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List of works by Marco Gerlinger

Acquired resistance to crizotinib from a mutation in CD74-ROS1.

scientific article published in September 2013

Anti-cancer drug resistance: understanding the mechanisms through the use of integrative genomics and functional RNA interference.

scientific article published on 21 April 2010

Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast cancer: a retrospective analysis of five clinical trials

scientific article

Author Correction: Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer

scientific article published on 29 January 2020

CEA expression heterogeneity and plasticity confer resistance to the CEA-targeting bispecific immunotherapy antibody cibisatamab (CEA-TCB) in patient-derived colorectal cancer organoids

article

Cancer (r)evolution

scientific article published on 01 August 2017

Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine

scientific article

Cancer: evolution within a lifetime

scientific article published on October 2014

Circulating Tumour DNA Sequencing Identifies a Genetic Resistance-Gap in Colorectal Cancers with Acquired Resistance to EGFR-Antibodies and Chemotherapy

scientific article published on 11 December 2020

Circulating tumour DNA, a promising biomarker for the management of colorectal cancer

scientific article published on 16 December 2017

Classifying the evolutionary and ecological features of neoplasms

scientific article published on 15 September 2017

Computational optimisation of targeted DNA sequencing for cancer detection.

scientific article published on 3 December 2013

Dissecting cancer evolution at the macro-heterogeneity and micro-heterogeneity scale.

scientific article published on 31 December 2014

Efficacy and Cardiotoxic Safety Profile of Raltitrexed in Fluoropyrimidines-Pretreated or High-Risk Cardiac Patients With GI Malignancies: Large Single-Center Experience

scientific article published on 29 September 2018

Egr-1 induces the expression of its corepressor nab2 by activation of the nab2 promoter thereby establishing a negative feedback loop

scientific article

Elevated LDH predicts poor outcome of recurrent germ cell tumours treated with dose dense chemotherapy

scientific article published on 13 August 2010

Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer

scientific article published on 16 January 2020

Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target

scientific article

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

scientific article

Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome

scientific article published on 2 March 2015

Heterogeneous response and progression patterns reveal phenotypic heterogeneity of tyrosine kinase inhibitor response in metastatic renal cell carcinoma

scientific article

How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine ⬇️

scientific article published on September 28, 2010

Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment

scientific article published on 18 November 2019

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

scientific article (publication date: 8 March 2012)

Intratumor heterogeneity: seeing the wood for the trees

scientific article

Intratumour heterogeneity in urologic cancers: from molecular evidence to clinical implications

scientific article published on 02 May 2014

Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters

scientific article published in October 2017

Investigating the feasibility of tumour molecular profiling in gastrointestinal malignancies in routine clinical practice

scientific article published in January 2018

Metastasis seeding cells: Lone invaders or mass migrators?

scientific article published on 31 January 2018

Parallel evolution of tumour subclones mimics diversity between tumours

scientific article published in August 2013

Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets

scientific article

Prognostic and predictive markers in metastatic renal cell carcinoma

scientific article published on 7 January 2013

SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

scientific article

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

scientific article

Spontaneous CD8 T cell responses against the melanocyte differentiation antigen RAB38/NY-MEL-1 in melanoma patients

scientific article published on December 2006

Surveillance investigations after high-dose therapy with stem cell rescue for recurrent follicular lymphoma have no impact on management

scientific article

Systematic evaluation of the prognostic impact and intratumour heterogeneity of clear cell renal cell carcinoma biomarkers

scientific article published on 19 July 2014

The effect of VEGF-targeted therapy on biomarker expression in sequential tissue from patients with metastatic clear cell renal cancer.

scientific article

The promise of circulating tumor cell analysis in cancer management

scientific article

Translating Seminoma Genomic Landscapes into Clinical Practice

scientific article published on 02 February 2015

Treatment and Survival Outcome of BRAF-Mutated Metastatic Colorectal Cancer: A Retrospective Matched Case-Control Study

scientific article published on 16 October 2017

Ultra-Sensitive Mutation Detection and Genome-Wide DNA Copy Number Reconstruction by Error-Corrected Circulating Tumor DNA Sequencing

scientific article published in November 2018

Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas

scientific article

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