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List of works by Marcel Kaiser

(2R,1'S,2'R)- and (2S,1'S,2'R)-3-[2-Mono(di,tri)fluoromethylcyclopropyl]alanines and their incorporation into hormaomycin analogues

scientific article published on 3 December 2014

(±)-Alternarlactones A and B, Two Antiparasitic Alternariol-like Dimers from the Fungus Alternaria alternata P1210 Isolated from the Halophyte Salicornia sp

scientific article published on 27 August 2019

(±)-trans-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: Synthesis, in vitro evaluation and SAR analysis

scientific article published on 23 July 2020

1,2-substituted 4-(1H)-quinolones: synthesis, antimalarial and antitrypanosomal activities in vitro.

scientific article published on 10 September 2014

1-Aryl-1,2,3,4-tetrahydroisoquinolines as potential antimalarials: synthesis, in vitro antiplasmodial activity and in silico pharmacokinetics evaluation

scholarly article in RSC Advances, vol. 4 no. 44, 2014

1-Aryl-4-nitro-1H-imidazoles, a new promising series for the treatment of human African trypanosomiasis

article published in 2011

2 H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design

scientific article published on 06 April 2018

2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities

scientific article

2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymes

scientific article

2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile.

scientific article published on 3 August 2015

3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis.

scientific article published on 16 May 2013

3-Nitrotriazole-based piperazides as potent antitrypanosomal agents.

scientific article published on 4 September 2015

4-Aminobicyclo[2.2.2]octan-2-ones and -ols via Enamine Intermediates

article

4-Aminobicyclo[2.2.2]octan-2-yl 4-aminobutanoates with antiprotozoal activity

6-Arylpyrazine-2-carboxamides: A New Core for Trypanosoma brucei Inhibitors

scientific article published on 6 August 2015

8,8-Dialkyldihydroberberines with Potent Antiprotozoal Activity

8,8-dialkyldihydroberberines with potent antiprotozoal activity

article published in 2013

9β-hydroxyparthenolide esters from Inula montbretiana and their antiprotozoal activity

scientific article

A Modular Approach to the Antifungal Sphingofungin Family: Concise Total Synthesis of Sphingofungin A and C

scientific article published in 2021

A Near-Complete Series of Four Atropisomeric Jozimine A2-Type Naphthylisoquinoline Dimers with Antiplasmodial and Cytotoxic Activities and Related Alkaloids from Ancistrocladus abbreviatus

scientific article published on 23 October 2019

A New Alkamide with an Endoperoxide Structure from Acmella ciliata (Asteraceae) and Its in Vitro Antiplasmodial Activity.

scientific article published on 11 June 2016

A Photorhabdus natural product inhibits insect juvenile hormone epoxide hydrolase

scientific article published on 25 February 2015

A Sample-Centric and Knowledge-Driven Computational Framework for Natural Products Drug Discovery ⬇️

A bioactive biflavonoid from Campnosperma panamense

scholarly article by B. Weniger et al published December 2004 in Fitoterapia

A new antifungal and antiprotozoal bibenzyl derivative from Gavilea lutea

scientific article published on 8 June 2017

A new chemotype with promise against Trypanosoma cruzi

scientific article published on 31 October 2019

A new nonpolar N-hydroxy imidazoline lead compound with improved activity in a murine model of late-stage Trypanosoma brucei brucei infection is not cross-resistant with diamidines

scientific article

A protocol for HPLC-based activity profiling for natural products with activities against tropical parasites

scientific article

Abietane-Type Diterpenoid Amides with Highly Potent and Selective Activity against Leishmania donovani and Trypanosoma cruzi.

scientific article published on 5 February 2016

Acid-Induced Rearrangement of Epoxygermacranolides: Synthesis of Furanoheliangolides and Cadinanes from Nobilin.

scientific article published on 18 December 2017

Actinoallolides A-E, new anti-trypanosomal macrolides, produced by an endophytic actinomycete, Actinoallomurus fulvus MK10-036.

scientific article published on 30 January 2015

Activity of diimidazoline amides against African trypanosomiasis

scientific article

Activity of diphenyl ether benzyl amines against Human African Trypanosomiasis

scientific article published on 27 January 2020

Acyclic Nucleoside Analogues as Inhibitors ofPlasmodiumfalciparumdUTPase

scientific article published on 01 July 2006

Acyl derivatives of 5-amino-2-azabicyclo[3.2.2]nonanes

article

Adenosine Kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics

scientific article

Agrochemicals against malaria, sleeping sickness, leishmaniasis and Chagas disease

scientific article

Alkaloid Constituents of the Amaryllidaceae Plant Amaryllis belladonna L.

scientific article published on 31 August 2017

Alkamides from Anacyclus pyrethrum L. and Their in Vitro Antiprotozoal Activity.

scientific article published on 12 May 2017

Alkanediamide-Linked Bisbenzamidines Are Promising Antiparasitic Agents.

scientific article published on 19 April 2016

Alkyl and dialkylaminoethyl derivatives of 5-amino-2-azabicyclo[3.2.2]nonanes and their antiplasmodial and antitrypanosomal activities

scientific article published on 30 September 2009

Aminoalkyl Derivatives of Guanidine Diaromatic Minor Groove Binders with Antiprotozoal Activity

scientific article

An Alba-domain protein required for proteome remodelling during trypanosome differentiation and host transition

scientific article published on 25 January 2021

An Unusually Broad Series of Seven Cyclombandakamines, Bridged Dimeric Naphthylisoquinoline Alkaloids from the Congolese Liana Ancistrocladus ealaensis

scientific article published on 08 July 2019

An unusual dimeric guaianolide with antiprotozoal activity and further sesquiterpene lactones from Eupatoriumperfoliatum

scientific article published on 15 February 2011

Analogues of thiolactomycin as potential antimalarial agents

scientific article published on September 2005

Ancistectorine D, a naphthylisoquinoline alkaloid with antiprotozoal and antileukemic activities, and further 5,8'- and 7,1'-linked metabolites from the Chinese liana Ancistrocladus tectorius.

scientific article published on 16 September 2016

Ancistrobrevines E-J and related naphthylisoquinoline alkaloids from the West African liana Ancistrocladus abbreviatus with inhibitory activities against Plasmodium falciparum and PANC-1 human pancreatic cancer cells

scientific article published on 09 November 2018

Anti-Protozoal Activities of Cembrane-Type Diterpenes from Vietnamese Soft Corals.

scientific article published on 8 July 2015

Anti-Trypanosomal Proteasome Inhibitors Cure Hemolymphatic and Meningoencephalic Murine Infection Models of African Trypanosomiasis

scientific article published on 17 February 2020

Anti-Trypanosomatid Elemanolide Sesquiterpene Lactones from Vernonia lasiopus O. Hoffm.

scientific article

Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian Aplidium scabellum

scientific article published on 3 October 2011

Anti-trypanosomal cadinanes synthesized by transannular cyclization of the natural sesquiterpene lactone nobilin

scientific article published on 13 February 2015

Antikinetoplastid antimitotic activity and metabolic stability of dinitroaniline sulfonamides and benzamides

scientific article published on 3 May 2006

Antileishmanial activity of 12-methoxycarnosic acid from Salvia repens Burch. ex Benth. (Lamiaceae)

scientific article published in 2014

Antileukemic ancistrobenomine B and related 5,1'-coupled naphthylisoquinoline alkaloids from the Chinese liana Ancistrocladus tectorius.

scientific article

Antimalarial and antitubercular nostocarboline and eudistomin derivatives: synthesis, in vitro and in vivo biological evaluation

scientific article published on 11 January 2010

Antimalarial pyrido[1,2-a]benzimidazoles

scientific article published on 16 June 2011

Antimalarial β-carbolines from the New Zealand ascidian Pseudodistoma opacum

scientific article published on 16 August 2011

Antimycobacterial, antiprotozoal and cytotoxic potential of twenty-one brown algae (Phaeophyceae) from British and Irish waters.

scientific article published on November 2010

Antiparasitic agents: new drugs on the horizon

scientific article published on 29 May 2012

Antiparasitic chaiyaphumines from entomopathogenic Xenorhabdus sp. PB61.4.

scientific article published on 27 March 2014

Antiparasitic compounds from Cupania cinerea with activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense

scientific article published on 25 March 2011

Antiplasmodial Ealapasamines A-C,'Mixed' Naphthylisoquinoline Dimers from the Central African Liana Ancistrocladus ealaensis.

scientific article published on 18 July 2017

Antiplasmodial and antitrypanosomal activities of aminobicyclo[2.2.2]octyl omega-aminoalkanoates

scientific article published on 10 May 2008

Antiplasmodial and antitrypanosomal activity of bicyclic amides and esters of dialkylamino acids

article

Antiplasmodial and antitrypanosomal activity of new esters and ethers of 4-dialkylaminobicyclo[2.2.2]octan-2-ols

scientific article published on 18 April 2006

Antiplasmodial and antitrypanosomal activity of pyrethrins and pyrethroids

scientific article

Antiplasmodial and antitrypanosomal activity of tanshinone-type diterpenoids from Salvia miltiorrhiza.

scientific article published on 16 March 2011

Antiplasmodial and leishmanicidal activity of biflavonoids from Indian Selaginella bryopteris

article published in 2008

Antiplasmodial lanostanes from the Ganoderma lucidum mushroom

scientific article published in May 2010

Antiprotozoal Activities of Epimeric Aminobicycles

Antiprotozoal Activities of Epimeric Aminobicycles

Antiprotozoal Activities of Tetrazole-quinolines with Aminopiperidine Linker

article

Antiprotozoal Activity Profiling of Approved Drugs: A Starting Point toward Drug Repositioning

scientific article

Antiprotozoal Activity of Plants Used in the Management of Sleeping Sickness in Angola and Bioactivity-Guided Fractionation of Brasenia schreberi J.F.Gmel and Nymphaea lotus L. Active against T. b. rhodesiense

scientific article published on 3 April 2024

Antiprotozoal Activity of Turkish Origanum onites Essential Oil and Its Components

scientific article published on 03 December 2019

Antiprotozoal Activity-Based Profiling of a Dichloromethane Extract from Anthemis nobilis Flowers.

scientific article published on 24 January 2017

Antiprotozoal Diterpenes from Perovskia abrotanoides.

scientific article published on 26 April 2018

Antiprotozoal Germacranolide Sesquiterpene Lactones from Tanacetum sonbolii

scientific article published on 08 January 2019

Antiprotozoal Isoprenoids from Salvia hydrangea

scientific article published on 19 December 2018

Antiprotozoal Linear Furanosesterterpenoids from the Marine Sponge Ircinia oros.

scientific article

Antiprotozoal Selectivity of Diimidazoline N-Phenylbenzamides

scientific article published on 16 January 2015

Antiprotozoal Sesquiterpene Lactones and Other Constituents from Tarchonanthus camphoratus and Schkuhria pinnata.

scientific article published on 15 December 2017

Antiprotozoal activities of new bicyclo[2.2.2]octan-2-imines and esters of bicyclo[2.2.2]octan-2-ols

scientific article published on 29 December 2004

Antiprotozoal activities of new bis-chlorophenyl derivatives of bicyclic octanes and aza-nonanes

scientific article published on 2 August 2006

Antiprotozoal activities of organic extracts from French marine seaweeds

scientific article published on 25 May 2011

Antiprotozoal activities of some constituents of Markhamia tomentosa (Bignoniaceae).

scientific article published on July 2010

Antiprotozoal activities of traditional medicinal plants from the Garhwal region of North West Himalaya, India

scientific article published on 16 April 2011

Antiprotozoal activity and DNA binding of N-substituted N-phenylbenzamide and 1,3-diphenylurea bisguanidines

scientific article

Antiprotozoal activity and DNA binding of dicationic acridones

scientific article published on 16 February 2015

Antiprotozoal activity of (E)-cinnamic N-acylhydrazone derivatives

scientific article published on 5 December 2014

Antiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives

scientific article published on 29 June 2009

Antiprotozoal activity of Achillea ptarmica (Asteraceae) and its main alkamide constituents. ⬇️

scientific article published on 20 May 2014

Antiprotozoal activity of Buxus sempervirens and activity-guided isolation of O-tigloylcyclovirobuxeine-B as the main constituent active against Plasmodium falciparum.

scientific article published on 15 May 2014

Antiprotozoal activity of Melampyrum arvense and its metabolites

scientific article published on 01 January 2011

Antiprotozoal activity of bicycles featuring a dimethylamino group at their bridgehead.

scientific article published on 14 June 2016

Antiprotozoal activity of bicyclic diamines with a N-methylpiperazinyl group at the bridgehead atom

scientific article published on 2 July 2013

Antiprotozoal activity of dehydroabietic acid derivatives against Leishmania donovani and Trypanosoma cruzi

Antiprotozoal activity of diterpenoids isolated from Zhumeria majdae- absolute configuration by circular dichroism

scientific article published on 11 May 2020

Antiprotozoal alkaloids from Galanthus trojanus

Antiprotozoal and antihelminthic properties of plants ingested by wild Japanese macaques (Macaca fuscata yakui) in Yakushima Island

scientific article published on 04 October 2019

Antiprotozoal and cysteine proteases inhibitory activity of dipeptidyl enoates

scientific article published on 10 July 2018

Antiprotozoal isoflavan quinones from Abrus precatorius ssp. africanus

scientific article

Antiprotozoal screening of 60 South African plants, and the identification of the antitrypanosomal germacranolides schkuhrin I and II.

scientific article

Antiprotozoal steroidal saponins from the marine sponge Pandaros acanthifolium ⬇️

scientific article published on August 2010

Antiprotozoal, antimycobacterial and cytotoxic potential of some british green algae

scientific article

Antiprotozoal, antimycobacterial and cytotoxic potential of twenty-three British and Irish red algae

scientific article

Antiprotozoal, antitubercular and cytotoxic potential of cyanobacterial (blue-green algal) extracts from Ireland.

scientific article published on May 2011

Antitrypanosomal Activity of Sesquiterpene Lactones from L. Including a New Furanoheliangolide with an Unusual Structure

scientific article published on 18 March 2019

Antitrypanosomal activity of 1,2-dihydroquinolin-6-ols and their ester derivatives

scientific article published in February 2010

Antitrypanosomal activity of 5-nitro-2-aminothiazole-based compounds

scientific article published on 08 April 2016

Antitrypanosomal activity of fexinidazole, a new oral nitroimidazole drug candidate for treatment of sleeping sickness

scientific article published on 12 September 2011

Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies

scientific article

Antitrypanosomal isoflavan quinones from Abrus precatorius

scientific article published on 29 December 2013

Antitrypanosomal isothiocyanate and thiocarbamate glycosides from Moringa peregrina

scientific article

Antitrypanosomal quinoline alkaloids from the roots of Waltheria indica

scientific article published on 14 October 2014

Antitrypanosomal sesquiterpene lactones from Saussurea costus

scientific article published on 23 May 2011

Antitrypanosomal structure-activity-relationship study of synthetic cynaropicrin derivatives

scientific article published on 2 January 2014

Antitrypanosomal triterpenoid with an ε-lactone E-ring from Salvia urmiensis

scientific article published on 5 September 2013

Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol

scientific article (publication date: 2013)

Assessing anti-T. cruzi candidates in vitro for sterile cidality

scientific article published on 26 August 2016

Assessment of anti-protozoal activity of plants traditionally used in Ecuador in the treatment of leishmaniasis

scientific article

Assessment of dual life stage antiplasmodial activity of british seaweeds

scientific article published on 22 October 2013

Balgacyclamides, antiplasmodial heterocyclic peptides from Microcystis aeruguinosa EAWAG 251. ⬇️

scientific article published on 6 January 2014

Betraying the parasite's redox system: diaryl sulfide-based inhibitors of trypanothione reductase: subversive substrates and antitrypanosomal properties

scientific article

Bicyclic amido compounds with antiprotozoal activity

Bicyclo[2.2.2]octyl esters of dialkylamino acids as antiprotozoals

scientific article published on 23 May 2007

Bifurcatriol, a New Antiprotozoal Acyclic Diterpene from the Brown Alga Bifurcaria bifurcata

scientific article

Binding to large enzyme pockets: small-molecule inhibitors of trypanothione reductase

scientific article

Bioactive derivatives of isopropylstilbene from mutasynthesis and chemical synthesis

scientific article published on 24 October 2014

Biological Evaluation and X-ray Co-crystal Structures of Cyclohexylpyrrolidine Ligands for Trypanothione Reductase, an Enzyme from the Redox Metabolism of Trypanosoma.

scientific article published on 6 April 2018

Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents

scientific article published on 28 June 2018

Biosynthesis and function of simple amides in Xenorhabdus doucetiae.

scientific article published on 11 September 2017

Biosynthesis of the Antibiotic Nematophin and Its Elongated Derivatives in Entomopathogenic Bacteria.

scientific article published on 30 January 2017

Bis(oxyphenylene)benzimidazoles: a novel class of anti-Plasmodium falciparum agents.

scientific article

Bromopyrrole alkaloids as lead compounds against protozoan parasites

scientific article

C-H Activation Enables a Concise Total Synthesis of Quinine and Analogues with Enhanced Antimalarial Activity

scientific article published on 22 June 2018

C-H-Aktivierung ermöglicht eine kurze Totalsynthese von Chinin und Analoga mit erhöhter Anti-Malaria-Aktivität

scholarly article by Daniel H. O' Donovan et al published 22 June 2018 in Angewandte Chemie

Characterisation of taxlllaids A-G; natural products from Xenorhabdus indica.

scientific article

Characterization of a melamino nitroheterocycle as a potential lead for the treatment of human african trypanosomiasis

scientific article

ChemInform Abstract: Characterization of Taxlllaids A-G; Natural Products from Xenorhabdus indica

ChemInform Abstract: Diarylcyclohexanones: Synthons for New Bicyclic Compounds

article

ChemInform Abstract: Epimers of Bicyclo[2.2.2]octan-2-ol Derivatives with Antiprotozoal Activity

article

ChemInform Abstract: Potent and Selective Antiplasmodial Activity of the Cyanobacterial Alkaloid Nostocarboline and Its Dimers

ChemInform Abstract: Synthesis and Antiprotozoal Activities of Simplified Analogues of Naphthylisoquinoline Alkaloids

ChemInform Abstract: Synthesis and Evaluation of 2-Pyridyl Pyrimidines with in vitro Antiplasmodial and Antileishmanial Activity

ChemInform Abstract: Synthesis and anti-Protozoal Activity of Novel Dihydropyrrolo[3,4-d][1,2,3]triazoles

ChemInform Abstract: Synthesis, Crystal Structure, and in vitro Antiprotozoal Activity of Some 5-Phenyl(methyl)sulfonyl-substituted Dihydroisoxazoles

Chemical constituents from Waltheria indica exert in vitro activity against Trypanosoma brucei and T. cruzi.

scientific article published on 11 June 2015

Chloroquine-astemizole hybrids with potent in vitro and in vivo antiplasmodial activity

scientific article published on 18 November 2008

Combined Approach of Backbone Amide Linking and On-Resin N-Methylation for the Synthesis of Bioactive and Metabolically Stable Peptides

scientific article published on 20 April 2018

Comparative antiplasmodial, leishmanicidal and antitrypanosomal activities of several biflavonoids.

scientific article published on 28 June 2005

Complementary Quantitative Structure⁻Activity Relationship Models for the Antitrypanosomal Activity of Sesquiterpene Lactones

scientific article published on 22 November 2018

Complete structural assignment of serratol, a cembrane-type diterpene from Boswellia serrata, and evaluation of its antiprotozoal activity

scientific article published on 14 December 2010

Conjugation of quinones with natural polyamines: toward an expanded antitrypanosomatid profile

scientific article

Correction: Identification of Compounds with Anti-Proliferative Activity against Strain 427 by a Whole Cell Viability Based HTS Campaign

Cover Feature: Precursor-Directed Diversification of Cyclic Tetrapeptidic Pseudoxylallemycins (ChemBioChem 21/2018)

scientific article published in 2018

Cupiennin 1a exhibits a remarkably broad, non-stereospecific cytolytic activity on bacteria, protozoan parasites, insects, and human cancer cells

scientific article

Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections

scientific article published on 29 June 2023

Cynaropicrin targets the trypanothione redox system in Trypanosoma brucei

scientific article published on 5 September 2013

Cynaropicrin: the first plant natural product with in vivo activity against Trypanosoma brucei

scientific article

Cytotoxic and haemolytic steroidal glycosides from the Caribbean sponge Pandaros acanthifolium

scientific article

DMSO-mediated ligand dissociation: renaissance for biological activity of N-heterocyclic-[Ru(η6-arene)Cl2] drug candidates.

scientific article published on 2 October 2013

DNA Binding Affinity of Bisguanidine and Bis(2-aminoimidazoline) Derivatives with in Vivo Antitrypanosomal Activity

scientific article published on 01 June 2006

Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target

scientific article published in September 2005

Design and preparation of sterol mimetics as potential antiparasitics

scientific article published on 9 August 2010

Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents

scientific article

Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents

scientific article published on 23 January 2019

Design, synthesis and evaluation of novel uracil acetamide derivatives as potential inhibitors of Plasmodium falciparum dUTP nucleotidohydrolase.

scientific article published on 10 July 2008

Design, synthesis and evaluation of novel uracil amino acid conjugates for the inhibition of Trypanosoma cruzi dUTPase.

scientific article published on 3 May 2006

Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase

scientific article

Design, synthesis, and in vitro cancer cell growth inhibition evaluation and antimalarial testing of trioxanes installed in cyclic 2-enoate substructures.

scientific article published on 13 August 2013

Development of a Focused Library of Triazole-Linked Privileged-Structure-Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections.

scientific article published on 16 February 2018

Dialkylaminoalkyl derivatives of bicyclic compounds with antiplasmodial activity

article

Diaryl sulfide-based inhibitors of trypanothione reductase: inhibition potency, revised binding mode and antiprotozoal activities

scientific article

Diarylcyclohexanones: synthons for new bicyclic compounds

Didemnidines A and B, Indole Spermidine Alkaloids from the New Zealand AscidianDidemnumsp

article

Dioncophyllines C2, D2, and F and Related Naphthylisoquinoline Alkaloids from the Congolese Liana Ancistrocladus ileboensis with Potent Activities against Plasmodium falciparum and against Multiple Myeloma and Leukemia Cell Lines.

scientific article published on 25 January 2017

Dipeptidyl Enoates As Potent Rhodesain Inhibitors That Display a Dual Mode of Action

scientific article published on 14 July 2015

Directed Synthesis of All Four Pure Stereoisomers of the N,C-Coupled Naphthylisoquinoline Alkaloid Ancistrocladinium A.

scientific article

Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease

scientific article published on 05 March 2020

Discovery and evaluation of thiazinoquinones as anti-protozoal agents

scientific article published on 09 September 2013

Discovery and optimisation studies of antimalarial phenotypic hits.

scientific article published on 9 September 2015

Discovery and preliminary structure-activity relationship analysis of 1,14-sperminediphenylacetamides as potent and selective antimalarial lead compounds

scientific article published on 29 November 2012

Discovery and structure-activity relationships of pyrrolone antimalarials

scientific article

Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitro

scientific article published on 22 October 2018

Discovery of 4-((1-(1H-imidazol-2-yl)alkoxy)methyl)pyridines as a new class of Trypanosoma cruzi growth inhibitors

scientific article published on 22 February 2020

Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase Library

scientific article published on 18 September 2015

Discovery of Novel Benzo[a]phenoxazine SSJ-183 as a Drug Candidate for Malaria

scientific article

Discovery of a quinoline-based phenyl sulfone derivative as an antitrypanosomal agent.

scientific article published on 24 March 2018

Discovery of nitroheterocycles active against African trypanosomes. In vitro screening and preliminary SAR studies

scientific article

Discovery of novel orally bioavailable oxaborole 6-carboxamides that demonstrate cure in a murine model of late-stage central nervous system african trypanosomiasis

scientific article

Discovery of potent nitrotriazole-based antitrypanosomal agents: In vitro and in vivo evaluation

scientific article published on 24 August 2015

Disesquiterpene and sesquiterpene coumarins from Ferula pseudalliacea, and determination of their absolute configurations

scientific article published on 20 March 2012

Diversity of exophillic acid derivatives in strains of an endophytic Exophiala sp.

scientific article

Diversity-oriented synthesis yields a new drug lead for treatment of chagas disease

scientific article

EFFECTS ON FITNESS COMPONENTS OF P-ELEMENT INSERTS IN DROSOPHILA MELANOGASTER : ANALYSIS OF TRADE-OFFS

scientific article published on 01 April 1996

Ealamines A-H, a Series of Naphthylisoquinolines with the Rare 7,8'-Coupling Site, from the Congolese Liana Ancistrocladus ealaensis, Targeting Pancreatic Cancer Cells

scientific article published on 20 October 2019

Effects on fitness components of enhanced expression of elongation factor EF-1alpha in Drosophila melanogaster. I. The contrasting approaches of molecular and population biologists

scientific article published in December 1993

Eleganolone, a diterpene from the French marine alga Bifurcaria bifurcata inhibits growth of the human pathogens Trypanosoma brucei and Plasmodium falciparum

scientific article published on 26 February 2013

Enantiospecific antitrypanosomal in vitro activity of eflornithine

scientific article published on 12 July 2021

Encecalol angelate, an unstable chromene from Ageratum conyzoides L.: total synthesis and investigation of its antiprotozoal activity

scientific article published on 17 June 2011

Entomopathogenic bacteria use multiple mechanisms for bioactive peptide library design.

scientific article

Epimers of bicyclo[2.2.2]octan-2-ol derivatives with antiprotozoal activity

scientific article

Erratum: Terpenoids from the Oleo-Gum-Resin of Boswellia serrata and Their Antiplasmodial Effects In Vitro

scientific article published on 28 August 2017

Evaluating 5-Nitrothiazoles as Trypanocidal Agents

scientific article

Evaluation of Alkanediamide-Linked Bisbenzamidines as Potential Antiparasitic Agents

Evaluation of Turkish seaweeds for antiprotozoal, antimycobacterial and cytotoxic activities

scientific article published on 12 November 2010

Evaluation of in vitro antiprotozoal activity of Ajuga laxmannii and its secondary metabolites

scientific article published on 6 January 2016

Evaluation of the in vitro trypanocidal activity of methylated flavonoid constituents of Vitex simplicifolia leaves

scientific article published on 26 March 2015

Expanding the Rubterolone Family: Intrinsic Reactivity and Directed Diversification of PKS-derived Pyrans

Experimental evolution of aging, growth, and reproduction in fruitflies

scientific article

Fabclavines: bioactive peptide-polyketide-polyamino hybrids from Xenorhabdus

scientific article published on 13 February 2014

Facile Synthesis of Cyclohexanediones and Dialkylresorcinols - Bioactive Natural Products from Entomopathogenic Bacteria

article published in 2014

Fexinidazole for Human African Trypanosomiasis, the Fruit of a Successful Public-Private Partnership

scientific article published on 17 October 2022

Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness

scientific article

Fluorinated rhodacyanine (SJL-01) possessing high efficacy for visceral leishmaniasis (VL).

scientific article

Genetic reconstruction of protozoan rRNA decoding sites provides a rationale for paromomycin activity against Leishmania and Trypanosoma

scientific article

Georatusin, a Specific Antiparasitic Polyketide–Peptide Hybrid from the Fungus Geomyces auratus

scientific article published on 23 February 2018

HPLC-Based Activity Profiling for Antiprotozoal Compounds in Croton gratissimus and Cuscuta hyalina ⬇️

scientific article published on 14 August 2020

HPLC-based activity profiling for antiplasmodial compounds in the traditional Indonesian medicinal plant Carica papaya L.

scientific article

HPLC-profiling for antiplasmodial compounds—3-Methoxycarpachromene from Pistacia atlantica

article published in 2009

Harnessing fungal nonribosomal cyclodepsipeptide synthetases for mechanistic insights and tailored engineering

scientific article published on 25 September 2017

Highly antiplasmodial non-natural oxidative products of dioncophylline A: synthesis, absolute configuration, and conformational stability

scientific article published on 13 August 2015

Hippeastrum reticulatum (Amaryllidaceae): Alkaloid Profiling, Biological Activities and Molecular Docking.

scientific article published on 9 December 2017

Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides

scientific article published on 22 August 2016

Hydrazones and new Oximes of 4-Aminobicyclo[2.2.2]octanones and their Antiprotozoal Activities

Identification and Characterization of FTY720 for the Treatment of Human African Trypanosomiasis

scientific article published on 14 December 2015

Identification and optimization of an aminoalcohol-carbazole series with antimalarial properties

scientific article

Identification of 1,3-diiminoisoindoline carbohydrazides as potential antimalarial candidates

scientific article

Identification of Diversity-Oriented Synthesis Derived Small Molecule, ML341, with Cidal Activity Against Trypanosoma cruzi

scientific article published on 31 January 2014

Identification of a new chemical class of antimalarials

scientific article

Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign

scientific article

Identification of two new phenathrenones and a saponin as antiprotozoal constituents of Drypetes gerrardii

Improved Inhibitors of Trypanothione Reductase by Combination of Motifs: Synthesis, Inhibitory Potency, Binding Mode, and Antiprotozoal Activities

scientific article published on 16 December 2010

In Silico Identification and in Vitro Activity of Novel Natural Inhibitors of Trypanosoma brucei Glyceraldehyde-3-phosphate-dehydrogenase.

scientific article published on 3 September 2015

In Silico prediction and experimental evaluation of furanoheliangolide sesquiterpene lactones as potent agents against Trypanosoma brucei rhodesiense

scientific article

In Vitro Drug Efficacy Testing Against Trypanosoma brucei

scientific article published on 01 January 2020

In pursuit of natural product leads: synthesis and biological evaluation of 2-[3-hydroxy-2-[(3-hydroxypyridine-2-carbonyl)amino]phenyl]benzoxazole-4-carboxylic acid (A-33853) and its analogues: discovery of N-(2-benzoxazol-2-ylphenyl)benzamides as n

scientific article

In vitro antiplasmodial screening of ethnopharmacologically selected South African plant species used for the treatment of malaria

scientific article

In vitro antiprotozoal activities and cytotoxicity of some selected Cameroonian medicinal plants

scientific article published on 10 November 2006

In vitro antiprotozoal activity of extracts of five Turkish Lamiaceae species

scientific article published on November 1, 2011

In vitro antiprotozoal activity of the lipophilic extracts of different parts of Turkish Pistacia vera L.

scientific article published on 14 November 2005

In vitro screening of traditional South African malaria remedies against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, and Plasmodium falciparum

scientific article published on 16 March 2011

In vitroantileishmanial, antiplasmodial and cytotoxic activities of a new ventiloquinone and five known triterpenes fromParinari excelsa

scientific article published on 03 April 2012

Indoloditerpenes from a marine-derived fungal strain of Dichotomomyces cejpii with antagonistic activity at GPR18 and cannabinoid receptors

scientific article published on 28 January 2014

Inhibiting enoyl-ACP reductase (FabI) across pathogenic microorganisms by linear sesquiterpene lactones from Anthemis auriculata.

scientific article

Inhibition of trypanosome alternative oxidase without its N-terminal mitochondrial targeting signal (ΔMTS-TAO) by cationic and non-cationic 4-hydroxybenzoate and 4-alkoxybenzaldehyde derivatives active against T. brucei and T. congolense.

scientific article published on 26 February 2018

Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.

scientific article published on March 2017

Inhibitors of adenosine consuming parasites through polymer-assisted N-acylation of N6-substituted 5'-amino-5'-deoxyadenosines.

scientific article published on 26 June 2009

Inhibitors of adenosine consuming parasites through polymer-assisted solution phase synthesis of lipophilic 5'-amido-5'-deoxyadenosine derivatives

scientific article published on 20 January 2009

Inhibitory activity of marine sponge-derived natural products against parasitic protozoa

scientific article

Insect-specific production of new GameXPeptides in photorhabdus luminescens TTO1, widespread natural products in entomopathogenic bacteria

scientific article published on 25 November 2014

Inside Cover: Fabclavines: Bioactive Peptide-Polyketide-Polyamino Hybrids fromXenorhabdus(ChemBioChem 4/2014)

scholarly article by Sebastian W. Fuchs published in February 2014

Investigation of Antiplasmodial Effects of Terpenoid Compounds Isolated from Myrrh

scientific article published on 04 May 2020

Investigation of acyclic uridine amide and 5'-amido nucleoside analogues as potential inhibitors of the Plasmodium falciparum dUTPase.

scientific article published on 12 July 2013

Investigation of indolglyoxamide and indolacetamide analogues of polyamines as antimalarial and antitrypanosomal agents

scientific article

Isolation and Structural Elucidation of Compounds from Pleiocarpa bicarpellata and Their In Vitro Antiprotozoal Activity

scientific article published on 30 March 2022

Isolation of Trypanosoma brucei gambiense from cured and relapsed sleeping sickness patients and adaptation to laboratory mice

scientific article

Isolation of aerucyclamides C and D and structure revision of microcyclamide 7806A: heterocyclic ribosomal peptides from Microcystis aeruginosa PCC 7806 and their antiparasite evaluation

scientific article

Isomerization of 4-Amino-6,7-diphenylbicyclo[2.2.2]octan-2-ones

article

Isomerization of 4-amino-6,7-diphenylbicyclo[2.2.2]octan-2-ones

Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound

scientific article published on May 2005

Jacaranone-derived glucosidic esters from Jacaranda glabra and their activity against Plasmodium falciparum

scientific article published in April 2010

Jozilebomines A and B, Naphthylisoquinoline Dimers from the Congolese Liana Ancistrocladus ileboensis, with Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Cell Line.

scientific article

Larrea tridentata—Absolute configuration of its epoxylignans and investigations on its antiprotozoal activity

Lead selection of antiparasitic compounds from a focused library of benzenesulfonyl derivatives of heterocycles

scientific article

Leishmanicidal and cholinesterase inhibiting activities of phenolic compounds from Allanblackia monticola and Symphonia globulifera. ⬇️

scientific article published on 20 July 2007

Lignans, Amides, and Saponins from Haplophyllum tuberculatum and Their Antiprotozoal Activity ⬇️

scientific article published on 19 June 2020

Lycopodium clavatum and Lycopodium complanatum subsp. chamaecyparissus ekstrelerinin antiprotozoal aktivitesi ve sitotoksisitesi

MEMO: Mass Spectrometry-Based Sample Vectorization to Explore Chemodiverse Datasets

scientific article published on 13 April 2022

Machine learning prioritizes synthesis of primaquine ureidoamides with high antimalarial activity and attenuated cytotoxicity

scientific article published on 31 January 2018

Macyranones: Structure, Biosynthesis, and Binding Mode of an Unprecedented Epoxyketone that Targets the 20S Proteasome

scientific article

Manadoperoxides, a new class of potent antitrypanosomal agents of marine origin

scientific article

Match-making for posaconazole through systems thinking

scientific article published on 6 December 2014

Mbandakamine-Type Naphthylisoquinoline Dimers and Related Alkaloids from the Central African Liana Ancistrocladus ealaensis with Antiparasitic and Antileukemic Activities.

scientific article published on 21 March 2018

Methionine-Containing Rhabdopeptide/Xenortide-like Peptides from Heterologous Expression of the Biosynthetic Gene Cluster kj12ABC in Escherichia coli

article

Mining Sudanese Medicinal Plants for Antiprotozoal Agents

scientific article published on 09 June 2020

Modified 5'-trityl nucleosides as inhibitors of Plasmodium falciparum dUTPase

scientific article published on 18 January 2011

Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin.

scientific article published on January 2010

Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule.

scientific article

N-oxide alkaloids from Crinum amabile (Amaryllidaceae).

scientific article

N-substituted noscapine derivatives as new antiprotozoal agents: Synthesis, antiparasitic activity and molecular docking study

scientific article published on 11 July 2019

Natural and semisynthetic analogues of manadoperoxide B reveal new structural requirements for trypanocidal activity

scientific article published on 28 August 2013

Natural product inhibitors of fatty acid biosynthesis: synthesis of the marine microbial metabolites pseudopyronines A and B and evaluation of their anti-infective activities

New 4-Amino-2-azabicyclo[3.2.2]nonane Derivatives and Their Antiprotozoal Potencies

article

New 4-Amino-2-azabicyclo[3.2.2]nonane Derivatives and their Antiprotozoal Potencies

New N-methylpiperazinyl derivatives of bicyclic antiprotozoal compounds

scientific article published on 18 November 2011

New Promising Compounds with in Vitro Nanomolar Activity against Trypanosoma cruzi

scientific article published on 7 May 2013

New bis(2-aminoimidazoline) and bisguanidine DNA minor groove binders with potent in vivo antitrypanosomal and antiplasmodial activity

scientific article published on 5 February 2008

New derivatives of 7-chloroquinolin-4-amine with antiprotozoal activity.

scientific article published on 18 December 2016

New derivatives of bicyclic diamines with antiprotozoal activity

New derivatives of quinoline-4-carboxylic acid with antiplasmodial activity

scientific article published on 24 February 2017

Nitrotriazole-based acetamides and propanamides with broad spectrum antitrypanosomal activity.

scientific article published on 09 August 2016

Non-invasive monitoring of drug action: A new live in vitro assay design for Chagas' disease drug discovery

scientific article published on 27 July 2020

Novel 3-nitro-1H-1,2,4-triazole-based aliphatic and aromatic amines as anti-chagasic agents

scientific article

Novel 3-nitro-1H-1,2,4-triazole-based amides and sulfonamides as potential antitrypanosomal agents

scientific article published on 23 May 2012

Novel 3-nitro-1H-1,2,4-triazole-based compounds as potential anti-Chagasic drugs: in vivo studies

scientific article published on October 2013

Novel 3-nitro-1H-1,2,4-triazole-based piperazines and 2-amino-1,3-benzothiazoles as antichagasic agents

scientific article published on 20 August 2013

Novel 3-nitrotriazole-based amides and carbinols as bifunctional antichagasic agents

scientific article

Novel S-adenosylmethionine decarboxylase inhibitors for the treatment of human African trypanosomiasis

scientific article published on 16 March 2009

Novel azabicyclo[3.2.2]nonane derivatives and their activities against Plasmodium falciparum K1 and Trypanosoma brucei rhodesiense

scientific article published on 7 May 2008

Novel functionalized melamine-based nitroheterocycles: synthesis and activity against trypanosomatid parasites

scientific article

Novel nitro(triazole/imidazole)-based heteroarylamides/sulfonamides as potential antitrypanosomal agents

scientific article

Novel nucleoside-based antimalarial compounds

scientific article published on 23 April 2016

Optimization of chloronitrobenzamides (CNBs) as therapeutic leads for human African trypanosomiasis (HAT).

scientific article published on 26 March 2013

Optimization of purine-nitrile TbcatB inhibitors for use in vivo and evaluation of efficacy in murine models.

scientific article published on 8 October 2010

Optimization of the electrophile of chloronitrobenzamide leads active against Trypanosoma brucei

scientific article published on 23 May 2013

Optimization of triazine nitriles as rhodesain inhibitors: structure-activity relationships, bioisosteric imidazopyridine nitriles, and X-ray crystal structure analysis with human cathepsin L

scientific article

P-element inserts in transgenic flies: a cautionary tale

scientific article published in January 1997

P-element inserts in transgenic flies: a cautionary tale

PLS-Prediction and Confirmation of Hydrojuglone Glucoside as the Antitrypanosomal Constituent of Juglans Spp.

scientific article

Palladium-catalysed synthesis of arylnaphthoquinones as antiprotozoal and antimycobacterial agents

scientific article published on 12 September 2020

Parallel synthesis and antileishmanial activity of ether-linked phospholipids

scientific article published on 10 July 2008

Parallel synthesis of a series of non-functional ATP/NAD analogs with activity against trypanosomatid parasites.

scientific article published on 30 May 2009

Pentafluorosulfanyl as a novel building block for enzyme inhibitors: trypanothione reductase inhibition and antiprotozoal activities of diarylamines

scientific article

Peroxide bond-dependent antiplasmodial specificity of artemisinin and OZ277 (RBx11160).

scientific article published on 11 June 2007

Pharmacological effects of primaquine ureas and semicarbazides on the central nervous system in mice and antimalarial activity in vitro.

scientific article published on 26 October 2015

Phototemtide A, a Cyclic Lipopeptide Heterologously Expressed from Photorhabdus temperata Meg1, Shows Selective Antiprotozoal Activity

scientific article published on 09 December 2019

Phytochemical Study and Antiprotozoal Activity of Compounds Isolated fromThalia geniculata

Phytochemical Study of Salvia leriifolia Roots: Rearranged Abietane Diterpenoids with Antiprotozoal Activity

scientific article published on 13 June 2018

Potent and selective antiplasmodial activity of the cyanobacterial alkaloid nostocarboline and its dimers

scientific article published on 19 June 2008

Precursor-Directed Diversification of Cyclic Tetrapeptidic Pseudoxylallemycins

scientific article published on 04 October 2018

Preparation of Antimalarial Endoperoxides by a Formal [2 + 2 + 2] Cycloaddition

scientific article published on 22 October 2015

Preparation of Sesquiterpene Lactone-Loaded PLA Nanoparticles and Evaluation of Their Antitrypanosomal Activity

scientific article published on 04 June 2019

Preparation of new 1,3-dibenzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities

scientific article published on 29 October 2020

Procerenone: a Fatty Acid Triterpenoid from the Fruit Pericarp of Omphalocarpum procerum (Sapotaceae)

scientific article

Purpureone, an antileishmanial ergochrome from the endophytic fungus Purpureocillium lilacinum ⬇️

scientific article published in November 2016

Pyridine-4(1H)-one Alkaloids from Waltheria indica as Antitrypanosomatid Agents ⬇️

scientific article published on 23 October 2020

Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei.

scientific article

QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids

scientific article

Quantitative structure--antiprotozoal activity relationships of sesquiterpene lactones

scientific article published on 8 June 2009

Quinolone Amides as Antitrypanosomal Lead Compounds with In Vivo Activity

scientific article published on 02 May 2016

Quinuclidine derivatives as potential antiparasitics

scientific article

Rapid One-Pot Synthesis of Antiparasitic Quinolines Based upon the Microwave-Assisted Coupling-Isomerization Reaction (MACIR)

Renaissance remedies: Antiplasmodial protostane triterpenoids from Alisma plantago-aquatica L. (Alismataceae)

scientific article published on 24 February 2011

Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors

scientific article published on 13 April 2018

Repurposing of the Open Access Malaria Box for Kinetoplastid Diseases Identifies Novel Active Scaffolds against Trypanosomatids

scientific article

Rhabdopeptide/Xenortide-like Peptides from Xenorhabdus innexi with Terminal Amines Showing Potent Antiprotozoal Activity

scientific article published on 10 August 2018

Rhabdopeptides as insect-specific virulence factors from entomopathogenic bacteria

scientific article

SAR studies on azasterols as potential anti-trypanosomal and anti-leishmanial agents

scientific article published on 3 July 2009

SARs of the antiprotozoal action of 6,7-diaryl-bicyclo[2.2.2]octan-2-ols

article

SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis

scientific article

Screening and HPLC-Based Activity Profiling for New Antiprotozoal Leads from European Plants

scientific article

Search for Antiprotozoal Activity in Herbal Medicinal Preparations; New Natural Leads against Neglected Tropical Diseases.

scientific article published on 4 August 2015

Sesquiterpene Lactones from Vernonia cinerascens Sch. Bip. and Their in Vitro Antitrypanosomal Activity

scientific article

Simple "on-demand" production of bioactive natural products

scientific article

Steroid Alkaloids from Holarrhena africana with Strong Activity against Trypanosoma brucei rhodesiense.

scientific article

Structural Requirements for the Antiprotozoal Activity of 4-Aminobicyclo[2.2.2]octan-2-ols

article

Structural and thermodynamic basis of the inhibition ofLeishmania majorfarnesyl diphosphate synthase by nitrogen-containing bisphosphonates

scientific article

Structure Elucidation and Activity of Kolossin A, the D-/L-Pentadecapeptide Product of a Giant Nonribosomal Peptide Synthetase

scientific article

Structure and Biosynthesis of Isatropolones, Bioactive Amine-Scavenging Fluorescent Natural Products from Streptomyces Gö66.

scientific article published on 30 March 2017

Structure and biosynthesis of xenoamicins from entomopathogenic Xenorhabdus. ⬇️

scientific article published on 7 November 2013

Structure determination of the bioactive depsipeptide xenobactin from Xenorhabdus sp. PB30.3

scholarly article in RSC Advances, vol. 3 no. 44, 2013

Structure, Biosynthesis, and Bioactivity of Photoditritide from Photorhabdus temperata Meg1

scientific article published on 04 December 2019

Structure-Activity Relationship in Pyrazolo[4,3-c]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity

scientific article published on 06 January 2020

Structure-Activity Relationships of Cinnamate Ester Analogues as Potent Antiprotozoal Agents

scientific article published on 12 November 2019

Structure-activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues

scientific article published on 3 September 2009

Structure-activity relationship studies of pyrrolone antimalarial agents

scientific article published on 05 August 2013

Structure-activity relationship studies on thiaplidiaquinones A and B as novel inhibitors of Plasmodium falciparum and farnesyltransferase

scientific article published on 19 June 2017

Structure-activity relationship study of sesquiterpene lactones and their semi-synthetic amino derivatives as potential antitrypanosomal products.

scientific article published on 21 March 2014

Substituted flavones: a promising scaffold in the fight against malaria.

scientific article published on 22 September 2014

Synthesis and Antimalarial Activity of Some Neocryptolepine Analogues Carrying a Multifunctional Linear and Branched Carbon-Side Chains

Synthesis and Biological Properties of a Rhodacyanine Derivatives, SSJ-127, Having High Efficacy against Malaria Protozoa

scholarly article by Masataka Ihara et al published 2009 in Heterocycles

Synthesis and Evaluation of the Antitrypanosomal and Antiplasmodial Activities of New 4-Aminobicyclo[2.2.2]octane Derivatives

article

Synthesis and activity of nucleoside-based antiprotozoan compounds.

scientific article published on 16 February 2017

Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3]triazoles

scientific article published on 27 December 2011

Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers

scientific article

Synthesis and antimalarial efficacy of aza-fused rhodacyanines in vitro and in the P. berghei mouse model

scientific article published on July 2006

Synthesis and antimalarial evaluation of artesunate-polyamine and trioxolane-polyamine conjugates.

scientific article published on 22 September 2017

Synthesis and antimalarial property of orally active phenoxazinium salts.

scientific article published on 19 April 2007

Synthesis and antimalarial testing of neocryptolepine analogues: addition of ester function in SAR study of 2,11-disubstituted indolo[2,3-b]quinolines.

scientific article published on 15 April 2013

Synthesis and antiplasmodial activity of new N-[3-(4-{3-[(7-chloroquinolin-4-yl)amino]propyl}piperazin-1-yl)propyl]carboxamides

scientific article published on 24 December 2006

Synthesis and antiprotozoal activities of new 3-azabicyclo[3.2.2]nonanes

scientific article published on 30 November 2014

Synthesis and antiprotozoal activities of simplified analogs of naphthylisoquinoline alkaloids

scientific article

Synthesis and antiprotozoal activity of N-alkoxy analogues of the trypanocidal lead compound 4,4'-bis(imidazolinylamino)diphenylamine with improved human blood-brain barrier permeability

scientific article published on 22 December 2010

Synthesis and biological evaluation of phosphate prodrugs of 4-phospho-D-erythronohydroxamic acid, an inhibitor of 6-phosphogluconate dehydrogenase

scientific article

Synthesis and biological investigation of (+)-3-hydroxymethylartemisinin

scientific article published on 27 February 2019

Synthesis and evaluation of 2-pyridyl pyrimidines with in vitro antiplasmodial and antileishmanial activity

scientific article

Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives

scientific article published on 20 October 2007

Synthesis and evaluation of artesunate–indoloquinoline hybrids as antimalarial drug candidates

Synthesis and evaluation of phenoxymethylbenzamide analogues as anti-trypanosomal agents

Synthesis and evaluation of the antitrypanosomal and antiplasmodial activities of new 4-aminobicyclo[2.2.2]octane derivatives

scientific article

Synthesis and in vitro and in vivo evaluation of antimalarial polyamines

scientific article

Synthesis and in vitro antimalarial testing of neocryptolepines: SAR study for improved activity by introduction and modifications of side chains at C2 and C11 on indolo[2,3-b]quinolines

scientific article published on 15 February 2013

Synthesis and in vitro antiprotozoal activities of 5-phenyliminobenzo[a]phenoxazine derivatives

scientific article published on 5 August 2011

Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive 3,7-bis(dialkylamino)phenoxazin-5-ium derivatives

scientific article published on 14 May 2008

Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive phenothiazinium chlorides

Synthesis and in vitro testing of antimalarial activity of non-natural-type neocryptolepines: structure–activity relationship study of 2,11- and 9,11-disubstituted 6-methylindolo[2,3-b]quinolines.

scientific article published on January 2013

Synthesis and potent antiprotozoal activity of mono/di amidino 2-anilinobenzimidazoles versus Plasmodium falciparum and Trypanosoma brucei rhodesiense.

scientific article published on 25 June 2016

Synthesis and structure-activity analysis of new phosphonium salts with potent activity against African trypanosomes.

scientific article

Synthesis and structure-activity relationships for new 6-fluoroquinoline derivatives with antiplasmodial activity

scientific article published on 02 April 2019

Synthesis and structure-activity relationships of new quinolone-type molecules against Trypanosoma brucei

scientific article

Synthesis of 2-azabicyclo[3.2.2]nonanes from bicyclo[2.2.2]octan-2-ones and their activities against Trypanosoma brucei rhodesiense and Plasmodium falciparum K1.

scientific article published on 28 October 2005

Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities

scientific article

Synthesis of Jacaranone-Derived Nitrogenous Cyclohexadienones and Their Antiproliferative and Antiprotozoal Activities

scientific article published on 07 November 2018

Synthesis of Novel Diazabicycles and their Antiprotozoal Activities

article

Synthesis of a potent antimalarial agent through natural products conjugation

scientific article published on 10 January 2013

Synthesis of a series of N6-substituted adenosines with activity against trypanosomatid parasites

scientific article published on 20 February 2009

Synthesis of antiprotozoal diamines by regioselective insertion of nitrogen into a bicyclic ring system

article

Synthesis of bicyclic amines and their activities against Trypanosoma brucei rhodesiense and Plasmodium falciparum K1.

scientific article published on 19 June 2008

Synthesis of cyanine dyes and investigation of their in vitro antiprotozoal activities

Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities

scientific article published on 10 November 2017

Synthesis of new esters and oximes with 4-aminobicyclo[2.2.2]octane structure and evaluation of their antitrypanosomal and antiplasmodial activities

scientific article published on 26 May 2006

Synthesis of new tetrahydropyridinylidene ammonium salts and their antiprotozoal potency

Synthesis of szentiamide, a depsipeptide from entomopathogenic Xenorhabdus szentirmaii with activity against Plasmodium falciparum

scientific article published on 11 April 2012

Synthesis of three classes of rhodacyanine dyes and evaluation of their in vitro and in vivo antimalarial activity

scientific article published on 12 September 2006

Synthesis, biological evaluation, and structure-activity relationships of N-benzoyl-2-hydroxybenzamides as agents active against P. falciparum (K1 strain), Trypanosomes, and Leishmania

scientific article

Synthesis, crystal structure, and in vitro antiprotozoal activity of some 5-phenyl(methyl)sulfonyl-substituted dihydroisoxazoles

Synthesis, in-vitro antiprotozoal activity and molecular docking study of isothiocyanate derivatives

scientific article published on 09 November 2019

Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on mepacrine-conjugated diaryl sulfide scaffolds

scientific article published in December 2009

Synthesis, β-haematin inhibition, and in vitro antimalarial testing of isocryptolepine analogues: SAR study of indolo[3,2-c]quinolines with various substituents at C2, C6, and N11.

scientific article published on 26 March 2014

Targeting a Large Active Site: Structure-Based Design of Nanomolar Inhibitors of Trypanosoma brucei Trypanothione Reductase

scientific article published on 13 August 2019

Targeting the parasite's DNA with methyltriazenyl purine analogs is a safe, selective, and efficacious antitrypanosomal strategy

scientific article

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

scientific article published on 13 July 2020

Terpenoids from the Oleo-Gum-Resin of Boswellia serrata and Their Antiplasmodial Effects In Vitro.

scientific article published on 24 July 2017

The Antimalarial Activity of Artemisinin is not Stereospecific.

scientific article published on 3 May 2018

The antiprotozoal activity of methylated flavonoids from Ageratum conyzoides L.

scientific article published on 26 February 2010

The antiprotozoal activity of sixteen asteraceae species native to Sudan and bioactivity-guided isolation of xanthanolides from Xanthium brasilicum.

scientific article published on 8 May 2009

The antiprotozoal potencies of newly prepared 3-azabicyclo[3.2.2]nonanes

scientific article

The antitrypanosomal and antitubercular activity of some nitro(triazole/imidazole)-based aromatic amines.

scientific article

The discovery of novel antitrypanosomal 4-phenyl-6-(pyridin-3-yl)pyrimidines

scientific article published on 05 October 2020

The effects of enhanced expression of elongation factor EF-1 alpha on lifespan in Drosophila melanogaster. IV. A summary of three experiments

scientific article published on January 1993

The effects of enhanced expression of elongation factor EF-1α on lifespan in Drosophila melanogaster

The production and antiprotozoal activity of abietane diterpenes in Salvia austriaca hairy roots grown in shake flasks and bioreactor.

scientific article published on 12 April 2016

Toward the development of dual-targeted glyceraldehyde-3-phosphate dehydrogenase/trypanothione reductase inhibitors against Trypanosoma brucei and Trypanosoma cruzi.

scientific article

Trypanocidal activity of diarylheptanoids from Schrankia leptocarpa DC

scientific article published in 2012

Trypanocidal, leishmanicidal and cytotoxic effects of anthecotulide-type linear sesquiterpene lactones from Anthemis auriculata

scientific article

Trypanosoma cruzi STIB980: A TcI Strain for Drug Discovery and Reverse Genetics

scientific article published on 4 October 2023

Trypanothione reductase high-throughput screening campaign identifies novel classes of inhibitors with antiparasitic activity

scientific article published on 13 April 2009

Validation of Plasmodium falciparum dUTPase as the target of 5'-tritylated deoxyuridine analogues with anti-malarial activity

scientific article published on 03 December 2019

Wayanin and guaijaverin, two active metabolites found in a Psidium acutangulum Mart. ex DC (syn. P. persoonii McVaugh) (Myrtaceae) antimalarial decoction from the Wayana Amerindians.

scientific article

Xenortide Biosynthesis by Entomopathogenic Xenorhabdus nematophila

scientific article

ent-Pimarane and ent-Kaurane Diterpenes from Aldama discolor (Asteraceae) and Their Antiprotozoal Activity.

scientific article published on 15 September 2016

β-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase

scientific article

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