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List of works by Stephen M. Hewitt

4-HNE Immunohistochemistry and Image Analysis for Detection of Lipid Peroxidation in Human Liver Samples Using Vitamin E Treatment in NAFLD as a Proof of Concept

scientific article published on 01 September 2020

A Buffered Alcohol-Based Fixative for Histomorphologic and Molecular Applications

scientific article published on 24 May 2016

A Multiplex Tissue Immunoblotting Assay for Proteomic Profiling: A Pilot Study of the Normal to Tumor Transition of Esophageal Squamous Cell Carcinoma

scientific article published on 01 July 2006

A Novel Quantitative Multiplex Tissue Immunoblotting for Biomarkers Predicts a Prostate Cancer Aggressive Phenotype.

scientific article published on 24 September 2015

A Recurrent Chromosome Breakpoint in Breast Cancer at theNRG1/Neuregulin 1/HeregulinGene

article

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis

scientific article published on 11 May 2015

A cryptic BAP1 splice mutation in a family with uveal and cutaneous melanoma, and paraganglioma

scientific article published in October 2012

A melanin-bleaching methodology for molecular and histopathological analysis of formalin-fixed paraffin-embedded tissue

scientific article published on 22 August 2016

A multiprotein supercomplex controlling oncogenic signalling in lymphoma

scientific article published in Nature

A pressure cooking-based DNA extraction from archival formalin-fixed, paraffin-embedded tissue.

scientific article

A randomized controlled trial of octreotide pamoate long-acting release and carboplatin versus carboplatin alone in dogs with naturally occurring osteosarcoma: evaluation of insulin-like growth factor suppression and chemotherapy.

scientific article

A transatlantic perspective on the integration of immuno-oncology prognostic and predictive biomarkers in innovative clinical trial design

scientific article published on 4 January 2018

A well-based reverse-phase protein array applicable to extracts from formalin-fixed paraffin-embedded tissue.

scientific article

A well-based reverse-phase protein array of formalin-fixed paraffin-embedded tissue

scientific article published on January 2015

ALDH1A2 Is a Candidate Tumor Suppressor Gene in Ovarian Cancer

scientific article published on 14 October 2019

API5 confers cancer stem cell-like properties through the FGF2-NANOG axis.

scientific article published on 16 January 2017

APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors

scientific article published on 01 March 2019

APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R

article

AR-regulated TWEAK-FN14 pathway promotes prostate cancer bone metastasis

scientific article published on 26 June 2014

Aberrant nucleocytoplasmic localization of the retinoblastoma tumor suppressor protein in human cancer correlates with moderate/poor tumor differentiation

scientific article published on 10 December 2007

Acute Kidney Injury Biomarkers - Needs, Present Status, and Future Promise

scientific article published on March 2006

Ages at menarche- and menopause-related genetic variants in relation to terminal duct lobular unit involution in normal breast tissue

scientific article published on 24 June 2016

Agreement in Histological Assessment of Mitotic Activity Between Microscopy and Digital Whole Slide Images Informs Conversion for Clinical Diagnosis

scientific article published on 01 January 2019

Altered cytoplasmic-to-nuclear ratio of survivin is a prognostic indicator in breast cancer

scientific article

An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers

scientific article

Analysis of terminal duct lobular unit involution in luminal A and basal breast cancers

scientific article

Analysis of the expression of human tumor antigens in ovarian cancer tissues

scientific article

Antiangiogenic and antitumor effects of bevacizumab in patients with inflammatory and locally advanced breast cancer

scientific article published on 3 January 2006

Apoptosis inhibitor-5 overexpression is associated with tumor progression and poor prognosis in patients with cervical cancer

scientific article

Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials

scientific article published on 12 May 2020

Application of convolutional neural networks to breast biopsies to delineate tissue correlates of mammographic breast density

scientific article published on 19 November 2019

Application of selected reaction monitoring for multiplex quantification of clinically validated biomarkers in formalin-fixed, paraffin-embedded tumor tissue

scientific article published on 11 May 2013

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Ca

scientific article published on 2 August 2017

Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in I

scientific article published in September 2017

Assessment of a panel of tumor markers for the differential diagnosis of benign and malignant effusions by well-based reverse phase protein array.

scientific article published on 29 May 2015

Assessment of automated image analysis of breast cancer tissue microarrays for epidemiologic studies

scientific article

Assessment of vascular endothelial growth factor in formalin fixed, paraffin embedded colon cancer specimens by means of a well-based reverse phase protein array

scientific article

Associated expressions of FGFR-2 and FGFR-3: from mouse mammary gland physiology to human breast cancer

scientific article

Association between breast cancer genetic susceptibility variants and terminal duct lobular unit involution of the breast

scientific article published on 9 November 2016

Association of prion protein expression with pancreatic adenocarcinoma survival in the SEER residual tissue repository

scientific article published on January 2011

Associations between selected biomarkers and prognosis in a population-based pancreatic cancer tissue microarray

scientific article published on 10 March 2009

Author Correction: PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis

scientific article published on 01 December 2020

Automated Computational Detection, Quantitation, and Mapping of Mitosis in Whole-Slide Images for Clinically Actionable Surgical Pathology Decision Support

Automated area calculation of histopathologic features using SIVQ.

scientific article

Automated evaluation of HER-2/neu immunohistochemical expression in breast cancer using digital microscopy

Automated prostate tissue referencing for cancer detection and diagnosis

scientific article

Automated quantitative assessment of HER-2/neu immunohistochemical expression in breast cancer

scientific article published on 19 January 2009

Automatic detection of melanoma progression by histological analysis of secondary sites.

scientific article published on 29 March 2012

Bcl-2-like Protein 11 (BIM) Expression Is Associated with Favorable Prognosis for Patients with Cervical Cancer

scientific article

Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure

scientific article published on 7 June 2006

Biomarkers of apoptosis and survival in esophageal squamous cell carcinoma

scientific article

Birt-Hogg-Dubé syndrome, a genodermatosis associated with spontaneous pneumothorax and kidney neoplasia, maps to chromosome 17p11.2.

scientific article

Breast cancer susceptibility risk associations and heterogeneity by E-cadherin tumor tissue expression

scientific article

Brightfield proximity ligation assay reveals both canonical and mixed transforming growth factor-β/bone morphogenetic protein Smad signaling complexes in tissue sections.

scientific article

CD44 is prognostic for overall survival in the NCI randomized trial on breast conservation with 25 year follow-up

scientific article

CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive Rhabdomyosarcoma

scientific article

CDK7 is a reliable prognostic factor and novel therapeutic target in epithelial ovarian cancer

scientific article published on 24 November 2019

CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells

scientific article

CLSI releases updated Guideline for the Development of Immunohistochemical Assays

scientific article

Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression

scientific article

Cell microarray platform for anticancer drug development

article

Cell-cycle control in urothelial carcinoma: large-scale tissue array analysis of tumor tissue from Maine and Vermont

scientific article

Cell-cycle protein expression in a population-based study of ovarian and endometrial cancers

scientific article

Characterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody

scientific article published on 11 July 2013

Characterizations and validations of novel antibodies toward translational research

scientific article published on 26 March 2010

Chemoradiotherapy response prediction model by proteomic expressional profiling in patients with locally advanced cervical cancer

scientific article published on 24 February 2020

Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.

scientific article published in July 2004

Circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3 and terminal duct lobular unit involution of the breast: a cross-sectional study of women with benign breast disease

scientific article published on 18 February 2016

Circulating sex hormones and terminal duct lobular unit involution of the normal breast

scientific article

Clinical significance of OCT4 and SOX2 protein expression in cervical cancer

scientific article published on 26 December 2015

Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T-Cell Receptors in High-Risk MYCN-Not-Amplified Human Neuroblastoma

scientific article published on 21 May 2018

Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer

scientific article published on 01 April 2020

Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma.

scientific article published on 6 June 2017

Comparative evaluation of super high-resolution CT scan and virtual bronchoscopy for the detection of tracheobronchial malignancies

scientific article published in November 2003

Complete Remission in the Nephrotic Syndrome Study Network

scientific article

Computational analysis of the mesenchymal signature landscape in gliomas

scientific article

Computer aided diagnostic tools aim to empower rather than replace pathologists: Lessons learned from computational chess ⬇️

scientific article published on June 14, 2011

Consensus recommendations on estrogen receptor testing in breast cancer by immunohistochemistry

scientific article published on December 2008

Consistency and standardization of color in medical imaging: a consensus report ⬇️

scientific article

Construction and validation of tissue microarrays of ductal carcinoma in situ and terminal duct lobular units associated with invasive breast carcinoma

scientific article published in September 2006

Controls for immunohistochemistry: the Histochemical Society's standards of practice for validation of immunohistochemical assays

scientific article

Correction: Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF

scientific article published on 01 December 2018

Correlation between clinical outcome and growth factor pathway expression in osteogenic sarcoma

scientific article

Credentialing preclinical pediatric xenograft models using gene expression and tissue microarray analysis

scientific article published on January 2007

Cytokeratin immunoexpression in esophageal squamous cell carcinoma of high-risk population in Northeast India

scientific article

DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancer

scientific article published on 26 May 2009

DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells

scientific article

Deciphering von Hippel-Lindau (VHL/Vhl)-associated pancreatic manifestations by inactivating Vhl in specific pancreatic cell populations

scientific article

Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach

scientific article published on 16 January 2013

Design, construction, and use of tissue microarrays

scientific article published on January 2004

Desmoglein 3 as a prognostic factor in lung cancer.

scientific article published on 3 November 2006

Detection of somatic mutations by high-resolution DNA melting (HRM) analysis in multiple cancers

scientific article

Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer

scientific article published on 17 September 2019

Development and evaluation of deep learning-based segmentation of histologic structures in the kidney cortex with multiple histologic stains

scientific article published on 21 August 2020

Diagnostic markers that distinguish colon and ovarian adenocarcinomas: identification by genomic, proteomic, and tissue array profiling

article

Diesel exhaust and bladder cancer risk by pathologic stage and grade subtypes

scientific article published on 18 December 2019

Differences in risk factors for breast cancer molecular subtypes in a population-based study

scientific article

Differential expression of the mismatch repair gene hMSH2 in malignant prostate tissue is associated with cancer recurrence

scientific article

Differential function of Wilms' tumor gene WT1 splice isoforms in transcriptional regulation

scientific article

Digital pathology evaluation in the multicenter Nephrotic Syndrome Study Network (NEPTUNE)

scientific article

Digital pathology imaging as a novel platform for standardization and globalization of quantitative nephropathology

scientific article

Discovery and validation of candidate host DNA methylation markers for detection of cervical precancer and cancer.

scientific article published on 13 May 2017

Discovery of protein biomarkers for renal diseases

scientific article published in July 2004

Dissecting the Akt/mammalian target of rapamycin signaling network: emerging results from the head and neck cancer tissue array initiative.

scientific article published on September 2007

Downregulation of Filamin A interacting protein 1-like is associated with promoter methylation and induces an invasive phenotype in ovarian cancer.

scientific article

Dynamics of genomic and immune responses during primary immunotherapy resistance in mismatch repair-deficient tumors

scientific article published on 07 October 2020

E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium.

scientific article published on 26 April 2018

Editor's Note

scientific article published on 01 April 2017

Effect of interleukin 1 receptor antagonist gene transduction on human melanoma xenografts in nude mice

scientific article published on September 2003

Efficacy and tolerability of anti-programmed death-ligand 1 (PD-L1) antibody (Avelumab) treatment in advanced thymoma

scientific article published on 21 October 2019

Efficacy of Intralesional Botulinum Toxin A for Treatment of Painful Cutaneous Leiomyomas: A Randomized Clinical Trial.

scientific article published on 05 August 2015

Elevated expression of pancreatic adenocarcinoma upregulated factor (PAUF) is associated with poor prognosis and chemoresistance in epithelial ovarian cancer

scientific article published in Scientific Reports

Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome

scientific article

Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein

scientific article published on 18 September 2019

Estrogen receptor and progesterone receptor expression in normal terminal duct lobular units surrounding invasive breast cancer

scientific article

Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice

scientific article published in November 2003

Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation

scientific article published in March 2018

Evaluating whole slide imaging: A working group opportunity

scientific article

Evaluation environment for digital and analog pathology: a platform for validation studies

scientific article published on October 2014

Evaluation of biologic end points and pharmacokinetics in patients with metastatic breast cancer after treatment with erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor

scientific article

Evaluation of eIF4E expression in an osteosarcoma-specific tissue microarray

scientific article

Evaluation of lymphangiogenic factors, vascular endothelial growth factor D and E-cadherin in distinguishing inflammatory from locally advanced breast cancer

scientific article published on 12 June 2012

Evaluation of non-formalin tissue fixation for molecular profiling studies

scientific article published on February 2002

Evaluation of two phosphorylation sites improves the prognostic significance of Akt activation in non-small-cell lung cancer tumors

scientific article published on 5 December 2005

Expression of EIF3-p48/INT6, TID1 and Patched in cancer, a profiling of multiple tumor types and correlation of expression

scientific article published on 24 March 2007

Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients

scientific article published on 6 May 2016

Expression of heme oxygenase-1 in non-small cell lung cancer (NSCLC) and its correlation with clinical data.

scientific article

Expression of stanniocalcin 1 in thyroid side population cells and thyroid cancer cells

scientific article

Expression of stress-induced phosphoprotein1 (STIP1) is associated with tumor progression and poor prognosis in epithelial ovarian cancer.

scientific article published on February 2014

Expression of the cytoskeleton linker protein ezrin in human cancers

scientific article published on 17 March 2007

Expression of the interferon regulatory factor 8/ICSBP-1 in human reactive lymphoid tissues and B-cell lymphomas: a novel germinal center marker

scientific article

Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer.

scientific article published on 21 July 2017

Expression patterns among interferon regulatory factor-1, human X-box binding protein-1, nuclear factor kappa B, nucleophosmin, estrogen receptor-alpha and progesterone receptor proteins in breast cancer tissue microarrays.

scientific article

Extremely high Tp53 mutation load in esophageal squamous cell carcinoma in Golestan Province, Iran

scientific article

Ezrin mediates growth and survival in Ewing’s sarcoma through the AKT/mTOR, but not the MAPK, signaling pathway

scientific article published on 22 September 2006

Factors in tissue handling and processing that impact RNA obtained from formalin-fixed, paraffin-embedded tissue

scientific article published on 18 August 2008

Factors influencing the degradation of archival formalin-fixed paraffin-embedded tissue sections.

scientific article

Fascin and CK4 as biomarkers for esophageal squamous cell carcinoma ⬇️

scientific article published on March 1, 2011

Follicular lymphomas in children and young adults: a comparison of the pediatric variant with usual follicular lymphoma.

scientific article published on March 2013

Forkhead box protein O1 (FOXO1) and paired box gene 3 (PAX3) overexpression is associated with poor prognosis in patients with cervical cancer

scientific article published on 13 July 2019

Formulation and pH of the Buffered Ethanol Fixative BE70.

scientific article published in April 2017

Framework for parsing, visualizing and scoring tissue microarray images

scientific article published in April 2006

Frozen protein arrays: A new method for arraying and detecting recombinant and native tissue proteins

scientific article published on 01 November 2002

Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody

scientific article published on 11 February 2013

Functional characterization of filamin a interacting protein 1-like, a novel candidate for antivascular cancer therapy.

scientific article published on September 2008

Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer

scientific article published on 28 September 2012

Genetic variant as a selection marker for anti-prostate stem cell antigen immunotherapy of bladder cancer

scientific article published on 23 December 2012

Genomic Network-Based Analysis Reveals Pancreatic Adenocarcinoma Up-Regulating Factor-Related Prognostic Markers in Cervical Carcinoma

scientific article published on 23 October 2018

Genomic copy number alterations in clear cell renal carcinoma: associations with case characteristics and mechanisms of VHL gene inactivation

scientific article (publication date: 25 June 2012)

Global gene expression profiling and validation in esophageal squamous cell carcinoma and its association with clinical phenotypes

scientific article

Global genomic and proteomic analysis identifies biological pathways related to high-risk neuroblastoma

scientific article

Global histone H4 acetylation and HDAC2 expression in colon adenoma and carcinoma

scientific article published on 05 December 2008

Glucose transporter Glut-1 is detectable in peri-necrotic regions in many human tumor types but not normal tissues: Study using tissue microarrays

scientific article published on 24 March 2010

Glut-1 as a therapeutic target: increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies.

scientific article published on 23 May 2007

Gray zone lymphoma: chromosomal aberrations with immunophenotypic and clinical correlations.

scientific article

Greater absolute risk for all subtypes of breast cancer in the US than Malaysia.

scientific article published on 24 December 2014

H. pylori-induced apoptosis in human gastric cancer cells mediated via the release of apoptosis-inducing factor from mitochondria

scientific article

HDAC1 Upregulation by NANOG Promotes Multidrug Resistance and a Stem-like Phenotype in Immune Edited Tumor Cells.

scientific article published on 17 July 2017

HER-2 assessment in formalin-fixed paraffin-embedded breast cancer tissue by well-based reverse phase protein array

scientific article

HER3 overexpression is a prognostic indicator of extrahepatic cholangiocarcinoma.

scientific article

HSP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumors

scientific article published on 28 January 2020

Heterogeneous expression of the aquaporin 1 (AQP1) water channel in tumors of the prostate, breast, ovary, colon and lung: a study using high density multiple human tumor tissue microarrays.

scientific article published in May 2005

High throughput assessment of cells and tissues: Bayesian classification of spectral metrics from infrared vibrational spectroscopic imaging data

scientific article

High-throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium

scientific article published on 06 April 2016

Histo-proteomic profiling of formalin-fixed, paraffin-embedded tissue.

scientific article published on April 2010

Histomorphological and Molecular Assessments of the Fixation Times Comparing Formalin and Ethanol-Based Fixatives

scientific article published in November 2017

Hormonal markers in breast cancer: coexpression, relationship with pathologic characteristics, and risk factor associations in a population-based study

scientific article published on 29 October 2007

Human CCR4+ CCR6+ Th17 cells suppress autologous CD8+ T cell responses

scientific article

IGF-1 receptor signaling regulates type II pneumocyte senescence and resulting macrophage polarization in lung fibrosis

scientific article published on 29 December 2020

Identification of Candidate Genes Associated with Susceptibility to Ovarian Clear Cell Adenocarcinoma Using cis-eQTL Analysis

scientific article published on 16 April 2020

Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models

scientific article

Image microarrays (IMA): Digital pathology’s missing tool ⬇️

scientific article published on October 29, 2011

Immunoguided laser assisted microdissection techniques for DNA methylation analysis of archival tissue specimens

scientific article

Impact of preanalytic factors on the design and application of integral biomarkers for directing patient therapy

scientific article published in March 2012

Improved survival of gastric cancer with tumour Epstein-Barr virus positivity: an international pooled analysis.

scientific article

Improving the state of the science of immunohistochemistry: the Histochemical Society's standards of practice

scientific article published on August 2014

In Utero SARS-CoV-2 Infection

scientific article published on 22 October 2020

Infrared spectroscopic imaging for histopathologic recognition

scientific article published on 27 March 2005

Integrated Single-Cell Atlases Reveal an Oral SARS-CoV-2 Infection and Transmission Axis

scientific article published on 27 October 2020

Integration of architectural and cytologic driven image algorithms for prostate adenocarcinoma identification.

scientific article

Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury

article

Interstitial fibrosis scored on whole-slide digital imaging of kidney biopsies is a predictor of outcome in proteinuric glomerulopathies.

scientific article published on 27 February 2017

Intramedullary spinal cord metastasis from renal cell carcinoma: detection by positron emission tomography

scientific article published in October 2001

Intraoperative ultrasound during renal parenchymal sparing surgery for hereditary renal cancers: a 10-year experience

scientific article

Intratumoral γδ T-cell infiltrates, CCL4/5 protein expression and survival in patients with hepatocellular carcinoma

scientific article published on 05 June 2020

Intravenously administered vitamin C as cancer therapy: three cases

scientific article

LC3B upregulation by NANOG promotes immune resistance and stem-like property through hyperactivation of EGFR signaling in immune-refractory tumor cells

scientific article published on 07 August 2020

Layered expression scanning: multiplex analysis of RNA and protein gels

scientific article published on 01 December 2003

Layered expression scanning: multiplex molecular analysis of diverse life science platforms

scientific article published on 11 August 2006

Layered peptide array for multiplex immunohistochemistry

scientific article

Leveling the playing field: bringing development of biomarkers and molecular diagnostics up to the standards for drug development

scientific article published in March 2012

Liver proteomics for therapeutic drug discovery: inhibition of the cyclophilin receptor CD147 attenuates sepsis-induced acute renal failure

scientific article published on October 2007

Loss of HES-1 Expression Predicts a Poor Prognosis for Small Intestinal Adenocarcinoma Patients

scientific article published on 19 August 2020

Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility.

scientific article

Loss of antigenicity in stored sections of breast cancer tissue microarrays

scientific article published in April 2004

Loss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growth

scientific article published on 14 January 2013

Low Epstein-Barr Virus Prevalence in Cardia Gastric Cancer Among a High-Incidence Chinese Population

scientific article published on 04 May 2020

Lumen-based detection of prostate cancer via convolutional neural networks

scholarly article published 1 March 2017

MICA/B and ULBP1 NKG2D ligands are independent predictors of good prognosis in cervical cancer

scientific article

Markers and Tissue Resources for Melanoma: Meeting Report

scientific article published on 01 November 2006

Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis

scientific article published on 16 January 2020

Methylation profiling of mediastinal gray zone lymphoma reveals a distinctive signature with elements shared by classical Hodgkin's lymphoma and primary mediastinal large B-cell lymphoma

scientific article

Microarray gene expression analysis of murine tumor heterogeneity defined by dynamic contrast-enhanced MRI.

scientific article

Microscopic resolution imaging and proteomics correlation at histogeographically identical location: point by point correlation between ex vivo tissue imaging with high field MRI and multiplex tissue immunoblotting for proteomics profiling

Microvascular inflammation in renal allograft biopsies assessed by endothelial and leukocyte co-immunostain: a retrospective study on reproducibility and clinical/prognostic correlates

Microvascular inflammation in renal allograft biopsies assessed by endothelial and leukocyte co‐immunostain: a retrospective study on reproducibility and clinical/prognostic correlates

Microvessel density, expression of estrogen receptor alpha, MIB-1, p53, and c-erbB-2 in inflammatory breast cancer.

scientific article published on December 2002

Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance

scientific article published on 20 August 2018

Modeling metastasis biology and therapy in real time in the mouse lung.

scientific article

Modification of Occupational Exposures on Bladder Cancer Risk by Common Genetic Polymorphisms

scientific article

Modulation of tumor-host interactions, angiogenesis, and tumor growth by tissue inhibitor of metalloproteinase 2 via a novel mechanism

scientific article

Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF.

scientific article published on 28 October 2016

Molecular cytogenetic characterization of early and late renal cell carcinomas in von Hippel-Lindau disease

scientific article published in May 2001

Molecular pathology in epidemiologic studies: a primer on key considerations

scientific article

Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling

scientific article published on 8 June 2015

Morphology in the Digital Age: Integrating High-Resolution Description of Structural Alterations With Phenotypes and Genotypes

scientific article (publication date: May 2015)

Morphometry Predicts Early GFR Change in Primary Proteinuric Glomerulopathies: A Longitudinal Cohort Study Using Generalized Estimating Equations.

scientific article

Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19

scientific article published in 2022

Multimodal microscopy for automated histologic analysis of prostate cancer

scientific article

Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells.

scientific article

Multiple endocrine neoplasia type 1 deletion in pancreatic alpha-cells leads to development of insulinomas in mice

scientific article

Multiplex quantitative measurement of mRNAs from fixed tissue microarray sections.

scientific article

Multiview boosting digital pathology analysis of prostate cancer.

scientific article published on 22 February 2017

NAD(P)H oxidase 1, a product of differentiated colon epithelial cells, can partially replace glycoprotein 91phox in the regulated production of superoxide by phagocytes

scientific article

NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation

scientific article

Nanog signaling in cancer promotes stem-like phenotype and immune evasion

scientific article

Nematocera flies recorded in Serra do Courel, northwest Spain, May 2012 (Diptera: Anisopodidae, Blepharoceridae, Cylindrotomidae, Limoniidae, Pediciidae, Tipulidae and Trichoceridae) including descriptions of two new species of Limoniidae

scientific article (publication date: 19 January 2015)

No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication

scientific article published on 25 September 2019

Nonalcoholic fatty liver disease in spinal and bulbar muscular atrophy.

scientific article published on 15 November 2017

Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer

scientific article published on 23 June 2021

Nuclear Architecture Analysis of Prostate Cancer via Convolutional Neural Networks

scholarly article by Jin Tae Kwak & Stephen M. Hewitt published 2017 in IEEE Access

Nucleus detection using gradient orientation information and linear least squares regression

article published in 2015

Observer performance in the use of digital and optical microscopy for the interpretation of tissue-based biomarkers

scientific article

Observer variability in the interpretation of HER2/neu immunohistochemical expression with unaided and computer-aided digital microscopy

scientific article published on February 2011

Oncogene-induced senescence mediated by c-Myc requires USP10 dependent deubiquitination and stabilization of p14ARF.

scientific article published on 22 February 2018

Optimization of recovery of RNA from formalin-fixed, paraffin-embedded tissue

scientific article published in December 2006

Overexpression of CDC25B and LAMC2 mRNA and protein in esophageal squamous cell carcinomas and premalignant lesions in subjects from a high-risk population in China

scientific article published on June 2008

Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer.

scientific article published on 15 December 2009

PAX3-FOXO1 is essential for tumour initiation and maintenance but not recurrence in a human myoblast model of rhabdomyosarcoma

scientific article published on 31 January 2017

PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis

scientific article published on 17 July 2015

PLCE1 mRNA and protein expression and survival of patients with esophageal squamous cell carcinoma and gastric adenocarcinoma

scientific article

Pancreatic adenocarcinoma up-regulated factor expression is associated with disease-specific survival in cervical cancer patients.

scientific article

Paracrine SLPI secretion upregulates MMP-9 transcription and secretion in ovarian cancer cells

scientific article

Parathyroid gland-specific deletion of the mouse Men1 gene results in parathyroid neoplasia and hypercalcemic hyperparathyroidism

scientific journal article

Peak stimulated insulin secretion is associated with specific changes in gene expression profiles in sporadic insulinomas

article

Perspectives in tissue microarrays

scientific article

Pharmacodynamic assessment of histone deacetylase inhibitors: infrared vibrational spectroscopic imaging of protein acetylation

scientific article published on 24 July 2008

Phase IIA trial testing erlotinib as an intervention against intraductal pancreatic mucinous neoplasms

scientific article published in April 2011

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

scientific article published on 12 May 2020

Podoplanin Expression in Cancerous Stroma Induces Lymphangiogenesis and Predicts Lymphatic Spread and Patient Survival ⬇️

scientific article published on October 1, 2010

Polycyclic aromatic hydrocarbon exposure in oesophageal tissue and risk of oesophageal squamous cell carcinoma in north-eastern Iran

scientific article published on 28 June 2010

Polygenic risk score for the prediction of breast cancer is related to lesser terminal duct lobular unit involution of the breast

scientific article published on 07 September 2020

Post-analysis follow-up and validation of microarray experiments

scientific article

Profiling of phospho-AKT, phospho-mTOR, phospho-MAPK and EGFR in non-small cell lung cancer.

scientific article published on 31 January 2014

Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner

scientific article

Progesterone Receptor Isoform Ratio: A Breast Cancer Prognostic and Predictive Factor for Antiprogestin Responsiveness.

scientific article published on July 2017

Prognostic Significance of AMP-Dependent Kinase Alpha Expression in Cervical Cancer.

scientific article

Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry

scientific article published on 08 August 2013

Prognostic implication of SOX2 expression in small intestinal adenocarcinoma

scientific article published on 25 October 2020

Prognostic significance of annexin A2 and annexin A4 expression in patients with cervical cancer

scientific article

Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups

scientific article published on 18 October 2016

Promises and challenges of predictive tissue biomarkers

scientific article published on 01 August 2007

Protein expression of the gp78 E3 ligase predicts poor breast cancer outcome based on race

scientific article published in 2022

Proteomic expression profiling of thyroid neoplasms

scientific article published on 01 March 2007

Proteomic expressional profiling of a paraffin-embedded tissue by multiplex tissue immunoblotting

scientific article published in January 2015

Quantitative Analysis of TDLUs using Adaptive Morphological Shape Techniques

scientific article

RE: Elevated Bladder Cancer in Northern New England: The Role of Drinking Water and Arsenic

scientific article published on 14 March 2018

Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival

scientific article published on 07 January 2020

Randomized, double-blind, placebo-controlled phase IIb trial of the cyclooxygenase inhibitor ketorolac as an oral rinse in oropharyngeal leukoplakia

scientific article published in March 2004

Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1.

scientific article published on 10 February 2009

Recommendations for Improved Standardization of Immunohistochemistry

scientific article published on 01 June 2007

Recommendations for collection and handling of specimens from group breast cancer clinical trials

scientific article published on 27 October 2008

Reduced expression of FILIP1L, a novel WNT pathway inhibitor, is associated with poor survival, progression and chemoresistance in ovarian cancer.

scientific article published on 20 October 2016

Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma

scientific article published on 22 June 2013

Relation of Serum Estrogen Metabolites with Terminal Duct Lobular Unit Involution Among Women Undergoing Diagnostic Image-Guided Breast Biopsy

scientific article

Relationship between crown-like structures and sex-steroid hormones in breast adipose tissue and serum among postmenopausal breast cancer patients

scientific article published on 19 January 2017

Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma

scientific article published on 15 January 2019

Relationship of Terminal Duct Lobular Unit Involution of the Breast with Area and Volume Mammographic Densities

scientific article published on 8 December 2015

Relationships between mammographic density, tissue microvessel density, and breast biopsy diagnosis

scientific article published on 23 August 2016

Renal Tumors in the Birt-Hogg-Dubé Syndrome

article

Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group

scientific article published on 12 May 2020

Reproducibility and Feasibility of Strategies for Morphologic Assessment of Renal Biopsies Using the Nephrotic Syndrome Study Network Digital Pathology Scoring System

scientific article published on 19 February 2018

Reproducibility in the automated quantitative assessment of HER2/neu for breast cancer ⬇️

scientific article published on July 31, 2013

Reproducibility of the NEPTUNE descriptor-based scoring system on whole-slide images and histologic and ultrastructural digital images

scientific article

Reproducibility: It Is Just Good Science.

scientific article published on April 2016

Reproductive factors and risk of breast cancer by tumor subtypes among Ghanaian women: A population-based case–control study

scientific article published on 18 February 2020

Retroviral gene transfer of interferon-inducible protein 10 inhibits growth of human melanoma xenografts

scientific article

Risk of follicular lymphoma associated with BCL2 translocations in peripheral blood

scientific article published on 31 December 2014

Risk of renal and colonic neoplasms and spontaneous pneumothorax in the Birt-Hogg-Dubé syndrome.

scientific article

SARS-CoV-2 infection and persistence in the human body and brain at autopsy

scientific article published on 14 December 2022

Schedule-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation, angiogenesis, and tumor growth by topotecan in U251-HRE glioblastoma xenografts

scientific article

Scoring of tumor-infiltrating lymphocytes: From visual estimation to machine learning

scholarly article by F Klauschen et al published October 2018 in Seminars in Cancer Biology

Screening a panel of drugs with diverse mechanisms of action yields potential therapeutic agents against neuroblastoma

scientific article

Sepsis-induced organ failure is mediated by different pathways in the kidney and liver: acute renal failure is dependent on MyD88 but not renal cell apoptosis.

scientific article published on March 2006

Sil overexpression in lung cancer characterizes tumors with increased mitotic activity

scientific article

Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging

scientific article published in 2021

Specimen Morcellation after Laparoscopic Radical Nephrectomy: Confirmation of Histologic Diagnosis Using Needle Biopsy

scientific article published on 01 March 2002

Spectrum of activity and molecular correlates of response to phosphatidylinositol ether lipid analogues, novel lipid-based inhibitors of Akt.

scientific article published on March 2006

Sperm-derived SPANX-B is a clinically relevant tumor antigen that is expressed in human tumors and readily recognized by human CD4+ and CD8+ T cells

scientific article published on 10 March 2009

Sporadic naturally occurring melanoma in dogs as a preclinical model for human melanoma

scientific article

Standardized measures of lobular involution and subsequent breast cancer risk among women with benign breast disease: a nested case-control study

scientific article published on 3 August 2016

Synaptonemal complex protein 3 as a novel prognostic marker in early stage non-small cell lung cancer

scientific article published on 12 October 2012

Synaptonemal complex protein 3 is a prognostic marker in cervical cancer

scientific article

Synaptonemal complex protein 3 is associated with lymphangiogenesis in non-small cell lung cancer patients with lymph node metastasis.

scientific article

Systematic proteome analysis identifies transcription factor YY1 as a direct target of miR-34a

scientific article published on 23 December 2010

Targeting Cyclin D-CDK4/6 sensitizes immune-refractory cancer by blocking the SCP3-NANOG axis

scientific article published on 6 February 2018

Targeting a Cancer-Specific Epitope of the Epidermal Growth Factor Receptor in Triple-Negative Breast Cancer.

scientific article published on 13 April 2016

Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses

scientific article published on 5 December 2012

Terminal duct lobular unit involution of the normal breast: implications for breast cancer etiology

scientific article

The 19q12 bladder cancer GWAS signal: association with cyclin E function and aggressive disease

scientific article published in October 2014

The Angiogenesis Inhibitor, Endostatin, Does Not Affect Murine Cutaneous Wound Healing

article

The Application of Digital Pathology to Improve Accuracy in Glomerular Enumeration in Renal Biopsies

scientific article

The Evolution of Pre-analytic Factors in Anatomic Pathology

scientific article published on 01 January 2015

The Impact Factor Is a 20th-Century Relic in an Electronic Journal World of Instant Citation Counts.

scientific article published in July 2017

The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl

scientific article published on 12 January 2016

The actin-cytoskeleton linker protein ezrin is regulated during osteosarcoma metastasis by PKC.

scientific article

The anti-cancer effects of itraconazole in epithelial ovarian cancer

scientific article

The application of tissue microarrays in the validation of microarray results

scientific article published on January 2006

The chemokine CXCL16 and its receptor, CXCR6, as markers and promoters of inflammation-associated cancers

scientific article

The cocaine- and amphetamine-regulated transcript mediates ligand-independent activation of ERα, and is an independent prognostic factor in node-negative breast cancer.

scientific article

The expression of phospho-AKT, phospho-mTOR, and PTEN in extrahepatic cholangiocarcinoma.

scientific article published in January 2009

The influence of DNA repair on neurological degeneration, cachexia, skin cancer and internal neoplasms: autopsy report of four xeroderma pigmentosum patients (XP-A, XP-C and XP-D).

scientific article published on 08 May 2013

The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

scientific article published on 4 January 2004

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

scientific article

The paraffin-embedded RNA metric (PERM) for RNA isolated from formalin-fixed, paraffin-embedded tissue.

scientific article

The path to a better biomarker: Application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice

scientific article published on 04 March 2020

The role of S100A14 in epithelial ovarian tumors.

scientific article

The role of interleukin 1 in growth and metastasis of human cancer xenografts

scientific article published on February 2006

The role of secreted frizzled-related protein 2 expression in prostate cancer.

scientific article

The syrphids of Serra do Courel, Northern Spain and description of a new Cheilosia Meigen species (Diptera: Syrphidae)

scientific article (publication date: May 2014)

The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation

scientific article published on 25 November 2007

Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma.

scientific article published on 24 July 2017

Time Advances, People and Language Change, but the Fundamentals Remain the Same

scientific article published on January 2016

Tissue Microarrays as a Tool in the Discovery and Validation of Predictive Biomarkers ⬇️

scientific article published on January 1, 2012

Tissue microarray analysis of human FRAT1 expression and its correlation with the subcellular localisation of beta-catenin in ovarian tumours

scientific article

Tissue microarrays as a platform for proteomic investigation

scientific article published on 05 September 2006

Tissue microarrays as a tool in the discovery and validation of tumor markers

scientific article published on January 2009

Tissue microarrays enabling high-throughput molecular pathology.

scientific article published on 20 July 2007

Tissue microarrays: bridging the gap between research and the clinic

scientific article

Tissues from population-based cancer registries: a novel approach to increasing research potential

scientific article published in July 2005

Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells

scientific article published on 07 March 2019

Transactivation of the EGFR by AP-1 is induced by Helicobacter pylori in gastric cancer

scientific article

Transcriptional silencer of the Wilms' tumor gene WT1 contains an Alu repeat

scientific article published on July 1995

Transfer and Multiplex Immunoblotting of a Paraffin Embedded Tissue

scientific article published on 01 January 2009

Transfer and multiplex immunoblotting of a paraffin embedded tissue

scientific article published in February 2006

Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer

scientific article published on 03 October 2019

Tumor vasculature-targeted delivery of tumor necrosis factor-alpha

scientific article

Tumor-associated macrophage, angiogenesis and lymphangiogenesis markers predict prognosis of non-small cell lung cancer patients

scientific article published on 23 November 2020

Ultrastructural Characterization of Proteinuric Patients Predicts Clinical Outcomes

scientific article published on 21 February 2020

Uncertainty in the assessment of immunohistochemical staining with optical and digital microscopy: lessons from a reader study

Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the International Immuno-Oncology Biomarker Working Group o

article by Maria Vittoria Dieci et al published October 2018 in Seminars in Cancer Biology

Using Digital Pathology to Understand Epithelial Characteristics of Benign Breast Disease among Women Undergoing Diagnostic Image-Guided Breast Biopsy

scientific article published on 23 October 2019

Utilization of microdissection and the polymerase chain reaction for the diagnosis of adrenal cortical carcinoma in fine-needle aspiration cytology

scientific article published on August 1999

Validation of esophageal squamous cell carcinoma candidate genes from high-throughput transcriptomic studies

scientific article published on 14 August 2013

Validation of proteomic-based discovery with tissue microarrays

scientific article published on 26 August 2008

Variation in breast cancer hormone receptor andHER2levels by etiologic factors: A population-based analysis

article

Vitamin C pharmacokinetics: implications for oral and intravenous use.

scientific article

What Measures Should Biobankers Employ to Prevent Possible Glitches in Storage Technology?

scientific article published on 01 August 2012

What are the most oppressing legal and ethical issues facing biorepositories and what are some strategies to address them?

scientific article

Wilms tumor-1, claudin-1 and ezrin are useful immunohistochemical markers that help to distinguish schwannoma from fibroblastic meningioma

scientific article published on 10 September 2011

eeDAP: An Evaluation Environment for Digital and Analog Pathology

scientific article

mTOR as a molecular target in HPV-associated oral and cervical squamous carcinomas

scientific article

microRNA alterations driving acute and late stages of radiation-induced fibrosis in a murine skin model

scientific article

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