List of works - Kay Diederichs

Amino Acid Templating Mechanisms in Selection of Nucleotides Opposite Abasic Sites by a Family A DNA Polymerase ⬇️

scientific article published on February 7, 2012

Arginine-induced conformational change in the c-ring/a-subunit interface of ATP synthase

scientific article

Assessing and maximizing data quality in macromolecular crystallography

scientific article

Carboplatin binding to histidine

scientific article

Cation-pi interactions as determinants for binding of the compatible solutes glycine betaine and proline betaine by the periplasmic ligand-binding protein ProX from Escherichia coli

scientific article

Chorismatase Mechanisms Reveal Fundamentally Different Types of Reaction in a Single Conserved Protein Fold

scientific article

Complete ion-coordination structure in the rotor ring of Na+-dependent F-ATP synthases

scientific article

Crystal structure analysis of the exocytosis-sensitive phosphoprotein, pp63/parafusin (phosphoglucomutase), from Paramecium reveals significant conformational variability

scientific article

Crystal structure of Ca2+/H+ antiporter protein YfkE reveals the mechanisms of Ca2+ efflux and its pH regulation

scientific article

Crystal structure of a major outer membrane protein from Thermus thermophilus HB27

scientific article

Crystal structure of oxidized flavodoxin, an essential protein in Helicobacter pylori

scientific article

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

scientific article

Data publication with the structural biology data grid supports live analysis

scientific article

Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB.

scientific article

Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex

scientific article

Human DNA Polymerase Mutations Allowing Efficient Abasic Site Bypass

scientific article

Interactions of non-polar and “Click-able” nucleotides in the confines of a DNA polymerase active site ⬇️

scientific article published on July 6, 2012

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry ⬇️

scientific article published on June 3, 2012

Learning from directed evolution: Thermus aquaticus DNA polymerase mutants with translesion synthesis activity

scientific article

Linking Crystallographic Model and Data Quality ⬇️

scientific article (publication date: 25 May 2012)

Mechanistic implications for the chorismatase FkbO based on the crystal structure

scientific article

Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights ⬇️

scientific article published on May 30, 2011

Omp85(Tt) from Thermus thermophilus HB27: an ancestral type of the Omp85 protein family

scientific article

Replication through an abasic DNA lesion: structural basis for adenine selectivity

scientific article

Structural Insights into DNA Replication without Hydrogen Bonds

scientific article

Structural Insights into Nonspecific Binding of DNA by TrmBL2, an Archaeal Chromatin Protein

scientific article

Structural and Functional Analysis of the NLRP4 Pyrin Domain

scientific article

Structural and Kinetic Analysis of Bacillus subtilis N-Acetylglucosaminidase Reveals a Unique Asp-His Dyad Mechanism

scientific article

Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase ⬇️

scientific article published on December 14, 2010

Structural basis of assembly chaperone- mediated snRNP formation

scientific article

Structural basis of multivalent binding to wheat germ agglutinin

scientific article

Structure and Interactions of NCAM Ig1-2-3 Suggest a Novel Zipper Mechanism for Homophilic Adhesion ⬇️

scientific article published on October 1, 2003

Structure and function of an RNA-reading thermostable DNA polymerase

scientific article

Structure of BamA, an essential factor in outer membrane protein biogenesis

scientific article

Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase

scientific article

Structure of the dissimilatory sulfite reductase from the hyperthermophilic archaeon Archaeoglobus fulgidus

scientific article

Structures of DNA polymerases caught processing size-augmented nucleotide probes

scientific article

Structures of KOD and 9°N DNA polymerases complexed with primer template duplex

scientific article

Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates ⬇️

scientific article published on April 11, 2012

Ternary structure reveals mechanism of a membrane diacylglycerol kinase

scientific article

The AcrB efflux pump: conformational cycling and peristalsis lead to multidrug resistance

scientific article

The crystal structure of the ligand-binding module of human TAG-1 suggests a new mode of homophilic interaction

scientific article

The three-dimensional structure of TrmB, a transcriptional regulator of dual function in the hyperthermophilic archaeonPyrococcus furiosusin complex with sucrose

scientific article

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

scientific article

X-ray structures of the maltose-maltodextrin-binding protein of the thermoacidophilic bacterium Alicyclobacillus acidocaldarius provide insight into acid stability of proteins

scientific article

Yeast D-amino acid oxidase: structural basis of its catalytic properties

scientific article

List of works by Kay Diederichs

Amino Acid Templating Mechanisms in Selection of Nucleotides Opposite Abasic Sites by a Family A DNA Polymerase ⬇️

Arginine-induced conformational change in the c-ring/a-subunit interface of ATP synthase

Assessing and maximizing data quality in macromolecular crystallography

Carboplatin binding to histidine

Cation-pi interactions as determinants for binding of the compatible solutes glycine betaine and proline betaine by the periplasmic ligand-binding protein ProX from Escherichia coli

Chorismatase Mechanisms Reveal Fundamentally Different Types of Reaction in a Single Conserved Protein Fold

Complete ion-coordination structure in the rotor ring of Na+-dependent F-ATP synthases

Crystal structure analysis of the exocytosis-sensitive phosphoprotein, pp63/parafusin (phosphoglucomutase), from Paramecium reveals significant conformational variability

Crystal structure of Ca2+/H+ antiporter protein YfkE reveals the mechanisms of Ca2+ efflux and its pH regulation

Crystal structure of a major outer membrane protein from Thermus thermophilus HB27

Crystal structure of oxidized flavodoxin, an essential protein in Helicobacter pylori

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

Data publication with the structural biology data grid supports live analysis

Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB.

Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex

Human DNA Polymerase Mutations Allowing Efficient Abasic Site Bypass

Interactions of non-polar and “Click-able” nucleotides in the confines of a DNA polymerase active site ⬇️

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry ⬇️

Learning from directed evolution: Thermus aquaticus DNA polymerase mutants with translesion synthesis activity

Linking Crystallographic Model and Data Quality ⬇️

Mechanistic implications for the chorismatase FkbO based on the crystal structure

Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights ⬇️

Omp85(Tt) from Thermus thermophilus HB27: an ancestral type of the Omp85 protein family

Replication through an abasic DNA lesion: structural basis for adenine selectivity

Structural Insights into DNA Replication without Hydrogen Bonds

Structural Insights into Nonspecific Binding of DNA by TrmBL2, an Archaeal Chromatin Protein

Structural and Functional Analysis of the NLRP4 Pyrin Domain

Structural and Kinetic Analysis of Bacillus subtilis N-Acetylglucosaminidase Reveals a Unique Asp-His Dyad Mechanism

Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase ⬇️

Structural basis of assembly chaperone- mediated snRNP formation

Structural basis of multivalent binding to wheat germ agglutinin

Structure and Interactions of NCAM Ig1-2-3 Suggest a Novel Zipper Mechanism for Homophilic Adhesion ⬇️

Structure and function of an RNA-reading thermostable DNA polymerase

Structure of BamA, an essential factor in outer membrane protein biogenesis

Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase

Structure of the dissimilatory sulfite reductase from the hyperthermophilic archaeon Archaeoglobus fulgidus

Structures of DNA polymerases caught processing size-augmented nucleotide probes

Structures of KOD and 9°N DNA polymerases complexed with primer template duplex

Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates ⬇️

Ternary structure reveals mechanism of a membrane diacylglycerol kinase

The AcrB efflux pump: conformational cycling and peristalsis lead to multidrug resistance

The crystal structure of the ligand-binding module of human TAG-1 suggests a new mode of homophilic interaction

The three-dimensional structure of TrmB, a transcriptional regulator of dual function in the hyperthermophilic archaeonPyrococcus furiosusin complex with sucrose

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

X-ray structures of the maltose-maltodextrin-binding protein of the thermoacidophilic bacterium Alicyclobacillus acidocaldarius provide insight into acid stability of proteins

Yeast D-amino acid oxidase: structural basis of its catalytic properties