List of works - Aung Pyae Phyo

A major genome region underlying artemisinin resistance in malaria

scientific article

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

scientific article published on 24 February 2021

An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia

scientific article

Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria

scientific article

Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial

scientific article

Artemisinin Resistance in Plasmodium falciparum Malaria

scientific article

Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response

scientific article published on 28 March 2022

Artemisinin-Resistant Plasmodium falciparum K13 Mutant Alleles, Thailand-Myanmar Border

scientific article published on August 2016

Artesunate/dihydroartemisinin pharmacokinetics in acute falciparum malaria in pregnancy: absorption, bioavailability, disposition and disease effects.

scientific article

Auditory assessment of patients with acute uncomplicated Plasmodium falciparum malaria treated with three-day mefloquine-artesunate on the north-western border of Thailand

scientific article

Case Report: A case report of multiple co-infections (melioidosis, paragonimiasis, Covid-19 and tuberculosis) in a patient with diabetes mellitus and thalassemia-trait in Myanmar

scientific article published in 2022

Challenges to replace ACT as first-line drug

scientific article published on 24 July 2017

Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment

scientific article published in 2009

Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand ⬇️

scientific article

Combating multidrug-resistant Plasmodium falciparum malaria

scientific article published on 5 June 2017

Correction: An Open-Label, Randomised Study of Dihydroartemisinin-Piperaquine Versus Artesunate-Mefloquine for Falciparum Malaria in Asia

scientific article published in PLoS ONE

Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai-Myanmar Border (2003-2013): The Role of Parasite Genetic Factors

scientific article published on 16 June 2016

Declining Transmission and Immunity to Malaria and Emerging Artemisinin Resistance in Thailand: A Longitudinal Study

scientific article published on September 2017

Defining the in vivo phenotype of artemisinin-resistant falciparum malaria: a modelling approach

scientific article

Dihydroartemisinin-piperaquine versus chloroquine in the treatment of Plasmodium vivax malaria in Thailand: a randomized controlled trial

scientific article

Effect of early detection and treatment on malaria related maternal mortality on the north-western border of Thailand 1986-2010.

scientific article

Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria

scientific article published on 21 November 2012

Effective and cheap removal of leukocytes and platelets from Plasmodium vivax infected blood

scientific article published on 02 June 2009

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

scientific article

Evaluation of the forum theatre approach for public engagement around antibiotic use in Myanmar

scientific article published on 09 July 2020

Gametocyte dynamics and the role of drugs in reducing the transmission potential of Plasmodium vivax

scientific article

Genetic architecture of artemisinin-resistant Plasmodium falciparum

scientific article (publication date: March 2015)

Genetic evaluation of the performance of malaria parasite clearance rate metrics

scientific article published on 16 April 2013

Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia

scientific article published on 17 December 2012

Genomic epidemiology of the current wave of artemisinin resistant malaria

scholarly article by Roberto Amato et al published 22 May 2015 in bioRxiv

Haemolysis in G6PD Heterozygous Females Treated with Primaquine for Plasmodium vivax Malaria: A Nested Cohort in a Trial of Radical Curative Regimens.

scientific article

Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia

scientific article

Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance

scientific article (publication date: 28 April 2017)

Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance in western Thailand

scientific article published on 2 November 2016

Malaria

scholarly article by Woodrow and Phyo published in The Lancet

Malaria burden and artemisinin resistance in the mobile and migrant population on the Thai-Myanmar border, 1999-2011: an observational study

scientific article

Malaria in the post-partum period; a prospective cohort study

scientific article

Methotrexate is highly potent against pyrimethamine-resistant Plasmodium vivax ⬇️

scientific article

Opposite malaria and pregnancy effect on oral bioavailability of artesunate - a population pharmacokinetic evaluation

scientific article

Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives

scientific article

Pharmacokinetics of amodiaquine and desethylamodiaquine in pregnant and postpartum women with Plasmodium vivax malaria

scientific article

Pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated falciparum malaria

scientific article published on 26 September 2011

Plasmodium falciparum Kelch 13 mutations and treatment response in patients in Hpa-Pun District, Northern Kayin State, Myanmar

scientific article published on 25 November 2017

Pooled sequencing and rare variant association tests for identifying the determinants of emerging drug resistance in malaria parasites

scientific article

Poor response to artesunate treatment in two patients with severe malaria on the Thai-Myanmar border

scientific article published on 15 January 2018

Population Parameters Underlying an Ongoing Soft Sweep in Southeast Asian Malaria Parasites

scientific article published on 20 October 2016

Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis.

scientific article

Population Pharmacokinetic and Pharmacodynamic Modeling of Artemisinin Resistance in Southeast Asia

scientific article published on 11 September 2017

Population genetic correlates of declining transmission in a human pathogen

scientific article published on 2 November 2012

Population pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated malaria

scientific article published on 17 January 2012

Pyronaridine-artesunate versus chloroquine in patients with acute Plasmodium vivax malaria: a randomized, double-blind, non-inferiority trial

scientific article

Pyronaridine-artesunate versus mefloquine plus artesunate for malaria

scientific article published in April 2012

Quantifying connectivity between local Plasmodium falciparum malaria parasite populations using identity by descent.

scientific article published on 27 October 2017

Randomized, double-blind, placebo-controlled trial of monthly versus bimonthly dihydroartemisinin-piperaquine chemoprevention in adults at high risk of malaria

scientific article published on 17 January 2012

Reply to Meshnick and Hastings et al

scientific article

Spiroindolone KAE609 for falciparum and vivax malaria

scientific article

Spread of artemisinin resistance in Plasmodium falciparum malaria

scientific article published on 31 July 2014

The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: A systematic review and individual patient data meta-analysis

scientific article published on 04 October 2019

The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network

scientific article published on 19 November 2020

The role of point-of-care tests in antibiotic stewardship for urinary tract infections in a resource-limited setting on the Thailand-Myanmar border

scientific article published on 11 May 2015

Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial

scientific article published on 11 March 2020

Two fatal cases of melioidosis on the Thai-Myanmar border

scientific article published on 06 January 2014

Why are there so many independent origins of artemisinin resistance in malaria parasites?

scientific article published on 31 May 2016

List of works by Aung Pyae Phyo

A major genome region underlying artemisinin resistance in malaria

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia

Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria

Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial

Artemisinin Resistance in Plasmodium falciparum Malaria

Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response

Artemisinin-Resistant Plasmodium falciparum K13 Mutant Alleles, Thailand-Myanmar Border

Artesunate/dihydroartemisinin pharmacokinetics in acute falciparum malaria in pregnancy: absorption, bioavailability, disposition and disease effects.

Auditory assessment of patients with acute uncomplicated Plasmodium falciparum malaria treated with three-day mefloquine-artesunate on the north-western border of Thailand

Case Report: A case report of multiple co-infections (melioidosis, paragonimiasis, Covid-19 and tuberculosis) in a patient with diabetes mellitus and thalassemia-trait in Myanmar

Challenges to replace ACT as first-line drug

Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment

Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand ⬇️

Combating multidrug-resistant Plasmodium falciparum malaria

Correction: An Open-Label, Randomised Study of Dihydroartemisinin-Piperaquine Versus Artesunate-Mefloquine for Falciparum Malaria in Asia

Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai-Myanmar Border (2003-2013): The Role of Parasite Genetic Factors

Declining Transmission and Immunity to Malaria and Emerging Artemisinin Resistance in Thailand: A Longitudinal Study

Defining the in vivo phenotype of artemisinin-resistant falciparum malaria: a modelling approach

Dihydroartemisinin-piperaquine versus chloroquine in the treatment of Plasmodium vivax malaria in Thailand: a randomized controlled trial

Effect of early detection and treatment on malaria related maternal mortality on the north-western border of Thailand 1986-2010.

Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria

Effective and cheap removal of leukocytes and platelets from Plasmodium vivax infected blood

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

Evaluation of the forum theatre approach for public engagement around antibiotic use in Myanmar

Gametocyte dynamics and the role of drugs in reducing the transmission potential of Plasmodium vivax

Genetic architecture of artemisinin-resistant Plasmodium falciparum

Genetic evaluation of the performance of malaria parasite clearance rate metrics

Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia

Genomic epidemiology of the current wave of artemisinin resistant malaria

Haemolysis in G6PD Heterozygous Females Treated with Primaquine for Plasmodium vivax Malaria: A Nested Cohort in a Trial of Radical Curative Regimens.

Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia

Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance

Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance in western Thailand

Malaria

Malaria burden and artemisinin resistance in the mobile and migrant population on the Thai-Myanmar border, 1999-2011: an observational study

Malaria in the post-partum period; a prospective cohort study

Methotrexate is highly potent against pyrimethamine-resistant Plasmodium vivax ⬇️

Opposite malaria and pregnancy effect on oral bioavailability of artesunate - a population pharmacokinetic evaluation

Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives

Pharmacokinetics of amodiaquine and desethylamodiaquine in pregnant and postpartum women with Plasmodium vivax malaria

Pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated falciparum malaria

Plasmodium falciparum Kelch 13 mutations and treatment response in patients in Hpa-Pun District, Northern Kayin State, Myanmar

Pooled sequencing and rare variant association tests for identifying the determinants of emerging drug resistance in malaria parasites

Poor response to artesunate treatment in two patients with severe malaria on the Thai-Myanmar border

Population Parameters Underlying an Ongoing Soft Sweep in Southeast Asian Malaria Parasites

Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis.

Population Pharmacokinetic and Pharmacodynamic Modeling of Artemisinin Resistance in Southeast Asia

Population genetic correlates of declining transmission in a human pathogen

Population pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated malaria

Pyronaridine-artesunate versus chloroquine in patients with acute Plasmodium vivax malaria: a randomized, double-blind, non-inferiority trial

Pyronaridine-artesunate versus mefloquine plus artesunate for malaria

Quantifying connectivity between local Plasmodium falciparum malaria parasite populations using identity by descent.

Randomized, double-blind, placebo-controlled trial of monthly versus bimonthly dihydroartemisinin-piperaquine chemoprevention in adults at high risk of malaria

Reply to Meshnick and Hastings et al

Spiroindolone KAE609 for falciparum and vivax malaria

Spread of artemisinin resistance in Plasmodium falciparum malaria

The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: A systematic review and individual patient data meta-analysis

The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network

The role of point-of-care tests in antibiotic stewardship for urinary tract infections in a resource-limited setting on the Thailand-Myanmar border

Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial

Two fatal cases of melioidosis on the Thai-Myanmar border

Why are there so many independent origins of artemisinin resistance in malaria parasites?