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List of works by Zoltan Szallasi

A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer

scientific article published on 14 June 2018

A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables

scientific article published on July 2011

A clonal expression biomarker associates with lung cancer mortality

scientific article published on 07 October 2019

A comprehensive survey of the mutagenic impact of common cancer cytotoxics

scientific article published on 9 May 2016

A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes

scholarly article

A nonpromoting phorbol from the samoan medicinal plant Homalanthus nutans inhibits cell killing by HIV-1

scientific article (publication date: 29 May 1992)

A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men.

scientific article

A robust prognostic gene expression signature for early stage lung adenocarcinoma

scientific article published on 19 February 2016

A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers

scientific article published on 20 August 2006

A survey of methods for classification of gene expression data using evolutionary algorithms

scientific article

Aggregation of the Fc epsilon RI in mast cells induces the synthesis of Fos-interacting protein and increases its DNA binding-activity: the dependence on protein kinase C-beta

scientific article published on January 1996

Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer

scientific article

An Analysis of Natural T Cell Responses to Predicted Tumor Neoepitopes.

scientific article published on 15 November 2017

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

scientific article

Another surprising role for exosomes? Improving next-generation sequencing-based cancer diagnostics in liquid biopsies

scientific article published on 15 February 2016

Assessing the significance of consistently mis-regulated genes in cancer associated gene expression matrices

scientific article published in March 2002

Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast cancer: a retrospective analysis of five clinical trials

scientific article

Biasogram: visualization of confounding technical bias in gene expression data

scientific article

Both the catalytic and regulatory domains of protein kinase C chimeras modulate the proliferative properties of NIH 3T3 cells

scientific article published on November 1997

Breast cancer brain metastases show increased levels of genomic aberration-based homologous recombination deficiency scores relative to their corresponding primary tumors

scientific article published on 01 September 2018

Bryostatin 1 affects P-glycoprotein phosphorylation but not function in multidrug-resistant human breast cancer cells

Bryostatin 1 protects protein kinase C-delta from down-regulation in mouse keratinocytes in parallel with its inhibition of phorbol ester-induced differentiation

scientific article published on 01 November 1994

Build your own (virtual) cell

scientific article published on 01 April 2002

CAUSEL: an epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants

scientific article published on 23 September 2015

CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid-specific cancer cell death through autophagy induction

scientific article published on 19 October 2011

Ca(2+)-dependent and Ca(2+)-independent isozymes of protein kinase C mediate exocytosis in antigen-stimulated rat basophilic RBL-2H3 cells. Reconstitution of secretory responses with Ca2+ and purified isozymes in washed permeabilized cells.

scientific article published on January 1993

Chemotherapy treatment is associated with altered PD-L1 expression in lung cancer patients.

scientific article published on 19 April 2018

Chromosomal instability confers intrinsic multidrug resistance.

scientific article

Chromosomal instability determines taxane response

scholarly article

Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

scientific article

Coexisting Alterations of MHC Class I Antigen Presentation and IFNγ Signaling Mediate Acquired Resistance of Melanoma to Post–PD-1 Immunotherapy

scientific article published on 15 August 2022

Comparison of the roles of the C1a and C1b domains of protein kinase C alpha in ligand induced translocation in NIH 3T3 cells

scientific article published on July 1999

Complete genes may pass from food to human blood.

scientific article

Computational prediction of neoantigens: do we need more data or new approaches?

scientific article published on 21 February 2018

Concordance of exon array and real-time PCR assessment of gene expression following cancer cell cytotoxic drug exposure

scientific article published on 17 December 2008

Conformationally Constrained Analogues of Diacylglycerol. 12.1Ultrapotent Protein Kinase C Ligands Based on a Chiral 4,4-Disubstituted Heptono-1,4-lactone Template

scientific article published on 01 January 1996

Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response

scientific article

Correction of technical bias in clinical microarray data improves concordance with known biological information

scientific article

Corrigendum: An Analysis of Natural T Cell Responses to Predicted Tumor Neoepitopes.

scientific article published on 14 May 2018

Corrigendum: Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

scientific article published in Nature

Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage

scientific article published on 01 August 2020

Data from Coexisting Alterations of MHC Class I Antigen Presentation and IFNγ Signaling Mediate Acquired Resistance of Melanoma to Post–PD-1 Immunotherapy

Data from Coexisting Alterations of MHC Class I Antigen Presentation and IFNγ Signaling Mediate Acquired Resistance of Melanoma to Post–PD-1 Immunotherapy

scientific article published on 4 April 2023

Deconvoluting complex tissues for expression quantitative trait locus-based analyses

scientific article published on 06 May 2013

Deletion of the sep1+ Forkhead Transcription Factor Homologue Is Not Lethal but Causes Hyphal Growth in Schizosaccharomyces pombe

scientific article published on 01 September 1999

Detecting mutant KRAS in liquid biopsies: a biomarker searching for a role

scientific article published on 6 March 2017

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

scientific article published on 11 April 2018

Development of a rapid approach to identification of tyrosine phosphorylation sites: application to PKC delta phosphorylated upon activation of the high affinity receptor for IgE in rat basophilic leukemia cells

scientific article

Differential Activation of PKC Isozymes by 14-3-3 ζ Protein

article

Differential regulation by anti-tumor-promoting 12-deoxyphorbol-13-phenylacetate reveals distinct roles of the classical and novel protein kinase C isozymes in biological responses of primary mouse keratinocytes.

scientific article published in February 1995

Differential regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH 3T3 fibroblasts

scientific article published on January 1994

Differential selectivity of ligands for the C1a and C1b phorbol ester binding domains of protein kinase Cdelta: possible correlation with tumor-promoting activity

scientific article

Discrepancy Between Low Levels of mTOR Activity and High Levels of P-S6 in Primary Central Nervous System Lymphoma May Be Explained by PAS Domain-Containing Serine/Threonine-Protein Kinase-Mediated Phosphorylation.

scientific article

Dissociation of phorbol esters leads to immediate redistribution to the cytosol of protein kinases C alpha and C delta in mouse keratinocytes.

scientific article published on November 1994

Down-regulation of the desmosomal cadherin desmocollin 3 in human breast cancer

scientific article (publication date: July 2001)

Effect of a tyrosine 155 to phenylalanine mutation of protein kinase cdelta on the proliferative and tumorigenic properties of NIH 3T3 fibroblasts

scientific article

Effects of idebenone on the intracellular water and dry mass content as well as of the intracellular monovalent ion concentrations of brain cortical cells of SHRsp rats as revealed by X-ray microanalysis

scientific article published in November 1990

Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer

scientific article

Energy-dispersive, bulk specimen X-ray microanalytical measurement of the intracellular Na+/K+ ratio in human laryngeal tumors

scientific article published on 01 January 1987

Evaluating the significance of density, localization, and PD-1/PD-L1 immunopositivity of mononuclear cells in the clinical course of lung adenocarcinoma patients with brain metastasis.

scientific article

Evaluation of microarray preprocessing algorithms based on concordance with RT-PCR in clinical samples

scientific article

Evaluation of thrombocytosis as predictive factor in colorectal cancer

scientific article published in December 2013

Fast and accurate mutation detection in whole genome sequences of multiple isogenic samples with IsoMut

scientific article

Fatal attractors: theoretical approaches to tumor differentiation

scientific article published on 01 December 2000

From project based sample collection to a biobank

scientific article published on 01 April 2011

Functional effects of overexpression of protein kinase C-alpha, -beta, -delta, -epsilon, and -eta in the mast cell line RBL-2H3.

scientific article published on September 1997

Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer

scientific article published on 31 October 2008

Gene expression patterns and cancer

article

Genetic network analysis in light of massively parallel biological data acquisition.

scientific article

Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome

scientific article published on 2 March 2015

Homologous Recombination Deficiency (HRD) Score Predicts Response to Platinum-Containing Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer.

scientific article

Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers

scientific article published on 09 November 2020

Identification of a synthetic lethal relationship between nucleotide excision repair (NER) deficiency and irofulven sensitivity in urothelial cancer

scientific article published on 18 November 2020

Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients

scientific article

In silico prediction of tumor antigens derived from functional missense mutations of the cancer gene census

scientific article published on November 2012

Increased measurement accuracy for sequence-verified microarray probes

scientific article published on 11 August 2004

Influence of mutagenic versus non-mutagenic pre-operative chemotherapy on the immune infiltration of residual breast cancer

scientific article published on 04 July 2019

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

scientific article (publication date: 8 March 2012)

Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters

scientific article published in October 2017

Is the proliferation inhibition of K562 cells by cisplatin also a membrane effect?

scientific article published on January 1990

Jetset: selecting the optimal microarray probe set to represent a gene

scientific article

LAPTM4B gene copy number gain is associated with inferior response to anthracycline-based chemotherapy in hormone receptor negative breast carcinomas

scientific article published on 16 May 2018

Lactate dehydrogenase as a selection criterion for ipilimumab treatment in metastatic melanoma.

scientific article published on 8 March 2014

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes.

scientific article published on 29 August 2016

Long-term treatment with the PARP inhibitor niraparib does not increase the mutation load in cell line models and tumour xenografts

scientific article published on 14 November 2018

Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions.

scientific article published on 25 July 2016

Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions.

scientific article published on 26 June 2017

MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy

scientific article published on 6 November 2015

Migrating the SNP array-based homologous recombination deficiency measures to next generation sequencing data of breast cancer.

scientific article

Minimising immunohistochemical false negative ER classification using a complementary 23 gene expression signature of ER status

scientific article

Modeling the normal and neoplastic cell cycle with "realistic Boolean genetic networks": their application for understanding carcinogenesis and assessing therapeutic strategies.

scientific article published in January 1998

MuPeXI: prediction of neo-epitopes from tumor sequencing data.

scientific article

Neoantigen-directed immune escape in lung cancer evolution

scientific article published on 20 March 2019

New insights into the impact of primary lung adenocarcinoma location on metastatic sites and sequence: A multicenter cohort study

scientific article published on 05 November 2018

Non-equivalent roles for the first and second zinc fingers of protein kinase Cdelta. Effect of their mutation on phorbol ester-induced translocation in NIH 3T3 cells

scientific article

Non-promoting 12-deoxyphorbol 13-esters as potent inhibitors of phorbol 12-myristate 13-acetate-induced acute and chronic biological responses in CD-1 mouse skin

scientific article published in November 1992

Nonpromoting 12-deoxyphorbol 13-esters inhibit phorbol 12-myristate 13-acetate induced tumor promotion in CD-1 mouse skin

scientific article

Opposite prognostic roles of HIF1α and HIF2α expressions in bone metastatic clear cell renal cell cancer

scientific article published on 27 May 2016

Optimization of the BLASTN substitution matrix for prediction of non-specific DNA microarray hybridization

scientific article

Origin and Distribution of Connective Tissue and Pericytes Impacting Vascularization in Brain Metastases With Different Growth Patterns

scientific article published on 01 April 2019

Overexpression of BLM promotes DNA damage and increased sensitivity to platinum salts in triple negative breast and serous ovarian cancers

scientific article published on 14 February 2018

Overexpression of protein kinase C isoform epsilon but not delta in human interleukin-3-dependent cells suppresses apoptosis and induces bcl-2 expression

scientific article

Overexpression of protein kinase C-delta increases tight junction permeability in LLC-PK1 epithelia.

scientific article

PD-L1 Expression of Lung Cancer Cells, Unlike Infiltrating Immune Cells, Is Stable and Unaffected by Therapy During Brain Metastasis

scientific article published on 15 May 2019

Pan-cancer analysis of genomic scar signatures associated with homologous recombination deficiency suggests novel indications for existing cancer drugs

scientific article

Paradoxical relationship between chromosomal instability and survival outcome in cancer

scientific article

Parallel Evolution under Chemotherapy Pressure in 29 Breast Cancer Cell Lines Results in Dissimilar Mechanisms of Resistance ⬇️

scientific article published on February 2, 2012

Parallel evolution of tumour subclones mimics diversity between tumours

scientific article published in August 2013

Paraneoplastic thrombocytosis in gastrointestinal cancer.

scientific article published on 2 May 2016

Paraneoplastic thrombocytosis is associated with increased mortality and increased rate of lymph node metastasis in oesophageal adenocarcinoma

scientific article published on 28 June 2017

Perspective: bidirectional exosomal transport between cancer stem cells and their fibroblast-rich microenvironment during metastasis formation

scientific article published on 16 July 2018

Pervasive chromosomal instability and karyotype order in tumour evolution

scientific article published on 02 September 2020

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

scientific article

Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets

scientific article

Prognostic and predictive markers in metastatic renal cell carcinoma

scientific article published on 7 January 2013

Prostratin, a nonpromoting phorbol ester, inhibits induction by phorbol 12-myristate 13-acetate of ornithine decarboxylase, edema, and hyperplasia in CD-1 mouse skin

scientific article published on 01 October 1991

Protein kinase C epsilon subcellular localization domains and proteolytic degradation sites. A model for protein kinase C conformational changes

scientific article

Protein kinase C in cell signaling: strategies for the development of selective inhibitors

scientific article published on January 1995

Protein kinase C in signal transduction and carcinogenesis.

scientific article published on January 1994

Protein kinase C-alpha activity modulates transepithelial permeability and cell junctions in the LLC-PK1 epithelial cell line

scientific article (publication date: 6 June 1997)

Protein kinases C-beta and C-epsilon link the mast cell high-affinity receptor for IgE to the expression of c-fos and c-jun

scientific article published on August 1994

Publisher Correction: A clonal expression biomarker associates with lung cancer mortality

scientific article published on 03 June 2020

Quantification of within-sample genetic heterogeneity from SNP-array data.

scientific article

RecurrenceOnline: an online analysis tool to determine breast cancer recurrence and hormone receptor status using microarray data

scientific article

Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in cancer-associated gene expression measurements

scientific article

Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer

scientific article

Relationship of postoperative thrombocytosis and survival of patients with colorectal cancer

scientific article published on 3 April 2015

Reliability and reproducibility issues in DNA microarray measurements

scientific article

Renal Impairment Hampers Bisphosphonate Treatment in a Quarter of Lung Cancer Patients with Bone Metastasis

scientific article published on 24 August 2017

Renal Impairment Hampers Bisphosphonate Treatment in a Quarter of Lung Cancer Patients with Bone Metastasis.

scientific article

Replacing cRNA targets with cDNA reduces microarray cross-hybridization

Requirement for a Negative Charge at Threonine 60 of the FcRγ for Complete Activation of Syk

scientific article published in Journal of Biological Chemistry

Robustness of cellular functions

scientific article

SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

scientific article

Scrapie-ing’ together a signal from prions

scientific article published on 01 September 2001

Sequence-matched probes produce increased cross-platform consistency and more reproducible biological results in microarray-based gene expression measurements

scientific article

Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data.

scientific article

Significance of Primary Tumor Location and Histology for Brain Metastasis Development and Peritumoral Brain Edema in Lung Cancer

scientific article

Simplified, low-cost gene expression profiling for the prediction of outcome in breast cancer based on routine histologic specimens

scientific article published in April 2013

Simultaneous suppression of epidermal growth factor receptor and c-erbB-2 reverses aneuploidy and malignant phenotype of a human ovarian carcinoma cell line.

scientific article published on February 2004

Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer.

scientific article published on 4 June 2015

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

scientific article

Specific protein kinase C isozymes mediate the induction of keratinocyte differentiation markers by calcium.

scientific article published in February 1995

Strand Orientation Bias Detector (SOBDetector) to remove artifacts from sequencing data of formalin fixed samples

article

Supplementary Figure from Coexisting Alterations of MHC Class I Antigen Presentation and IFNγ Signaling Mediate Acquired Resistance of Melanoma to Post–PD-1 Immunotherapy

Supplementary Figure from Coexisting Alterations of MHC Class I Antigen Presentation and IFNγ Signaling Mediate Acquired Resistance of Melanoma to Post–PD-1 Immunotherapy

scientific article published on 4 April 2023

Systematic evaluation of the prognostic impact and intratumour heterogeneity of clear cell renal cell carcinoma biomarkers

scientific article published on 19 July 2014

Targeting chromosomal instability and tumour heterogeneity in HER2-positive breast cancer

scientific article

Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA-damaging agents

scientific article published on 22 March 2012

The CIN4 chromosomal instability qPCR classifier defines tumor aneuploidy and stratifies outcome in grade 2 breast cancer.

scientific article

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

scientific article

The association between germline BRCA2 variants and sensitivity to platinum-based chemotherapy among men with metastatic prostate cancer.

scientific article published on 13 June 2017

The bryostatins inhibit growth of B16/F10 melanoma cells in vitro through a protein kinase C-independent mechanism: dissociation of activities using 26-epi-bryostatin 1.

scientific article

The catalytic domain of protein kinase C chimeras modulates the affinity and targeting of phorbol ester-induced translocation

scientific article published on August 1997

The comparison of thrombocytosis and platelet-lymphocyte ratio as potential prognostic markers in colorectal cancer.

scientific article

The effect of idebenone on the passive K+ and Rb+ permeability of the brain cell membranes of CFY rats as revealed by the Rb+-discrimination ratio

scientific article published in November 1990

The effect of idebenone on the total content and solubility characteristics of proteins and osmometric behavior of the intracellular mass in brain of CFY and SHRsp rats

scientific article published in November 1990

The genome of the chicken DT40 bursal lymphoma cell line.

scientific article

The genomic imprint of cancer therapies helps timing the formation of metastases

scientific article published on 18 February 2019

The grand design

scientific article published on 01 April 2001

Thrombocytosis of Liver Metastasis from Colorectal Cancer as Predictive Factor

scientific article

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal

scientific article published on 4 April 2018

To kill two birds with one stone: a general concept in gene regulation?

article

Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution.

scientific article

Tracking the Evolution of Non-Small-Cell Lung Cancer

scientific article published on 26 April 2017

Trading “wet-work” for network

scientific article published on 01 April 2002

Tumor mutation burden forecasts outcome in ovarian cancer with BRCA1 or BRCA2 mutations

scientific article

Tumor necrosis correlates with PD-L1 and PD-1 expression in lung adenocarcinoma

scientific article published on 19 April 2019

TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen

scientific article (publication date: October 2015)

Tyrosine phosphorylation of protein kinase C-delta in response to the activation of the high-affinity receptor for immunoglobulin E modifies its substrate recognition

scientific article

Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-delta

scientific journal article

Universal scaling laws in metro area election results.

scientific article published on 22 February 2018

With a little help from our (four-legged) friends

scientific article published on 01 October 2000

[Possibilities of immune checkpoint inhibitor therapy for patients with metastatic non-small cell lung cancer]

scientific article published on 26 July 2019

release of MVB-like small extracellular vesicle clusters by colorectal carcinoma cells

scientific article published on 08 April 2019

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