List of works - Klemens Ruprecht

A blood based 12-miRNA signature of Alzheimer disease patients

scientific article

A novel human polyomavirus closely related to the african green monkey-derived lymphotropic polyomavirus

scientific article

An N-terminally truncated envelope protein encoded by a human endogenous retrovirus W locus on chromosome Xq22.3.

scientific article

Analysis of Lymphocytic DNA Damage in Early Multiple Sclerosis by Automated Gamma-H2AX and 53BP1 Foci Detection: A Case Control Study

scientific article published on 28 January 2016

Analysis of transcribed human endogenous retrovirus W env loci clarifies the origin of multiple sclerosis-associated retrovirus env sequences

scientific article

Anti-MOG antibody-associated disorders: differences in clinical profiles and prognosis in Japan and Germany

scientific article published on 20 November 2020

Anti-NMDAR encephalitis mimicking HaNDL syndrome

scientific article published on 11 March 2014

Aquaporin-4 antibody testing: direct comparison of M1-AQP4-DNA-transfected cells with leaky scanning versus M23-AQP4-DNA-transfected cells as antigenic substrate

scientific article

Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance

scientific article

Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis

scientific article published on 05 May 2020

Comprehensive analysis of human endogenous retrovirus group HERV-W locus transcription in multiple sclerosis brain lesions by high-throughput amplicon sequencing

scientific article published on 09 October 2013

Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

scientific article published in 2012

Contribution of blood vessels to retinal nerve fiber layer thickness in NMOSD.

scientific article

Epstein-Barr virus antibodies in serum and DNA load in saliva are not associated with radiological or clinical disease activity in patients with early multiple sclerosis

scientific article

Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis

scientific article published on 09 March 2017

Favorable outcome of interferon-beta associated thrombotic microangiopathy following treatment with corticosteroids, plasma exchange and rituximab: A case report

scientific article

Female hormonal exposures and neuromyelitis optica symptom onset in a multicenter study

scientific article published on 24 March 2017

Glioblastoma multiforme with oligodendroglial component (GBMO): favorable outcome after post-operative radiotherapy and chemotherapy with nimustine (ACNU) and teniposide (VM26)

scientific article

Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease.

scientific article published on 28 March 2012

Hypofractionated stereotactic re-irradiation: treatment option in recurrent malignant glioma

scientific article

Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response

scientific article published on June 2017

Importance of cerebrospinal fluid analysis in the era of McDonald 2010 criteria: a German-Austrian retrospective multicenter study in patients with a clinically isolated syndrome

scientific article published on 11 October 2016

Insufficient treatment of severe depression in neuromyelitis optica spectrum disorder

scientific article published on 24 October 2016

Interaction of human immunodeficiency virus gp120 with the voltage-gated potassium channel BEC1

scientific article

Intrathecal immunoglobulin A and G antibodies to synapsin in a patient with limbic encephalitis.

scientific article published on 4 November 2015

Low intrathecal antibody production despite high seroprevalence of Epstein-Barr virus in multiple sclerosis: a review of the literature

scientific article published on 2 November 2017

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin.

scientific article published on 26 September 2016

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome

scientific article

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome

scientific article

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients

scientific article

MRI phase changes in multiple sclerosis vs neuromyelitis optica lesions at 7T

scientific article published on 22 July 2016

Magnetic Resonance Phase Alterations in Multiple Sclerosis Patients with Short and Long Disease Duration.

scientific article published on 17 July 2015

Measles IgG Antibody Index Correlates with T2 Lesion Load on MRI in Patients with Early Multiple Sclerosis ⬇️

scientific article published on January 19, 2012

Microstructural visual system changes in AQP4-antibody-seropositive NMOSD.

scientific article published on 22 February 2017

Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls

scientific article

Multiple sclerosis: modulation of toll-like receptor (TLR) expression by interferon-β includes upregulation of TLR7 in plasmacytoid dendritic cells

scientific article

Myasthenia gravis: analysis of serum autoantibody reactivities to 1827 potential human autoantigens by protein macroarrays

scientific article

Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses

scientific article

Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis

scientific article published on 31 October 2015

Olfactory dysfunction in patients with primary progressive MS.

scientific article

Optic neuritis is associated with inner nuclear layer thickening and microcystic macular edema independently of multiple sclerosis

scientific article

Optical Coherence Tomography Reveals Distinct Patterns of Retinal Damage in Neuromyelitis Optica and Multiple Sclerosis

scientific article

Prioritizing and selecting likely novel miRNAs from NGS data.

scientific article published on 3 December 2015

Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: Emergence of new molecular targets ⬇️

scientific article published on October 1, 2012

Relations of low contrast visual acuity, quality of life and multiple sclerosis functional composite: a cross-sectional analysis

scientific article

Screening for MOG-IgG and 27 other anti-glial and anti-neuronal autoantibodies in 'pattern II multiple sclerosis' and brain biopsy findings in a MOG-IgG-positive case.

scientific article

Serological profiling of the EBV immune response in Chronic Fatigue Syndrome using a peptide microarray

scientific article

Serum peptide reactivities may distinguish neuromyelitis optica subgroups and multiple sclerosis

scientific article published on 2 February 2016

The fraction of varicella zoster virus-specific antibodies among all intrathecally-produced antibodies discriminates between patients with varicella zoster virus reactivation and multiple sclerosis

scientific article published on 12 February 2014

Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica

scientific article published on 05 June 2020

Update on biomarkers in neuromyelitis optica

scientific article (publication date: August 2015)

Widespread inflammation in CLIPPERS syndrome indicated by autopsy and ultra-high-field 7T MRI

scientific article published on 20 April 2016

miFRame: analysis and visualization of miRNA sequencing data in neurological disorders

scientific article published on 14 July 2015

List of works by Klemens Ruprecht

A blood based 12-miRNA signature of Alzheimer disease patients

A novel human polyomavirus closely related to the african green monkey-derived lymphotropic polyomavirus

An N-terminally truncated envelope protein encoded by a human endogenous retrovirus W locus on chromosome Xq22.3.

Analysis of Lymphocytic DNA Damage in Early Multiple Sclerosis by Automated Gamma-H2AX and 53BP1 Foci Detection: A Case Control Study

Analysis of transcribed human endogenous retrovirus W env loci clarifies the origin of multiple sclerosis-associated retrovirus env sequences

Anti-MOG antibody-associated disorders: differences in clinical profiles and prognosis in Japan and Germany

Anti-NMDAR encephalitis mimicking HaNDL syndrome

Aquaporin-4 antibody testing: direct comparison of M1-AQP4-DNA-transfected cells with leaky scanning versus M23-AQP4-DNA-transfected cells as antigenic substrate

Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance

Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis

Comprehensive analysis of human endogenous retrovirus group HERV-W locus transcription in multiple sclerosis brain lesions by high-throughput amplicon sequencing

Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

Contribution of blood vessels to retinal nerve fiber layer thickness in NMOSD.

Epstein-Barr virus antibodies in serum and DNA load in saliva are not associated with radiological or clinical disease activity in patients with early multiple sclerosis

Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis

Favorable outcome of interferon-beta associated thrombotic microangiopathy following treatment with corticosteroids, plasma exchange and rituximab: A case report

Female hormonal exposures and neuromyelitis optica symptom onset in a multicenter study

Glioblastoma multiforme with oligodendroglial component (GBMO): favorable outcome after post-operative radiotherapy and chemotherapy with nimustine (ACNU) and teniposide (VM26)

Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease.

Hypofractionated stereotactic re-irradiation: treatment option in recurrent malignant glioma

Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response

Importance of cerebrospinal fluid analysis in the era of McDonald 2010 criteria: a German-Austrian retrospective multicenter study in patients with a clinically isolated syndrome

Insufficient treatment of severe depression in neuromyelitis optica spectrum disorder

Interaction of human immunodeficiency virus gp120 with the voltage-gated potassium channel BEC1

Intrathecal immunoglobulin A and G antibodies to synapsin in a patient with limbic encephalitis.

Low intrathecal antibody production despite high seroprevalence of Epstein-Barr virus in multiple sclerosis: a review of the literature

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin.

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients

MRI phase changes in multiple sclerosis vs neuromyelitis optica lesions at 7T

Magnetic Resonance Phase Alterations in Multiple Sclerosis Patients with Short and Long Disease Duration.

Measles IgG Antibody Index Correlates with T2 Lesion Load on MRI in Patients with Early Multiple Sclerosis ⬇️

Microstructural visual system changes in AQP4-antibody-seropositive NMOSD.

Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls

Multiple sclerosis: modulation of toll-like receptor (TLR) expression by interferon-β includes upregulation of TLR7 in plasmacytoid dendritic cells

Myasthenia gravis: analysis of serum autoantibody reactivities to 1827 potential human autoantigens by protein macroarrays

Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses

Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis

Olfactory dysfunction in patients with primary progressive MS.

Optic neuritis is associated with inner nuclear layer thickening and microcystic macular edema independently of multiple sclerosis

Optical Coherence Tomography Reveals Distinct Patterns of Retinal Damage in Neuromyelitis Optica and Multiple Sclerosis

Prioritizing and selecting likely novel miRNAs from NGS data.

Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: Emergence of new molecular targets ⬇️

Relations of low contrast visual acuity, quality of life and multiple sclerosis functional composite: a cross-sectional analysis

Screening for MOG-IgG and 27 other anti-glial and anti-neuronal autoantibodies in 'pattern II multiple sclerosis' and brain biopsy findings in a MOG-IgG-positive case.

Serological profiling of the EBV immune response in Chronic Fatigue Syndrome using a peptide microarray

Serum peptide reactivities may distinguish neuromyelitis optica subgroups and multiple sclerosis

The fraction of varicella zoster virus-specific antibodies among all intrathecally-produced antibodies discriminates between patients with varicella zoster virus reactivation and multiple sclerosis

Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica

Update on biomarkers in neuromyelitis optica

Widespread inflammation in CLIPPERS syndrome indicated by autopsy and ultra-high-field 7T MRI

miFRame: analysis and visualization of miRNA sequencing data in neurological disorders