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List of works by Christina Curtis

A Big Bang model of human colorectal tumor growth

scientific article

A population genetics perspective on the determinants of intra-tumor heterogeneity

scientific article published on 5 March 2017

A role for chromatin regulatory dynamics in breast cancer evolution

scientific article published on 01 September 2018

A screen of apoptosis and senescence regulatory genes for life span effects when over-expressed in Drosophila

scientific article

A sparse regulatory network of copy-number driven expression reveals putative breast cancer oncogenes

A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer

scientific article

AGBT meeting report.

scientific article

Abstract 5016: The human sub-ependymal zone harbors glioblastoma precursors and represents a distinct therapeutic target

Abstract SY36-01: Exploiting intra-tumor heterogeneity through agent-based models of tumor growth to infer properties of human malignancies

Author Correction: Quantification of subclonal selection in cancer from bulk sequencing data

scientific article published on 01 September 2018

Bayesian Network Inference Modeling Identifies TRIB1 as a Novel Regulator of Cell-Cycle Progression and Survival in Cancer Cells

scientific article published on 13 January 2017

Big Bang Tumor Growth and Clonal Evolution

scientific article

CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities

scientific article published on 11 March 2020

Calling sample mix-ups in cancer population studies

scientific article

Characterizing the ecological and evolutionary dynamics of cancer

scientific article published on 27 July 2020

Chromatin regulators mediate anthracycline sensitivity in breast cancer

scientific article published on 07 November 2019

Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy

scientific article published in Nature Communications

Clonal replacement of tumor-specific T cells following PD-1 blockade

scientific article published on 29 July 2019

Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone

scientific article

Drosophila melanogaster p53 has developmental stage-specific and sex-specific effects on adult life span indicative of sexual antagonistic pleiotropy

scientific article

Early mutation bursts in colorectal tumors

scientific article

Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers

scientific article

Erratum to: Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

scientific article published on 9 February 2017

Erratum to: Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes

scientific article published on 6 May 2016

Explaining differences in saturation levels for Affymetrix GeneChip arrays

scientific article published on 12 June 2007

Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

scientific article published on July 2016

Genome-driven integrated classification of breast cancer validated in over 7,500 samples

scientific article

Genomic profiling of breast cancers

scientific article

Improving breast cancer survival analysis through competition-based multidimensional modeling

scientific article

Inferring Tumor Phylogenies from Multi-region Sequencing

scientific article published on 01 July 2016

Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.

scientific article published on 14 February 2013

Looking backward in time to define the chronology of metastasis

scientific article published on 25 June 2020

Many private mutations originate from the first few divisions of a human colorectal adenoma.

scientific article

Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice.

scientific article published on 2 April 2018

Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases

scientific article published on 18 May 2020

Pathologic and molecular responses to neoadjuvant trastuzumab and/or lapatinib from a phase II randomized trial in HER2-positive breast cancer (TRIO-US B07)

scientific article published on 17 November 2020

Penalized regression elucidates aberration hotspots mediating subtype-specific transcriptional responses in breast cancer

scientific article published on 30 July 2011

Precise inference of copy number alterations in tumor samples from SNP arrays

scientific article published on 09 September 2013

Product length, dye choice, and detection chemistry in the bead-emulsion amplification of millions of single DNA molecules in parallel

scientific article published on July 2009

Publisher Correction: Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy.

scientific article published on 30 May 2019

Quantification of subclonal selection in cancer from bulk sequencing data

scientific article published on 28 May 2018

Quantitative evidence for early metastatic seeding in colorectal cancer

scientific article published on 17 June 2019

Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling

scientific article

Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization

scientific article

Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response

scientific article published on 08 April 2021

Swift: primary data analysis for the Illumina Solexa sequencing platform.

scientific article

Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer

scientific article

The Breast Cancer Oncogene EMSY Represses Transcription of Antimetastatic microRNA miR-31.

scientific article published on 10 April 2014

The breast cancer oncogene EMSY represses transcription of antimetastatic microRNA miR-31.

scientific article published on 27 February 2014

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

scientific article (publication date: 4 April 2012)

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

scientific article (publication date: 18 April 2012)

The importance of platform annotation in interpreting microarray data

article by Mark J. Dunning et al published August 2010 in Lancet Oncology Commission

The m6A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor

scientific article published on 19 August 2020

The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer

scientific article published on 26 March 2021

The pitfalls of platform comparison: DNA copy number array technologies assessed

scientific article

The shaping and functional consequences of the microRNA landscape in breast cancer

scientific article published on 5 May 2013

Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes

scientific article

ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium

scientific article