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List of works by Stuart Horswell

A genetic screen based on in vivo RNA imaging reveals centrosome-independent mechanisms for localizing gurken transcripts in Drosophila

scientific article

APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability

scientific article published on 9 January 2017

APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts

scientific article

Acute myeloid leukemia xenograft success prediction: Saving time

scientific article published on 15 December 2017

Author Correction: YAP1/TAZ drives ependymoma-like tumour formation in mice

scientific article published on 28 September 2020

BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer

scientific article

CDKN2B expression in adipose tissue of familial combined hyperlipidemia patients

scientific article published on 08 October 2013

Cancer heterogeneity and "the struggle for existence": diagnostic and analytical challenges

scientific article

Complement pathway gene activation and rising circulating immune complexes characterize early disease in HIV-associated tuberculosis

scientific article published on 16 January 2018

Deciphering clonality in aneuploid breast tumors using SNP array and sequencing data

scientific article

Detection of ubiquitous and heterogeneous mutations in cell-free DNA from patients with early-stage non-small-cell lung cancer

scientific article published on 28 January 2016

Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma

scientific article published on 28 October 2021

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

scientific article published on 11 April 2018

Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer

scientific article published on 01 September 2019

Development of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolution

scientific article

ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription

scientific article published on 26 February 2017

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

scientific article

Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution

scientific article published on 05 March 2020

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

scientific article (publication date: 8 March 2012)

Mutation of cancer driver MLL2 results in transcription stress and genome instability.

scientific article published on February 2016

New technologies for delineating and characterizing the lipid exome: prospects for understanding familial combined hyperlipidemia

scientific article

Overlapping BXSB congenic intervals, in combination with microarray gene expression, reveal novel lupus candidate genes

article

Pervasive chromosomal instability and karyotype order in tumour evolution

scientific article published on 02 September 2020

Prognostic impact of p62 expression in cutaneous malignant melanoma

scientific article

Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12

scientific article published on 06 April 2021

Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution

scientific article

Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts

scientific article published on 14 April 2014

SRF Co-factors Control the Balance between Cell Proliferation and Contractility

scientific article published on 5 November 2016

Severe hypercholesterolemia in four British families with the D374Y mutation in the PCSK9 gene: long-term follow-up and treatment response

scientific article

Small RNA profiling of Xenopus embryos reveals novel miRNAs and a new class of small RNAs derived from intronic transposable elements

scientific article published on 24 September 2013

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

scientific article

The Wilms Tumor-1 (WT1) rs2234593 variant is a prognostic factor in normal karyotype acute myeloid leukemia

The origin, global distribution, and functional impact of the human 8p23 inversion polymorphism

scientific article

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal

scientific article published on 4 April 2018

Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal

scientific article published on 9 April 2018

Tracking genomic cancer evolution for precision medicine: the lung TRACERx study

scientific article

Tracking the Evolution of Non-Small-Cell Lung Cancer

scientific article published on 26 April 2017

Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy

scientific article published on 23 May 2015