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List of works by Søren Brøgger Christensen

19alpha-Hydroxy-3-oxo-ursa-1,12-dien-28-oic acid, an antiplasmodial triterpenoid isolated from Canthium multiflorum

scientific article published in January 2009

6-O-Methylkrigeine, a new Amaryllidaceae alkaloid fromNerine huttoniaeSchönland

A Trojan horse in drug development: targeting of thapsigargins towards prostate cancer cells

scientific article published on March 2009

A new flavonol glycoside and other flavonoids from the aerial parts of Taverniera aegyptiaca

scientific article published on 17 April 2018

A new oxygenated ursane derivative from Canthium multiflorum

scientific article published in April 2008

A phenylpropanoid, a slovenolide, two sulphur-containing germacranes and Ca2+-ATPase inhibitors from Thapsia villosa

scientific article published on 25 August 2009

A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases ⬇️

scientific article published on April 1, 1998

Absolute configuration and antiprotozoal activity of minquartynoic acid

scientific article published in September 2000

Accelerating the Domestication of New Crops: Feasibility and Approaches

scientific article published on 16 February 2017

Alkaloid analysis by high-performance liquid chromatography-solid phase extraction-nuclear magnetic resonance: new strategies going beyond the standard

scientific article

Amaryllidaceae alkaloids from the Australasian tribe Calostemmateae with acetylcholinesterase inhibitory activity

scientific article published in 2011

Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells

scientific article published on 5 May 2009

Ancistrotanzanine A, the first 5,3'-coupled naphthylisoquinoline alkaloid, and two further, 5,8'-linked related compounds from the newly described species Ancistrocladus tanzaniensis.

scientific article

Ancistrotanzanine C and related 5,1'- and 7,3'-coupled naphthylisoquinoline alkaloids from Ancistrocladus tanzaniensis.

scientific article

Antileishmanial activity of licochalcone A in mice infected with Leishmania major and in hamsters infected with Leishmania donovani

scientific article published in June 1994

Are we ready for back-to-nature crop breeding?

scientific article published on 16 December 2014

Biosynthesis of tovarol and other sesquiterpenoids in Thapsia laciniata Rouy

scientific article published on 06 November 2018

Ca2+ influx in human T lymphocytes is induced independently of inositol phosphate production by mobilization of intracellular Ca2+ stores. A study with the Ca2+ endoplasmic reticulum-ATPase inhibitor thapsigargin ⬇️

scientific article published on October 1, 1990

Can phylogeny predict chemical diversity and potential medicinal activity of plants? A case study of Amaryllidaceae

scientific article

Carroll rearrangement to construct the norneolignan skeleton

scientific article published in January 2008

Chalcone inhibitors of the NorA efflux pump in Staphylococcus aureus whole cells and enriched everted membrane vesicles

scientific article

Chemo- and Regioselective Functionalization of Nortrilobolide: Application for Semisynthesis of the Natural Product 2-Acetoxytrilobolide

scientific article published on 16 June 2015

Comparison of the effects of thapsigargin and BAY K 8644 on spontaneous mechanical activity in rat portal vein and contractile responses of rat cardiac muscle

scientific article published on February 1, 1992

Cover Feature: Difluoroacetic Acid as a New Reagent for Direct C−H Difluoromethylation of Heteroaromatic Compounds (Chem. Eur. J. 72/2017)

Cover Feature: LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d ]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+ -ATPase Inhibitors (ChemMedChem 1/2018)

scholarly article by Truong-Thanh Tung et al published 8 January 2018 in ChemMedChem

Cranberry Juice and Combinations of Its Organic Acids Are Effective against Experimental Urinary Tract Infection

scientific article published on 04 April 2017

Critical Roles of Hydrophobicity and Orientation of Side Chains for Inactivation of Sarcoplasmic Reticulum Ca2+-ATPase with Thapsigargin and Thapsigargin Analogs

scientific article

Cyclic AMP- and inositol phosphate-independent inhibition of Ca2+ influx by cholera toxin in CD3-stimulated Jurkat T cells. A study with a cholera toxin-resistant cell variant and the Ca2+ endoplasmic reticulum-ATPase inhibitor thapsigargin ⬇️

scientific article published on August 1, 1991

Cytotoxic kurubasch aldehyde from Trichilia emetica

scientific article published on January 2007

Cytotoxic phenylpropanoids and an additional thapsigargin analogue isolated from Thapsia garganica.

scientific article published on 13 November 2006

Demethoxycurcumin Is A Potent Inhibitor of P-Type ATPases from Diverse Kingdoms of Life

scientific article published on 19 September 2016

Differential effects of thapsigargin analogues on apoptosis of prostate cancer cells: complex regulation by intracellular calcium.

scientific article published on 2 September 2013

Difluoroacetic Acid as a New Reagent for Direct C-H Difluoromethylation of Heteroaromatic Compounds

scientific article

Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relation to AIDS

scientific article published on 01 December 1988

Effects of thapsigargin in isolated rat thoracic aorta

scientific article published on 01 January 1988

Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase.

scientific article published on 16 June 2010

Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy

scientific article

Fusaric acid and analogues as Gram-negative bacterial quorum sensing inhibitors

scientific article

Hydrophilic carboxylic acids and iridoid glycosides in the juice of American and European cranberries (Vaccinium macrocarpon and V. oxycoccos), lingonberries (V. vitis-idaea), and blueberries (V. myrtillus).

scientific article published in November 2002

Identification of Natural Products Using HPLC-SPE Combined with CapNMR

scientific article published on 01 January 2007

Iminolactones as tools for inversion of the absolute configuration of α-amino acids and as inhibitors of cancer cell proliferation

scientific article

Iminolactones from Schizophyllum commune.

scientific article

Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones.

scientific article published in July 2001

Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+ depletion and the unfolded protein response.

scientific article published on 29 September 2017

Inositol trisphosphate and thapsigargin discriminate endoplasmic reticulum stores of calcium in rat brain

scientific article

Isolation of immunomodulatory triterpene acids from a standardized rose hip powder (Rosa canina L.).

scientific article published on February 2011

Isolation of linoleic and alpha-linolenic acids as COX-1 and -2 inhibitors in rose hip.

scientific article published in July 2008

Isolation of the MAO-inhibitor naringenin from Mentha aquatica L.

scientific article published on 19 February 2008

LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+ -ATPase Inhibitors.

scientific article

Large Scale Conversion of Trilobolide into the Payload of Mipsagargin: 8-<i>O</i>-(12-Aminododecanoyl)-8-<i>O</i>-Debutanoylthapsigargin

scientific article published on 05 December 2020

Licochalcone A, a new antimalarial agent, inhibits in vitro growth of the human malaria parasite Plasmodium falciparum and protects mice from P. yoelii infection

scientific article

Licochalcone A, a novel antiparasitic agent with potent activity against human pathogenic protozoan species of Leishmania

scientific article

Localization and in-Vivo Characterization of Thapsia garganica CYP76AE2 Indicates a Role in Thapsigargin Biosynthesis

scientific article

Metformin, an Anthropogenic Contaminant of Seidlitzia rosmarinus Collected in a Desert Region near the Gulf of Aqaba, Sinai Peninsula

scientific article published on 20 September 2017

Modifications of the alpha,beta-double bond in chalcones only marginally affect the antiprotozoal activities

scientific article published on 01 July 1998

New proazulene guaianolides from Thapsia villosa

scientific article published on 01 November 1990

Nonlinear relationship between ER Ca2+ depletion versus induction of the unfolded protein response, autophagy inhibition, and cell death

scientific article published on 17 September 2018

Novel inhibitory activity of the Staphylococcus aureus NorA efflux pump by a kaempferol rhamnoside isolated from Persea lingue Nees.

scientific article

Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E(2)P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump

scientific article published on 13 July 2011

Organic Hydroxylamine Derivatives. VII. Isoxazolin-5-ones. An Investigation of a Reaction Sequence Previously Stated to Give 3-Hydroxyisoxazoles

scientific article published on 01 January 1973

Phorbol Rearrangements

scientific article published on 14 September 2018

Prenylated acetophenones from Melicope obscura and Melicope obtusifolia ssp. obtusifolia var. arborea and their distribution in Rutaceae

scientific article published in 2007

Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis

scientific article published on 15 June 2018

Prostate-specific antigen-activated thapsigargin prodrug as targeted therapy for prostate cancer

scientific article published in July 2003

Sesquiterpenes from Thapsia nitida var. meridionalis and Thapsia nitida var. nitida

scientific article published on 01 November 2006

Structure-Activity Relationships of Analogs of Thapsigargin Modified at O-11 and O-12

scientific article published on 01 January 1995

Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1

scientific article

Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca2+/Mn2+-transport ATPase (SPCA1a).

scientific article published on 6 March 2017

Targeting thapsigargin towards tumors

scientific article

Thapsigargin affinity purification of intracellular P(2A)-type Ca(2+) ATPases

scientific article published on 4 January 2011

Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage. 1989.

scientific article published in December 1994

The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response

scientific article published on July 1985

The antileishmanial activity of novel oxygenated chalcones and their mechanism of action

scientific article published on 01 June 1999

The antileishmanial agent licochalcone A interferes with the function of parasite mitochondria

scientific article published on December 1995

The antiparasitic compound licochalcone a is a potent echinocytogenic agent that modifies the erythrocyte membrane in the concentration range where antiplasmodial activity is observed.

scientific article

The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations

scientific article published on 01 January 1987

The molluscicidal activity of coumarins from Ethulia conyzoides and of dicumarol

scientific article published in August 1992

Toxicodynamics of tumour promoters of mouse skin. III. Specific binding of the tumour promoter thapsigargin as measured by the cold-acetone filter assay

scientific article published on January 1, 1992

Two new antiprotozoal 5-methylcoumarins from Vernonia brachycalyx

scientific article published on May 1997

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