List of works - Orhan Aktas

Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system

scientific article

Activation of microglial poly(ADP-ribose)-polymerase-1 by cholesterol breakdown products during neuroinflammation: a link between demyelination and neuronal damage

scientific article

Acute sarcoidosis in a multiple sclerosis patient after alemtuzumab treatment

scientific article published on 11 October 2018

Advances in and Algorithms for the Treatment of Relapsing-Remitting Multiple Sclerosis

scientific article

An emboligenic pulmonary abscess leading to ischemic stroke and secondary brain abscess.

scientific article

Antibody to aquaporin 4 in the diagnosis of neuromyelitis optica

scientific article

Apheresis therapies for NMOSD attacks: A retrospective study of 207 therapeutic interventions

Aquaporin-4 antibodies in patients treated with natalizumab for suspected MS.

scientific article

Aquaporin-4 antibody testing: direct comparison of M1-AQP4-DNA-transfected cells with leaky scanning versus M23-AQP4-DNA-transfected cells as antigenic substrate

scientific article

Author response: Longitudinal optic neuritis-unrelated visual evoked potential changes in NMO spectrum disorders

scientific article published on 01 September 2020

COVID-19 and management of neuroimmunological disorders

scientific article published on 22 May 2020

Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients

scientific article published on 03 September 2020

Cladribine as a therapeutic option in multiple sclerosis ⬇️

scientific article published on June 1, 2011

Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium

scientific article published on 30 October 2020

Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

scientific article published in 2012

Death ligands and autoimmune demyelination

scientific article published on August 2006

Demyelination reduces brain parenchymal stiffness quantified in vivo by magnetic resonance elastography.

scientific article published on 5 April 2012

Development of oral cladribine for the treatment of multiple sclerosis

scientific article

Diagnostic criteria for Susac syndrome

scientific article

Disease amelioration with tocilizumab in a treatment-resistant patient with neuromyelitis optica: implication for cellular immune responses

scientific article

Efficacy of glatiramer acetate in neuromyelitis optica spectrum disorder: a multicenter retrospective study

scientific article published on 25 January 2016

Electrostatically Stabilized Magnetic Nanoparticles - An Optimized Protocol to Label Murine T Cells for in vivo MRI

scientific article published on 16 December 2011

Epigallocatechin Gallate in Relapsing-Remitting Multiple Sclerosis

scientific article published in 2021

Factors associated with headache in intravenous immunoglobulin treatment for neurological diseases

scientific article published on 23 July 2019

Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1.

scientific article

Green tea epigallocatechin-3-gallate mediates T cellular NF-kappa B inhibition and exerts neuroprotection in autoimmune encephalomyelitis

scientific article

IFNβ secreted by microglia mediates clearance of myelin debris in CNS autoimmunity

scientific article

Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress

scientific article

Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response

scientific article published on June 2017

Impact of HMG-CoA reductase inhibition on brain pathology

scientific article published on 15 June 2007

Influence of female sex and fertile age on neuromyelitis optica spectrum disorders

scientific article

Interferon beta-1a sc at 25 years: a mainstay in the treatment of multiple sclerosis over the period of one generation

scientific article published in 2023

Interferon-β-related tumefactive brain lesion in a Caucasian patient with neuromyelitis optica and clinical stabilization with tocilizumab

scientific article

Is It Too Early to Predict the Failure of Natalizumab in NMO?—Reply

Lack of tumor necrosis factor-related apoptosis-inducing ligand but presence of its receptors in the human brain

scientific article (publication date: 15 February 2002)

Long-term Therapy With Interleukin 6 Receptor Blockade in Highly Active Neuromyelitis Optica Spectrum Disorder

scientific article published on July 2015

Longitudinal optic neuritis-unrelated visual evoked potential changes in NMO spectrum disorders

scientific article published on 03 December 2019

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin.

scientific article published on 26 September 2016

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome

scientific article

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome

scientific article

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients

scientific article

Natalizumab restores aberrant miRNA expression profile in multiple sclerosis and reveals a critical role for miR-20b

scientific article

Neurodegeneration in autoimmune demyelination: recent mechanistic insights reveal novel therapeutic targets

scientific article published on 10 January 2007

Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses

scientific article

Neuronal damage in brain inflammation

scientific article published on February 2007

Neuroprotective effect of combination therapy of glatiramer acetate and epigallocatechin-3-gallate in neuroinflammation

scientific article

Optical coherence tomography in parkinsonian syndromes

scientific article

Oral high-dose atorvastatin treatment in relapsing-remitting multiple sclerosis

scientific article

Patterns of retinal damage facilitate differential diagnosis between Susac syndrome and MS.

scientific article

Pneumococcal meningitis and vaccine effects in the era of conjugate vaccination: results of 20 years of nationwide surveillance in Germany

scientific article

Premature aging of the hippocampal neurogenic niche in adult Bmal1-deficient mice

scientific article published in June 2015

Progressive change in primary progressive multiple sclerosis normal-appearing white matter: a serial diffusion magnetic resonance imaging study

scientific article

Regulation of self-reactive T cells by human immunoglobulins--implications for multiple sclerosis therapy

scientific article

Retinal Neurodegeneration in Wilson’s Disease Revealed by Spectral Domain Optical Coherence Tomography ⬇️

scientific article published on November 16, 2012

Retinal inner nuclear layer volume reflects inflammatory disease activity in multiple sclerosis; a longitudinal OCT study

scientific article published on 01 July 2019

Retinal pathology in idiopathic moyamoya angiopathy detected by optical coherence tomography

scientific article published on 15 July 2015

Serum neurofilament light chain: No clear relation to cognition and neuropsychiatric symptoms in stable MS

scientific article published on 24 September 2020

Serum peptide reactivities may distinguish neuromyelitis optica subgroups and multiple sclerosis

scientific article published on 2 February 2016

Targeting B Cells to Modify MS, NMOSD, and MOGAD: Part 1

scientific article published on 16 December 2020

Targeting B cells to modify MS, NMOSD, and MOGAD: Part 2

scientific article published on 16 December 2020

The Rare IL22RA2 Signal Peptide Coding Variant rs28385692 Decreases Secretion of IL-22BP Isoform-1, -2 and -3 and Is Associated with Risk for Multiple Sclerosis

scientific article published on 10 January 2020

The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases

scientific article published on August 2006

The role of TRAIL/TRAIL receptors in central nervous system pathology

scientific article published on May 2007

Treatment of optic neuritis with erythropoietin (TONE): a randomised, double-blind, placebo-controlled trial-study protocol

scientific article published on March 2016

Treatment of relapsing paralysis in experimental encephalomyelitis by targeting Th1 cells through atorvastatin

scientific article

Update on biomarkers in neuromyelitis optica

scientific article (publication date: August 2015)

Update on the diagnosis and treatment of neuromyelitis optica: recommendations of the Neuromyelitis Optica Study Group (NEMOS).

scientific article

Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder

scientific article

Very late-onset neuromyelitis optica spectrum disorder beyond the age of 75.

scientific article published on 10 May 2015

Visual evoked potentials in neuromyelitis optica and its spectrum disorders

scientific article published on 5 September 2013

List of works by Orhan Aktas

Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system

Activation of microglial poly(ADP-ribose)-polymerase-1 by cholesterol breakdown products during neuroinflammation: a link between demyelination and neuronal damage

Acute sarcoidosis in a multiple sclerosis patient after alemtuzumab treatment

Advances in and Algorithms for the Treatment of Relapsing-Remitting Multiple Sclerosis

An emboligenic pulmonary abscess leading to ischemic stroke and secondary brain abscess.

Antibody to aquaporin 4 in the diagnosis of neuromyelitis optica

Apheresis therapies for NMOSD attacks: A retrospective study of 207 therapeutic interventions

Aquaporin-4 antibodies in patients treated with natalizumab for suspected MS.

Aquaporin-4 antibody testing: direct comparison of M1-AQP4-DNA-transfected cells with leaky scanning versus M23-AQP4-DNA-transfected cells as antigenic substrate

Author response: Longitudinal optic neuritis-unrelated visual evoked potential changes in NMO spectrum disorders

COVID-19 and management of neuroimmunological disorders

Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients

Cladribine as a therapeutic option in multiple sclerosis ⬇️

Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium

Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

Death ligands and autoimmune demyelination

Demyelination reduces brain parenchymal stiffness quantified in vivo by magnetic resonance elastography.

Development of oral cladribine for the treatment of multiple sclerosis

Diagnostic criteria for Susac syndrome

Disease amelioration with tocilizumab in a treatment-resistant patient with neuromyelitis optica: implication for cellular immune responses

Efficacy of glatiramer acetate in neuromyelitis optica spectrum disorder: a multicenter retrospective study

Electrostatically Stabilized Magnetic Nanoparticles - An Optimized Protocol to Label Murine T Cells for in vivo MRI

Epigallocatechin Gallate in Relapsing-Remitting Multiple Sclerosis

Factors associated with headache in intravenous immunoglobulin treatment for neurological diseases

Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1.

Green tea epigallocatechin-3-gallate mediates T cellular NF-kappa B inhibition and exerts neuroprotection in autoimmune encephalomyelitis

IFNβ secreted by microglia mediates clearance of myelin debris in CNS autoimmunity

Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress

Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response

Impact of HMG-CoA reductase inhibition on brain pathology

Influence of female sex and fertile age on neuromyelitis optica spectrum disorders

Interferon beta-1a sc at 25 years: a mainstay in the treatment of multiple sclerosis over the period of one generation

Interferon-β-related tumefactive brain lesion in a Caucasian patient with neuromyelitis optica and clinical stabilization with tocilizumab

Is It Too Early to Predict the Failure of Natalizumab in NMO?—Reply

Lack of tumor necrosis factor-related apoptosis-inducing ligand but presence of its receptors in the human brain

Long-term Therapy With Interleukin 6 Receptor Blockade in Highly Active Neuromyelitis Optica Spectrum Disorder

Longitudinal optic neuritis-unrelated visual evoked potential changes in NMO spectrum disorders

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin.

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients

Natalizumab restores aberrant miRNA expression profile in multiple sclerosis and reveals a critical role for miR-20b

Neurodegeneration in autoimmune demyelination: recent mechanistic insights reveal novel therapeutic targets

Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses

Neuronal damage in brain inflammation

Neuroprotective effect of combination therapy of glatiramer acetate and epigallocatechin-3-gallate in neuroinflammation

Optical coherence tomography in parkinsonian syndromes

Oral high-dose atorvastatin treatment in relapsing-remitting multiple sclerosis

Patterns of retinal damage facilitate differential diagnosis between Susac syndrome and MS.

Pneumococcal meningitis and vaccine effects in the era of conjugate vaccination: results of 20 years of nationwide surveillance in Germany

Premature aging of the hippocampal neurogenic niche in adult Bmal1-deficient mice

Progressive change in primary progressive multiple sclerosis normal-appearing white matter: a serial diffusion magnetic resonance imaging study

Regulation of self-reactive T cells by human immunoglobulins--implications for multiple sclerosis therapy

Retinal Neurodegeneration in Wilson’s Disease Revealed by Spectral Domain Optical Coherence Tomography ⬇️

Retinal inner nuclear layer volume reflects inflammatory disease activity in multiple sclerosis; a longitudinal OCT study

Retinal pathology in idiopathic moyamoya angiopathy detected by optical coherence tomography

Serum neurofilament light chain: No clear relation to cognition and neuropsychiatric symptoms in stable MS

Serum peptide reactivities may distinguish neuromyelitis optica subgroups and multiple sclerosis

Targeting B Cells to Modify MS, NMOSD, and MOGAD: Part 1

Targeting B cells to modify MS, NMOSD, and MOGAD: Part 2

The Rare IL22RA2 Signal Peptide Coding Variant rs28385692 Decreases Secretion of IL-22BP Isoform-1, -2 and -3 and Is Associated with Risk for Multiple Sclerosis

The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases

The role of TRAIL/TRAIL receptors in central nervous system pathology

Treatment of optic neuritis with erythropoietin (TONE): a randomised, double-blind, placebo-controlled trial-study protocol

Treatment of relapsing paralysis in experimental encephalomyelitis by targeting Th1 cells through atorvastatin

Update on biomarkers in neuromyelitis optica

Update on the diagnosis and treatment of neuromyelitis optica: recommendations of the Neuromyelitis Optica Study Group (NEMOS).

Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder

Very late-onset neuromyelitis optica spectrum disorder beyond the age of 75.

Visual evoked potentials in neuromyelitis optica and its spectrum disorders