List of works - Massimiliano Pagani

A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin

scientific article published on 12 December 2019

A cytosolic Ezh1 isoform modulates a PRC2-Ezh1 epigenetic adaptive response in postmitotic cells.

scientific article

A high-resolution anatomical atlas of the transcriptome in the mouse embryo

scientific article

A novel polyclonal antibody library for expression profiling of poorly characterized, membrane and secreted human proteins.

scientific article

Analysis RNA-seq and Noncoding RNA.

scientific article published in January 2016

Biogem: an effective tool-based approach for scaling up open source software development in bioinformatics

scientific article

Circulating hepatitis B surface antigen particles carry hepatocellular microRNAs

scientific article

De novo transcriptome profiling of highly purified human lymphocytes primary cells

scientific article

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

scientific article published on 15 May 2015

Differences in serum and synovial CD4+ T cells and cytokine profiles to stratify patients with inflammatory osteoarthritis and rheumatoid arthritis

scientific article

Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naive state in CD4+ T cells by the microRNA miR-125b

scientific article

ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum

scientific article

Eomesodermin controls a unique differentiation program in human IL-10 and IFN-γ coproducing regulatory T cells

scientific article published on 29 November 2018

Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ

scientific article published on 20 April 2021

Extracellular MicroRNA Signature of Human Helper T Cell Subsets in Health and Autoimmunity

scientific article published on 11 January 2017

Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth

article published in the Proceedings of the National Academy of Sciences of the United States of America

Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes

scientific article

Hepatitis C Virus Deletion Mutants Are Found in Individuals Chronically Infected with Genotype 1 Hepatitis C Virus in Association with Age, High Viral Load and Liver Inflammatory Activity.

scientific article published on 25 September 2015

IL-10 promotes homeostatic proliferation of human CD8(+) memory T cells and, when produced by CD1c(+) DCs, shapes naive CD8(+) T-cell priming

scientific article published on 30 April 2016

IL-10-producing forkhead box protein 3-negative regulatory T cells inhibit B-cell responses and are involved in systemic lupus erythematosus.

scientific article

IL-21 is a central memory T cell-associated cytokine that inhibits the generation of pathogenic Th1/17 effector cells

scientific article published on 29 August 2014

Identification of New Hematopoietic Cell Subsets with a Polyclonal Antibody Library Specific for Neglected Proteins ⬇️

scientific article published on April 4, 2012

Identification of new autoantigens by protein array indicates a role for IL4 neutralization in autoimmune hepatitis

scientific article

Intestinal IFN-γ-producing Tr1-cells co-express CCR5 and PD-1, and down-regulate IL-10 in the inflamed gut of IBD patients.

scientific article published on 21 January 2018

Intracellular modulation, extracellular disposal and serum increase of MiR-150 mark lymphocyte activation

scientific article

Long Intergenic Non-Coding RNAs: Novel Drivers of Human Lymphocyte Differentiation

scientific article

Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity

scientific article

NS5A inhibitors impair NS5A-phosphatidylinositol 4-kinase IIIα complex formation and cause a decrease of phosphatidylinositol 4-phosphate and cholesterol levels in hepatitis C virus-associated membranes

scientific article published on 15 September 2014

Next-Generation Sequencing Analysis of Long Noncoding RNAs in CD4+ T Cell Differentiation

scientific article

Plasticity of human CD4 T cell subsets

scientific article published on 16 December 2014

Platelet-derived growth factor-α receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer

scientific article published on 06 June 2016

Preventing bacterial infections with pilus-based vaccines: the group B streptococcus paradigm

scientific article published in January 2009

Recognition of viral and self-antigens by TH1 and TH1/TH17 central memory cells in patients with multiple sclerosis reveals distinct roles in immune surveillance and relapses

scientific article published on 16 February 2017

Reduction of CD68+ macrophages and decreased IL-17 expression in intestinal mucosa of patients with inflammatory bowel disease strongly correlate with endoscopic response and mucosal healing following infliximab therapy

scientific article published in March 2013

Reference proteome of highly purified human Th1 cells reveals strong effects on metabolism and protein ubiquitination upon differentiation

scientific article published on September 2015

Repression of miR-31 by BCL6 stabilizes the helper function of human follicular helper T cells

scientific article

Reverse plasticity: TGF-β and IL-6 induce Th1-to-Th17-cell transdifferentiation in the gut.

scientific article published on October 2016

Role of microRNAs and long-non-coding RNAs in CD4(+) T-cell differentiation.

scientific article published on May 2013

SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention.

scientific article

Serum microRNAs as Biomarkers of Human Lymphocyte Activation in Health and Disease

scientific article published on 10 February 2014

Signal Strength and Metabolic Requirements Control Cytokine-Induced Th17 Differentiation of Uncommitted Human T Cells

scientific article published on 16 September 2015

Single Cell T Cell Receptor Sequencing: Techniques and Future Challenges

scientific article published on 18 July 2018

Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output

scientific article

Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity

scientific article published on 01 June 2018

The Association of HIV-1 Tat with Nuclei Is Regulated by Ca2+Ions and Cytosolic Factors

scientific article published in Journal of Biological Chemistry

The C-terminal domain of yeast Ero1p mediates membrane localization and is essential for function

scientific article

The CD4-centered universe of human T cell subsets.

scientific article

The Enigmatic Role of Viruses in Multiple Sclerosis: Molecular Mimicry or Disturbed Immune Surveillance?

scientific article

The circulating microRNome demonstrates distinct lymphocyte subset-dependent signatures.

scientific article

The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes

scientific article published on 05 March 2021

The light and the dark sides of Interleukin-10 in immune-mediated diseases and cancer.

scientific article published on 08 March 2016

The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4.

scientific article published on 26 January 2015

Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.

scientific article

Uncontrolled IL-17 Production by Intraepithelial Lymphocytes in a Case of non-IPEX Autoimmune Enteropathy

scientific article

miR-17∼92 family clusters control iNKT cell ontogenesis via modulation of TGF-β signaling

scientific article published on 05 December 2016

miRiadne: a web tool for consistent integration of miRNA nomenclature.

scientific article published on 20 April 2015

List of works by Massimiliano Pagani

A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin

A cytosolic Ezh1 isoform modulates a PRC2-Ezh1 epigenetic adaptive response in postmitotic cells.

A high-resolution anatomical atlas of the transcriptome in the mouse embryo

A novel polyclonal antibody library for expression profiling of poorly characterized, membrane and secreted human proteins.

Analysis RNA-seq and Noncoding RNA.

Biogem: an effective tool-based approach for scaling up open source software development in bioinformatics

Circulating hepatitis B surface antigen particles carry hepatocellular microRNAs

De novo transcriptome profiling of highly purified human lymphocytes primary cells

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

Differences in serum and synovial CD4+ T cells and cytokine profiles to stratify patients with inflammatory osteoarthritis and rheumatoid arthritis

Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naive state in CD4+ T cells by the microRNA miR-125b

ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum

Eomesodermin controls a unique differentiation program in human IL-10 and IFN-γ coproducing regulatory T cells

Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ

Extracellular MicroRNA Signature of Human Helper T Cell Subsets in Health and Autoimmunity

Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth

Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes

Hepatitis C Virus Deletion Mutants Are Found in Individuals Chronically Infected with Genotype 1 Hepatitis C Virus in Association with Age, High Viral Load and Liver Inflammatory Activity.

IL-10 promotes homeostatic proliferation of human CD8(+) memory T cells and, when produced by CD1c(+) DCs, shapes naive CD8(+) T-cell priming

IL-10-producing forkhead box protein 3-negative regulatory T cells inhibit B-cell responses and are involved in systemic lupus erythematosus.

IL-21 is a central memory T cell-associated cytokine that inhibits the generation of pathogenic Th1/17 effector cells

Identification of New Hematopoietic Cell Subsets with a Polyclonal Antibody Library Specific for Neglected Proteins ⬇️

Identification of new autoantigens by protein array indicates a role for IL4 neutralization in autoimmune hepatitis

Intestinal IFN-γ-producing Tr1-cells co-express CCR5 and PD-1, and down-regulate IL-10 in the inflamed gut of IBD patients.

Intracellular modulation, extracellular disposal and serum increase of MiR-150 mark lymphocyte activation

Long Intergenic Non-Coding RNAs: Novel Drivers of Human Lymphocyte Differentiation

Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity

NS5A inhibitors impair NS5A-phosphatidylinositol 4-kinase IIIα complex formation and cause a decrease of phosphatidylinositol 4-phosphate and cholesterol levels in hepatitis C virus-associated membranes

Next-Generation Sequencing Analysis of Long Noncoding RNAs in CD4+ T Cell Differentiation

Plasticity of human CD4 T cell subsets

Platelet-derived growth factor-α receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer

Preventing bacterial infections with pilus-based vaccines: the group B streptococcus paradigm

Recognition of viral and self-antigens by TH1 and TH1/TH17 central memory cells in patients with multiple sclerosis reveals distinct roles in immune surveillance and relapses

Reduction of CD68+ macrophages and decreased IL-17 expression in intestinal mucosa of patients with inflammatory bowel disease strongly correlate with endoscopic response and mucosal healing following infliximab therapy

Reference proteome of highly purified human Th1 cells reveals strong effects on metabolism and protein ubiquitination upon differentiation

Repression of miR-31 by BCL6 stabilizes the helper function of human follicular helper T cells

Reverse plasticity: TGF-β and IL-6 induce Th1-to-Th17-cell transdifferentiation in the gut.

Role of microRNAs and long-non-coding RNAs in CD4(+) T-cell differentiation.

SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention.

Serum microRNAs as Biomarkers of Human Lymphocyte Activation in Health and Disease

Signal Strength and Metabolic Requirements Control Cytokine-Induced Th17 Differentiation of Uncommitted Human T Cells

Single Cell T Cell Receptor Sequencing: Techniques and Future Challenges

Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output

Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity

The Association of HIV-1 Tat with Nuclei Is Regulated by Ca2+Ions and Cytosolic Factors

The C-terminal domain of yeast Ero1p mediates membrane localization and is essential for function

The CD4-centered universe of human T cell subsets.

The Enigmatic Role of Viruses in Multiple Sclerosis: Molecular Mimicry or Disturbed Immune Surveillance?

The circulating microRNome demonstrates distinct lymphocyte subset-dependent signatures.

The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes

The light and the dark sides of Interleukin-10 in immune-mediated diseases and cancer.

The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4.

Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.

Uncontrolled IL-17 Production by Intraepithelial Lymphocytes in a Case of non-IPEX Autoimmune Enteropathy

miR-17∼92 family clusters control iNKT cell ontogenesis via modulation of TGF-β signaling

miRiadne: a web tool for consistent integration of miRNA nomenclature.