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List of works by Charles Swanton

89Zr-trastuzumab and 89Zr-bevacizumab PET to evaluate the effect of the HSP90 inhibitor NVP-AUY922 in metastatic breast cancer patients.

scientific article

9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy

scientific article published on 23 September 2021

A 3-gene proliferation score (TOP-FOX-67) can re-classify histological grade-2, ER-positive breast cancers into low- and high-risk prognostic categories

scientific article

A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS-Driven Lung Cancer

scientific article published on 19 February 2021

A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables

scientific article published on July 2011

A clonal expression biomarker associates with lung cancer mortality

scientific article published on 07 October 2019

A comparative analysis of the mutagenicity of platinum-containing chemotherapeutic agents reveals direct and indirect mutagenic mechanisms

scientific article published on 01 April 2021

A comprehensive survey of the mutagenic impact of common cancer cytotoxics

scientific article published on 9 May 2016

A phase 1 study evaluating the combination of an allosteric AKT inhibitor (MK-2206) and trastuzumab in patients with HER2-positive solid tumors

scientific article

A retrospective analysis of clinical outcome of patients with chemo-refractory metastatic breast cancer treated in a single institution phase I unit

scientific article

A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers

scientific article published on 23 February 2012

AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity

scientific article published on 14 April 2021

APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability

scientific article published on 9 January 2017

APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity

scientific article published on 19 June 2015

APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution

scientific article published on 8 January 2018

Abstract 983: Intratumor heterogeneity in non-small cell lung cancer inferred by multi-region exome sequencing

Academically led clinical trials: challenges and opportunities

scientific article published on 3 August 2015

Acquired resistance to crizotinib from a mutation in CD74-ROS1.

scientific article published in September 2013

Adapting clinical paradigms to the challenges of cancer clonal evolution

scientific article published on June 2013

Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: The CAPTURE study

scientific article published on 27 October 2021

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

scientific article published on 21 October 2017

Anthracycline cardiotoxicity

scientific article published on November 2006

Anti-cancer drug resistance: understanding the mechanisms through the use of integrative genomics and functional RNA interference.

scientific article published on 21 April 2010

Artificial intelligence in cancer imaging: Clinical challenges and applications

scholarly article by Wenya Linda Bi et al published 1 March 2019 in CA

Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast cancer: a retrospective analysis of five clinical trials

scientific article

Author Correction: Resolving genetic heterogeneity in cancer

scientific article published on 01 January 2020

BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer

scientific article

Biological and Therapeutic Impact of Intratumor Heterogeneity in Cancer Evolution

article published in 2015

Biological and therapeutic impact of intratumor heterogeneity in cancer evolution

scientific article

Breast cancer genome heterogeneity: a challenge to personalised medicine?

scientific article

CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid-specific cancer cell death through autophagy induction

scientific article published on 19 October 2011

Can oncology recapitulate paleontology? Lessons from species extinctions

scientific article

Cancer Evolution Constrained by the Immune Microenvironment

scientific article published in August 2017

Cancer chromosomal instability: therapeutic and diagnostic challenges

scientific article

Cancer evolution constrained by mutation order

scientific article

Cancer evolution: the final frontier of precision medicine?

scientific article published on March 2014

Cancer heterogeneity and "the struggle for existence": diagnostic and analytical challenges

scientific article

Cancer heterogeneity: implications for targeted therapeutics

scientific article

Cancer therapeutics through an evolutionary lens

Cancer: evolution within a lifetime

scientific article published on October 2014

Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability

scientific article

Cell-cycle targeted therapies

scientific article published on January 2004

Cellular Prion Protein PrPC and Ecto-5'-Nucleotidase Are Markers of the Cellular Stress Response to Aneuploidy

scientific article

Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease

scientific article published on September 2016

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

scientific article published on 15 April 2021

Chromosomal instability confers intrinsic multidrug resistance.

scientific article

Chromosomal instability determines taxane response

scholarly article

Chromosomal instability drives metastasis through a cytosolic DNA response

scientific article published on 17 January 2018

Chromosomal instability selects gene copy-number variants encoding core regulators of proliferation in ER+ breast cancer.

scientific article

Chromosomal instability, aneuploidy, and cancer

scientific article published on 19 June 2014

Chromosomal instability, colorectal cancer and taxane resistance

scientific article

Chromosomal instability: a composite phenotype that influences sensitivity to chemotherapy

scientific article published on 31 October 2009

Circulating tumor DNA analyses reveal novel resistance mechanisms to CDK inhibition in metastatic breast cancer

scientific article published on 17 January 2018

Classifying the evolutionary and ecological features of neoplasms

scientific article published on 15 September 2017

Clinical Implications of Genomic Discoveries in Lung Cancer

scientific article published on May 2016

Clinical management of breast cancer heterogeneity

scientific article published on 21 April 2015

Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine

scientific article

Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future

scientific article published on February 2017

Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment

scientific article published on 19 March 2021

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

scientific article published on 03 March 2016

Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

scientific article

Collateral damage: the impact on cancer outcomes of the COVID-19 pandemic

scientific article published on 25 April 2020

Combined inhibition of BRAF and MEK in melanoma patients

scientific article published on 15 July 2014

Computational optimisation of targeted DNA sequencing for cancer detection.

scientific article published on 3 December 2013

Concordance of exon array and real-time PCR assessment of gene expression following cancer cell cytotoxic drug exposure

scientific article published on 17 December 2008

Consensus on precision medicine for metastatic cancers: a report from the MAP conference.

scientific article published on 3 May 2016

Consequences of COVID-19 for cancer care - a CRUK perspective

scientific article published on 23 October 2020

Constraints in cancer evolution

scientific article published on February 2017

Correction: The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE".

scientific article published on 21 April 2017

Cyclin D mediates tolerance of genome-doubling in cancers with functional p53.

scientific article

DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer

scientific article

Deciphering clonality in aneuploid breast tumors using SNP array and sequencing data

scientific article

Deciphering intratumor heterogeneity and temporal acquisition of driver events to refine precision medicine

scientific article

Deciphering root causes of intrinsic BRAF inhibitor resistance in melanoma: ushering in a new genomics case reports feature for Annals of Oncology

scientific article

DeconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution

scientific article published on 22 February 2016

Delivering preventive, predictive and personalised cancer medicine for renal cell carcinoma: the challenge of tumour heterogeneity

scientific article published on 22 December 2011

Detection of ubiquitous and heterogeneous mutations in cell-free DNA from patients with early-stage non-small-cell lung cancer

scientific article published on 28 January 2016

Determinants and clinical implications of chromosomal instability in cancer

scientific article published on 3 January 2018

Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma

scientific article published on 28 October 2021

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

scientific article published on 11 April 2018

Development of Tumor Mutation Burden as an Immunotherapy Biomarker: Utility for the Oncology Clinic

scientific article published in January 2019

Development of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolution

scientific article

Differential binding affinity of mutated peptides for MHC class I is a predictor of survival in advanced lung cancer and melanoma

scientific article

Environmental emissions, public health and lung cancer risk

article

Epigenetic Noise Fuels Cancer Evolution

Epigenetic regulation in RCC: opportunities for therapeutic intervention?

scientific article published on 17 January 2012

Epothilones and new analogues of the microtubule modulators in taxane-resistant disease

Erratum: Corrigendum: Replication stress links structural and numerical cancer chromosomal instability

scientific article published in Nature

Escape from nonsense-mediated decay associates with anti-tumor immunogenicity

scientific article published on 30 July 2020

Evaluating the significance of density, localization, and PD-1/PD-L1 immunopositivity of mononuclear cells in the clinical course of lung adenocarcinoma patients with brain metastasis.

scientific article

Evolution and cancer medicine — transformative insights

article published in 2017

Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers.

scientific article published on 6 November 2017

Evolutionary Precision Medicine: A Role for Repeat Epidermal Growth Factor Receptor Analysis in ALK-Rearranged Lung Adenocarcinoma?

scientific article

Evolutionary dynamics in pre-invasive neoplasia.

scientific article

Evolving adoptive cellular therapies in urological malignancies

scientific article published on June 2017

Expansion of airway basal epithelial cells from primary human non-small cell lung cancer tumors

scientific article published on 22 March 2018

Expression of regulators of mitotic fidelity are associated with intercellular heterogeneity and chromosomal instability in primary breast cancer

scientific article published on 7 October 2014

Extreme chromosomal instability forecasts improved outcome in ER-negative breast cancer: a prospective validation cohort study from the TACT trial

scientific article published on 23 May 2015

FKBPL regulates estrogen receptor signaling and determines response to endocrine therapy

scientific article

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

scientific article

Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors

scientific article

From genomic landscapes to personalized cancer management—is there a roadmap? ⬇️

scientific article published on October 1, 2010

Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer

scientific article published on 31 October 2008

Gastrointestinal cancer: Tracking tumour evolution through liquid biopsy

scientific article published on 8 September 2015

Genetic prognostic and predictive markers in colorectal cancer

scientific article published on 18 June 2009

Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target

scientific article

Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer

scientific article published on 12 April 2018

Genomic analyses to select patients for adjuvant chemotherapy: trials and tribulations.

scientific article

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

scientific article

Genomic instability in mutant p53 cancer cells upon entotic engulfment

scientific article published in Nature Communications

Genomic landscape of platinum resistant and sensitive testicular cancers

scientific article published on 04 May 2020

Geospatial immune variability illuminates differential evolution of lung adenocarcinoma

scientific article published on 27 May 2020

Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome

scientific article published on 2 March 2015

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis

scientific article published on 04 September 2013

Her2-targeted therapies in non-small cell lung cancer

scientific article published on July 2006

Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins.

scientific article

How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine ⬇️

scientific article published on September 28, 2010

How should clinicians address intratumour heterogeneity in clear cell renal cell carcinoma?

scientific article published on September 2015

Implications of cancer evolution for drug development

scientific article published on 28 April 2017

Implications of intratumour heterogeneity for treatment stratification

scientific article published on January 2014

Incidence, pattern and timing of brain metastases among patients with advanced breast cancer treated with trastuzumab

scientific article published in January 2006

Inferring mutational timing and reconstructing tumour evolutionary histories

scientific article

Initiation of high frequency multi-drug resistance following kinase targeting by siRNAs

scientific article published on 4 June 2007

Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis

scientific article published on 07 July 2017

Integrating molecular mechanisms and clinical evidence in the management of trastuzumab resistant or refractory HER-2⁺ metastatic breast cancer.

scientific article published on 21 October 2011

Inter and intratumour heterogeneity: a barrier to individualized medical therapy in renal cell carcinoma?

scientific article

International cancer seminars: a focus on kidney cancer ⬇️

scientific article published on 29 April 2016

Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution

scientific article published on 05 March 2020

Intra-tumor heterogeneity: lessons from microbial evolution and clinical implications

scientific article

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

scientific article (publication date: 8 March 2012)

Intratumor heterogeneity: evolution through space and time ⬇️

scientific article published on September 20, 2012

Intratumor heterogeneity: seeing the wood for the trees

scientific article

Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma

scientific article published on 12 April 2017

Intratumour heterogeneity in urologic cancers: from molecular evidence to clinical implications

scientific article published on 02 May 2014

Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters

scientific article published in October 2017

KRAS 3′-UTR variants and stratification of breast-cancer risk

scientific article published on 22 March 2011

Kidney cancer: The next decade

scientific article published on 14 September 2018

LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development.

scientific article published on March 2013

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes.

scientific article published on 29 August 2016

Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions.

scientific article published on 25 July 2016

MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically

scientific article published on 10 September 2020

Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

scientific article published on 27 January 2021

Metastasis and immune evasion from extracellular cGAMP hydrolysis

scientific article published on 28 December 2020

Metastasis as an evolutionary process

scientific article published on April 2016

Minimising immunohistochemical false negative ER classification using a complementary 23 gene expression signature of ER status

scientific article

Modelling the evolution of genetic instability during tumour progression

scientific article published on 26 November 2012

Modulation of p27(Kip1) levels by the cyclin encoded by Kaposi's sarcoma-associated herpesvirus

scientific article

Molecular classification of solid tumours: towards pathway-driven therapeutics

scientific article published on 14 April 2009

Molecular profiling and the reclassification of cancer: divide and conquer

scientific article published on January 2013

Multidisciplinary urological engagement in translational renal cancer research

scientific article published on 28 July 2014

Neoantigen quality, not quantity

scientific article published on 01 August 2019

New approaches for improving outcomes in breast cancer in Europe

scientific article published on 31 March 2015

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.

scientific article

Optimizing treatment of metastatic renal cell carcinoma by changing mechanism of action

scientific article published on April 2011

Origins of lymphatic and distant metastases in human colorectal cancer.

scientific article

Overcoming inhibitions: subversion of CKI function by viral cyclins.

scientific article

Paradoxical relationship between chromosomal instability and survival outcome in cancer

scientific article

Parallel evolution of tumour subclones mimics diversity between tumours

scientific article published in August 2013

Patupilone in patients with pretreated metastatic/locally recurrent colorectal cancer: results of the Phase II CINATRA trial

scientific article published on 26 June 2013

Percutaneous endoscopic gastrostomy at the time of tumour resection in advanced oral cancer.

scientific article published in September 2000

Personalization of prostate cancer prevention and therapy: are clinically qualified biomarkers in the horizon?

scientific article published on 12 January 2012

Pervasive chromosomal instability and karyotype order in tumour evolution

scientific article published on 02 September 2020

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

scientific article

Plasma-Derived Tumor DNA Analysis at Whole-Genome Resolution ⬇️

scientific article published on October 31, 2012

Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets

scientific article

Predictive performance of microarray gene signatures: impact of tumor heterogeneity and multiple mechanisms of drug resistance

scientific article

Preexisting and de novo humoral immunity to SARS-CoV-2 in humans

scientific article published on 06 November 2020

Principles of Targeted and Biological Therapies

Prioritizing targets for precision cancer medicine

scientific article

Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery

scientific article published on 29 March 2010

Prognostic and predictive markers in metastatic renal cell carcinoma

scientific article published on 7 January 2013

Promoting predictive, preventive and personalised medicine: European event of global importance

scientific article

Pruning Cancer's Evolutionary Tree with Lesion-Directed Therapy

scientific article published on February 2016

Publisher Correction: A clonal expression biomarker associates with lung cancer mortality

scientific article published on 03 June 2020

Publisher Correction: Genomic instability in mutant p53 cancer cells upon entotic engulfment

scientific article published in Nature Communications

Publisher Correction: Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

scientific article published on 03 June 2020

Publisher Correction: Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

scientific article published on 03 June 2020

Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

scientific article published on 07 October 2019

Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection.

scientific article

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress.

scientific article published on 9 November 2015

RNA interference, DNA methylation, and gene silencing: a bright future for cancer therapy?

scientific article

RNAi-mediated functional analysis of pathways influencing cancer cell drug resistance.

scientific article published on 21 May 2009

Re-Evaluating Clonal Dominance in Cancer Evolution

scientific article published on 27 April 2016

Recent developments in treatment stratification for metastatic breast cancer

scientific article

Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution

scientific article

Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

scientific article

Relapse models for clear cell renal carcinoma

scientific article published on 01 August 2015

Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer

scientific article

Renal cell carcinoma

scientific article

Replication stress links structural and numerical cancer chromosomal instability

scientific article published on February 2013

Reply to the letter to the editor ‘Abandoning diesel because of health perspectives: are there reasonable alternatives?’ by Vreugdenhil and Mannaerts

article

Resolving genetic heterogeneity in cancer

scientific article published on 01 July 2019

Response to Bakhoum et al.

scientific article published in February 2014

SAFIR01: steps towards precision treatment in breast cancer

scientific article published on 07 February 2014

SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

scientific article

Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis

scientific article published on 14 April 2020

Simplified, low-cost gene expression profiling for the prediction of outcome in breast cancer based on routine histologic specimens

scientific article published in April 2013

SnapShot: Renal Cell Carcinoma

scientific article published in December 2015

Spatial and temporal cancer evolution: causes and consequences of tumour diversity

scientific article

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

scientific article

Spatial heterogeneity in medulloblastoma

scientific article published on 10 April 2017

Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

scientific article published on 07 October 2019

Strategies in subversion: de-regulation of the mammalian cell cycle by viral gene products

scientific article

Systematic evaluation of the prognostic impact and intratumour heterogeneity of clear cell renal cell carcinoma biomarkers

scientific article published on 19 July 2014

Systemic therapy for advanced renal cell carcinoma

scientific article published on July 2009

Targeted Therapy for Advanced Solid Tumors on the Basis of Molecular Profiles: Results From MyPathway, an Open-Label, Phase IIa Multiple Basket Study

scientific article published on 10 January 2018

Targeting chromosomal instability and tumour heterogeneity in HER2-positive breast cancer

scientific article

Targeting polo-like kinase: learning too little too late?

scientific article published on 27 October 2008

Taxane benefit in breast cancer--a role for grade and chromosomal stability

scientific article published on 07 May 2013

Tetraploidy and CIN: a dangerous combination

scientific article

The CIN4 chromosomal instability qPCR classifier defines tumor aneuploidy and stratifies outcome in grade 2 breast cancer.

scientific article

The Emergence of Precision Urologic Oncology: A Collaborative Review on Biomarker-driven Therapeutics

scientific article published on 23 August 2016

The European Society for Medical Oncology (ESMO) Precision Medicine Glossary

scientific article published on 13 November 2017

The GENIE Is Out of the Bottle: Landmark Cancer Genomics Dataset Released

scientific article

The National Lung Matrix Trial of personalized therapy in lung cancer

scientific article published on 15 July 2020

The National Lung Matrix Trial: translating the biology of stratification in advanced non-small-cell lung cancer

scientific article

The Role of Aneuploidy in Cancer Evolution

scientific article published on 3 January 2017

The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE".

scientific article

The Value of Patient and Public Involvement in Trial Design and Development

article

The causes and consequences of genetic heterogeneity in cancer evolution

scientific article (publication date: 19 September 2013)

The centriolar satellite protein Cep131 is important for genome stability

scientific article

The evolution of the unstable cancer genome

scientific article published on 31 December 2013

The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel

scientific article

The future of UK healthcare: problems and potential solutions to a system in crisis.

scientific article

The genome of the chicken DT40 bursal lymphoma cell line.

scientific article

The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome

scientific article

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal

scientific article published on 4 April 2018

Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution.

scientific article

Toward understanding and exploiting tumor heterogeneity

scientific article

Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal

scientific article published on 9 April 2018

Tracking genomic cancer evolution for precision medicine: the lung TRACERx study

scientific article

Tracking the Evolution of Non-Small-Cell Lung Cancer

scientific article published on 26 April 2017

Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy

scientific article published on 23 May 2015

Translational implications of tumor heterogeneity

scientific article

Treatment-Induced Mutagenesis and Selective Pressures Sculpt Cancer Evolution

scientific article published on 13 March 2017

Tumor Evolution as a Therapeutic Target

scientific article

Tumor Evolutionary Principles: How Intratumor Heterogeneity Influences Cancer Treatment and Outcome

scientific article published on January 2016

TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen

scientific article (publication date: October 2015)

Tumour heterogeneity and drug resistance: Personalising cancer medicine through functional genomics ⬇️

scientific article published on December 16, 2011

Tumour heterogeneity and immune-modulation

scientific article published on 07 May 2013

Tumour heterogeneity and the evolution of polyclonal drug resistance

scientific article

Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas

scientific article

Unlocking Pandora's box: personalising cancer cell death in non-small cell lung cancer

scientific article

Unraveling the complexity of endocrine resistance in breast cancer by functional genomics

scientific article

Urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment

scientific article published on 26 September 2018

Utility of prognostic genomic tests in breast cancer practice: The IMPAKT 2012 Working Group Consensus Statement

scientific article

Whole Genome Doubling mitigates Muller's Ratchet in Cancer Evolution: Supplementary figures

Whole genome RNA expression profiling of endoscopic biliary brushings provides data suitable for biomarker discovery in cholangiocarcinoma

scientific article

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