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List of works by Orla Hardiman

"I hate being a burden": The patient perspective on carer burden in amyotrophic lateral sclerosis

scientific article published on 9 February 2016

50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis

article

?True? sporadic ALS associated with a novel SOD-1 mutation

article by Michael D. Alexander et al published 24 October 2002 in Annals of Neurology

A 45-year history of acquired autoimmune neuromyotonia

scientific article published on 22 September 2006

A Double-Blind Randomised Placebo-Controlled Evaluation of Three Doses of Botulinum Toxin Type A (Dysport ® ) in the Treatment of Spastic Equinovarus Deformity after Stroke

scientific article published on 01 January 2003

A case of stiff-person syndrome, type 1 diabetes, celiac disease and dermatitis herpetiformis

scientific article published on 15 January 2009

A case-control study of hormonal exposures as etiologic factors for ALS in women: Euro-MOTOR.

scientific article

A genetic overview of Atlantic coastal populations from Europe and North-West Africa based on a 17 X-STR panel

scientific article

A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis

scientific article

A genome-wide association study of sporadic ALS in a homogenous Irish population

scientific article published on 5 December 2007

A large genome scan for rare CNVs in amyotrophic lateral sclerosis

scientific article

A large-scale international meta-analysis of paraoxonase gene polymorphisms in sporadic ALS

scientific article published on 25 March 2009

A mapping review of international guidance on the management and care of amyotrophic lateral sclerosis (ALS).

scientific article published on 14 April 2016

A multidisciplinary clinic approach improves survival in ALS: a comparative study of ALS in Ireland and Northern Ireland

scientific article published on 30 December 2014

A novel MYH7 Leu1453pro mutation resulting in Laing distal myopathy in an Irish family

scientific article published on 28 September 2014

A novel candidate region for ALS on chromosome 14q11.2.

scientific article published in November 2004

A novel mutation as a cause of L-2-hydroxyglutaric aciduria.

scientific article published on 27 April 2009

A population-based epidemiologic study of adult neuromuscular disease in the Republic of Ireland

scientific article published on 7 December 2016

A revision of the El Escorial criteria - 2015.

scientific article

ALS Untangled No. 20: the Deanna protocol

scientific article published on 02 May 2013

ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)

scientific article

ALS untangled No. 17: "when ALS is lyme".

scientific article

ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function

scientific article published on 25 June 2018

ALS-specific cognitive and behavior changes associated with advancing disease stage in ALS

scientific article published on 12 September 2018

ALSUntangled (ALSU): A Scientific Approach to Off-Label Treatment Options for People with ALS Using Tweets and Twitters

article

ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis

scientific article published on 26 February 2006

ATXN1 repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization

scientific article published on 19 May 2020

Absence of consensus in diagnostic criteria for familial neurodegenerative diseases

scientific article published on 01 April 2012

Acceptance and decision making in amyotrophic lateral sclerosis from a life-course perspective

scientific article published on 13 December 2013

Access to health services in Ireland for people with Multiple Sclerosis and Motor Neurone Disease

article

Adenylyl cyclase activity in clonally derived human myoblast cultures: evidence for myoblast heterogeneity

scientific article

Age at onset of amyotrophic lateral sclerosis is proportional to life expectancy

Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

scientific article

Age-period-cohort analysis of trends in amyotrophic lateral sclerosis incidence ⬇️

scientific article published on 2 July 2016

Aggregation of neurodegenerative disease in ALS kindreds

scientific article published on April 2009

Aggregation of neurologic and neuropsychiatric disease in amyotrophic lateral sclerosis kindreds: a population-based case-control cohort study of familial and sporadic amyotrophic lateral sclerosis

scientific article published on 10 September 2013

Amyotrophic Lateral Sclerosis Mimic Syndromes

scientific article published on 01 January 2000

Amyotrophic Lateral Sclerosis: Enteral Nutrition Provision—Endoscopic or Radiologic Gastrostomy?

scientific article published on 01 September 2002

Amyotrophic lateral sclerosis

scientific article published in The Lancet

Amyotrophic lateral sclerosis

scientific article published on 25 May 2017

Amyotrophic lateral sclerosis

scientific article published on 05 October 2017

Amyotrophic lateral sclerosis and soccer: A different epidemiological approach strengthen the previous findings

scientific article published on 08 November 2007

Amyotrophic lateral sclerosis and vascular risk: a metabolic conundrum

scientific article published on 01 June 2011

Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms

scientific article

Amyotrophic lateral sclerosis, physical exercise, trauma and sports: results of a population-based pilot case-control study

scientific article

Amyotrophic lateral sclerosis: moving towards a new classification system

scientific article published on October 2016

An all-Ireland epidemiological study of MND, 2004-2005

scientific article published on 01 January 2009

An exploratory spatial analysis of ALS incidence in Ireland over 17.5 years (1995-July 2013).

scientific article

An outcome study of riluzole in amyotrophic lateral sclerosis--a population-based study in Ireland, 1996-2000.

scientific article published in April 2003

Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD

scientific article

Analysis of amyotrophic lateral sclerosis as a multistep process: a population-based modelling study

scientific article

Analysis of genome-wide copy number variation in Irish and Dutch ALS populations

scientific article published on 7 August 2008

Analysis of the KIFAP3 gene in amyotrophic lateral sclerosis: a multicenter survival study

scientific article

Analysis of the hexanucleotide repeat expansion and founder haplotype at C9ORF72 in an Irish psychosis case-control sample

scientific article

Analysis ofFGGYas a risk factor for sporadic amyotrophic lateral sclerosis

article

Andersen–Tawil Syndrome With Early Fixed Myopathy

scientific article published on 01 December 2014

Angiogenin levels and ANG genotypes: dysregulation in amyotrophic lateral sclerosis

scientific article

Anti-NMDA receptor encephalitis: an important differential diagnosis in psychosis

scientific article published on 7 October 2011

Assessing behavioural changes in ALS: cross-validation of ALS-specific measures

scientific article

Assessing individual quality of life in amyotrophic lateral sclerosis

scientific article published in January 2001

Assessment of subjective and motor fatigue in Polio survivors, attending a Postpolio clinic, comparison with healthy controls and an exploration of clinical correlates.

scientific article published on 16 December 2013

Association between alcohol exposure and the risk of amyotrophic lateral sclerosis in the Euro-MOTOR study

Association of NIPA1 repeat expansions with amyotrophic lateral sclerosis in a large international cohort

scientific article published on 22 September 2018

Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis

scientific article published on 31 May 2016

Association of the H63D polymorphism in the hemochromatosis gene with sporadic ALS

article

Associations of Electric Shock and Extremely Low-Frequency Magnetic Field Exposure With the Risk of Amyotrophic Lateral Sclerosis

scientific article published on 01 April 2019

Ataxin-2 expands insight into the ALS clinical spectrum

scientific article published on 19 December 2014

Atypical social cognitive processing in premotor Huntington’s disease: a single case study

scientific article published on 01 March 2017

Basal ganglia involvement in amyotrophic lateral sclerosis

scientific article

Benefits, pitfalls, and future design of population-based registers in neurodegenerative disease.

scientific article

Binding of 125I-insulin-like growth factor-II to cells cultured in fetal bovine serum: a complication

scientific article

Blink rate in ALS

Boosting controlled autoimmunity: a new therapeutic target for CNS disorders

scientific article published on May 2008

Building a supportive framework for brain research in Ireland: Inaugural position paper of the Irish Brain Council

scientific article published on 19 February 2019

C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis

scientific article

C9orf72 expansion differentially affects males with spinal onset amyotrophic lateral sclerosis

scientific article published on 23 September 2016

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia

scientific article published on 15 April 2016

Caregiver burden in amyotrophic lateral sclerosis: a cross-sectional investigation of predictors

scientific article published on 23 April 2015

Caregivers of patients with amyotrophic lateral sclerosis: investigating quality of life, caregiver burden, service engagement, and patient survival

scientific article

Caregiving in ALS - a mixed methods approach to the study of Burden

scientific article

Central 5-HT receptor hypersensitivity in migraine without aura.

scientific article published in February 2003

Characteristic Increases in EEG Connectivity Correlate With Changes of Structural MRI in Amyotrophic Lateral Sclerosis.

scientific article published on 9 November 2017

Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study

scientific article published on October 2010

Chronic ataxic neuropathy with cold agglutinins: Atypical phenotype and response to anti-CD20 antibodies

scientific article published on 01 November 2003

Circulating insulin-like growth factors and related binding proteins are selectively altered in amyotrophic lateral sclerosis and multiple sclerosis

scientific article published on 13 August 2007

Clinical diagnosis and management of amyotrophic lateral sclerosis

scientific article published on 11 October 2011

Clinical features of amyotrophic lateral sclerosis according to the El Escorial and Airlie House diagnostic criteria: A population-based study

scientific article published in August 2000

Clustering of Neuropsychiatric Disease in First-Degree and Second-Degree Relatives of Patients With Amyotrophic Lateral Sclerosis

scientific article published on 16 October 2017

Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study

scientific article published on 3 February 2012

Cognitive changes predict functional decline in ALS: a population-based longitudinal study

scientific article

Cognitive impairment in amyotrophic lateral sclerosis

scientific article

Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

preprint

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

scholarly article

Comparison of the clinical and genetic features of amyotrophic lateral sclerosis across Cuban, Uruguayan and Irish clinic-based populations

scientific article published on 07 March 2019

Computerized databases for ALS incidence calculations: ready, steady, but don't go yet.

scientific article

Connectivity-based characterisation of subcortical grey matter pathology in frontotemporal dementia and ALS: a multimodal neuroimaging study.

scientific article published on 8 February 2018

Control of motoneuron survival by angiogenin.

scientific article

Controversies and priorities in amyotrophic lateral sclerosis

scientific article

Critical issues in ALS case-control studies: the case of the Euro-MOTOR study

scientific article published on 10 February 2017

Crowdsourced analysis of clinical trial data to predict amyotrophic lateral sclerosis progression

scientific article

Current pathways for epidemiological research in amyotrophic lateral sclerosis

scientific article

Delineating the genetic heterogeneity of ALS using targeted high-throughput sequencing

scientific article published on 23 July 2013

Descriptive epidemiology of amyotrophic lateral sclerosis: new evidence and unsolved issues

scientific article published on January 2008

Detection of long repeat expansions from PCR-free whole-genome sequence data

scientific article

Detection rates of sexual dysfunction amongst patients with multiple sclerosis in an outpatient setting--can this be improved?

scientific article published on November 2006

Determining the incidence of familiality in ALS: A study of temporal trends in Ireland from 1994 to 2016.

scientific article

Development of an Automated MRI-Based Diagnostic Protocol for Amyotrophic Lateral Sclerosis Using Disease-Specific Pathognomonic Features: A Quantitative Disease-State Classification Study

scientific article

Dexpramipexole versus placebo for patients with amyotrophic lateral sclerosis (EMPOWER): a randomised, double-blind, phase 3 trial

scientific article published on 23 September 2013

Differential glucocorticoid effects on the fusion of Duchenne/Becker and control muscle cultures: Pharmacologic detection of accelerated aging in dystrophic muscle

article

Differing central amine receptor sensitivity in different migraine subtypes? A neuroendocrine study using buspirone

scientific article published in February 2003

Direct effects of cyclosporin A and cyclophosphamide on differentiation of normal human myoblasts in culture

article

Discordant performance on the 'Reading the Mind in the Eyes' Test, based on disease onset in amyotrophic lateral sclerosis

scientific article published on 6 May 2016

Dysfunction of attention switching networks in amyotrophic lateral sclerosis

scientific article published on 02 February 2019

Dystrophin deficiency, altered cell signalling and fibre hypertrophy

scientific article published on July 1994

ECAS A-B-C: alternate forms of the Edinburgh Cognitive and Behavioural ALS Screen

scientific article published on 5 December 2017

EFNS guidelines on the clinical management of amyotrophic lateral sclerosis (MALS)--revised report of an EFNS task force

scientific article published on 14 September 2011

EFNS task force on management of amyotrophic lateral sclerosis: guidelines for diagnosing and clinical care of patients and relatives

scientific article published in December 2005

EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans

scientific article published in September 2012

ETHNIC VARIATION IN THE INCIDENCE OF ALS: A SYSTEMATIC REVIEW

article

Edaravone: a new treatment for ALS on the horizon?

scientific article published on 15 May 2017

Effect modification of the association between total cigarette smoking and ALS risk by intensity, duration and time-since-quitting: Euro-MOTOR

scientific article published on 21 August 2019

Effect of a multidisciplinary amyotrophic lateral sclerosis (ALS) clinic on ALS survival: a population based study, 1996-2000.

scientific article

Effect of referral bias on assessing survival in als.

scientific article published in August 2007

Elevated serum angiogenin levels in ALS.

scientific article published in November 2006

End-of-life management in patients with amyotrophic lateral sclerosis

scientific article

Epidemiology and clinical features of amyotrophic lateral sclerosis in Ireland between 1995 and 2004.

scientific article published on 18 July 2007

Equivalency and practice effects of alternative versions of the Edinburgh Cognitive and Behavioral ALS Screen (ECAS)

scientific article published on 13 December 2019

Erratum to: Caregiver burden in amyotrophic lateral sclerosis: a cross-sectional investigation of predictors

scientific article published on 01 December 2015

Estimation of coherence using the median is robust against EEG artefacts

scientific article

Ethnic variation in the incidence of ALS: a systematic review

scientific article published on March 2007

Evaluation of stroke management in an Irish university teaching hospital: the Royal College of Physicians stroke audit package

scientific article published in July 2001

Evaluation of the Golgi trafficking protein VPS54 (wobbler) as a candidate for ALS.

scientific article

Evidence of reduced frequency of spinal muscular atrophy type I in the Cuban population

scientific article published in August 2005

Executive dysfunction is a negative prognostic indicator in patients with ALS without dementia

scientific article published in April 2011

Exerting control and adapting to loss in amyotrophic lateral sclerosis

scientific article

Exome array analysis of rare and low frequency variants in amyotrophic lateral sclerosis

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

scientific article published on 19 February 2015

Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS.

scientific article published on 22 October 2014

Experience of services as a key outcome in amyotrophic lateral sclerosis (ALS) care: the case for a better understanding of patient experiences

scientific article

Expression of major histocompatibility complex antigens in cultures of clonally derived human myoblasts

article

EyeBallGUI: A Tool For Visual Inspection And Binary Marking of Multi-Channel Bio-Signals

Factors associated with burden of primary headache in a specialty clinic

scientific article published in June 2003

Familial aggregation in amyotrophic lateral sclerosis

scientific article published on 01 April 2010

Fecundity in ALS

First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models

scientific article published on 30 September 2014

From first symptoms to diagnosis of amyotrophic lateral sclerosis: perspectives of an Irish informal caregiver cohort-a thematic analysis

scientific article published on 20 March 2017

From pneumomyelography to cord tractography: historical perspectives on spinal imaging

Functional Connectivity Changes in Resting-State EEG as Potential Biomarker for Amyotrophic Lateral Sclerosis

scientific article published on 19 June 2015

Generation of six induced pluripotent stem cell (iPSC) lines from two patients with amyotrophic lateral sclerosis (NUIGi043-A, NUIGi043-B, NUIGi043-C, NUIGi044-A, NUIGi044-B, NUIGi044-C)

scientific article published on 29 August 2019

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

scientific article published on 21 March 2017

Genetic effects influencing risk for major depressive disorder in China and Europe

scientific article

Genetic screening in sporadic ALS and FTD.

scientific article published on 22 June 2017

Genetic testing in ALS: A survey of current practices

scientific article

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

scientific article published in March 2018

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

scientific article published on 25 July 2016

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis

scientific article

Genomic signals of migration and continuity in Britain before the Anglo-Saxons

scientific article published on 19 January 2016

Geographical structure and differential natural selection among North European populations

scientific article published on 05 March 2009

Global burden of motor neuron diseases: mind the gaps

scientific article published on 05 November 2018

Good practice in the management of amyotrophic lateral sclerosis: clinical guidelines. An evidence-based review with good practice points. EALSC Working Group

scientific article published on August 2007

Grey matter correlates of clinical variables in amyotrophic lateral sclerosis (ALS): a neuroimaging study of ALS motor phenotype heterogeneity and cortical focality

scientific article

Group interventions for amyotrophic lateral sclerosis caregivers in Ireland: a randomised controlled trial protocol

scientific article published on 20 September 2019

H63D polymorphism in HFE is not associated with amyotrophic lateral sclerosis

scientific article published on 11 October 2012

Health and social care costs of managing amyotrophic lateral sclerosis (ALS): an Irish perspective

scientific article published on 06 October 2014

Heritability of Amyotrophic Lateral Sclerosis

scientific article published on 01 August 2015

Heterogeneity of presentation and outcome in the Irish rapid-onset dystonia-parkinsonism kindred

scientific article published on July 2007

High incidence of osteoporosis and fractures in an aging post-polio population

scientific article published on October 2009

Homozygosity mapping in an Irish ALS case-control cohort describes local demographic phenomena and points towards potential recessive risk loci

scientific article published on 23 January 2015

Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology

scientific article published on 01 December 2019

Huntington's disease presenting as amyotrophic lateral sclerosis

scientific article published in August 2010

Huntington's disease presenting as amyotrophic lateral sclerosis

Hyperuricemia in type V glycogenosis

scientific article published in April 1987

IGF-1 receptor mediates differentiation of primary cultures of mouse skeletal myoblasts

scientific article published in February 2003

Ibuprofen-induced aseptic meningoencephalitis

scientific article

Identifying behavioural changes in ALS: Validation of the Beaumont Behavioural Inventory (BBI).

scientific article published on 28 November 2016

Incidence and prevalence of ALS in Ireland, 1995-1997: a population-based study

scientific article published in February 1999

Incidence of amyotrophic lateral sclerosis in Europe

scientific article

Inflammatory myopathy in thyrotoxicosis

scientific article published on 01 February 1997

Insular Celtic population structure and genomic footprints of migration.

scientific article

Interictal spike localisation with methohexitone: preoperative activation and surgical follow-up

scientific article published in July 1987

Interictal spiking and seizures

Interictal spiking and seizures

scientific article published on 01 June 1986

Intermediate repeat expansion length in C9orf72 may be pathological in amyotrophic lateral sclerosis

scientific article published on 23 September 2013

Intracranial giant cell arteritis with fatal middle cerebral artery territory infarct.

scientific article published on July 2003

Irish neurological association

July 2017 ENCALS statement on edaravone

scientific article

Leptospire-induced acute rhabdomyolysis in a patient with previously undiagnosed mitochondrial myopathy

scientific article published on 01 September 2000

Lessons of ALS imaging: Pitfalls and future directions - A critical review

scientific article

Lifetime Risk and Heritability of Amyotrophic Lateral Sclerosis

scientific article published on 22 July 2019

Longitudinal analysis of sniff nasal inspiratory pressure assessed using occluded and un-occluded measurement techniques in amyotrophic lateral sclerosis and primary lateral sclerosis

scientific article published on 17 July 2019

Longitudinal predictors of caregiver burden in amyotrophic lateral sclerosis: a population-based cohort of patient-caregiver dyads

scientific article

Longitudinal structural changes in ALS: a three time-point imaging study of white and gray matter degeneration

scientific article published on 7 December 2017

Management of Amyotrophic Lateral Sclerosis

Management of respiratory symptoms in ALS ⬇️

scientific article published on November 17, 2010

Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS.

scientific article

Maximum Voluntary Isometric Contraction: Investigation of Reliability and Learning Effect

Maximum voluntary isometric contraction: Reference values and clinical application

Maximum voluntary isometric contraction: investigation of reliability and learning effect

scientific article published in April 2003

Measurement of Social Cognition in Amyotrophic Lateral Sclerosis: A Population Based Study

scientific article

Measuring life quality, physical function and psychological well-being in neurological illness

scientific article

Measuring network disruption in neurodegenerative diseases: New approaches using signal analysis

scientific article published on 13 February 2019

Measuring reliable change in cognition using the Edinburgh Cognitive and Behavioural ALS Screen (ECAS).

scientific article

Methodology and Design of a National Epidemiological Study on Adult Neuromuscular Disease

scientific article published on 05 November 2014

Methylprednisolone selectively affects dystrophin expression in human muscle cultures

article

Microdysgenesis in resected temporal neocortex: Incidence and clinical significance in focal epilepsy

scientific article published on 01 July 1988

Mismatch Negativity as an Indicator of Cognitive Sub-Domain Dysfunction in Amyotrophic Lateral Sclerosis

scientific article published on 15 August 2017

Models of care for motor neuron disease: setting standards

scientific article

Multicentre, cross-cultural, population-based, case-control study of physical activity as risk factor for amyotrophic lateral sclerosis

scientific article published on 23 April 2018

Multicentre, population-based, case-control study of particulates, combustion products and amyotrophic lateral sclerosis risk

scientific article published on 08 March 2019

Multidisciplinary Care in ALS: Expanding the Team ⬇️

scientific article published on February 1, 2012

Multiparametric MRI study of ALS stratified for the C9orf72 genotype

scientific article published on 14 June 2013

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis

scientific article

NEK1 variants confer susceptibility to amyotrophic lateral sclerosis

scientific article

Needs of informal caregivers across the caregiving course in amyotrophic lateral sclerosis: a qualitative analysis.

scientific article

Neuroimaging patterns along the ALS-FTD spectrum: a multiparametric imaging study

scientific article published on 31 May 2017

Neuropathic findings in oculopharyngeal muscular dystrophy. A report of seven cases and a review of the literature

scientific article published on May 1993

Neurophysiological markers of network dysfunction in neurodegenerative diseases

scientific article published on 02 February 2019

New clues to the evolutionary history of the main European paternal lineage M269: dissection of the Y-SNP S116 in Atlantic Europe and Iberia.

scientific article published on 17 June 2015

No association between soil constituents and amyotrophic lateral sclerosis relative risk in Ireland

scientific article published on 4 February 2016

No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis

scientific article

Ocular fixation instabilities in motor neurone disease. A marker of frontal lobe dysfunction?

scientific article published on 18 March 2009

On the development of markers for pathological TDP-43 in amyotrophic lateral sclerosis with and without dementia

scientific article published on 3 September 2011

Oral levosimendan in amyotrophic lateral sclerosis: a phase II multicentre, randomised, double-blind, placebo-controlled trial

scientific article published on 17 July 2019

Oropharyngeal dysphagia in amyotrophic lateral sclerosis: neurological and dysphagia specific rating scales

Palliative care in amyotrophic lateral sclerosis: a review of current international guidelines and initiatives

scientific article published on 05 February 2011

Palliative care in amyotrophic lateral sclerosis: a review of current international guidelines and initiatives

scientific article published on December 2011

Paramyotonia congenita and hyperkalemic periodic paralysis associated with a Met 1592 Val substitution in the skeletal muscle sodium channel alpha subunit--a large kindred with a novel phenotype

scientific article (publication date: March 1997)

Paraoxonase promoter and intronic variants modify risk of sporadic amyotrophic lateral sclerosis

scientific article

Pathological Crying and Laughing in Motor Neuron Disease: Pathobiology, Screening, Intervention

Patient and hospital delays in acute ischaemic stroke in a Dublin teaching hospital

scientific article published on 01 June 2003

Patient journey to a specialist amyotrophic lateral sclerosis multidisciplinary clinic: an exploratory study

scientific article published on 23 December 2015

Patients’ perceptions of services and preferences for care in amyotrophic lateral sclerosis: A review ⬇️

scientific article published on August 31, 2011

Patterned functional network disruption in amyotrophic lateral sclerosis

scientific article published on 26 July 2019

Patterns of cerebral and cerebellar white matter degeneration in ALS.

scientific article published on 21 July 2014

Perceptions of quality of life in people with ALS: effects of coping and health care

scientific article published in June 2007

Physical activity and amyotrophic lateral sclerosis: a European population-based case-control study

scientific article published on 21 May 2014

Physical decline and quality of life in amyotrophic lateral sclerosis

scientific article

Pitfalls in the diagnosis of motor neurone disease

scientific article

Polymyositis masquerading as motor neuron disease

scientific article published in July 2003

Post-polio Syndrome: More Than Just a Lower Motor Neuron Disease

scientific article published on 16 July 2019

Predicting prognosis in amyotrophic lateral sclerosis: a simple algorithm

scientific article published on 11 April 2015

Presymptomatic and longitudinal neuroimaging in neurodegeneration--from snapshots to motion picture: a systematic review

scientific article

Primary lateral sclerosis: a distinct entity or part of the ALS spectrum?

scientific article published on 18 January 2019

Proceedings of the Irish Neurological Association 24th Annual Scientific Meeting, Beaumont Hospital, May 1988

article by J. A. O’Dwyer et al published June 1989 in Irish Journal of Medical Science

Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model

scientific article published on 26 March 2018

Prognostic factors in ALS: A critical review

scientific article

Progranulin mutations and amyotrophic lateral sclerosis or amyotrophic lateral sclerosis-frontotemporal dementia phenotypes

scientific article

Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis

Proposed criteria for familial amyotrophic lateral sclerosis

Quantitative assessment of motor fatigue: Normative values and comparison with prior‐polio patients

article

Rapid clinical and CSF response to intravenous gamma globulin in acute disseminated encephalomyelitis

scientific article published on 01 November 2001

Rapid-onset dystonia-parkinsonism: A clinical and genetic analysis of a new kindred

article

Rate of familial amyotrophic lateral sclerosis: a systematic review and meta-analysis

scientific article

Reconsidering the causality of TIA1 mutations in ALS.

scientific article published on 13 December 2017

Recovery of the upper limb post ischaemic stroke and the predictive value of the Orpington Prognostic Score

scientific article published on 01 September 2004

Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis

scientific journal article

Reduced frequency of ALS in an ethnically mixed population: a population-based mortality study

scientific article

Referral bias in ALS epidemiological studies.

scientific article published on 16 April 2018

Respiratory measures in amyotrophic lateral sclerosis

scientific article published on 23 March 2018

Retrospective investigations of practice effects on repeated neuropsychological measures of executive functioning

Royal academy of medicine in Ireland

Royal academy of medicine in Ireland section of biomedical sciences

Royal academy of medicine in ireland

Screening for cognitive dysfunction in ALS: validation of the Edinburgh Cognitive and Behavioural ALS Screen (ECAS) using age and education adjusted normative data

scientific article

Screening for replication of genome-wide SNP associations in sporadic ALS

scientific journal article

Screening of hypoxia-inducible genes in sporadic ALS

article

Second-generation Irish genome-wide association study for amyotrophic lateral sclerosis

scientific article published on 6 September 2014

Sequencing and analysis of an Irish human genome

scientific article published on 7 September 2010

Service provision for patients with ALS/MND: a cost-effective multidisciplinary approach

scientific article published on October 1998

Sexual dimorphism in ALS: exploring gender-specific neuroimaging signatures.

scientific article published on 18 December 2013

Slow saccades in bulbar-onset motor neurone disease

scientific article published on 10 February 2010

Social cognition in neurodegenerative disorders: a systematic review

scientific article published on 06 August 2012

Social deprivation and population density are not associated with small area risk of amyotrophic lateral sclerosis

scientific article

Spatial cluster analysis of population amyotrophic lateral sclerosis risk in Ireland

scientific article published on 13 March 2015

Spatial cluster analysis of population amyotrophic lateral sclerosis risk in Ireland

scientific article published in November 2015

Spinal cord markers in ALS: diagnostic and biomarker considerations

scientific article published on 13 February 2012

Standards of palliative care for patients with amyotrophic lateral sclerosis: results of a European survey

scientific article published on 01 September 2001

Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach

scientific article published in Scientific Reports

Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach

Structural variation analysis of 6,500 whole genome sequences in amyotrophic lateral sclerosis

scientific article published on 28 January 2022

Subcortical gray matter structures: a future biomarker for amyotrophic lateral sclerosis?

article by Peter Bede & Orla Hardiman published March 2014 in Future Neurology

Survival analysis of geospatial factors in the Irish ALS cohort

scientific article published on 4 May 2016

Survival analysis of irish amyotrophic lateral sclerosis patients diagnosed from 1995-2010.

scientific article

Survival prediction in Amyotrophic lateral sclerosis based on MRI measures and clinical characteristics

scientific article

Symptomatic treatment of respiratory and nutritional failure in amyotrophic lateral sclerosis

scientific article

Ten years of the ALS journal

The "Spray Can" Sign

scientific article published on 01 October 2002

The C9orf72 expansion is associated with accelerated respiratory function decline in a large Amyotrophic Lateral Sclerosis cohort

scientific article published on 26 September 2019

The El Escorial criteria: Strengths and weaknesses

The Oxfordshire Community Stroke Project classification: correlation with imaging, associated complications, and prediction of outcome in acute ischemic stroke

scientific article

The Project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public

The Study of Language in the Amyotrophic Lateral Sclerosis - Frontotemporal Spectrum Disorder: a Systematic Review of Findings and New Perspectives.

scientific article published on 28 April 2018

The beginning of precision medicine in ALS? Treatment to fit the genes

scientific article published on 4 October 2017

The changing picture of amyotrophic lateral sclerosis: lessons from European registers

scientific article

The clinical and radiological profile of primary lateral sclerosis: a population-based study

scientific article published on 19 July 2019

The complex genetics of amyotrophic lateral sclerosis

article

The effect of SMN gene dosage on ALS risk and disease severity

scientific article published on 02 January 2021

The effects of a home-based arm ergometry exercise programme on physical fitness, fatigue and activity in Polio survivors: a randomised controlled trial

The effects of a home-based arm ergometry exercise programme on physical fitness, fatigue and activity in polio survivors: protocol for a randomised controlled trial.

scientific article

The epidemiology and treatment of ALS: focus on the heterogeneity of the disease and critical appraisal of therapeutic trials

scientific article

The epidemiology of ALS and the role of population-based registries

scientific article published on 29 September 2006

The epidemiology of ALS: a conspiracy of genes, environment and time

scientific article

The epidemiology of motor neuron disease in Northern Ireland using capture-recapture methodology

scientific article published on August 2010

The expansions of ALS

scientific article published on 25 July 2012

The heterogeneity of amyotrophic lateral sclerosis: a possible explanation of treatment failure

scientific article published on January 2007

The life expectancy of Stephen Hawking, according to the ENCALS model

scientific article published on 17 July 2018

The management of amyotrophic lateral sclerosis

scientific article published on 17 February 2009

The multistep hypothesis of ALS revisited: The role of genetic mutations

The orpington prognostic scale within the first 48 hours of admission as a predictor of outcome in ischemic stroke

article by Sean J Pittock et al published July 2003 in Journal of Stroke and Cerebrovascular Diseases

The oxidation of tryptamine by the two forms of monoamine oxidase in human tissues

scientific article

The path to specialist multidisciplinary care in amyotrophic lateral sclerosis: A population- based study of consultations, interventions and costs

scientific article

The segmental diffusivity profile of amyotrophic lateral sclerosis associated white matter degeneration

scientific article published on 21 May 2016

The selective anatomical vulnerability of ALS: ‘disease-defining’ and ‘disease-defying’ brain regions

The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study

scientific article published on 11 August 2011

Timeliness of diagnosis in motor neurone disease: a population-based study

scientific article published on January 2008

Tracking a Fast-Moving Disease: Longitudinal Markers, Monitoring, and Clinical Trial Endpoints in ALS

Trauma and amyotrophic lateral sclerosis: a european population-based case-control study from the EURALS consortium

scientific article

Treatment of refractory chronic daily headache with the atypical antipsychotic ziprasidone--a case series

scientific article

Truth or Consequences

scientific article published on 01 August 1998

Two heads are better than one: benefits of joint models for ALS trials

scientific article published on 11 April 2019

UBQLN2 mutations are not a frequent cause of amyotrophic lateral sclerosis in Ireland

scientific article published on 21 August 2013

Understanding psycho-social processes underpinning engagement with services in motor neurone disease: a qualitative study

scientific article

Understanding the use of NIV in ALS: results of an international ALS specialist survey

scientific article published on 16 April 2018

Use of Sniff nasal-inspiratory force to predict survival in amyotrophic lateral sclerosis.

scientific article

Using reference databases of genetic variation to evaluate the potential pathogenicity of candidate disease variants

scientific article published on 26 March 2013

VITALITY-ALS, a phase III trial of tirasemtiv, a selective fast skeletal muscle troponin activator, as a potential treatment for patients with amyotrophic lateral sclerosis: study design and baseline characteristics

scientific article published on 6 February 2018

Vacuolar leucoencephalopathy and pulvinar sign in association with coeliac disease

scientific article

Vacuolar leucoencephalopathy and pulvinar sign in association with coeliac disease

Validating population-based registers for ALS: how accurate is death certification?

scientific article published on 12 February 2010

Virtual brain biopsies in amyotrophic lateral sclerosis: Diagnostic classification based on in vivo pathological patterns

scientific article

Visual encoding, consolidation, and retrieval in amyotrophic lateral sclerosis: executive function as a mediator, and predictor of performance

scientific article published on 13 January 2017

Waterskier’s Hirayama syndrome

scientific article published on 19 April 2011

What does the ALSFRS-R really measure? A longitudinal and survival analysis of functional dimension subscores in amyotrophic lateral sclerosis

scientific article published on 25 November 2016

Willful Modulation of Brain Activity in Disorders of Consciousness

scientific article published on 01 May 2010

“Sand-watch” spinal cord: a case of inferior cervical spinal cord atrophy

scientific article published on 27 November 2013

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