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List of works by Heather E Wheeler

A gene-based association method for mapping traits using reference transcriptome data

scientific article

Application of stem cell derived neuronal cells to evaluate neurotoxic chemotherapy.

scientific article published on 15 June 2017

Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia

scientific article

Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies.

scientific article

Chronic circadian misalignment results in reduced longevity and large-scale changes in gene expression in Drosophila

article

Clinical and Genome-Wide Analysis of Cisplatin-Induced Peripheral Neuropathy in Survivors of Adult-Onset Cancer

scientific article published on 13 June 2017

Clinical and Genome-Wide Analysis of Multiple Severe Cisplatin-Induced Neurotoxicities in Adult-Onset Cancer Survivors

scientific article published on 30 September 2020

Clinical and Genome-Wide Analysis of Serum Platinum Levels after Cisplatin-Based Chemotherapy

scientific article published on 11 July 2019

Clinical and Genome-wide Analysis of Cisplatin-induced Tinnitus Implicates Novel Ototoxic Mechanisms

scientific article published on 05 April 2019

Clinical translation of cell-based pharmacogenomic discovery

scientific article published on 22 August 2012

Common variants in Mendelian kidney disease genes and their association with renal function

scientific article published on 12 September 2013

Comprehensive Audiometric Analysis of Hearing Impairment and Tinnitus After Cisplatin-Based Chemotherapy in Survivors of Adult-Onset Cancer

scientific article

Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients

scientific article published on 28 March 2013

EPS8 inhibition increases cisplatin sensitivity in lung cancer cells

scientific article

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.

scientific article published on 8 May 2018

Fine-mapping and QTL tissue-sharing information improves the reliability of causal gene identification

scientific article published on 10 September 2020

Functional consequences of PRPF39 on distant genes and cisplatin sensitivity

scientific article published on 5 July 2012

Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.

scientific article published on 29 January 2018

Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach

scientific article published on 18 March 2017

Genetic and epigenetic variants contributing to clofarabine cytotoxicity

scientific article published on 29 May 2013

Genetic architecture of gene expression traits across diverse populations

scholarly article published 10 January 2018

Genetic architecture of gene expression traits across diverse populations

article

Genetic regulatory variation in populations informs transcriptome analysis in rare disease

scientific article published on 10 October 2019

Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations

scientific article published on 01 April 2021

Genetically regulated gene expression underlies lipid traits in Hispanic cohorts

scientific article published on 08 August 2019

Genetics and genomics of human ageing

scientific article

Genome-wide association and functional follow-up reveals new loci for kidney function

scientific article

Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans

scientific article

Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations

scientific article

Identification of genetic variants associated with capecitabine-induced hand-foot syndrome through integration of patient and cell line genomic analyses

scientific article

Identification of novel germline polymorphisms governing capecitabine sensitivity.

scientific article

Imputed gene associations identify replicable trans-acting genes enriched in transcription pathways and complex traits

scientific article published on 04 April 2019

Integrating predicted transcriptome from multiple tissues improves association detection

scientific article published on 22 January 2019

Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy

scientific article published on 30 November 2012

Integration of genetic and functional genomics data to uncover chemotherapeutic induced cytotoxicity

scientific article published on 25 May 2018

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

scientific article published on 8 September 2012

Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation

scientific article published on January 2012

Modeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cells

scientific article (publication date: 2015)

Multi-ethnic transcriptome-wide association study of prostate cancer

scientific article published on 28 September 2020

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

scientific article published in Nature Communications

Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy

scientific article

Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy

scientific article published on 3 May 2016

Pharmacokinetics and pharmacogenomics of daunorubicin in children: a report from the Children's Oncology Group

scientific article

Poly-omic prediction of complex traits: OmicKriging

scientific article

Population-Matched Transcriptome Prediction Increases TWAS Discovery and Replication Rate

scientific article published on 23 November 2020

Regulatory polymorphisms in β-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy.

scientific article published on 20 June 2012

Relating human genetic variation to variation in drug responses

scientific article

Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging

scientific article published in October 2009

Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues

scientific article

Transcriptome association studies of neuropsychiatric traits in African Americans implicate PRMT7 in schizophrenia

scientific article published on 26 September 2019

Variants in WFS1 and Other Mendelian Deafness Genes Are Associated with Cisplatin-Associated Ototoxicity

scientific article published on 30 December 2016

Whole-genome studies identify solute carrier transporters in cellular susceptibility to paclitaxel

scientific article

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