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List of works by Colin J Sutherland

A molecular barcode to inform the geographical origin and transmission dynamics of Plasmodium vivax malaria

scientific article published on 13 February 2020

A simple, high-throughput, colourimetric, field applicable loop-mediated isothermal amplification (HtLAMP) assay for malaria elimination.

scientific article

A trial of the efficacy, safety and impact on drug resistance of four drug regimens for seasonal intermittent preventive treatment for malaria in Senegalese children

scientific article

Addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children causes a significant but short-lived reduction in infectiousness for mosquitoes

scientific article published on January 2004

African origin of the malaria parasite Plasmodium vivax

scientific article

Alternative pathway to reduced artemisinin susceptibility in Plasmodium falciparum

scientific article published on 28 November 2018

Alternatively spliced transcripts and novel pseudogenes of the Plasmodium falciparum resistance-associated locus pfcrt detected in East African malaria patients

scientific article

Amodiaquine resistance in Plasmodium falciparum malaria in Afghanistan is associated with the pfcrt SVMNT allele at codons 72 to 76.

scientific article

An analysis of large structural variation in global Plasmodium falciparum isolates identifies a novel duplication of the chloroquine resistance associated gene.

scientific article published on 4 June 2019

An observational study of malaria in British travellers: Plasmodium ovale wallikeri and Plasmodium ovale curtisi differ significantly in the duration of latency

scientific article (publication date: 28 May 2013)

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

scientific article (publication date: 19 July 2012)

Antibody responses to surface antigens of Plasmodium falciparum gametocyte-infected erythrocytes and their relation to gametocytaemia

scientific article published on 16 April 2016

Artemisinin resistance-associated markers in Plasmodium falciparum parasites from the China-Myanmar border: predicted structural stability of K13 propeller variants detected in a low-prevalence area

article

Artemther-lumefantrine is partially effective for treating chronic multi-species malaria in Ugandan pre-school children

article

Assessment of Markers of Antimalarial Drug Resistance in Plasmodium falciparum Isolates from Pregnant Women in Lagos, Nigeria

scientific article published in 2016

Carriage of chloroquine-resistant parasites and delay of effective treatment increase the risk of severe malaria in Gambian children

scientific article published on 22 September 2005

Changes in malaria parasite drug resistance in an endemic population over a 25-year period with resulting genomic evidence of selection

scientific article

Chloroquine-resistant Plasmodium falciparum infections among UK travellers returning with malaria after chloroquine prophylaxis

scientific article published on 2 May 2007

Chloroquine/sulphadoxine-pyrimethamine for gambian children with malaria: transmission to mosquitoes of multidrug-resistant Plasmodium falciparum

scientific article

Clinical evaluation of a loop-mediated amplification kit for diagnosis of imported malaria

scientific article published on 30 April 2013

Cluster of falciparum malaria cases in UK airport

scientific article published on August 2008

Combination therapy counteracts the enhanced transmission of drug-resistant malaria parasites to mosquitoes

scientific article published on October 2004

Combined DNA extraction and antibody elution from filter papers for the assessment of malaria transmission intensity in epidemiological studies

scientific article published on 02 August 2013

Contribution of Plasmodium knowlesi to Multispecies Human Malaria Infections in North Sumatera, Indonesia

scientific article

Culture-adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers

scientific article published on 13 September 2013

Cutaneous Leishmaniasis in Khyber Pakhtunkhwa Province of Pakistan: Clinical Diversity and Species-Level Diagnosis

scientific article published on 06 September 2016

Detecting malaria parasites outside the blood.

scientific article published in June 2009

Detection of persistent Plasmodium spp. infections in Ugandan children after artemether-lumefantrine treatment

scientific article published on 16 May 2014

Detection of single-nucleotide polymorphisms in Plasmodium falciparum by PCR primer extension and lateral flow immunoassay.

scientific article

Determination of the processes driving the acquisition of immunity to malaria using a mathematical transmission model

scientific article

Dimorphism in genes encoding sexual-stage proteins of Plasmodium ovale curtisi and Plasmodium ovale wallikeri

scientific article published on 24 March 2015

Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu loci of Plasmodium falciparum in Kenyan children treated with ACT.

scientific article

Drug-drug Interactions between Lumefantrine and Commonly-used Antiretroviral Treatment: An Individual Participant Data Population Pharmacokinetic Meta-Analysis

scientific article published on 18 February 2020

Drug-resistant genotypes and multi-clonality in Plasmodium falciparum analysed by direct genome sequencing from peripheral blood of malaria patients

scientific article published in 2011

Effectiveness of Seasonal Malaria Chemoprevention in Children under Ten Years of Age in Senegal: A Stepped-Wedge Cluster-Randomised Trial

scientific article

Epidemiology of subpatent Plasmodium falciparum infection: implications for detection of hotspots with imperfect diagnostics

scientific article published on July 2013

Extended malaria parasite clearance time in African children following artemisinin-combination therapy enhances transmission to Anopheles mosquitoes

article

Filter paper collection of Plasmodium falciparum mRNA for detecting low-density gametocytes

scientific article published on 8 August 2012

Gametocyte carriage in Plasmodium falciparum-infected travellers

scientific article

Genetic dissociation of three antigenic genes in Plasmodium ovale curtisi and Plasmodium ovale wallikeri

scientific article published on 06 June 2019

Genetic diversity of the Plasmodium falciparum GTP-cyclohydrolase 1, dihydrofolate reductase and dihydropteroate synthetase genes reveals new insights into sulfadoxine-pyrimethamine antimalarial drug resistance

scientific article published on 31 December 2020

Genetic marker suitable for identification and genotyping of Plasmodium ovale curtisi and Plasmodium ovale wallikeri

scientific article published on 25 September 2013

Genome-scale comparison of expanded gene families in Plasmodium ovale wallikeri and Plasmodium ovale curtisi with Plasmodium malariae and with other Plasmodium species

scientific article published on 5 July 2016

Genomic variation in Plasmodium vivax malaria reveals regions under selective pressure

scientific article

Global genetic diversity of var2csa in Plasmodium falciparum with implications for malaria in pregnancy and vaccine development

scientific article published in Scientific Reports

HIV-positive Nigerian adults harbour significantly higher serum lumefantrine levels than HIV negative individuals seven days after treatment for Plasmodium falciparum infection

article

Highly sensitive detection of malaria parasitemia in a malaria-endemic setting: performance of a new loop-mediated isothermal amplification kit in a remote clinic in Uganda

scientific article published on 30 April 2013

Hot spot or not: a comparison of spatial statistical methods to predict prospective malaria infections

scientific article published on 11 February 2014

Identification and deconvolution of cross-resistance signals from antimalarial compounds using multidrug-resistant Plasmodium falciparum strains

scientific article

Identifying Recrudescent Plasmodium falciparum in Treated Malaria Patients by Real-time PCR and High Resolution Melt Analysis of Genetic Diversity.

scientific article published on 4 July 2018

Impact of RTS,S/AS02(A) and RTS,S/AS01(B) on genotypes of P. falciparum in adults participating in a malaria vaccine clinical trial

scientific article

In-vitro sensitivity of Pakistani Leishmania tropica field isolate against buparvaquone in comparison to standard anti-leishmanial drugs

scientific article published on 21 April 2015

Inactivation of Plasmodium falciparum in whole blood by riboflavin plus irradiation

scientific article

Increased pfmdr1 copy number and sequence polymorphisms in Plasmodium falciparum isolates from Sudanese malaria patients treated with artemether-lumefantrine

scientific article

Increased sensitivity for detecting malaria parasites in human umbilical cord blood using scaled-up DNA preparation

scientific article published on 5 March 2012

Lack of K13 mutations in Plasmodium falciparum persisting after artemisinin combination therapy treatment of Kenyan children

scientific article

Loss of population levels of immunity to malaria as a result of exposure-reducing interventions: consequences for interpretation of disease trends

scientific article

Malaria epidemiology in central Myanmar: identification of a multi-species asymptomatic reservoir of infection

scientific article published on 05 January 2017

Malaria resistance to non-artemisinin partner drugs: how to reACT.

scientific article published on 12 April 2015

Malaria transmission after artemether-lumefantrine and dihydroartemisinin-piperaquine: a randomized trial

scientific article published on 6 March 2013

Mammalian malaria: Remembering the Alamo

scientific article published on 01 December 2020

Markers of anti-malarial drug resistance in Plasmodium falciparum isolates from Swaziland: identification of pfmdr1-86F in natural parasite isolates

scientific article

Measuring the efficacy of anti-malarial drugs in vivo: quantitative PCR measurement of parasite clearance

scientific article

Mitochondrial DNA targets increase sensitivity of malaria detection using loop-mediated isothermal amplification

scientific article

Molecular quantification of Plasmodium parasite density from the blood retained in used RDTs

scientific article published on 25 March 2019

Mosquito feeding assays to determine the infectiousness of naturally infected Plasmodium falciparum gametocyte carriers

scientific article

Mutations in the Plasmodium falciparum cytochrome b gene are associated with delayed parasite recrudescence in malaria patients treated with atovaquone-proguanil

scientific article published in 2008

Novel pfdhps haplotypes among imported cases of Plasmodium falciparum malaria in the United Kingdom

scientific article published on 11 May 2009

Paper-Origami-Based Multiplexed Malaria Diagnostics from Whole Blood

scientific article published on 24 August 2016

Persistence of chloroquine-resistant haplotypes of Plasmodium falciparum in children with uncomplicated Malaria in Lagos, Nigeria, four years after change of chloroquine as first-line antimalarial medicine

scientific article published on 28 April 2015

Persistent Parasitism: The Adaptive Biology of Malariae and Ovale Malaria

scientific article

Persistent detection of Plasmodium falciparum, P. malariae, P. ovale curtisi and P. ovale wallikeri after ACT treatment of asymptomatic Ghanaian school-children

scientific article

Persistent sub-microscopic parasitaemia after ACT treatment of African children.

scientific article published on 22 September 2014

Plasmodium faciparum carrying pfk13 polymorphisms harbour the SVMNT allele of pfcrt in north-western Indonesia

scientific article published on 11 May 2020

Plasmodium falciparum gametocyte dynamics in areas of different malaria endemicity

scientific article published on 03 December 2008

Plasmodium falciparum parasites with histidine-rich protein 2 (pfhrp2) and pfhrp3 gene deletions in two endemic regions of Kenya.

scientific article published on 7 November 2017

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine

scientific article

Prevalence of molecular markers of drug resistance in an area of seasonal malaria chemoprevention in children in Senegal

scientific article published on 23 April 2013

Promiscuous Expression of α-Tubulin II in Maturing Male and Female Plasmodium falciparum Gametocytes ⬇️

scientific article published on December 30, 2010

RTS,S/AS02A malaria vaccine does not induce parasite CSP T cell epitope selection and reduces multiplicity of infection

scientific article

Randomised controlled trial of two sequential artemisinin-based combination therapy regimens to treat uncomplicated falciparum malaria in African children: a protocol to investigate safety, efficacy and adherence.

scientific article published on 30 August 2017

Randomised trial of chloroquine/sulphadoxine-pyrimethamine in Gambian children with malaria: impact against multidrug-resistant P. falciparum

scientific article

Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research.

scientific article published on 17 June 2019

Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials

scientific article published on 9 July 2008

Residual Plasmodium falciparum parasitemia in Kenyan children after artemisinin-combination therapy is associated with increased transmission to mosquitoes and parasite recurrence

scientific article published on 14 August 2013

Seasonal intermittent preventive treatment with artesunate and sulfadoxine-pyrimethamine for prevention of malaria in Senegalese children: a randomised, placebo-controlled, double-blind trial

scientific article published on February 2006

Selection of pfdhfr/pfdhps alleles and declining artesunate/sulphadoxine-pyrimethamine efficacy against Plasmodium falciparum eight years after deployment in eastern Sudan

scientific article published on 19 July 2013

Sensitive Detection of Plasmodium vivax Using a High-Throughput, Colourimetric Loop Mediated Isothermal Amplification (HtLAMP) Platform: A Potential Novel Tool for Malaria Elimination

scientific article published on 12 February 2016

Temporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal Kenya

scientific article (publication date: December 2014)

The Mu subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinine

scientific article (publication date: May 2015)

The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation

scientific article published on 25 February 2020

The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis

scientific article published on 19 October 2020

The perils of PCR: can we accurately 'correct' antimalarial trials?

scientific article published in March 2010

Two nonrecombining sympatric forms of the human malaria parasite Plasmodium ovale occur globally

scientific article

Vaccination for vivax malaria: targeting the invaders

scientific article

Various pfcrt and pfmdr1 genotypes of Plasmodium falciparum cocirculate with P. malariae, P. ovale spp., and P. vivax in northern Angola

scientific article

World Antimalarial Resistance Network (WARN) III: molecular markers for drug resistant malaria

scientific article

estMOI: estimating multiplicity of infection using parasite deep sequencing data

scientific article

pfk13-Independent Treatment Failure in Four Imported Cases of Plasmodium falciparum Malaria Treated with Artemether-Lumefantrine in the United Kingdom

scientific article published on 30 January 2017

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