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List of works by Myles Brown

26th Pezcoller Symposium: Cancers Driven by Hormones

8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.

scientific article

A Bayesian model for single cell transcript expression analysis on MERFISH data

scientific article published on 01 July 2019

A Bayesian model for single cell transcript expression analysis on MERFISH data

scientific article published on 01 March 2019

A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer

scientific article

A closer look into DNase I hypersensitivity

scientific article published on 18 March 2013

A comprehensive view of nuclear receptor cancer cistromes

scientific article published on 22 September 2011

A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth

scientific article published on August 2007

A less invasive method for orthotopic injection of breast cancer cells into the mouse mammary gland

scientific article published on 9 July 2016

A major chromatin regulator determines resistance of tumor cells to T cell-mediated killing

scientific article published on 4 January 2018

AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor

scientific article

AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer.

scientific article published on 06 October 2008

ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer

scientific article published on 14 February 2019

Abstract PR06: CRISPR screens identified drivers of endocrine resistance and synthetic lethal vulnerabilities in breast cancer

Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer

scientific article published on 11 May 2020

Adult body size and physical activity in relation to risk of breast cancer according to tumor androgen receptor status

scientific article

Advances in estrogen receptor biology: prospects for improvements in targeted breast cancer therapy

scientific article

Agonist and chemopreventative ligands induce differential transcriptional cofactor recruitment by aryl hydrocarbon receptor

scientific article

Alcohol Consumption and Risk of Breast Cancer by Tumor Receptor Expression

scientific article

Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations

scientific article published in February 2018

Amplified in Breast Cancer-1 Glutamine Repeat and Prostate Cancer Risk

Amplitude modulation of androgen signaling by c-MYC.

scientific article published on 25 March 2013

An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence

scientific article published on 05 January 2021

An Integrative Pharmacogenomic Approach Identifies Two-drug Combination Therapies for Personalized Cancer Medicine

scientific article published on 26 February 2016

Androgen Receptor Expression and Breast Cancer Survival: Results From the Nurses' Health Studies

scientific article published on 15 November 2018

Androgen Receptor Is a Non-canonical Inhibitor of Wild-Type and Mutant Estrogen Receptors in Hormone Receptor-Positive Breast Cancers

scientific article published on 23 October 2019

Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer

scientific article

Androgen receptor CAG repeat polymorphism and risk of TMPRSS2:ERG-positive prostate cancer

scientific article

Androgen receptor expression in normal breast tissue and subsequent breast cancer risk

scientific article published on 21 September 2018

Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1.

scientific article published on October 2011

Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes

scientific article

Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

scientific article published on July 2009

BAG1L: a promising therapeutic target for androgen receptor-dependent prostate cancer

scientific article published on 01 May 2019

BINOCh: binding inference from nucleosome occupancy changes.

scientific article

BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation

scientific article

Blockade of AP-1 Potentiates Endocrine Therapy and Overcomes Resistance.

scientific article published on 10 March 2016

CARM1 regulates estrogen-stimulated breast cancer growth through up-regulation of E2F1.

scientific article published in January 2008

CD151 accelerates breast cancer by regulating alpha 6 integrin function, signaling, and molecular organization

scientific article published on May 2008

CRISPR Screens Identify Essential Cell Growth Mediators in BRAF Inhibitor-resistant Melanoma

scientific article published on 12 May 2020

CaM kinase kinase beta-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells

scientific article published on 22 November 2010

Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT.

scientific article

Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers

scientific article

ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline

scientific article

Chromatin immunoprecipitation from fixed clinical tissues reveals tumor-specific enhancer profiles

scientific article published on 25 April 2016

Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1

scientific article

Cistrome Cancer: A Web Resource for Integrative Gene Regulation Modeling in Cancer

scientific article published in November 2017

Cistrome Data Browser: a data portal for ChIP-Seq and chromatin accessibility data in human and mouse

scientific article

Cistrome Data Browser: expanded datasets and new tools for gene regulatory analysis

scientific article published on 01 January 2019

Cistrome: an integrative platform for transcriptional regulation studies

scientific article

CistromeFinder for ChIP-seq and DNase-seq data reuse

scientific article

Cistromics of hormone-dependent cancer

scientific article (publication date: June 2009)

Clonal tracing reveals diverse patterns of response to immune checkpoint blockade

scientific article published on 15 October 2020

Coactivator AIB1 links estrogen receptor transcriptional activity and stability

scholarly article

Coactivator function defines the active estrogen receptor alpha cistrome

scientific article published on 13 April 2009

Combining chromatin immunoprecipitation and oligonucleotide tiling arrays (ChIP-Chip) for functional genomic studies

scientific article published in January 2009

Consideration of breast cancer subtype in targeting the androgen receptor

scientific article published on 08 May 2019

Control of androgen receptor action by a novel nuclear receptor binding motif in Bag-1L.

scientific article published on 18 March 2013

Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase

scientific article

Control of steroid receptor dynamics and function by genomic actions of the cochaperones p23 and Bag-1L

scientific article

Coregulator control of androgen receptor action by a novel nuclear receptor-binding motif

scientific article published on 12 February 2014

Coregulator expression and breast cancer: improving the predictive power of estrogen receptor alpha.

scientific article

Correction: Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells

scientific article published on 01 July 2020

D538G mutation in estrogen receptor-α: A novel mechanism for acquired endocrine resistance in breast cancer

scientific article published on 11 November 2013

Deciphering essential cistromes using genome-wide CRISPR screens

scientific article published on 14 November 2019

Definition of a FoxA1 Cistrome that is crucial for G1 to S-phase cell-cycle transit in castration-resistant prostate cancer

scientific article

Determinants of transcription factor regulatory range

scientific article published on 18 May 2020

Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer

scientific article published on 10 August 2017

Differential DNase I hypersensitivity reveals factor-dependent chromatin dynamics

scientific article

Differential impact of RB status on E2F1 reprogramming in human cancer

scientific article

Differentiation-Specific Histone Modifications Reveal Dynamic Chromatin Interactions and Partners for the Intestinal Transcription Factor CDX2

Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2

scientific article

Digital quantification of gene expression in sequential breast cancer biopsies reveals activation of an immune response

scientific article

ERAP140, a conserved tissue-specific nuclear receptor coactivator

scientific article

ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer

scientific article published on 15 February 2013

ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor.

scientific article published on 16 May 2016

ERG-mediated coregulator complex formation maintains androgen receptor signaling in prostate cancer

scientific article published on 15 September 2020

ESR1 mutations—a mechanism for acquired endocrine resistance in breast cancer

scientific article published on 30 June 2015

EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent

scientific article

Elucidation of the ELK1 target gene network reveals a role in the coordinate regulation of core components of the gene regulation machinery

scientific article

Embryonic transcription factor SOX9 drives breast cancer endocrine resistance

scientific article published on 15 May 2017

Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor-positive breast cancer

scientific article published on 07 January 2014

Emerging data on the efficacy and safety of fulvestrant, a unique antiestrogen therapy for advanced breast cancer

scientific article

Enhanced efficacy of simultaneous PD-1 and PD-L1 immune checkpoint blockade in high grade serous ovarian cancer

scientific article published on 06 November 2020

Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation

scientific article

Enhancer-Mediated Oncogenic Function of the Menin Tumor Suppressor in Breast Cancer.

scientific article

Enhancing Therapy: It's about Time

scientific article published on 01 August 2018

Epigenetic remodeling regulates transcriptional changes between ovarian cancer and benign precursors

scientific article published on August 2016

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers

scientific article

Erratum: Regulation of ERBB2 by oestrogen receptor–PAX2 determines response to tamoxifen

scientific article published in Nature

Estradiol-regulated microRNAs control estradiol response in breast cancer cells

scientific article published on 14 June 2009

Estrogen Induces c-myc Gene Expression via an Upstream Enhancer Activated by the Estrogen Receptor and the AP-1 Transcription Factor ⬇️

scientific article published on August 11, 2011

Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival

scientific article

Estrogen receptor prevents p53-dependent apoptosis in breast cancer

scientific article

Estrogen receptor signaling is reprogrammed during breast tumorigenesis

scientific article published on 20 May 2019

Estrogen receptor target gene: an evolving concept

scientific article

Estrogen-dependent and estrogen-independent mechanisms contribute to AIB1-mediated tumor formation

scientific article

Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer

scientific article

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy

scientific article published on 09 July 2018

Evidence that the CAG repeat in the androgen receptor gene is associated with the age-related decline in serum androgen levels in men

article

FOXA1 is a potential oncogene in anaplastic thyroid carcinoma

scientific article

FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer

scientific article published on 06 October 2016

FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer

scientific article published on 11 December 2019

FiTAc-seq: fixed-tissue ChIP-seq for H3K27ac profiling and super-enhancer analysis of FFPE tissues

scientific article published on 26 June 2020

Formation of the Androgen Receptor Transcription Complex

Formation of the androgen receptor transcription complex

scientific article published on March 2002

FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription

scientific article

Gene expression profiling of prostate tissue identifies chromatin regulation as a potential link between obesity and lethal prostate cancer

scientific article published on 12 July 2017

Genome-Scale Signatures of Gene Interaction from Compound Screens Predict Clinical Efficacy of Targeted Cancer Therapies

scientific article published on 6 February 2018

Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library

scientific article

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

scientific article published on 13 June 2017

Genome-wide analysis of estrogen receptor binding sites

scientific article (publication date: November 2006)

Genome-wide impact of androgen receptor trapped clone-27 loss on androgen-regulated transcription in prostate cancer cells

scientific article

Genomic collaboration of estrogen receptor alpha and extracellular signal-regulated kinase 2 in regulating gene and proliferation programs

scientific article

GlcNAcylation of histone H2B facilitates its monoubiquitination

scientific article

Growth factor requirements and basal phenotype of an immortalized mammary epithelial cell line ⬇️

scientific article published on January 1, 2002

Growth factor stimulation induces a distinct ER(alpha) cistrome underlying breast cancer endocrine resistance

scientific article

Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells

scientific article published on 01 July 2020

High Expression of FGD3, a Putative Regulator of Cell Morphology and Motility, Is Prognostic of Favorable Outcome in Multiple Cancers

scientific article published on 13 October 2017

High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene

article

High-dimensional genomic data bias correction and data integration using MANCIE

scientific article

High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program

scientific article published on 25 September 2019

How drug resistance takes shape

scientific article

Human estrogen receptor (ER) gene promoter-P1: estradiol-independent activity and estradiol inducibility in ER+ and ER- cells

scientific article

Impact of a Pre-Operative Exercise Intervention on Breast Cancer Proliferation and Gene Expression: Results from the Pre-Operative Health and Body (PreHAB) Study

scientific article published on 24 April 2019

Importance of Breast Cancer Subtype in the Development of Androgen Receptor Directed Therapy

scientific article

Improved design and analysis of CRISPR knockout screens

scientific article published on 01 December 2018

Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition

scientific article published on 17 June 2020

Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro

scientific article published on 21 May 2009

Inhibition of MAN2A1 enhances tumor response to anti-PD-L1

scientific article published on 28 July 2020

Integrative Analysis Reveals the Transcriptional Collaboration between EZH2 and E2F1 in the Regulation of Cancer-Related Gene Expression

scientific article published on 9 December 2015

Integrative analyses of single-cell transcriptome and regulome using MAESTRO

scientific article published on 07 August 2020

Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer

scientific article published on 15 March 2016

Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis

scholarly article

Integrative analysis of pooled CRISPR genetic screens using MAGeCKFlute

scientific article published on 01 February 2019

Integrative eQTL-based analyses reveal the biology of breast cancer risk loci

scientific article

Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer

scientific article published on 02 June 2013

Integrin αvβ6-TGFβ-SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer

scientific article published on 22 December 2020

Interplay between estrogen receptor and AKT in estradiol-induced alternative splicing

scientific article

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.

scientific article

LLGL2 rescues nutrient stress by promoting leucine uptake in ER+ breast cancer

scientific article published on 17 April 2019

Lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells

article

Lisa: inferring transcriptional regulators through integrative modeling of public chromatin accessibility and ChIP-seq data

scientific article published on 07 February 2020

Loss of estrogen-regulated microRNA expression increases HER2 signaling and is prognostic of poor outcome in luminal breast cancer

scientific article

Lysine-specific demethylase 1 has dual functions as a major regulator of androgen receptor transcriptional activity.

scientific article

MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens

scientific article

MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets

scientific article published on 13 May 2022

MYC regulation of a "poor-prognosis" metastatic cancer cell state

scientific article

Mapping the Androgen Receptor Cistrome

Measuring residual estrogen receptor availability during fulvestrant therapy in patients with metastatic breast cancer

scientific article published on 7 November 2014

Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis

scientific article

MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A.

scientific article published on 17 June 2013

Model-based analysis of ChIP-Seq (MACS)

scientific article

Model-based analysis of tiling-arrays for ChIP-chip.

scientific article

Modeling cis-regulation with a compendium of genome-wide histone H3K27ac profiles.

scientific article published on 27 July 2016

Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat

scientific article

Modulator recognition factor 1, an AT-rich interaction domain family member, is a novel corepressor for estrogen receptor alpha

scientific article published on 7 June 2005

Molecular cloning of cDNA for human von Willebrand factor: authentication by a new method

scientific article

Molecular determinants for the tissue specificity of SERMs

scientific article (publication date: 29 March 2002)

Multimodal regulation of E2F1 gene expression by progestins

scientific article

NF-κB activation-induced anti-apoptosis renders HER2-positive cells drug resistant and accelerates tumor growth

scientific article

Nkx3-1 and LEF-1 function as transcriptional inhibitors of estrogen receptor activity

scientific article

No association between a single nucleotide polymorphism in CYP19 and breast cancer risk

scientific article published on 01 February 2002

Nucleosome dynamics define transcriptional enhancers

scientific article

Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer.

scientific article published on 16 June 2016

Overview consensus statement. Newer approaches to androgen deprivation therapy in prostate cancer

scientific article

PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair.

scientific article

PAX8 and lineage dependence in high grade serous ovarian cancer

scholarly article by Kevin M. Elias et al published December 2015 in Gynecologic Oncology

PDEF promotes luminal differentiation and acts as a survival factor for ER-positive breast cancer cells

scientific article published on June 2013

PET imaging of oestrogen receptors in patients with breast cancer

scientific article published on October 2013

PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer

scientific article published on 7 June 2016

PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B

scientific article

PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy

scientific article published on 25 March 2015

Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function

scientific article published in January 2018

Pleiotropic mechanisms drive endocrine resistance in the three-dimensional bone microenvironment

scientific article published on 28 August 2020

Polycomb-independent activity of EZH2 in castration resistant prostate cancer

Polymorphic repeat in AIB1 does not alter breast cancer risk

scientific article

Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer

scientific article

Pre-diagnostic sex hormone levels and survival among breast cancer patients

scientific article published on 02 January 2019

Premenopausal plasma osteoprotegerin and breast cancer risk: a case-control analysis nested within the Nurses' Health Study II

scientific article published on 10 April 2020

Primate-specific evolution of an LDLR enhancer

scientific article published on 2 August 2006

Proceedings of the Fifth International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer: conference summary statement

scientific article published in February 2006

Proceedings of the Third International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: Conference Summary Statement

scientific article published on 01 January 2004

Progesterone receptor isoforms, agonists and antagonists differentially reprogram estrogen signaling.

scientific article published on 28 September 2017

Prognostic and predictive value of androgen receptor expression in postmenopausal women with estrogen receptor-positive breast cancer: results from the Breast International Group Trial 1-98

Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells

scientific article

Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR.

scientific article

Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance

scientific article published on January 2017

Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification

scientific article

Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen

scientific article

Research resource: Aorta- and liver-specific ERα-binding patterns and gene regulation by estrogen

scientific article

Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

scientific article published on 6 January 2016

Role of diet in prostate cancer: the epigenetic link

scientific article published on 22 December 2014

Role of steroid receptor and coregulator mutations in hormone-dependent cancers

scientific article published on 03 April 2017

SLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer

scientific article

SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen

scientific article published on January 1987

Segregation of steroid receptor coactivator-1 from steroid receptors in mammary epithelium

scientific article published on January 1999

Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein

scientific article

Sequence determinants of improved CRISPR sgRNA design

scientific article published on 10 June 2015

Spatial and temporal recruitment of androgen receptor and its coactivators involves chromosomal looping and polymerase tracking

scientific article published on September 2005

Specific association of estrogen receptor beta with the cell cycle spindle assembly checkpoint protein, MAD2

scientific article

Subcellular localization of activated AKT in estrogen receptor- and progesterone receptor-expressing breast cancers: potential clinical implications

scientific article

Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer

scientific article published on 01 October 2021

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer

scientific article published on 07 May 2020

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets

scientific article published on 7 February 2008

TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions

scientific article

TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response

scientific article published on 01 January 2022

TMPRSS2:ERG blocks neuroendocrine and luminal cell differentiation to maintain prostate cancer proliferation

scientific article published on 29 September 2014

TOP2A and EZH2 Provide Early Detection of an Aggressive Prostate Cancer Subgroup

scientific article

TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer

scientific article published on 24 May 2016

TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer

scientific article published on 01 October 2018

Tamoxifen resistance in breast cancer is regulated by the EZH2-ERα-GREB1 transcriptional axis.

scientific article

Target gene-specific regulation of androgen receptor activity by p42/p44 mitogen-activated protein kinase

scientific article published on 11 September 2008

Target-directed enediynes: designed estramycins

scientific article published in June 2001

Targeting NF-kappaB in Waldenstrom macroglobulinemia

scientific article

Targeting androgen receptor in estrogen receptor-negative breast cancer

scientific article

Targeting the AIB1 oncogene through mammalian target of rapamycin inhibition in the mammary gland

scientific article published in December 2006

Targeting the androgen receptor in breast cancer

scientific article published on February 2015

Targeting transcriptional co-activators in advanced prostate cancer

scientific article published on 9 September 2016

Tetradian oscillation of estrogen receptor α is necessary to prevent liver lipid deposition.

scientific article

The CAG repeat within the androgen receptor gene and its relationship to prostate cancer

scientific article

The Evolving Role of the Estrogen Receptor Mutations in Endocrine Therapy-Resistant Breast Cancer

scientific article

The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer

scientific article published on 01 October 2019

The OXR domain defines a conserved family of eukaryotic oxidation resistance proteins

scientific article

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

scientific article published on April 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

scientific article published on 11 July 2016

The RasGAP gene, RASAL2, is a tumor and metastasis suppressor

scientific article published on September 2013

The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.

scientific article published on 29 November 2018

The Sly Oncogene: FOXA1 Mutations in Prostate Cancer

scientific article published on 01 August 2019

The altered expression of MiR-221/-222 and MiR-23b/-27b is associated with the development of human castration resistant prostate cancer

scientific article

The androgen receptor CAG repeat polymorphism and risk of breast cancer in the Nurses' Health Study

scientific article published on 01 February 2002

The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis

scientific article

The dysregulated pharmacology of clinically relevant ESR1 mutants is normalized by ligand-activated WT receptor

scientific article published on 07 May 2020

The joint effect of smoking and AIB1 on breast cancer risk in BRCA1 mutation carriers

scientific article published on 22 October 2005

The role of TRIM24 during prostate cancer progression.

scientific article

The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines

scientific article

TransCONFIRM: Identification of a Genetic Signature of Response to Fulvestrant in Advanced Hormone Receptor-Positive Breast Cancer.

scientific article published on 16 May 2016

Transcriptional Regulation in Prostate Cancer.

scientific article published on 12 March 2018

Transcriptional landscape of the human cell cycle.

scientific article published on 13 March 2017

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts

scientific article

Twenty years of menin: emerging opportunities for restoration of transcription in MEN1.

scientific article published on 15 August 2017

Unique ERalpha cistromes control cell type-specific gene regulation

scientific article published on 25 September 2008

Unraveling estrogen action in osteoporosis

scientific article published on 29 February 2008

Unraveling the clinicopathological features driving the emergence of mutations in metastatic breast cancer

VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis

scientific article published on 12 April 2018

Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells

scientific article published on 27 February 2017

X chromosomal abnormalities in basal-like human breast cancer

scientific article

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

scientific article

p16<sup>INK4A</sup>-deficiency predicts response to combined HER2 and CDK4/6 inhibition in HER2+ breast cancer brain metastases

scientific article published on 18 March 2022

p300 is a component of an estrogen receptor coactivator complex

scientific article published on October 1996

p63 regulates an adhesion programme and cell survival in epithelial cells

scientific article published on 21 May 2006

xMAN: extreme MApping of OligoNucleotides

scientific article

β-Catenin Is a Useful Adjunct Immunohistochemical Marker for the Diagnosis of Pulmonary Lymphangioleiomyomatosis

scientific article published on 01 May 2011

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