List of works - Richard Furneaux

(1R,2R,3S,5R,6R,7S,9aR,10aR)-4a,8a-Diazaperhydroanthracene-1,2,3,5,6,7-hexaol

1,3-Dideoxynojirimycin-3-yl glycosides of beta-(1-->3)- and beta-(1-->6)-linked gluco-oligosaccharides

scientific article published on 05 June 2006

1-Deoxy-D-galactonojirimycins with dansyl capped N-substituents as β-galactosidase inhibitors and potential probes for GM1 gangliosidosis affected cell lines.

scientific article published on 24 May 2011

1-Deoxynojirimycins with dansyl capped N-substituents as probes for Morbus Gaucher affected cell lines

scientific article

8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases

scientific article

A fluorescent probe for GM1 gangliosidosis related β-galactosidase: N-(dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino-D-galactitol

scientific article published on 10 September 2011

A novel and simple colorimetric method for screening Giardia intestinalis and anti-giardial activity in vitro

scientific article published on 01 September 1998

A novel mechanism for desulfation of mucin: identification and cloning of a mucin-desulfating glycosidase (sulfoglycosidase) from Prevotella strain RS2

scientific article

A novel phosphatidylinositol manno-oligosaccharide (dPIM-8) from Gordonia sputi

scientific article published in July 2005

A practical synthesis of (3R,4R)-N-tert-butoxycarbonyl-4-hydroxymethylpyrrolidin-3-ol

scientific article published on 20 July 2007

A procedure for the analysis of glycosaminoglycan mixtures based on digestion by specific enzymes

scientific article published on 01 March 1994

A simple synthesis of 8-(methoxycarbonyl)octyl 3,6-di-O-(alpha-D-mannopyranosyl)-alpha-D-mannopyranoside and derivatives and their use in the preparation of neoglycoconjugates

scientific article published on 01 January 1999

A synchrotron radiation study of the one-dimensional complex of sodium with (1S)-N-carboxylato-1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol, a member of the 'immucillin' family

scientific article

Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase

scientific article published on 3 July 2003

Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: convergent synthesis of the aza-C-nucleoside immucillins.

scientific article published in August 2001

Alkyl 4-chlorobenzoyloxycarbamates as highly effective nitrogen source reagents for the base-free, intermolecular aminohydroxylation reaction

scientific article published on 29 December 2010

Analysis of pyruvylated beta-carrageenan by 2D NMR spectroscopy and reductive partial hydrolysis

scientific article

Approaches to the Synthesis of Glycosides

1976 doctoral thesis by Richard Hubert Furneaux at Victoria University of Wellington

Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs.

scientific article

Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase

scientific article

Azetidine based transition state analogue inhibitors of N-ribosyl hydrolases and phosphorylases

scientific article published on 6 February 2008

Carrageenans from the tetrasporic stages of Gigartina clavifera and Gigartina alveata (Gigartinaceae, Rhodophyta)

scientific article published on 01 October 1995

Chemical and spectroscopic characterisation of the phosphatidylinositol manno-oligosaccharides from Mycobacterium bovis AN5 and WAg201 and Mycobacterium smegmatis mc2 155

scientific article published on 01 June 1998

Chemical methods for the analysis of sulphated galactans from red algae

scientific article published on 1 March 1991

Chemotaxonomy of New Zealand red algae in the family Gigartinaceae (Rhodophyta) based on galactan structures from the tetrasporophyte life-stage

scientific article

Corrigendum to “Synthesis and utility of sulfated chromogenic carbohydrate model substrates for measuring activities of mucin-desulfating enzymes”

scholarly article published in Carbohydrate Research

Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,)

scientific article

Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases.

scientific article published on 16 June 2005

Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.

scientific article

Femtomolar transition state analogue inhibitors of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli

scientific article published on 04 March 2005

Glucofuranosylation with penta-O-propanoyl-beta-D-glucofuranose.

scientific article published in November 2002

Imino-C-nucleoside synthesis: heteroaryl lithium carbanion additions to a carbohydrate cyclic imine and nitrone

scientific article published in March 2004

Iminoribitol Transition State Analogue Inhibitors of Protozoan Nucleoside Hydrolases†

article

Improved Syntheses of 3H,5H-Pyrrolo[3,2-d]pyrimidines

scientific article published on 01 October 1999

Inhibition and Structure of Trichomonas vaginalis Purine Nucleoside Phosphorylase with Picomolar Transition State Analogues †

scientific article

Inhibition of angiogenesis by oral ingestion of powdered shark cartilage in a rat model

scientific article published on 01 September 1997

Inhibition of ricin A-chain with pyrrolidine mimics of the oxacarbenium ion transition state.

scientific article

Inhibitors of ADP-ribosylating bacterial toxins based on oxacarbenium ion character at their transition states

scientific article

Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases

scientific article published in May 2003

Isozyme-specific transition state inhibitors for the trypanosomal nucleoside hydrolases

scientific article published on 01 March 1997

Mannosylated liposomes as antigen delivery vehicles for targeting to dendritic cells

scientific article published on 01 June 2006

One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase

scientific article

Optimization of alkyl beta-D-galactopyranoside synthesis from lactose using commercially available beta-galactosidases

scientific article published on 01 August 1993

Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase

scientific article (publication date: 27 May 2003)

Picomolar inhibitors as transition-state probes of 5'-methylthioadenosine nucleosidases

scientific article

Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A

scientific article

Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function

scientific article published on 23 February 2004

Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts

scientific article published in July 2001

Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase

scientific article published on 12 November 2001

Ricin A-chain inhibitors resembling the oxacarbenium ion transition state

scientific article

Robert John (Robin) Ferrier: 1932-2013.

scientific article published on 24 October 2015

Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase

scientific article published on July 2005

Structural analysis of carrageenans from the red alga, Callophyllis hombroniana Mont. Kütz (Kallymeniaceae, Rhodophyta).

scientific article published in May 2005

Structural analysis of the polysaccharide from Pachymenia lusoria (Cryptonemiaceae, Rhodophyta)

scientific article published on 01 March 1995

Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

scientific article published on 03 March 2005

Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae

scientific article published on October 2006

Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces

scientific article

Syntheses and bio-activities of the L-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases

scientific article published on 26 January 2006

Syntheses of oligomannosides in solution and on a soluble polymer support: a comparison

scientific article published on 20 December 2005

Synthesis and Herbicidal Activity of [3R,5S,6S]-3-Benzyloxy-5- methoxy-1,7-dioxaspiro[5.5]undecane and [3R,5S,6S]-3-Methoxy-5-benzyloxy-1,7-dioxaspiro[5.5]undecane.

scientific article

Synthesis and utility of sulfated chromogenic carbohydrate model substrates for measuring activities of mucin-desulfating enzymes

scientific article

Synthesis of 13 C-labelled sulfated N-acetyl-d-lactosamines to aid in the diagnosis of mucopolysaccharidosis diseases

scientific article published on 11 December 2018

Synthesis of 2-fluoroethyl beta-D-galactopyranoside and 2-fluoroethyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside from lactose using beta-D-galactosidase

scientific article published on 01 March 1994

Synthesis of Transition State Analogue Inhibitors for Purine Nucleoside Phosphorylase and N-Riboside Hydrolases

Synthesis of a Transition State Analogue Inhibitor of Purine Nucleoside Phosphorylase via the Mannich Reaction

scientific article published on 01 October 2003

Synthesis of allyl beta-D-galactopyranoside from lactose using Streptococcus thermophilus beta-D-galactosidase

scientific article published on 01 April 1996

Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase

scientific article published in November 2003

Synthesis of the enantiomers of hexahydrodibenz[d,f]azecines

scientific article published in October 2004

Synthesis studies of structural analogues of tagetitoxin: 2-phosphate

Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins

scientific article (publication date: 11 March 2005)

Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase

scientific article

The Chemistry of Castanospermine, Part IV1: Synthetic Modifications at C-8

The chemistry of castanospermine, part II: Synthesis of deoxyfluoro analogues of castanospermine

The chemistry of castanospermine, part III:1,2 Castanospermine-6-phosphate, an unusual route to a novel compound

The chemistry of castanospermine, part V: synthetic modifications at C-1 and C-7

The chemistry of castanospermine. Direct oxidation of the tetraacetate to the corresponding gamma-lactam

scientific article

The presence of gigartinine in a New Zealand Gracilaria species

article published in 2001

The synthesis and antibacterial activity of totarol derivatives. Part 1: modifications of ring-C and pro-drugs

scientific article

The synthesis and antibacterial activity of totarol derivatives. Part 2: Modifications at C-12 and O-13.

scientific article published in July 2000

The synthesis and immune stimulating action of mannose-capped lysine-based dendrimers

article published in 2009

Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase

scientific article published on February 2009

Transition state analogue discrimination by related purine nucleoside phosphorylases

scientific article

Transition state analogue inhibitors of N-ribosyltransferases: new drugs by targeting nucleoside processing enzymes

scientific article published in January 2007

Transition state analogue inhibitors of protozoan nucleoside hydrolases

scientific article published on 01 November 1999

Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum

scientific article published on 13 November 2001

Transition state analogues in quorum sensing and SAM recycling

scientific article published on January 2008

Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis

scientific article

Using gigartinine to track the distribution of an alien species of Gracilaria in New Zealand

article

Validation of an LC-MS/MS assay for detecting relevant disaccharides from keratan sulfate as a biomarker for Morquio A syndrome

scientific article published on 01 August 2011

Xylan from Leptosarca simplex and carrageenan from Iridea, Cenacrum, and Nemastoma species from the subantarctic islands of New Zealand

Scholarly article from 1988

l -Enantiomers of Transition State Analogue Inhibitors Bound to Human Purine Nucleoside Phosphorylase

scientific article

List of works by Richard Furneaux

(1R,2R,3S,5R,6R,7S,9aR,10aR)-4a,8a-Diazaperhydroanthracene-1,2,3,5,6,7-hexaol

1,3-Dideoxynojirimycin-3-yl glycosides of beta-(1-->3)- and beta-(1-->6)-linked gluco-oligosaccharides

1-Deoxy-D-galactonojirimycins with dansyl capped N-substituents as β-galactosidase inhibitors and potential probes for GM1 gangliosidosis affected cell lines.

1-Deoxynojirimycins with dansyl capped N-substituents as probes for Morbus Gaucher affected cell lines

8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases

A fluorescent probe for GM1 gangliosidosis related β-galactosidase: N-(dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino-D-galactitol

A novel and simple colorimetric method for screening Giardia intestinalis and anti-giardial activity in vitro

A novel mechanism for desulfation of mucin: identification and cloning of a mucin-desulfating glycosidase (sulfoglycosidase) from Prevotella strain RS2

A novel phosphatidylinositol manno-oligosaccharide (dPIM-8) from Gordonia sputi

A practical synthesis of (3R,4R)-N-tert-butoxycarbonyl-4-hydroxymethylpyrrolidin-3-ol

A procedure for the analysis of glycosaminoglycan mixtures based on digestion by specific enzymes

A simple synthesis of 8-(methoxycarbonyl)octyl 3,6-di-O-(alpha-D-mannopyranosyl)-alpha-D-mannopyranoside and derivatives and their use in the preparation of neoglycoconjugates

A synchrotron radiation study of the one-dimensional complex of sodium with (1S)-N-carboxylato-1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol, a member of the 'immucillin' family

Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase

Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: convergent synthesis of the aza-C-nucleoside immucillins.

Alkyl 4-chlorobenzoyloxycarbamates as highly effective nitrogen source reagents for the base-free, intermolecular aminohydroxylation reaction

Analysis of pyruvylated beta-carrageenan by 2D NMR spectroscopy and reductive partial hydrolysis

Approaches to the Synthesis of Glycosides

Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs.

Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase

Azetidine based transition state analogue inhibitors of N-ribosyl hydrolases and phosphorylases

Carrageenans from the tetrasporic stages of Gigartina clavifera and Gigartina alveata (Gigartinaceae, Rhodophyta)

Chemical and spectroscopic characterisation of the phosphatidylinositol manno-oligosaccharides from Mycobacterium bovis AN5 and WAg201 and Mycobacterium smegmatis mc2 155

Chemical methods for the analysis of sulphated galactans from red algae

Chemotaxonomy of New Zealand red algae in the family Gigartinaceae (Rhodophyta) based on galactan structures from the tetrasporophyte life-stage

Corrigendum to “Synthesis and utility of sulfated chromogenic carbohydrate model substrates for measuring activities of mucin-desulfating enzymes”

Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,)

Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases.

Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.

Femtomolar transition state analogue inhibitors of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli

Glucofuranosylation with penta-O-propanoyl-beta-D-glucofuranose.

Imino-C-nucleoside synthesis: heteroaryl lithium carbanion additions to a carbohydrate cyclic imine and nitrone

Iminoribitol Transition State Analogue Inhibitors of Protozoan Nucleoside Hydrolases†

Improved Syntheses of 3H,5H-Pyrrolo[3,2-d]pyrimidines

Inhibition and Structure of Trichomonas vaginalis Purine Nucleoside Phosphorylase with Picomolar Transition State Analogues †

Inhibition of angiogenesis by oral ingestion of powdered shark cartilage in a rat model

Inhibition of ricin A-chain with pyrrolidine mimics of the oxacarbenium ion transition state.

Inhibitors of ADP-ribosylating bacterial toxins based on oxacarbenium ion character at their transition states

Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases

Isozyme-specific transition state inhibitors for the trypanosomal nucleoside hydrolases

Mannosylated liposomes as antigen delivery vehicles for targeting to dendritic cells

One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase

Optimization of alkyl beta-D-galactopyranoside synthesis from lactose using commercially available beta-galactosidases

Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase

Picomolar inhibitors as transition-state probes of 5'-methylthioadenosine nucleosidases

Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A

Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function

Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts

Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase

Ricin A-chain inhibitors resembling the oxacarbenium ion transition state

Robert John (Robin) Ferrier: 1932-2013.

Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase

Structural analysis of carrageenans from the red alga, Callophyllis hombroniana Mont. Kütz (Kallymeniaceae, Rhodophyta).

Structural analysis of the polysaccharide from Pachymenia lusoria (Cryptonemiaceae, Rhodophyta)

Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae

Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces

Syntheses and bio-activities of the L-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases

Syntheses of oligomannosides in solution and on a soluble polymer support: a comparison

Synthesis and Herbicidal Activity of [3R,5S,6S]-3-Benzyloxy-5- methoxy-1,7-dioxaspiro[5.5]undecane and [3R,5S,6S]-3-Methoxy-5-benzyloxy-1,7-dioxaspiro[5.5]undecane.

Synthesis and utility of sulfated chromogenic carbohydrate model substrates for measuring activities of mucin-desulfating enzymes

Synthesis of 13 C-labelled sulfated N-acetyl-d-lactosamines to aid in the diagnosis of mucopolysaccharidosis diseases

Synthesis of 2-fluoroethyl beta-D-galactopyranoside and 2-fluoroethyl 6-O-beta-D-galactopyranosyl-beta-D-galactopyranoside from lactose using beta-D-galactosidase

Synthesis of Transition State Analogue Inhibitors for Purine Nucleoside Phosphorylase and N-Riboside Hydrolases

Synthesis of a Transition State Analogue Inhibitor of Purine Nucleoside Phosphorylase via the Mannich Reaction

Synthesis of allyl beta-D-galactopyranoside from lactose using Streptococcus thermophilus beta-D-galactosidase

Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase

Synthesis of the enantiomers of hexahydrodibenz[d,f]azecines

Synthesis studies of structural analogues of tagetitoxin: 2-phosphate

Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins

Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase

The Chemistry of Castanospermine, Part IV1: Synthetic Modifications at C-8

The chemistry of castanospermine, part II: Synthesis of deoxyfluoro analogues of castanospermine

The chemistry of castanospermine, part III:1,2 Castanospermine-6-phosphate, an unusual route to a novel compound

The chemistry of castanospermine, part V: synthetic modifications at C-1 and C-7

The chemistry of castanospermine. Direct oxidation of the tetraacetate to the corresponding gamma-lactam

The presence of gigartinine in a New Zealand Gracilaria species

The synthesis and antibacterial activity of totarol derivatives. Part 1: modifications of ring-C and pro-drugs

The synthesis and antibacterial activity of totarol derivatives. Part 2: Modifications at C-12 and O-13.