Search filters

List of works by Laura Pasqualucci

A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.

scientific article

AID is required for germinal center-derived lymphomagenesis

scientific article published on 9 December 2007

Aberrant somatic hypermutation in multiple subtypes of AIDS-associated non-Hodgkin lymphoma

scientific article published on 24 April 2003

Aberrant somatic hypermutation in post-transplant lymphoproliferative disorders

scientific article

Aberrant somatic hypermutation in transformation of follicular lymphoma and chronic lymphocytic leukemia to diffuse large B-cell lymphoma.

scientific article published in October 2006

Alteration of BIRC3 and multiple other NF-κB pathway genes in splenic marginal zone lymphoma

scientific article published on 31 August 2011

An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression

scientific article published on 23 April 2015

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation

scientific article

Analysis of the coding genome of diffuse large B-cell lymphoma

scientific article

BCL-6 mutations are associated with immunoglobulin variable heavy chain mutations in B-cell chronic lymphocytic leukemia

scientific article (publication date: 15 October 2000)

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

scientific article

BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma

scientific article published on 23 June 2009

BLIMP1 is a tumor suppressor gene frequently disrupted in activated B cell-like diffuse large B cell lymphoma

scientific article published on December 2010

BRAF mutations in hairy-cell leukemia

scientific article

Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML.

scientific article published on 2 February 2006

Combined genetic inactivation of β2-Microglobulin and CD58 reveals frequent escape from immune recognition in diffuse large B cell lymphoma

scientific article

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype

scientific article

Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia

scientific article published on 3 February 2012

Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis.

scientific article

Emerging epigenetic-modulating therapies in lymphoma

scientific article published on 01 August 2019

Expression of the AID protein in normal and neoplastic B cells

scientific article

Expression of the IRTA1 receptor identifies intraepithelial and subepithelial marginal zone B cells of the mucosa-associated lymphoid tissue (MALT).

scientific article

Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015.

scientific article

Fractal-like distributions over the rational numbers in high-throughput biological and clinical data

scientific article

Genetic and phenotypic analysis of B-cell post-transplant lymphoproliferative disorders provides insights into disease biology

scientific article published in December 2008

Genetic basis of PD-L1 overexpression in diffuse large B-cell lymphomas

scientific article published on 30 March 2016

Genetic drivers of NF-κB deregulation in diffuse large B-cell lymphoma

scientific article

Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness

scientific article published on 18 February 2014

Genetics of diffuse large B cell lymphoma

scientific article published on 17 April 2018

Genetics of follicular lymphoma transformation

scientific article

Genomic analysis of non-splenic marginal zone lymphomas (MZL) indicates similarities between nodal and extranodal MZL and supports their derivation from memory B-cells

scientific article published on 25 August 2011

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

scientific article (publication date: 19 July 2001)

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

scientific article (publication date: 10 March 2011)

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

scientific article

Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

scientific article

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

scientific article

MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis

scientific article published on 01 September 2018

MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma

scientific article

Molecular pathogenesis of germinal center-derived B cell lymphomas

scientific article published on 01 March 2019

Molecular pathogenesis of non-Hodgkin's lymphoma: the role of Bcl-6

scientific article

MutComFocal: an integrative approach to identifying recurrent and focal genomic alterations in tumor samples

scientific article

Mutated nucleophosmin detects clonal multilineage involvement in acute myeloid leukemia: Impact on WHO classification

scientific article published on 22 August 2006

Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia

scientific article

Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma

scientific article published on 19 December 2002

Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness

scientific article (publication date: 28 October 2011)

On statistical modeling of sequencing noise in high depth data to assess tumor evolution

article by Raúl Rabadán et al published July 2018 in Journal of Statistical Physics

PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells

scientific article

SAVI: a statistical algorithm for variant frequency identification

scientific article

Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program

scientific article

SnapShot: diffuse large B cell lymphoma

scientific article

Somatic CLL mutations occur at multiple distinct hematopoietic maturation stages: documentation and cautionary note regarding cell fraction purity

scientific article published on 5 December 2017

Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation

scientific article published on 10 November 2009

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition

scientific article published on 31 May 2017

The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma

scientific article published on 9 January 2017

The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development

scientific article

The genetic landscape of diffuse large B-cell lymphoma

scientific article

Towards patient-based cancer therapeutics

scientific article

Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia

scientific article

Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype

scientific article

Paulina is supported by:

About Paulina

Help