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List of works by Guillaume Paré

A Digital Health Intervention to Lower Cardiovascular Risk: A Randomized Clinical Trial

scientific article published on 18 May 2016

A Prospective Study to Investigate Predictors of Relapse among Patients with Opioid Use Disorder Treated with Methadone

scientific article published on 10 April 2016

A Risk Assessment Tool Incorporating New Biomarkers for Cardiovascular Events in Acute Coronary Syndromes: The Organization to Assess Strategies in Ischemic Syndromes (OASIS) Risk Score

scientific article published on 2 February 2016

A fast algorithm to optimize SNP prioritization for gene-gene and gene-environment interactions.

scientific article published on 15 September 2011

A gene variant in CERS2 is associated with rate of increase in albuminuria in patients with diabetes from ONTARGET and TRANSCEND.

scientific article

A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium

scientific article published on 05 May 2013

A large-scale candidate gene association study of age at menarche and age at natural menopause

scientific article

A machine-learning heuristic to improve gene score prediction of polygenic traits.

scientific article published on 4 October 2017

A method to estimate the contribution of regional genetic associations to complex traits from summary association statistics

scientific article

A new method for measurement of total plasma PCSK9: clinical applications

scientific article published on January 2010

A robust method to estimate regional polygenic correlation under misspecified linkage disequilibrium structure

scientific article published on 29 August 2018

ACE and Type 2 Diabetes Risk: A Mendelian Randomization Study

scientific article published on 04 February 2020

Alcohol and Cardiovascular Disease: How Much is Too Much?

scientific article published on March 2017

Analytical strategies to include the X-chromosome in variance heterogeneity analyses: Evidence for trait-specific polygenic variance structure

scientific article published on 22 July 2019

Association between a literature-based genetic risk score and cardiovascular events in women

scientific article

Association between cannabis use and methadone maintenance treatment outcomes: an investigation into sex differences.

scientific article published on 30 March 2017

Association between shortened leukocyte telomere length and cardiometabolic outcomes: systematic review and meta-analysis

scientific article

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

scientific article published on 21 March 2019

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

scientific article published on 13 July 2020

Association of cyclooxygenase-2 genetic variant with cardiovascular disease

scientific article published on 5 May 2014

Association of variation at the ABO locus with circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin: a meta-analysis

scientific article published on 18 October 2011

Associations of the FTO rs9939609 variant with discrete body fat depots and dietary intake in a multi-ethnic cohort.

scientific article

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Blood CSF1 and CXCL12 as Causal Mediators of Coronary Artery Disease

scientific article published on 09 July 2018

Blood HER2 and Uromodulin as Causal Mediators of CKD.

scientific article published on 6 March 2018

Body mass index is negatively associated with telomere length: a collaborative cross-sectional meta-analysis of 87 observational studies

scientific article published in September 2018

COL4A2 is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls

scientific article published on 27 September 2017

CYP2C19 Genetic Testing Should Not Be Done in All Patients Treated With Clopidogrel Who Are Undergoing Percutaneous Coronary Intervention

Candidate genetic variants in the fibrinogen, methylenetetrahydrofolate reductase, and intercellular adhesion molecule-1 genes and plasma levels of fibrinogen, homocysteine, and intercellular adhesion molecule-1 among various race/ethnic groups: dat

scientific article

Cannabis use and risk of schizophrenia: a Mendelian randomization study.

scientific article published on 24 January 2017

Characterization of Patients with Embolic Strokes of Undetermined Source in the NAVIGATE ESUS Randomized Trial.

scientific article published on 7 March 2018

Clinical Validation of Fragile X Syndrome Screening by DNA Methylation Array.

scientific article published on 29 August 2016

Clinical Validation of a Genome-Wide DNA Methylation Assay for Molecular Diagnosis of Imprinting Disorders.

scientific article published on 11 August 2017

Clinical evaluation of a hemochromatosis next-generation sequencing gene panel.

scientific article

Combined vaccination and immunostimulatory antibodies provides durable cure of murine melanoma and induces transcriptional changes associated with positive outcome in human melanoma patients

scientific article

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

scientific article

Contribution of BDNF and DRD2 genetic polymorphisms to continued opioid use in patients receiving methadone treatment for opioid use disorder: an observational study

scientific article

Contribution of large region joint associations to complex traits genetics

scientific article

Current Evidence for Genetic Testing in Clopidogrel-Treated Patients Undergoing Coronary Stenting ⬇️

scientific article published on October 1, 2011

DNA methylation analysis in constitutional disorders: Clinical implications of the epigenome.

scientific article

Dabigatran etexilate and reduction in serum apolipoprotein B

scientific article published on 09 November 2015

Determinants of Left Atrial Volume in Patients with Atrial Fibrillation.

scientific article

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Does genetic heterogeneity account for the divergent risk of type 2 diabetes in South Asian and white European populations?

scientific article

Economic Considerations of Early Rule-In/Rule-Out Algorithms for The Diagnosis of Myocardial Infarction in The Emergency Department Using Cardiac Troponin and Glycemic Biomarkers

scientific article

Effect of PON1 Q192R Genetic Polymorphism on Clopidogrel Efficacy and Cardiovascular Events in the Clopidogrel in the Unstable Angina to Prevent Recurrent Events Trial and the Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Va

scholarly article by Guillaume Paré et al published April 2012 in Circulation: Cardiovascular Genetics

Effect of genetic variants associated with plasma homocysteine levels on stroke risk

scientific article

Effects of CYP2C19 genotype on outcomes of clopidogrel treatment

scientific article published on 29 August 2010

Effects of lifelong testosterone exposure on health and disease: a Mendelian randomization study

scientific article published on 16 October 2020

Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism.

scientific article

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article published in July 2017

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Evaluation of clinical and inflammatory profile in opioid addiction patients with comorbid pain: results from a multicenter investigation

scientific article

Examining the clinical use of hemochromatosis genetic testing

scientific article

Factors independently associated with cardiac troponin I levels in young and healthy adults from the general population

scientific article published on 17 August 2016

Fine mapping of the insulin-induced gene 2 identifies a variant associated with LDL cholesterol and total apolipoprotein B levels

scientific article published on 21 September 2010

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis

scientific article

Frameshift mutation in the APOA5 gene causing hypertriglyceridemia in a Pakistani family: Management and considerations for cardiovascular risk.

scientific article published on 9 August 2016

Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia.

scientific article published on 8 June 2015

Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry

scientific article

Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium

scientific article published on 12 September 2017

Genetic Predictors of Cardiovascular Mortality During Intensive Glycemic Control in Type 2 Diabetes: Findings From the ACCORD Clinical Trial

scientific article

Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial

scientific article published on 27 September 2018

Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol

scientific article published on 21 February 2007

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and phenotypic determinants of blood pressure and other cardiovascular risk factors (GAPP).

scientific article published on 8 January 2013

Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study.

scientific article published on 6 March 2017

Genetic determinants of dabigatran plasma levels and their relation to bleeding

scientific article

Genetic dissection of diabetes: facing the giant

scientific article published on October 2013

Genetic evidence of assortative mating in humans

article

Genetic influence on methadone treatment outcomes in patients undergoing methadone maintenance treatment for opioid addiction: a pilot study

scientific article

Genetic information and the prediction of incident type 2 diabetes in a high-risk multiethnic population: the EpiDREAM genetic study

scientific article published on 19 April 2013

Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication

scientific article published on October 2008

Genetic markers of inflammation and their role in cardiovascular disease.

scientific article published on 19 September 2012

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies

scientific article published on 5 October 2012

Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema

scientific article published on September 2013

Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes

scientific article

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

scientific article published on 7 September 2022

Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci

scientific article

Genome-wide association studies identify loci associated with age at menarche and age at natural menopause

scientific article

Genome-wide association studies--data generation, storage, interpretation, and bioinformatics.

scientific article

Genome-wide association study identifies 48 common genetic variants associated with handedness

scientific article published on 28 September 2020

Genome-wide association study meta-analysis of dizygotic twinning illuminates genetic regulation of female fecundity

scientific article published in 2023

Genome-wide studies to identify risk factors for kidney disease with a focus on patients with diabetes

scientific article published on August 2015

Genomic DNA Methylation Signatures Enable Concurrent Diagnosis and Clinical Genetic Variant Classification in Neurodevelopmental Syndromes

scientific article published in January 2018

Genomics and epigenomics in pediatric oncology and clinical laboratory genetics

scientific article published on 20 May 2014

Getting closer to p-selectin.

scientific article published on 16 April 2009

Global Assessment of Mendelian Stroke Genetic Prevalence in 101 635 Individuals From 7 Ethnic Groups

scientific article published on 28 February 2020

Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study

scientific article published on 15 July 2016

Growth Differentiation Factor 15 as a Novel Biomarker for Metformin

scientific article published on 14 December 2016

HDL Cholesterol, LDL Cholesterol, and Triglycerides as Risk Factors for CKD: A Mendelian Randomization Study

scientific article

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Identification of Cadherin 2 (CDH2) Mutations in Arrhythmogenic Right Ventricular Cardiomyopathy.

scientific article

Identification of Novel Causal Blood Biomarkers Linking Metabolically Favorable Adiposity With Type 2 Diabetes Risk

scientific article published on 24 June 2019

Identification of a methylation profile for DNMT1-associated autosomal dominant cerebellar ataxia, deafness, and narcolepsy

scientific article published on 05 September 2016

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

scientific article published on 4 September 2017

Identifying Novel Biomarkers for Cardiovascular Events or Death in People With Dysglycemia

scientific article published on 30 October 2015

Impact of Chronic Pain on Treatment Prognosis for Patients with Opioid Use Disorder: A Systematic Review and Meta-analysis

scientific article published in 2015

Impact of a Genetic Risk Score on Myocardial Infarction Risk Across Different Ethnic Populations

scientific article

Influenza virus H1N1 activates platelets through FcγRIIA signaling and thrombin generation.

scientific article

Interpreting metabolomic profiles using unbiased pathway models

scientific article

K45R variant of squalene synthase increases total cholesterol levels in two study samples from a French Canadian population.

scientific article

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article

Lifestyle interaction with fat mass and obesity-associated (FTO) genotype and risk of obesity in apparently healthy U.S. women ⬇️

scientific article

Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study

scientific article

Mendelian Genes and Risk of Intracerebral Hemorrhage and Small-Vessel Ischemic Stroke in Sporadic Cases

scientific article published on 5 July 2017

Mendelian randomisation, triglycerides, and CHD

scientific article published on 01 May 2010

Mendelian randomization analysis supports the causal role of dysglycaemia and diabetes in the risk of coronary artery disease

scientific article published on 29 March 2015

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis of SNPs involved in variance heterogeneity using Levene's test for equal variances.

scientific article published on 7 August 2013

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

scientific article

Methadone induces testosterone suppression in patients with opioid addiction

scientific article

Molecular phenotype and bleeding risks of an inherited platelet disorder in a family with a RUNX1 frameshift mutation

scientific article

Multi-ethnic genome-wide association study for atrial fibrillation

article

Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors

scientific article

Multiple loci associated with indices of renal function and chronic kidney disease

scientific journal article

Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes

scientific article published in March 2014

New loci associated with kidney function and chronic kidney disease

scientific article

Novel Biomarkers for Change in Renal Function in People With Dysglycemia

scientific article published on 14 November 2019

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women

scientific article

Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study

scientific article

Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study

scientific article published on 12 February 2009

On the use of variance per genotype as a tool to identify quantitative trait interaction effects: a report from the Women's Genome Health Study

scientific article

Opioid substitution and antagonist therapy trials exclude the common addiction patient: a systematic review and analysis of eligibility criteria

scientific article

Overlap Chronic Placental Inflammation Is Associated with a Unique Gene Expression Pattern.

scientific article published on 24 July 2015

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

scientific article published on 28 November 2016

PON1 Q192R genetic variant and response to clopidogrel and prasugrel: pharmacokinetics, pharmacodynamics, and a meta-analysis of clinical outcomes

article

PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD-Lipid

scientific article published on 23 January 2020

Peripheral Blood MCEMP1 Gene Expression as a Biomarker for Stroke Prognosis

scientific article published on 4 February 2016

Peripheral blood epi-signature of Claes-Jensen syndrome enables sensitive and specific identification of patients and healthy carriers with pathogenic mutations in KDM5C.

scientific article published on 14 February 2018

Pharmacogenetics in cardiovascular disease: the challenge of moving from promise to realization: concepts discussed at the Canadian Network and Centre for Trials Internationally Network Conference (CANNeCTIN), June 2009.

scientific article published on 17 September 2013

Pharmacogenetics of antiplatelets and anticoagulants: a report on clopidogrel, warfarin and dabigatran.

scientific article published on October 2013

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Pollen count and presentation of angiotensin-converting enzyme inhibitor-associated angioedema.

scientific article

Polygenic Contribution in Individuals With Early-Onset Coronary Artery Disease

scientific article published on 08 January 2018

Polygenic risk score predicts prevalence of cardiovascular disease in patients with familial hypercholesterolemia

scientific article published on 6 April 2017

Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study

scientific article

Population-based genomewide genetic analysis of common clinical chemistry analytes

scientific article

Promises and challenges of pharmacogenetics: an overview of study design, methodological and statistical issues

scientific article published on 05 April 2012

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 01 July 2019

Putting the Genome in Context: Gene-Environment Interactions in Type 2 Diabetes

scientific article

Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions

scientific article

Recommendations from the international stroke genetics consortium, part 2: biological sample collection and storage

scientific article

Relation between clopidogrel active metabolite levels and different platelet aggregation methods in patients receiving clopidogrel and aspirin

scientific article published on 01 November 2012

Relationships of Measured and Genetically Determined Height With the Cardiac Conduction System in Healthy Adults.

scientific article published on January 2017

Research capacity. Enabling the genomic revolution in Africa

scientific article published in June 2014

Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source

article published in 2018

Rule-In and Rule-Out of Myocardial Infarction Using Cardiac Troponin and Glycemic Biomarkers in Patients with Symptoms Suggestive of Acute Coronary Syndrome

scientific article

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study

scientific article published on 31 July 2013

Sex differences in outcomes of methadone maintenance treatment for opioid use disorder: a systematic review and meta-analysis

scientific article

Sex differences in substance use, health, and social functioning among opioid users receiving methadone treatment: a multicenter cohort study

scientific article

South Asian Heart Risk Assessment (SAHARA): Randomized Controlled Trial Design and Pilot Study

scientific article published on 20 August 2013

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

scientific article published on 21 March 2019

Telomere Length and Risk of Myocardial Infarction in a MultiEthnic Population: The INTERHEART Study

scientific article

Testosterone suppression in opioid users: a systematic review and meta-analysis

scientific article

The 9p21.3 locus and cardiovascular risk in familial hypercholesterolemia

scientific article published on 2 February 2017

The AIDS disease of CD4C/HIV transgenic mice shows impaired germinal centers and autoantibodies and develops in the absence of IFN-gamma and IL-6

scientific article published on 01 August 2001

The Genetic Link Between Diabetes and Atherosclerosis

scientific article published on 31 January 2018

The association between age of onset of opioid use and comorbidity among opioid dependent patients receiving methadone maintenance therapy

scientific article published on 28 March 2017

The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance.

scientific article published on 21 September 2017

The effectiveness of opioid substitution treatments for patients with opioid dependence: a systematic review and multiple treatment comparison protocol.

scientific article

The fat-mass and obesity-associated (FTO) gene, physical activity, and risk of incident cardiovascular events in white women

scientific article

The impact of chronic pain on opioid addiction treatment: a systematic review protocol

scientific article

The pharmacogenetics of carboxylesterases: CES1 and CES2 genetic variants and their clinical effect.

scientific article published on January 2014

The protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression

scientific article published on 20 November 2012

The relationship between CYP2C19 polymorphisms and ischaemic and bleeding outcomes in stable outpatients: the CHARISMA genetics study

article

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

scientific article

Towards the genetic basis of cerebral venous thrombosis-the BEAST Consortium: a study protocol.

scientific article

Use of genetic data to guide therapy in arterial disease

scientific article

Validation of the ORIGIN Cardiovascular Biomarker Panel and the Value of Adding Troponin I in Dysglycemic People

scientific article published on 24 March 2017

Variation at the DPP4 locus influences apolipoprotein B levels in South Asians and exhibits heterogeneity in Europeans related to BMI

article

Whole Blood Gene Expression Differentiates between Atrial Fibrillation and Sinus Rhythm after Cardioversion

scientific article

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