Opportunities in the Postmarketing Setting

scientific article published on April 2017

Advanced glycation/glycoxidation endproduct carboxymethyl-lysine and incidence of coronary heart disease and stroke in older adults

scientific article

Advances in regulatory science at the Food and Drug Administration

scientific article published in May 2013

African ancestry, socioeconomic status, and kidney function in elderly African Americans: a genetic admixture analysis

scientific article

Agreement between nosologist and cardiovascular health study review of deaths: implications of coding differences

scientific article

Alcohol consumption and risk and prognosis of atrial fibrillation among older adults: the Cardiovascular Health Study

scientific article published in February 2007

Alcohol consumption and risk of coronary heart disease in older adults: the Cardiovascular Health Study

scientific article published in January 2006

Amlodipine or lisinopril was not better than chlorthalidone in lowering CHD risk in hypertension

scientific article published on July 2003

Amlodipine or lisinopril was not better than chlorthalidone in lowering CHD risk in hypertension

scientific article published in November 2003

Amount of leisure-time physical activity and risk of nonfatal myocardial infarction

scientific article (publication date: June 2007)

An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group

scientific article published on 27 May 2016

An Empirical Exploration of a Conceptual Model for Community-Based Health-Promotion

scientific article published on 01 January 1992

An approach to several problems in using large databases for population-based case-ontrol studies of the therapeutic efficacy and safety of anti-hypertensive medicines

scientific article published on 01 April 1991

Analysis commons, a team approach to discovery in a big-data environment for genetic epidemiology

scientific article published in October 2017

Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease.

scientific article published on 24 April 2018

Angiotensin II type 1 receptor polymorphisms in the cardiovascular health study: relation to blood pressure, ethnicity, and cardiovascular events

scientific article published in December 2002

Angiotensin-converting enzyme inhibitors and cognitive decline in older adults with hypertension: results from the Cardiovascular Health Study

scientific article

Angiotensinogen Met235Thr polymorphism, angiotensin-converting enzyme inhibitor therapy, and the risk of nonfatal stroke or myocardial infarction in hypertensive patients

scientific article published on December 2003

Antidepressant Use and Subclinical Measures of Atherosclerosis: The Multi-Ethnic Study of Atherosclerosis

scientific article published on 6 June 2016

Antidiabetic treatment trends in a cohort of elderly people with diabetes. The cardiovascular health study, 1989-1997.

scientific article published in May 1999

Antihypertensive drug therapies and the risk of ischemic stroke

scientific article

Antihypertensive medication use and change in kidney function in elderly adults: a marginal structural model analysis

scientific article published on 8 September 2011

Antihypertensive medications and C-reactive protein in the multi-ethnic study of atherosclerosis

scientific article published in March 2007

Antihypertensive treatment with ACE inhibitors or beta-blockers and risk of incident atrial fibrillation in a general hypertensive population

scientific article published on 05 March 2009

Are drugs within a class interchangeable?

scientific article

Ascertainment of warfarin and aspirin use by medical record review compared with automated pharmacy data

scientific article

Assessing response bias in random-digit dialling surveys: the telephone-prefix method

scientific article published in June 1992

Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data

scientific article published in March 2022

Assessing the use of medications in the elderly: methods and initial experience in the Cardiovascular Health Study. The Cardiovascular Health Study Collaborative Research Group

scientific article published in June 1992

Assessing the validity of a survey of the restaurant health promotion environment

scientific article published on November 1994

Assessment and control for confounding by indication in observational studies.

scientific article published in June 1999

Assessment of gene-by-sex interaction effect on bone mineral density

scientific article (publication date: October 2012)

Assessment of incidence of inhibitors in patients with haemophilia.

scientific article

Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study

article published in 2019

Assessment of trans-fatty acid intake with a food frequency questionnaire and validation with adipose tissue levels of trans-fatty acids

scientific article published on 01 December 1998

Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

scientific article

Association between blood pressure level and the risk of myocardial infarction, stroke, and total mortality: the cardiovascular health study

scientific article published on 01 May 2001

Association between cardiovascular outcomes and antihypertensive drug treatment in older women

scientific article

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

scientific article published on 23 December 2011

Association between levels of blood pressure and measures of subclinical disease multi-ethnic study of atherosclerosis

scientific article published in November 2006

Association of 25-Hydroxyvitamin D status and genetic variation in the vitamin D metabolic pathway with FEV1 in the Framingham Heart Study

scientific article published in July 2015

Association of Alcohol Consumption After Development of Heart Failure With Survival Among Older Adults in the Cardiovascular Health Study

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

scientific article published on 04 September 2019

Association of Blood Pressure Trajectory With Mortality, Incident Cardiovascular Disease, and Heart Failure in the Cardiovascular Health Study

scientific article published on 10 March 2017

Association of CD14 with incident dementia and markers of brain aging and injury

scientific article published on 09 December 2019

Association of Cardiometabolic Multimorbidity With Mortality

scientific article

Association of Cardiovascular Biomarkers With Incident Heart Failure With Preserved and Reduced Ejection Fraction

scientific article published on 10 January 2018

Association of Normal Systolic Blood Pressure Level With Cardiovascular Disease in the Absence of Risk Factors

scientific article published on 10 June 2020

Association of Rare Loss-Of-Function Alleles in HAL, Serum Histidine: Levels and Incident Coronary Heart Disease

scientific article published on 8 January 2015

Association of beta-blocker use with mortality among patients with congestive heart failure in the Cardiovascular Health Study (CHS)

scientific article published on 01 September 2005

Association of body mass index, diabetes, hypertension, and blood pressure levels with risk of permanent atrial fibrillation

scientific article (publication date: February 2013)

Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and all-cause mortality: the Cardiovascular Health Study

scientific article published on 18 June 2007

Association of cholesterol with stroke risk varies in stroke subtypes and patient subgroups

scientific article published in November 2004

Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity

scientific article

Association of exome sequences with plasma C-reactive protein levels in >9000 participants

scientific article

Association of fibrinogen and coagulation factors VII and VIII with cardiovascular risk factors in the elderly: the Cardiovascular Health Study. Cardiovascular Health Study Investigators

scientific article published in April 1996

Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study

scientific article

Association of genetic variants and incident coronary heart disease in multiethnic cohorts: the PAGE study

scientific article published on 31 October 2011

Association of genetic variations with nonfatal venous thrombosis in postmenopausal women.

scientific article published on February 2007

Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies

scientific article published on 16 December 2012

Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium

scientific journal article

Association of heat shock proteins with all-cause mortality

scientific article published on 04 May 2012

Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals

scientific article

Association of hypothyroidism and obstructive sleep apnea

scientific article published in November 1998

Association of kidney disease measures with ischemic versus hemorrhagic strokes: pooled analyses of 4 prospective community-based cohorts

scientific article published on 29 May 2014

Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article (publication date: June 2014)

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks

scientific article

Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts

scientific article published on April 2009

Association of polymorphisms in the CRP gene with circulating C-reactive protein levels and cardiovascular events

scientific article published on 01 December 2006

Association of sick sinus syndrome with incident cardiovascular disease and mortality: the Atherosclerosis Risk in Communities study and Cardiovascular Health Study

scientific article

Association of the IGF1 gene with fasting insulin levels

scientific article published on 10 February 2016

Association of the alpha-adducin polymorphism with blood pressure and risk of myocardial infarction

scientific article published on 01 February 2000

Association of total insulin-like growth factor-I, insulin-like growth factor binding protein-1 (IGFBP-1), and IGFBP-3 levels with incident coronary events and ischemic stroke

scientific article published on 30 January 2007

Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects

Associations between NOS1AP single nucleotide polymorphisms (SNPs) and QT interval duration in four racial/ethnic groups in the Multi-Ethnic Study of Atherosclerosis (MESA)

scientific article

Associations between aspirin and other non-steroidal anti-inflammatory drugs and aortic valve or coronary artery calcification: the Multi-Ethnic Study of Atherosclerosis and the Heinz Nixdorf Recall Study

scientific article published on 14 May 2013

Associations between genetic variants in the ACE, AGT, AGTR1 and AGTR2 genes and renal function in the Multi-ethnic Study of Atherosclerosis

scientific article

Associations of Circulating Lymphocyte Subpopulations with Type 2 Diabetes: Cross-Sectional Results from the Multi-Ethnic Study of Atherosclerosis (MESA).

scientific article published on 12 October 2015

Associations of Innate and Adaptive Immune Cell Subsets With Incident Type 2 Diabetes Risk: The MESA Study

scientific article published on 01 March 2020

Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium

scientific article

Associations of Plasma Phospholipid SFAs with Total and Cause-Specific Mortality in Older Adults Differ According to SFA Chain Length

scientific article published on 23 December 2015

Associations of Vitamin D-Binding Globulin and Bioavailable Vitamin D Concentrations With Coronary Heart Disease Events: The Multi-Ethnic Study of Atherosclerosis (MESA).

scientific article published on 3 May 2017

Associations of aortic distensibility and arterial elasticity with long-term visit-to-visit blood pressure variability: the Multi-Ethnic Study of Atherosclerosis (MESA)

scientific article published on 28 March 2013

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Associations of pentraxin 3 with cardiovascular disease and all-cause death: the Cardiovascular Health Study

scientific article published on 22 January 2009

Associations of pentraxin 3 with cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis

scientific article

Associations of plasma phospholipid and dietary alpha linolenic acid with incident atrial fibrillation in older adults: the Cardiovascular Health Study

scientific article (publication date: 31 January 2013)

Associations of postmenopausal estrogen use with cardiovascular disease and its risk factors in older women. The CHS Collaborative Research Group

scientific article published on 01 November 1993

Atrial ectopy as a mediator of the association between race and atrial fibrillation

scientific article

Atrial ectopy as a predictor of incident atrial fibrillation: a cohort study

scientific article

Atrial fibrillation and cognitive decline: a longitudinal cohort study

scientific article (publication date: 9 July 2013)

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

scientific article published on 01 May 2019

Baseline depressive symptoms are not associated with clinically important levels of incident hypertension during two years of follow-up: the multi-ethnic study of atherosclerosis

scientific article

Benefits and risks of drug treatments: how to combine the best evidence on benefits with the best data about adverse effects

scientific article

Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium

scientific article

Beta blockers and the primary prevention of nonfatal myocardial infarction in patients with high blood pressure

scientific article published on 01 November 1990

Beta-blockers and primary prevention of coronary heart disease in patients with high blood pressure

scientific article published in April 1989

Beta2-adrenergic receptor genetic variants and risk of sudden cardiac death

scientific article published on 01 April 2006

Beta2-adrenergic receptor polymorphisms and risk of incident cardiovascular events in the elderly

scientific article published on 7 April 2003

Beyond hypertension toward guidelines for cardiovascular risk reduction

scientific article published on 01 November 2004

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality

scientific article published on 01 May 2019

Biomarkers of Inflammation and MRI-Defined Small Vessel Disease of the Brain: The Cardiovascular Health Study

scientific article

Black-white differences in subclinical cardiovascular disease among older adults: The cardiovascular health study

article

Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease

scientific article published on 19 August 2019

Blood Pressure Trajectory, Gait Speed, and Outcomes: The Health, Aging, and Body Composition Study

scientific article published on 03 May 2016

Blood Pressure Trajectory, Gait Speed, and Outcomes: The Health, Aging, and Body Composition Study.

scientific article

Blood Pressure and Heart Rate Measures Associated With Increased Risk of Covert Brain Infarction and Worsening Leukoaraiosis in Older Adults

scientific article published on 29 June 2017

Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis

scientific article published on 30 August 2017

Blood pressure control and risk of incident atrial fibrillation.

scientific article published on 28 August 2008

Blood pressure level and incidence of myocardial infarction among patients treated for hypertension

scientific article published on 01 September 1999

Blood pressure level and outcomes in adults aged 65 and older with prior ischemic stroke

scientific article published in September 2006

Blood pressure variability and the risk of all-cause mortality, incident myocardial infarction, and incident stroke in the cardiovascular health study

scientific article (publication date: October 2013)

Blood-pressure-lowering treatment

scientific article published on 01 July 2001

Body mass index and the risk of recurrent coronary events following acute myocardial infarction

scientific article published on 01 September 2001

Brain natriuretic peptide and insulin resistance in older adults

scientific article published on 21 April 2016

British guidelines on managing hypertension. Provide evidence, progress, and an occasional missed opportunity

scientific article published on September 1999

C-reactive protein and the 10-year incidence of coronary heart disease in older men and women: the cardiovascular health study

scientific article published on 27 June 2005

C-reactive protein, carotid intima-media thickness, and incidence of ischemic stroke in the elderly: the Cardiovascular Health Study

scientific article published on 23 June 2003

C-reactive protein, fibrinogen, and cardiovascular disease prediction

scientific article published on October 2012

CC4-03: The Use of Administrative Data and Natural Language Processing to Estimate the Incidence of Statin-related Rhabdomyolysis.

scientific article published in August 2012

COX-2 inhibitors--lessons in drug safety

scientific article published on 15 February 2005

CRP gene variation and risk of community-acquired pneumonia

scientific article

Caffeine Intake in Relation to the Risk of Primary Cardiac Arrest

scientific article published on September 1, 1997

Calcium Antagonists: Antagonists or Protagonists of Mortality in Elderly Hypertensives?

scientific article published on 01 November 1995

Calcium antagonists: not appropriate as first line antihypertensive agents

scientific article published on February 1996

Calcium antagonists: safe or unsafe?

scientific article published in April 1996

Calcium channel blocker use and gastrointestinal tract bleeding among older adults

scientific article published on 01 May 2002

Can Measures of the Grocery Store Environment Be Used to Track Community-Level Dietary Changes?

Cardiopulmonary resuscitation: celebration and challenges

scientific article published in July 2010

Cardiovascular Safety Trials of Antidiabetic Therapies to Treat Type 2 Diabetes: Perhaps Asking the Wrong Question?

scientific article published on 01 September 2019

Cardiovascular and mortality risk prediction and stratification using urinary albumin excretion in older adults ages 68–102: The cardiovascular Health Study

article

Cardiovascular disease mortality in familial forms of hypertriglyceridemia: A 20-year prospective study

scientific article

Cardiovascular disease risk status in elderly persons with renal insufficiency

scientific article published in September 2002

Cardiovascular mortality risk in chronic kidney disease: comparison of traditional and novel risk factors

scientific article

Cardiovascular risk factors and incident acute renal failure in older adults: the cardiovascular health study

scientific article published on 6 February 2008

Carotid intima-media thickness, electrocardiographic left ventricular hypertrophy, and incidence of intracerebral hemorrhage

scientific article

Carryover effects after cessation of drug treatment: trophies or dreams?

scientific article

Carvedilol was more effective than metoprolol tartrate for lowering mortality in chronic heart failure

scientific article

Case-control study of oral glucose-lowering drugs in combination with long-acting insulin and the risks of incident myocardial infarction and incident stroke

scientific article published on 8 November 2015

Case-control study of second-line therapies for type 2 diabetes in combination with metformin and the comparative risks of myocardial infarction and stroke

scientific article

Catechol-O-Methyltransferase and Cardiovascular Disease: MESA

scientific article published on 16 December 2019

Cerebral small vessel disease genomics and its implications across the lifespan

scientific article published on 08 December 2020

Cerivastatin in vitro metabolism by CYP2C8 variants found in patients experiencing rhabdomyolysis

scientific article

Cerivastatin, genetic variants, and the risk of rhabdomyolysis

scientific article

Changes in insulin-like growth factor-I and its binding proteins are associated with diabetes mellitus in older adults

scientific article published on May 2015

Characteristics and baseline clinical predictors of future fatal versus nonfatal coronary heart disease events in older adults: the Cardiovascular Health Study

scientific article

Characteristics of study design and elements that may contribute to the success of electronic safety monitoring systems

scientific article published on 29 September 2014

Characterization of cardiac mechanics and incident atrial fibrillation in participants of the Cardiovascular Health Study

scientific article published on 10 September 2020

Chlamydia pneumoniae, herpes simplex virus type 1, and cytomegalovirus and incident myocardial infarction and coronary heart disease death in older adults : the Cardiovascular Health Study

scientific article

Cholesterol Variability and Cranial Magnetic Resonance Imaging Findings in Older Adults: The Cardiovascular Health Study

scientific article published on 17 December 2019

Cholesterol ester transfer protein, interleukin-8, peroxisome proliferator activator receptor alpha, and Toll-like receptor 4 genetic variations and risk of incident nonfatal myocardial infarction and ischemic stroke

scientific article published on 09 April 2008

Cholesterol reduction and the risk for stroke in men. A meta-analysis of randomized, controlled trials

scientific article published on July 1993

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

scientific article

Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts

scientific article published on 01 July 2020

Circulating Very Long-Chain Saturated Fatty Acids and Heart Failure: The Cardiovascular Health Study

scientific article published on 01 November 2018

Circulating omega-6 polyunsaturated fatty acids and total and cause-specific mortality: the Cardiovascular Health Study

scientific article

Clinical Implications of Recent Findings from the Antihypertensive and Lipid-Lowering Treatment To Prevent Heart Attack Trial (ALLHAT) and Other Studies of Hypertension

scientific article

Clinical factors, but not C-reactive protein, predict progression of calcific aortic-valve disease: the Cardiovascular Health Study

scientific article published on 29 October 2007

Clinical implications of the World Health Organization-International Society of Hypertension statement on calcium antagonists

scientific article published on November 1997

Clinical trial design and selected drug safety issues for antibiotics used to treat community-acquired pneumonia

scientific article

Clinical trial investigators and their prescribing patterns: another dimension to the relationship between physician investigators and the pharmaceutical industry

scientific article published on 01 June 2006

Clinically silent electrocardiographic abnormalities and risk of primary cardiac arrest among hypertensive patients.

scientific article published in September 1996

Coagulation factor VIII, white matter hyperintensities and cognitive function: Results from the Cardiovascular Health Study

scientific article published on 16 November 2020

Coagulation factor XIII polymorphisms and the risk of myocardial infarction and ischaemic stroke in young women

scientific article published on 01 February 2002

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts

scientific article (publication date: February 2009)

Combined association of lipids and blood pressure in relation to incident cardiovascular disease in the elderly: the cardiovascular health study

scientific article

Common Coding Variants in Are Associated With the Nav1.8 Late Current and Cardiac Conduction

scientific article published on 01 May 2018

Common FABP4 genetic variants and plasma levels of fatty acid binding protein 4 in older adults

scientific article published on 17 September 2013

Common Genetic Determinants of Vitamin D Insufficiency: A Genome-Wide Association Study

Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities

scientific article published on 10 June 2020

Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation

scientific article published on 01 February 2019

Common VKORC1 variants are not associated with arterial or venous thrombosis

scientific article

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

scientific article

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

scientific article

Common genetic variants associate with serum phosphorus concentration

scientific article

Common genetic variation in six lipid-related and statin-related genes, statin use and risk of incident nonfatal myocardial infarction and stroke

scientific article published on August 2008

Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium

scientific article published on 8 November 2011

Common genetic variation in the prothrombin gene, hormone therapy, and incident nonfatal myocardial infarction in postmenopausal women

scientific article published on 08 February 2006

Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants.

scientific article

Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: The cardiovascular health study

scholarly article by Alexander P. Reiner et al published July 2005 in Atherosclerosis

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Common variants at ten loci influence QT interval duration in the QTGEN Study

scientific article published on 22 March 2009

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

scientific article

Common variants in KCNN3 are associated with lone atrial fibrillation

scientific article

Common variants in the CRP gene in relation to longevity and cause-specific mortality in older adults: the Cardiovascular Health Study

scientific article published on 21 September 2007

Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels

scientific article

Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease

scientific article

Common variation in cytochrome P450 epoxygenase genes and the risk of incident nonfatal myocardial infarction and ischemic stroke.

scientific article published in June 2008

Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest

scientific article published on 10 January 2014

Community-level comparisons between the grocery store environment and individual dietary practices

scientific article

Comparing a single-stage geocoding method to a multi-stage geocoding method: how much and where do they disagree?

scientific article published on 16 March 2007

Comparing methods to address bias in observational data: statin use and cardiovascular events in a US cohort.

scientific article published on 8 September 2017

Comparison of 2 Treatment Models: Precision Medicine and Preventive Medicine

scientific article published on 01 August 2018

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

scientific article

Comparison of calcium channel blockers with other classes of drugs for hypertension

scientific article

Comparison of mortality risk for electrocardiographic abnormalities in men and women with and without coronary heart disease (from the Cardiovascular Health Study).

scientific article

Comparison of self-report, hospital discharge codes, and adjudication of cardiovascular events in the Women's Health Initiative

scientific article

Concordance With Prevention Guidelines and Subsequent Cancer, Cardiovascular Disease, and Mortality: A Longitudinal Study of Older Adults

scientific article published on 17 August 2017

Conducting comparative effectiveness research on medications: the views of a practicing epidemiologist from the other Washington

scientific article published on 9 November 2011

Conflict of interest, disclosure, and trial reports

scientific article published on 01 April 2009

Congestive heart failure incidence and prognosis: case identification using central adjudication versus hospital discharge diagnoses

scientific article published on 16 June 2005

Congress responds to the IOM drug safety report--in full

scientific article published in November 2007

Contemplating ACTION--long-acting nifedipine in stable angina

scientific article published in September 2004

Contribution of Major Lifestyle Risk Factors for Incident Heart Failure in Older Adults: The Cardiovascular Health Study

scientific article

Control of blood pressure and risk of stroke among pharmacologically treated hypertensive patients

scientific article published on 01 February 2000

Coronary Artery Calcium to Guide a Personalized Risk-Based Approach to Initiation and Intensification of Antihypertensive Therapy.

scientific article published on 23 November 2016

Coronary Heart Disease Genetic Risk Score Predicts Cardiovascular Disease Risk in Men, Not Women

scientific article published on 01 October 2018

Coronary artery calcium in relation to initiation and continuation of cardiovascular preventive medications: The Multi-Ethnic Study of Atherosclerosis (MESA)

scientific article

Coronary risk assessment among intermediate risk patients using a clinical and biomarker based algorithm developed and validated in two population cohorts

scientific article (publication date: November 2012)

Correction: Four Novel Loci (19q13, 6q24, 12q24, and 5q14) Influence the Microcirculation In Vivo.

scientific article

Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

scientific article

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

scientific article published on 21 October 2019

Corrections to the nifedipine meta-analysis

scientific article published on 01 April 1996

Correlates and prevalence of benzodiazepine use in community-dwelling elderly

scientific article

Correlates of QT prolongation in older adults (the Cardiovascular Health Study). Cardiovascular Health Study Collaborative Research Group

scientific article published on 01 May 1994

Correlates of antithrombin, protein C, protein S, and TFPI in a healthy elderly cohort

scientific article published on 01 July 1998

Correlates of thrombin markers in an elderly cohort free of clinical cardiovascular disease

scientific article published on 01 September 1996

Cost-minimization and the number needed to treat in uncomplicated hypertension

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Cross-sectional association of endogenous steroid hormone, sex hormone-binding globulin, and precursor steroid levels with hemostatic factor levels in postmenopausal women

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Cystatin C and prognosis for cardiovascular and kidney outcomes in elderly persons without chronic kidney disease

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Cystatin C and sudden cardiac death risk in the elderly

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Cystatin C concentration as a predictor of systolic and diastolic heart failure

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Cystatin C concentration as a risk factor for heart failure in older adults

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Cystatin-C and inflammatory markers in the ambulatory elderly.

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Cystatin-C and mortality in elderly persons with heart failure.

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DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

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Defining and improving survival rates from cardiac arrest in US communities

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Diabetes in older adults: comparison of 1997 American Diabetes Association classification of diabetes mellitus with 1985 WHO classification.

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Diabetes mellitus, glycemic control, and risk of atrial fibrillation

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Directional dominance on stature and cognition in diverse human populations

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Discovering novel risk factors for venous thrombosis: a candidate-gene approach

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Discovery and fine mapping of serum protein loci through transethnic meta-analysis

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Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

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Discovery and refinement of loci associated with lipid levels

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Discovery and replication of several loci significantly associated with lean body mass: a large meta-analysis of genome wide association studies (GWAS) from the 'charge' and 'gefos' consortia

Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure

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Discovery of novel heart rate-associated loci using the Exome Chip

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Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

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Disentangling the genetics of lean mass

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Drug therapies for the primary prevention of cardiovascular events: trials and errors: 2009 Ancel Keys Memorial Lecture

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Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium

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Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

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Ectopy on a Single 12-Lead ECG, Incident Cardiac Myopathy, and Death in the Community

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Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies

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Epigenetic Signatures of Cigarette Smoking

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Esterified estrogen and conjugated equine estrogen and the risk of incident myocardial infarction and stroke

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Esterified estrogens and conjugated equine estrogens and the risk of venous thrombosis

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Estimating ethnic differences in self-reported new use of antidepressant medications: results from the Multi-Ethnic Study of Atherosclerosis.

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Exome Chip Analysis Identifies Low-Frequency a on Brain Magnetic Imaging

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Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

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Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

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ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

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Fibroblast Growth Factor 23, Mineral Metabolism, and Adiposity in Normal Kidney Function

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Fifteen Genetic Loci Associated With the Electrocardiographic P Wave

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Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

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Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans

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Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo

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Functional status is a confounder of the association of influenza vaccine and risk of all cause mortality in seniors

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GATM locus does not replicate in rhabdomyolysis study.

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GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium

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GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

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GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy

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Gene expression in thiazide diuretic or statin users in relation to incident type 2 diabetes

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Gene variants associated with ischemic stroke: the cardiovascular health study

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Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

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Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations

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Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

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Gene-gene Interaction Analyses for Atrial Fibrillation

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Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

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Generalized estimating equations for genome-wide association studies using longitudinal phenotype data.

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Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

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Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

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Genetic Determinants of Electrocardiographic P-wave Duration and Relation to Atrial Fibrillation

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Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium

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Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals

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Genetic Risk Prediction of Atrial Fibrillation

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Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

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Genetic Variants Associated with Circulating Fibroblast Growth Factor 23

Genetic Variants Associated with Circulating Parathyroid Hormone

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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

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Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Genetic architecture of subcortical brain structures in 38,851 individuals

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Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

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Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).

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Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

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Genetic diversity is a predictor of mortality in humans

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Genetic evidence of assortative mating in humans

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Genetic insights into biological mechanisms governing human ovarian ageing

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Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

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Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

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Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium

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Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

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Genetic loci for retinal arteriolar microcirculation

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Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

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Genetic predictors of fibrin D-dimer levels in healthy adults

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Genetic predictors of medically refractory ulcerative colitis

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Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies

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Genetic variability within the cholesterol lowering pathway and the effectiveness of statins in reducing the risk of MI

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Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes

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Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data

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Genetic variants in RBFOX3 are associated with sleep latency

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Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

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Genetic variants of coagulation factor XIII, postmenopausal estrogen therapy, and risk of nonfatal myocardial infarction

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Genetic variants of platelet glycoprotein receptors and risk of stroke in young women

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Genetic variants related to height and risk of atrial fibrillation: the cardiovascular health study

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Genetic variation associated with circulating monocyte count in the eMERGE Network

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Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis

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Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

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Genetic variation in the renin--angiotensin system, use of renin--angiotensin system inhibitors and the risk of myocardial infarction

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Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

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Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations

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Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study

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Genetically elevated fetuin-A levels, fasting glucose levels, and risk of type 2 diabetes: the cardiovascular health study

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Genetics and genomics for the prevention and treatment of cardiovascular disease: update: a scientific statement from the American Heart Association

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Genetics of coronary artery calcification among African Americans, a meta-analysis

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Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

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Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

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Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke

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Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium

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Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group

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Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

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Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent

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Genome-wide Meta-analysis of 158,000 Individuals of European Ancestry Identifies Three Loci Associated with Chronic Back Pain

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

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Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

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Genome-wide analysis of genetic loci associated with Alzheimer disease

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Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation

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Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia

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Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

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Genome-wide association analysis identifies multiple loci related to resting heart rate

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Genome-wide association analysis identifies six new loci associated with forced vital capacity

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Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM

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Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

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Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

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Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology

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Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

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Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium.

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Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts.

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Genome-wide association of body fat distribution in African ancestry populations suggests new loci

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Genome-wide association studies and large-scale collaborations in epidemiology

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Genome-wide association studies identify genetic loci for low von Willebrand factor levels

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Genome-wide association studies identify genetic loci for low von Willebrand factor levels

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Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium

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Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium

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Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels

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Genome-wide association study and meta-analysis identify loci associated with ventricular and supraventricular ectopy.

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Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

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Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction

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Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest

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Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology [...]

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Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

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Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

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Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine

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Genome-wide association study of PR interval

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Genome-wide association study of blood pressure and hypertension

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Genome-wide association study of breakfast skipping links clock regulation with food timing

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Genome-wide association study of cardiac structure and systolic function in African Americans: the Candidate Gene Association Resource (CARe) study

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Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project

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Genome-wide association study of retinopathy in individuals without diabetes

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Genome-wide gene-environment interactions on quantitative traits using family data

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Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

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Genome-wide meta-analyses of smoking behaviors in African Americans

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Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

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Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

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Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

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Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain

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Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

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Genome-wide meta-analysis of SNP and antihypertensive medication interactions on left ventricular traits in African Americans

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Genome-wide meta-analysis of SNP-by9-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry

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Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry

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Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans

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Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD.

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Genomewide Association Study of Statin-Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink

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Genomewide association studies of stroke

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Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits

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Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism

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Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium

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Genomics and medicine: distraction, incremental progress, or the dawn of a new age?

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Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

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Glucose, blood pressure, and lipid control in older people with and without diabetes mellitus: the Cardiovascular Health Study

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Glucose, insulin, and incident hypertension in the multi-ethnic study of atherosclerosis

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HMG CoA reductase inhibitors and the risk of venous thrombosis among postmenopausal women

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Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

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Health and Functional Status of Adults Aged 90 Years in the United States

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Heterogeneous Exposure Associations in Observational Cohort Studies: The Example of Blood Pressure in Older Adults

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IL-6 gene variation is associated with IL-6 and C-reactive protein levels but not cardiovascular outcomes in the Cardiovascular Health Study

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Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals

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Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

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Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease

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Identifying genetic loci associated with antidepressant drug response with drug-gene interaction models in a population-based study

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Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program

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Inflammation biomarkers and near-term death in older men.

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Influenza vaccination and the risk of primary cardiac arrest

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Influenza vaccination is not associated with a reduction in the risk of recurrent coronary events

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Inhaled beta-2 adrenergic receptor agonists and primary cardiac arrest

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Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

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Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

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Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

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Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

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Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

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Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors

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Multiple loci are associated with white blood cell phenotypes

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Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

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NT -pro BNP as a Mediator of the Racial Difference in Incident Atrial Fibrillation and Heart Failure

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New insights into the genetic etiology of Alzheimer's disease and related dementias

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Nifedipine. Dose-related increase in mortality in patients with coronary heart disease

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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies

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Norplant implants and cardiovascular disease

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Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

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Novel Genetic Loci Associated With Retinal Microvascular Diameter

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Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium

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Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

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Novel genetic loci associated with hippocampal volume

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Novel genetic loci underlying human intracranial volume identified through genome-wide association

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Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

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Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts

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Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study

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Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

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Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association

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Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

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Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

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Rare coding variants pinpoint genes that control human hematological traits

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Roger et al. respond to "future of population studies"

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Role of Coronary Artery and Thoracic Aortic Calcium as Risk Modifiers to Guide Antihypertensive Therapy in Stage 1 Hypertension (From the Multiethnic Study of Atherosclerosis)

scientific article published on 14 March 2020

Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

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Rooted in risk: genetic predisposition for low-density lipoprotein cholesterol level associates with diminished low-density lipoprotein cholesterol response to statin treatment

scientific article published on 20 September 2016

Rosiglitazone and cardiovascular risk

scientific article published on 21 May 2007

SHARE: an adaptive algorithm to select the most informative set of SNPs for candidate genetic association

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SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

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Sampling Elderly in the Community: A Comparison of Commercial Telemarketing Lists and Random Digit Dialing Techniques for Assessing Health Behaviors and Health Status

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Seasonal variation in 25-hydroxyvitamin D concentrations in the cardiovascular health study

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Separate prediction of intracerebral hemorrhage and ischemic stroke

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Sequence analysis of six blood pressure candidate regions in 4,178 individuals: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study

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Sequencing Analysis at 8p23 Identifies Multiple Rare Variants in DLC1 Associated with Sleep-Related Oxyhemoglobin Saturation Level

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Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

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Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

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Serial Plasma Phospholipid Fatty Acids in the De Novo Lipogenesis Pathway and Total Mortality, Cause-Specific Mortality, and Cardiovascular Diseases in the Cardiovascular Health Study

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Serum amyloid P and cardiovascular disease in older men and women: results from the Cardiovascular Health Study.

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Serum homocysteine, thermolabile variant of methylene tetrahydrofolate reductase (MTHFR), and venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology (LITE).

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Serum lipid levels and the risk of venous thrombosis

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Serum potassium and stroke risk among treated hypertensive adults

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Serum potassium level and dietary potassium intake as risk factors for stroke

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Sex-Specific Associations of Cardiovascular Risk Factors and Biomarkers With Incident Heart Failure

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Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants

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Short-term and long-term risk of incident ischemic stroke after transient ischemic attack

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Should dihydropyridines be used as first-line drugs in the treatment of hypertension? The con side

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Should ethnicity serve as the basis for clinical trial design? Diversity and inclusiveness should remain the guiding principles for clinical trials

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Should evidence-based proof of drug efficacy be extrapolated to a "class of agents"?

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Simple estimates of haplotype relative risks in case-control data

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Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

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Sleep characteristics that predict atrial fibrillation

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Smoking status and risk for recurrent coronary events after myocardial infarction.

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Smoking, postmenopausal hormone therapy and the risk of venous thrombosis: a population-based, case-control study

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Soluble CD14 and Risk of Heart Failure and its Subtypes in Older Adults

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Soluble Inflammatory Markers and Risk of Incident Fractures in Older Adults: The Cardiovascular Health Study

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Soluble ST2 for Prediction of Heart Failure and Cardiovascular Death in an Elderly, Community-Dwelling Population

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Soluble intracellular adhesion molecule-1 is associated with cardiovascular disease risk and mortality in older adults

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Stages of systemic hypertension and blood pressure as correlates of computed tomography-assessed aortic valve calcium (from the Multi-Ethnic Study of Atherosclerosis)

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Statin Use and the Risk of Incident Dementia

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Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study

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Statins and intracerebral hemorrhage: collaborative systematic review and meta-analysis.

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Stopping medical research to save money: a broken pact with researchers and patients

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Straight talk from... Bruce Psaty. Interviewed by Emma Marris

scientific article published on 29 June 2007

Strategic transformation of population studies: recommendations of the working group on epidemiology and population sciences from the National Heart, Lung, and Blood Advisory Council and Board of External Experts

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Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

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Structural and functional vascular alterations and incident hypertension in normotensive adults: the Multi-Ethnic Study of Atherosclerosis

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Stuck in a Bind With Phosphate Binders

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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

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Study of Cardiovascular Health Outcomes in the Era of Claims Data: The Cardiovascular Health Study

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Subclinical Disease as an Independent Risk Factor for Cardiovascular Disease

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Subclinical vascular disease burden and risk for death and cardiovascular events in older community dwellers

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Suboptimal nutritional intake for hypertension control in 4 ethnic groups

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Sudden death and myocardial infarction in first degree relatives as predictors of primary cardiac arrest

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Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis

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Surrogate end points and FDA approval: a tale of 2 lipid-altering drugs

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Surrogate end points, health outcomes, and the drug-approval process for the treatment of risk factors for cardiovascular disease

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Surveillance and ascertainment of cardiovascular events. The Cardiovascular Health Study

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Survival associated with two sets of diagnostic criteria for congestive heart failure

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Systematic identification of trans eQTLs as putative drivers of known disease associations

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Systematically missing confounders in individual participant data meta-analysis of observational cohort studies

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Systolic and diastolic blood pressure, incident cardiovascular events, and death in elderly persons: the role of functional limitation in the Cardiovascular Health Study

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Systolic blood pressure and incident heart failure in the elderly. The Cardiovascular Health Study and the Health, Ageing and Body Composition Study

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T-helper type 1 bias in healthy people is associated with cytomegalovirus serology and atherosclerosis: the Multi-Ethnic Study of Atherosclerosis

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TRAJECTORIES OF CARDIOVASCULAR RISK FACTORS AND HEALTHY LONGEVITY: THE CARDIOVASCULAR HEALTH STUDY

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Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

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Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study

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Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study

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Telomere length and the risk of atrial fibrillation: insights into the role of biological versus chronological aging

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Telomere-associated polymorphisms correlate with cardiovascular disease mortality in Caucasian women: the Cardiovascular Health Study

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Temporal Trends in the Incidence of and Mortality Associated With Heart Failure With Preserved and Reduced Ejection Fraction

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Temporal patterns in the medical treatment of congestive heart failure with angiotensin-converting enzyme inhibitors in older adults, 1989 through 1995.

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Temporal patterns of antihypertensive medication use among elderly patients. The Cardiovascular Health Study

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Temporal patterns of antihypertensive medication use among older adults, 1989 through 1992. An effect of the major clinical trials on clinical practice?

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Temporal trends in the use of anticoagulants among older adults with atrial fibrillation

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The Alzheimer's Disease Sequencing Project: Study design and sample selection

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The Application of Genomics in Diabetes: Barriers to Discovery and Implementation

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The Association Between IGF-I and IGFBP-3 and Incident Diabetes in an Older Population of Men and Women in the Cardiovascular Health Study

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The Association of Obesity and Cardiometabolic Traits With Incident HFpEF and HFrEF

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The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium as a model of collaborative science

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The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases

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The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

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The Kaiser Family Foundation Community Health Promotion Grants Program: findings from an outcome evaluation

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The Kozak sequence polymorphism of platelet glycoprotein Ibalpha and risk of nonfatal myocardial infarction and nonfatal stroke in young women

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The Messenger under Attack — Intimidation of Researchers by Special-Interest Groups

The PROGRESS trial: questions about the effectiveness of angiotensin converting enzyme inhibitors. Perindopril pROtection aGainst REcurrent Stroke Study

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The Polygenic and Monogenic Basis of Blood Traits and Diseases

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The Relation Between Thyroid Function and Anemia: A Pooled Analysis of Individual Participant Data

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The Relation of Serum Potassium Concentration with Cardiovascular Events and Mortality in Community-Living Individuals

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The Risk of Myocardial Infarction Associated With Antihypertensive Drug Therapies

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The aging and dying processes and the health of older adults

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The association between lipid levels and the risks of incident myocardial infarction, stroke, and total mortality: The Cardiovascular Health Study

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The association between time since last meal and blood pressure in older adults: the cardiovascular health study

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The association of F11 genetic variants with the risk of incident venous thrombosis among women, by statin use.

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The association of PAI-1 promoter 4G/5G insertion/deletion polymorphism with myocardial infarction and stroke in young women

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The association of antihypertensive agents with MRI white matter findings and with Modified Mini-Mental State Examination in older adults

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The association of antihypertensive medication with serum creatinine changes in older adults

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The association of microalbuminuria with clinical cardiovascular disease and subclinical atherosclerosis in the elderly: the Cardiovascular Health Study

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The association of smoking with venous thrombosis in women. A population-based, case-control study

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The association of statin therapy with the risk of recurrent venous thrombosis

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The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels

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The contribution of a 9p21.3 variant, a KIF6 variant, and C-reactive protein to predicting risk of myocardial infarction in a prospective study

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The differential association of conjugated equine estrogen and esterified estrogen with activated protein C resistance in postmenopausal women.

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The distribution of coagulation factors VII and VIII and fibrinogen in adults over 65 years. Results from the Cardiovascular Health Study

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The evaluation of the Henry J. Kaiser Family Foundation's Community Health Promotion Grant Program: design

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The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

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The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE)

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The medical cost of undiagnosed sleep apnea

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The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes: response to Kahn et al

The potential costs of upcoding for heart failure in the United States

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The potential risks of expedited approval of drugs for acute bacterial infections

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The presence of frailty in elderly persons with chronic renal insufficiency

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The record on rosiglitazone and the risk of myocardial infarction

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The relationship between exercise and risk of venous thrombosis in elderly people

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The relative risk of incident coronary heart disease associated with recently stopping the use of beta-blockers

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The relative risk of myocardial infarction in patients who have high blood pressure and non-cardiac pain

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The reliability of medication inventory methods compared to serum levels of cardiovascular drugs in the elderly.

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The risk of myocardial infarction associated with inhaled beta-adrenoceptor agonists

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The risk of myocardial infarction associated with the combined use of estrogens and progestins in postmenopausal women

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The role of functional status on the relationship between blood pressure and cognitive decline: the Cardiovascular Health Study

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The transcriptional landscape of age in human peripheral blood

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The unnecessary controversy

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Therapeutic benefits of ACE inhibitors and other antihypertensive drugs in patients with type 2 diabetes

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Therapy with hydroxymethylglutaryl coenzyme a reductase inhibitors (statins) and associated risk of incident cardiovascular events in older adults: evidence from the Cardiovascular Health Study

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Thrombosis in the young: effect of atherosclerotic risk factors on the risk of myocardial infarction associated with prothrombotic factors

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Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis

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Thyroid function in the euthyroid range and adverse outcomes in older adults

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Thyroid function within the normal range and risk of coronary heart disease: an individual participant data analysis of 14 cohorts

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Time Trends in the Use of Cholesterol-Lowering Agents in Older Adults

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Time to act on drug safety

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Time trends in high blood pressure control and the use of antihypertensive medications in older adults: the Cardiovascular Health Study

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Time trends in the use of anti-hypertensive medications: results from the Multi-Ethnic Study of Atherosclerosis.

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Time trends in the use of beta-blockers and other pharmacotherapies in older adults with congestive heart failure

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Total and cause-specific mortality in the cardiovascular health study

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Total insulinlike growth factor 1 and insulinlike growth factor binding protein levels, functional status, and mortality in older adults

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Traditional risk factors and subclinical disease measures as predictors of first myocardial infarction in older adults: the Cardiovascular Health Study.

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Trajectories of Nonagenarian Health: Gender, Age, and Period Effects

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Trans-ethnic Evaluation Identifies Novel Low Frequency Loci Associated with 25-Hydroxyvitamin D Concentrations.

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Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

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Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

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Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

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Trans-ethnic meta-analysis of white blood cell phenotypes

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Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study

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Transforming growth factor beta-1 and incidence of heart failure in older adults: the Cardiovascular Health Study

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Treatment of hypertensive patients with diabetes

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Trends in pharmacologic management of hypertension in the United States

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Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium

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Trends in the post-hospitalization medical treatment of unstable angina pectoris: 1990 to 1995.

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Universal screening and drug treatment of dyslipidemia in children and adolescents

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Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

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Use of Electronic Health Data to Estimate Heart Failure Events in a Population-Based Cohort with CKD.

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Use of Factor V Leiden genetic testing in practice and impact on management

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Use of Repeated Blood Pressure and Cholesterol Measurements to Improve Cardiovascular Disease Risk Prediction: An Individual-Participant-Data Meta-Analysis

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Use of administrative data to estimate the incidence of statin-related rhabdomyolysis

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Use of alendronate and risk of incident atrial fibrillation in women

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Use of calcium channel blockers and risk of hospitalized gastrointestinal tract bleeding

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Use of diuretics and other antihypertensive medications in relation to the risk of renal cell cancer

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Use of low-dose oral contraceptives and stroke in young women

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Use of sonography to evaluate carotid atherosclerosis in the elderly. The Cardiovascular Health Study. CHS Collaborative Research Group

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Use of statins and antihypertensive medications in relation to risk of long-standing persistent atrial fibrillation

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Usefulness of myeloperoxidase levels in healthy elderly subjects to predict risk of developing heart failure

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Using built environment characteristics to predict walking for exercise

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Utility of Nontraditional Risk Markers in Atherosclerotic Cardiovascular Disease Risk Assessment

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Utility of Nontraditional Risk Markers in Individuals Ineligible for Statin Therapy According to the 2013 American College of Cardiology/American Heart Association Cholesterol Guidelines.

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Validation of an atrial fibrillation risk algorithm in whites and African Americans

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Validation of the health ABC heart failure model for incident heart failure risk prediction: the Cardiovascular Health Study

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Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry

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Variation in 24 hemostatic genes and associations with non-fatal myocardial infarction and ischemic stroke

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Variation in eicosanoid genes, non-fatal myocardial infarction and ischemic stroke

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Variation in event rates in trials of patients with type 2 diabetes

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Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke

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Variation in resting heart rate over 4 years and the risks of myocardial infarction and death among older adults

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Vascular events, mortality, and preventive therapy following ischemic stroke in the elderly

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Ventricular Ectopy as a Predictor of Heart Failure and Death

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Visit-to-Visit Blood Pressure Variability and Mortality and Cardiovascular Outcomes Among Older Adults: The Health, Aging, and Body Composition Study

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Vitamin D, parathyroid hormone, and sudden cardiac death: results from the Cardiovascular Health Study

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Walking speed and risk of incident ischemic stroke among postmenopausal women

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Weight loss, muscle strength, and angiotensin-converting enzyme inhibitors in older adults with congestive heart failure or hypertension

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When Can Intermediate Outcomes Be Used as Surrogate Outcomes?

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When you look for evidence and find too much: systematic reviews to the rescue

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White Matter Lesion Progression: Genome-Wide Search for Genetic Influences

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Whole Exome Sequencing in Atrial Fibrillation

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Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

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Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium

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Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants

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Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

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Whole-Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized With Early-Onset Myocardial Infarction

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Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

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Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program

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Whole-genome sequence-based analysis of high-density lipoprotein cholesterol

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Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program

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Willingness to pay for antihypertensive care: evidence from a staff-model HMO.

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Yield and consistency of arrhythmia detection with patch electrocardiographic monitoring: The Multi-Ethnic Study of Atherosclerosis

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beta(2)-Adrenergic receptor polymorphisms and determinants of cardiovascular risk: the Cardiovascular Health Study

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beta1- and beta2-adrenergic receptor gene variation, beta-blocker use and risk of myocardial infarction and stroke

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