List of works by David J. Conway

A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains

scientific article

A decline in the incidence of invasive non-typhoidal Salmonella infection in The Gambia temporally associated with a decline in malaria infection

scientific article

A heat-shock response regulated by the PfAP2-HS transcription factor protects human malaria parasites from febrile temperatures

scientific article published on 16 August 2021

A large focus of naturally acquired Plasmodium knowlesi infections in human beings

scientific article

A malaria parasite subtilisin propeptide-like protein is a potent inhibitor of the egress protease SUB1.

scientific article published on 01 January 2020

A polyvalent hybrid protein elicits antibodies against the diverse allelic types of block 2 in Plasmodium falciparum merozoite surface protein 1.

scientific article published on 04 August 2011

A principal target of human immunity to malaria identified by molecular population genetic and immunological analyses

scientific article published on June 2000

A randomised trial to compare the safety, tolerability and efficacy of three drug combinations for intermittent preventive treatment in children

scientific article

Acquisition of antibody isotypes against Plasmodium falciparum blood stage antigens in a birth cohort

scientific article

Admixture in Humans of Two Divergent Plasmodium knowlesi Populations Associated with Different Macaque Host Species

scientific article published on 28 May 2015

Allele Frequency-Based Analyses Robustly Map Sequence Sites Under Balancing Selection in a Malaria Vaccine Candidate Antigen ⬇️

scientific article published on October 1, 2003

Allele frequency-based and polymorphism-versus-divergence indices of balancing selection in a new filtered set of polymorphic genes in Plasmodium falciparum

scientific article

Allele-specific antibodies to Plasmodium falciparum merozoite surface protein-2 and protection against clinical malaria.

scientific article

Allelic diversity and naturally acquired allele-specific antibody responses to Plasmodium falciparum apical membrane antigen 1 in Kenya

scientific article

Allelic lineages of the merozoite surface protein 3 gene in Plasmodium reichenowi and Plasmodium falciparum

scientific article

Allelic recombination and linkage disequilibrium within Msp-1 of Plasmodium falciparum, the malignant human malaria parasite

scientific article published in April 1999

An expanded global inventory of allelic variation in the most extremely polymorphic region of Plasmodium falciparum merozoite surface protein 1 provided by short read sequence data

scientific article

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

scientific article published on 24 February 2021

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

scientific article (publication date: 19 July 2012)

Analysis of antibodies to newly described Plasmodium falciparum merozoite antigens supports MSPDBL2 as a predicted target of naturally acquired immunity

scientific article published on 29 July 2013

Analysis of erythrocyte invasion mechanisms of plasmodium falciparum clinical isolates across 3 malaria-endemic areas in Ghana ⬇️

scientific article

Analysis of human antibodies to erythrocyte binding antigen 175 of Plasmodium falciparum

scientific article

Anopheles gambiae complex along The Gambia river, with particular reference to the molecular forms of An. gambiae s.s.

scientific article published on 22 September 2008

Antibodies to the N-terminal block 2 of plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malaria ⬇️

scientific article published in November 2004

Antibody Reactivity to Merozoite Antigens in Ghanaian Adults Correlates With Growth Inhibitory Activity Against Plasmodium falciparum in Culture

scientific article published on 28 May 2019

Assessing the impact of differences in malaria transmission intensity on clinical and haematological indices in children with malaria

scientific article published on March 2017

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

scientific article

Boosting antibody responses to Plasmodium falciparum merozoite antigens in children with highly seasonal exposure to infection

scientific article

Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malaria

scientific article published on 3 March 2008

Breakdown in the process of incipient speciation in Anopheles gambiae

scientific article published on 18 January 2013

Case-control approach to identify Plasmodium falciparum polymorphisms associated with severe malaria

scientific article

Changes in malaria indices between 1999 and 2007 in The Gambia: a retrospective analysis

scientific article

Changes in malaria parasite drug resistance in an endemic population over a 25-year period with resulting genomic evidence of selection

scientific article

Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia

scientific article published on 09 January 2017

Characterizing the genetic diversity of the monkey malaria parasite Plasmodium cynomolgi

scientific article published on 12 March 2016

Clinical features of severe malaria associated with death: a 13-year observational study in the Gambia

scientific article

Comparative analysis of Plasmodium reichenowi and P. falciparum erythrocyte-binding proteins reveals selection to maintain polymorphism in the erythrocyte-binding region of EBA-175.

scientific article published in August 2001

Comparison of genomic signatures of selection on Plasmodium falciparum between different regions of a country with high malaria endemicity

scientific article published on 16 July 2015

Comparison of surveillance methods applied to a situation of low malaria prevalence at rural sites in The Gambia and Guinea Bissau

scientific article published on 02 December 2009

Complement Factor H Levels Associate With Malaria Susceptibility and Severity

scholarly article by Anna E van Beek et al published July 2018 in Open Forum Infectious Diseases

Consistent signatures of selection from genomic analysis of pairs of temporal and spatial Plasmodium falciparum populations from The Gambia.

scientific article

Continued decline of malaria in The Gambia with implications for elimination

scientific article

Contrasting signatures of selection on the Plasmodium falciparum erythrocyte binding antigen gene family

scientific article published on 22 June 2006

Correction: Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations.

scientific article published on 27 June 2013

Cross-sectional study of specific antibodies to a polymorphic Plasmodium falciparum antigen and of parasite antigen genotypes in school children on the slope of Mount Cameroon

scientific article

Culture adaptation of malaria parasites selects for convergent loss-of-function mutants

scientific article published on 24 January 2017

Detecting signatures of balancing selection to identify targets of anti-parasite immunity

scientific article published on 11 May 2010

Differential evidence of natural selection on two leading sporozoite stage malaria vaccine candidate antigens

scientific article published on 25 September 2006

Distinct roles for FOXP3 and FOXP3 CD4 T cells in regulating cellular immunity to uncomplicated and severe Plasmodium falciparum malaria

scientific article

Dry season ecology of Anopheles gambiae complex mosquitoes in The Gambia

scientific article published on 18 August 2008

Duration of naturally acquired antibody responses to blood-stage Plasmodium falciparum is age dependent and antigen specific

scientific article published on 22 January 2008

Dynamics of the antibody response to Plasmodium falciparum infection in African children

scientific article published on 8 April 2014

Effect of two different house screening interventions on exposure to malaria vectors and on anaemia in children in The Gambia: a randomised controlled trial

scientific article published on 03 September 2009

Effects of genetic variation at the CYP2C19/CYP2C9 locus on pharmacokinetics of chlorcycloguanil in adult Gambians

scientific article published on September 2009

Efficacy of RTS,S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial

scientific article published in December 2001

Efficacy of indoor residual spraying with dichlorodiphenyltrichloroethane against malaria in Gambian communities with high usage of long-lasting insecticidal mosquito nets: a cluster-randomised controlled trial

scientific article published on 9 December 2014

Efficient Surveillance of Plasmodium knowlesi Genetic Subpopulations, Malaysian Borneo, 2000-2018

scientific article published on 01 July 2020

Enzyme polymorphisms in Ascaris lumbricoides in Bangladesh

scientific article

Epigenetic dysregulation of virulence gene expression in severe Plasmodium falciparum malaria

scientific article

Erratum to: Cross-sectional study of specific antibodies to a polymorphic Plasmodium falciparum antigen and of parasite antigen genotypes in school children on the slope of Mount Cameroon

scholarly article by Helen K. Kimbi et al published December 2004 in Transactions of the Royal Society of Tropical Medicine and Hygiene

Erythrocyte invasion and merozoite ligand gene expression in severe and mild Plasmodium falciparum malaria

scientific article published on February 2010

Erythrocyte invasion phenotypes of Plasmodium falciparum in The Gambia ⬇️

scientific article

Estimating parasite load dynamics to reveal novel resistance mechanisms to human malaria

article

Evidence for diversifying selection on erythrocyte-binding antigens of Plasmodium falciparum and P. vivax

scientific article

Evidence of non-neutral polymorphism in Plasmodium falciparum gamete surface protein genes Pfs47 and Pfs48/45.

scientific article published on 20 July 2007

Exceptionally long-range haplotypes in Plasmodium falciparum chromosome 6 maintained in an endemic African population

scientific article published on 21 October 2016

Expression of Plasmodium falciparum genes involved in erythrocyte invasion varies among isolates cultured directly from patients ⬇️

scientific article

Extensive antigenic polymorphism within the repeat sequence of the Plasmodium falciparum merozoite surface protein 1 block 2 is incorporated in a minimal polyvalent immunogen

scientific article published on September 2005

Extreme geographical fixation of variation in the Plasmodium falciparum gamete surface protein gene Pfs48/45 compared with microsatellite loci

scientific article published on July 2001

Factors affecting the efficacy of ivermectin against Heligmosomoides polygyrus (Nematospiroides dubius) in mice

scientific article published on August 1989

Field testing of different chemical combinations as odour baits for trapping wild mosquitoes in The Gambia

scientific article

Fragmented population structure of plasmodium falciparum in a region of declining endemicity.

scientific article published on 25 March 2005

Gene copy number variation throughout the Plasmodium falciparum genome

scientific article

Gene polymorphism of Plasmodium falciparum merozoite surface proteins 4 and 5.

scientific article published in July 2005

Gene-specific signatures of elevated non-synonymous substitution rates correlate poorly across the Plasmodium genus

scientific article

Genetic evidence for the importance of interrupted feeding by mosquitoes in the transmission of malaria

scientific article published in July 1991

Genetic structure of Plasmodium falciparum populations in the Brazilian Amazon region

scientific article published on 21 September 2004

Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts.

scientific article

Genome-wide analysis of selection on the malaria parasite Plasmodium falciparum in West African populations of differing infection endemicity

scientific article

Genome-wide and fine-resolution association analysis of malaria in West Africa

scientific article

Genome-wide mosaicism in divergence between zoonotic malaria parasite subpopulations with separate sympatric transmission cycles

scientific article published on 2 January 2018

Genomic epidemiology of the current wave of artemisinin resistant malaria

scholarly article by Roberto Amato et al published 22 May 2015 in bioRxiv

Genotyping of Plasmodium falciparum infections by PCR: a comparative multicentre study

scientific article

Geographical distribution of a variant epitope of Pfs48/45, a Plasmodium falciparum transmission-blocking vaccine candidate

scientific article

HMOX1 gene promoter alleles and high HO-1 levels are associated with severe malaria in Gambian children

scientific article

Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria

scientific article

Health centre surveys as a potential tool for monitoring malaria epidemiology by area and over time

scientific article

Heritability of antibody isotype and subclass responses to Plasmodium falciparum antigens

scientific article

High levels of serum antibodies to merozoite surface protein 2 of Plasmodium falciparum are associated with reduced risk of clinical malaria in coastal Kenya

scientific article

High recombination rate in natural populations of Plasmodium falciparum

scientific article

High-throughput sequence typing of T-cell epitope polymorphisms in Plasmodium falciparum circumsporozoite protein

scientific article published on March 2000

Homeostatic regulation of T effector to Treg ratios in an area of seasonal malaria transmission

scientific article

Household aggregation of Strongyloides stercoralis infection in Bangladesh

scientific article

Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria ⬇️

scientific article

Human antibodies to recombinant protein constructs of Plasmodium falciparum Apical Membrane Antigen 1 (AMA1) and their associations with protection from malaria

scientific article

Human saliva as a source of anti-malarial antibodies to examine population exposure to Plasmodium falciparum

scientific article

Humoral responses in human strongyloidiasis: correlations with infection chronicity

article

IgG antibody responses to Plasmodium falciparum merozoite antigens in Kenyan children have a short half-life

scientific article published on 28 June 2007

Immunodiagnosis of Strongyloides stercoralis infection: a method for increasing the specificity of the indirect Elisa

scientific article published on 01 March 1993

Improving malaria control in West Africa: interruption of transmission as a paradigm shift

scientific article published on 28 November 2011

Imputation-based meta-analysis of severe malaria in three African populations

scientific article

In the blood--the remarkable ancestry of Plasmodium falciparum

scientific article published on August 2002

Induction of strain-transcending antibodies against Group A PfEMP1 surface antigens from virulent malaria parasites

scientific article

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

scientific article published in June 2018

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

scholarly article published 25 September 2017

Intrinsic multiplication rate variation and plasticity of human blood stage malaria parasites

scientific article published on 28 October 2020

Invasion pathways and malaria severity in Kenyan Plasmodium falciparum clinical isolates ⬇️

scientific article published on 16 April 2007

Investigating a Plasmodium falciparum erythrocyte invasion phenotype switch at the whole transcriptome level ⬇️

scientific article published on 14 January 2020

Is mosquito larval source management appropriate for reducing malaria in areas of extensive flooding in The Gambia? A cross-over intervention trial

scientific article

Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development ⬇️

scientific article

KILchip v1.0: A Novel Merozoite Protein Microarray to Facilitate Malaria Vaccine Candidate Prioritization

scientific article published on 11 December 2018

Killer-cell immunoglobulin-like receptors and falciparum malaria in southwest Nigeria

scientific article published on 11 June 2014

Killer-cell immunoglobulin-like receptors and malaria caused by Plasmodium falciparum in The Gambia.

scientific article published in February 2012

L3 antigen-specific antibody isotype responses in human strongyloidiasis: correlations with larval output

article

Long read assemblies of geographically dispersed isolates reveal highly structured subtelomeres

article

Malaria Vaccine Development: Focusing Field Erythrocyte Invasion Studies on Phenotypic Diversity: The West African Merozoite Invasion Network (WAMIN).

scientific article published on 22 December 2015

Malaria protection due to sickle haemoglobin depends on parasite genotype

scientific article published in February 2022

Microsatellite genotyping and genome-wide single nucleotide polymorphism-based indices of Plasmodium falciparum diversity within clinical infections

scientific article published on 12 May 2016

Modelling pathogen load dynamics to elucidate mechanistic determinants of host-Plasmodium falciparum interactions

scientific article published on 17 June 2019

Molecular characterisation of Plasmodium reichenowi apical membrane antigen-1 (AMA-1), comparison with P. falciparum AMA-1, and antibody-mediated inhibition of red cell invasion.

scientific article published on July 2000

Molecular epidemiology of malaria

scientific article published on January 2007

Multi-locus genotyping reveals established endemicity of a geographically distinct Plasmodium vivax population in Mauritania, West Africa

scientific article published on 16 December 2020

Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development

scientific article published in Scientific Reports

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

scientific article published on 28 April 2013

Multiplication rate variation in the human malaria parasite Plasmodium falciparum

scientific article published on 25 July 2017

Natural selection on polymorphic malaria antigens and the search for a vaccine

scientific article published on January 1997

Natural selection on the erythrocyte surface

scientific article

Naturally acquired antibodies to polymorphic and conserved epitopes of Plasmodium falciparum merozoite surface protein 3.

scientific article

Optimizing odor-baited trap methods for collecting mosquitoes during the malaria season in The Gambia

scientific article

Oral activated charcoal prevents experimental cerebral malaria in mice and in a randomized controlled clinical trial in man did not interfere with the pharmacokinetics of parenteral artesunate

scientific article

Origin of Plasmodium falciparum malaria is traced by mitochondrial DNA.

scientific article published on November 2000

Orthologous gene sequences of merozoite surface protein 1 (MSP1) from Plasmodium reichenowi and P. gallinaceum confirm an ancient divergence of P. falciparum alleles

scientific article

PCR-based karyotyping of Anopheles gambiae inversion 2Rj identifies the BAMAKO chromosomal form

scientific article

Paths to a malaria vaccine illuminated by parasite genomics

scientific article

PfHPRT: a new biomarker candidate of acute Plasmodium falciparum infection

scientific article published on 12 February 2013

PlasmoView: a web-based resource to visualise global Plasmodium falciparum genomic variation

scientific article

Plasmodium Infection Is Associated with Impaired Hepatic Dimethylarginine Dimethylaminohydrolase Activity and Disruption of Nitric Oxide Synthase Inhibitor/Substrate Homeostasis

scientific article

Plasmodium falciparum Merozoite Associated Armadillo Protein (PfMAAP) Is Apically Localized in Free Merozoites and Antibodies Are Associated With Reduced Risk of Malaria

scientific article published on 07 April 2020

Plasmodium falciparum merozoite surface protein 3 is a target of allele-specific immunity and alleles are maintained by natural selection

scientific article

Plasmodium falciparum schizont stage transcriptome variation among clinical isolates and laboratory-adapted clones

Plasmodium falciparum: intragenic recombination and nonrandom associations between polymorphic domains of the precursor to the major merozoite surface antigens

scientific article published on November 1991

Plasmodium knowlesi malaria in humans is widely distributed and potentially life threatening

scientific article

Plasmodium knowlesi: reservoir hosts and tracking the emergence in humans and macaques

scientific article published in April 2011

Polymorphisms in candidate genes and risk of scarring trachoma in a Chlamydia trachomatis--endemic population.

scientific article published on 09 October 2000

Polymorphisms in erythrocyte binding antigens 140 and 181 affect function and binding but not receptor specificity in Plasmodium falciparum

scientific article published on 09 February 2009

Polymorphisms in the IkappaB-alpha promoter region and risk of diseases involving inflammation and fibrosis

scientific article

Polymorphisms in the tumor necrosis factor-alpha gene promoter may predispose to severe silicosis in black South African miners.

scientific article published in March 2002

Population Genomic Structure and Recent Evolution of Plasmodium knowlesi, Peninsular Malaysia

scientific article published on 01 August 2020

Population Structure Shapes Copy Number Variation in Malaria Parasites

scientific article published on 26 November 2015

Population genetic analysis of the Plasmodium falciparum erythrocyte binding antigen-175 (eba-175) gene

scientific article

Population genetic structure and adaptation of malaria parasites on the edge of endemic distribution.

scientific article

Population genetic structure of Plasmodium falciparum across a region of diverse endemicity in West Africa

scientific article

Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites

scientific article

Population genomic structure and adaptation in the zoonotic malaria parasite Plasmodium knowlesi

scientific article

Prescribing practice for malaria following introduction of artemether-lumefantrine in an urban area with declining endemicity in West Africa.

scientific article

Prevention of the recurrence of anaemia in Gambian children following discharge from hospital

scientific article

Profiling the antibody immune response against blood stage malaria vaccine candidates

scientific article published on 17 May 2007

Prominent intraspecific genetic divergence within Anopheles gambiae sibling species triggered by habitat discontinuities across a riverine landscape

scientific article

Prospective identification of malaria parasite genes under balancing selection

scientific article published on 15 May 2009

Protective efficacy of the RTS,S/AS02 Plasmodium falciparum malaria vaccine is not strain specific

scientific article published on January 2003

Quantitative detection of Plasmodium falciparum DNA in saliva, blood, and urine

scientific article published in June 2009

RTS,S/AS02A malaria vaccine does not induce parasite CSP T cell epitope selection and reduces multiplicity of infection

scientific article

Randomized trial of safety and effectiveness of chlorproguanil-dapsone and lumefantrine-artemether for uncomplicated malaria in children in the Gambia

scientific article

Remarkable diversity of intron-1 of the para voltage-gated sodium channel gene in an Anopheles gambiae/Anopheles coluzzii hybrid zone

scientific article published on 21 January 2015

Repeat sequences in block 2 of Plasmodium falciparum merozoite surface protein 1 are targets of antibodies associated with protection from malaria

scientific article published in April 2003

Resistance to malaria through structural variation of red blood cell invasion receptors

scientific article published on 18 May 2017

Resistance to malaria through structural variation of red blood cell invasion receptors

scholarly article published 26 October 2016

Risk factors for house-entry by malaria vectors in a rural town and satellite villages in The Gambia

scientific article

SNP genotyping identifies new signatures of selection in a deep sample of West African Plasmodium falciparum malaria parasites

scientific article published on 11 June 2012

Sahel, savana, riverine and urban malaria in West Africa: Similar control policies with different outcomes

scientific article published on 19 November 2011

Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of the malaria parasite Plasmodium falciparum

scientific article published on 10 December 2018

Seroepidemiological and parasitological evaluation of the heterogeneity of malaria infection in the Gambia

scientific article published on July 2013

Serology describes a profile of declining malaria transmission in Farafenni, The Gambia

scientific article

Serum IgG3 to the Plasmodium falciparum merozoite surface protein 2 is strongly associated with a reduced prospective risk of malaria

scientific article published in June 2003

Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture.

scholarly article

Strongyloides stercoralis in an urban slum community in Bangladesh: factors independently associated with infection.

scientific article

Strongyloides stercoralis: characterization of immunodiagnostic larval antigens

scientific article published in September 1994

Study protocol for a three-armed randomized controlled trial to assess whether house screening can reduce exposure to malaria vectors and reduce malaria transmission in The Gambia

scientific article published on 6 June 2008

The "far-west" of Anopheles gambiae molecular forms.

scientific article

The Gini coefficient as a useful measure of malaria inequality among populations

scientific article published on 02 December 2020

The breadth, but not the magnitude, of circulating memory B cell responses to P. falciparum increases with age/exposure in an area of low transmission

scientific article

The major allelic dimorphisms in four Plasmodium falciparum merozoite proteins are not associated with alternative pathways of erythrocyte invasion

scientific article

Three Divergent Subpopulations of the Malaria Parasite Plasmodium knowlesi

scientific article published on April 2017

To assess whether indoor residual spraying can provide additional protection against clinical malaria over current best practice of long-lasting insecticidal mosquito nets in The Gambia: study protocol for a two-armed cluster-randomised trial

scientific article

Tracing the dawn of Plasmodium falciparum with mitochondrial genome sequences

scientific article published on December 2003

Transcriptomic Studies of Malaria: a Paradigm for Investigation of Systemic Host-Pathogen Interactions

scholarly article by Hyun Jae Lee et al published 1 June 2018 in Microbiology and Molecular Biology Reviews

Two strategies for the delivery of IPTc in an area of seasonal malaria transmission in the Gambia: a randomised controlled trial

scientific article

Variation in Plasmodium falciparum erythrocyte invasion phenotypes and merozoite ligand gene expression across different populations in areas of malaria endemicity ⬇️

scientific article published on 13 April 2015

Widespread distribution of Plasmodium vivax malaria in Mauritania on the interface of the Maghreb and West Africa

scientific article published on 9 February 2016

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