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List of works by Jean-Sébastien Rougier

Aldosterone increases voltage-gated sodium current in ventricular myocytes.

scientific article published on 20 January 2006

An African loss-of-function CACNA1C variant p.T1787M associated with a risk of ventricular fibrillation

scientific article published in Scientific Reports

Brugada Syndrome Unmasked by Accidental Inhalation of Gasoline Vapors

scientific article published on 01 October 2007

Brugada syndrome and fever: genetic and molecular characterization of patients carrying SCN5A mutations.

scientific article

Calcium/calmodulin-dependent serine protein kinase CASK modulates the L-type calcium current.

scientific article published on 5 October 2016

Calmodulin binds to the N-terminal domain of the cardiac sodium channel Nav1.5.

scientific article published on 01 December 2020

Cardiac voltage-gated calcium channel macromolecular complexes

scientific article published on 18 December 2015

Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination

scientific article

Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current

scientific journal article

Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter

scientific article published on 19 December 2019

Electrophysiological properties of mouse and epitope-tagged human cardiac sodium channel Na v1.5 expressed in HEK293 cells.

scientific article published on 13 February 2013

Functional Consequences of the SCN5A-p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice

scientific article published on 11 October 2019

Functional implications of a rare variant in the sodium channel β1B subunit (SCN1B) in a 5-month-old male sudden infant death syndrome case.

scientific article

Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells

scientific article published on 13 September 2018

Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects

scientific article published on 24 February 2014

Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6)

scientific journal article

Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac death

scientific article

Lateral Membrane-Specific MAGUK CASK Down-Regulates NaV1.5 Channel in Cardiac Myocytes.

scientific article published on 30 June 2016

Mineralocorticoid receptor is essential for corticosteroid-induced up-regulation of L-type calcium currents in cultured neonatal cardiomyocytes.

scientific article published on 27 November 2007

Modulation of Nav1.5 channel function by an alternatively spliced sequence in the DII/DIII linker region.

scientific article published on 8 February 2006

Molecular characterization of two founder mutations causing long QT syndrome and identification of compound heterozygous patients

scientific article published on 01 January 2006

PDZ domain-binding motif regulates cardiomyocyte compartment-specific NaV1.5 channel expression and function.

scientific article

Proteasome inhibitor (MG132) rescues Nav1.5 protein content and the cardiac sodium current in dystrophin-deficient mdx (5cv) mice.

scientific article published on 26 March 2013

Regulation of the cardiac sodium channel Nav1.5 by utrophin in dystrophin-deficient mice

scientific article published on 14 October 2010

Role of “non-cardiac” voltage-gated sodium channels in cardiac cells

scientific article published on August 19, 2012

Selective inhibition of persistent sodium current by F 15845 prevents ischaemia-induced arrhythmias.

scientific article published on September 2010

Stereoselective Block of hERG Channel by (S)-Methadone and QT Interval Prolongation in CYP2B6 Slow Metabolizers

scientific article published on 28 February 2007

TRPM4 channels in the cardiovascular system: physiology, pathophysiology, and pharmacology.

scientific article published on 27 June 2012

Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α2δ-1-induced downregulation of Cav1.2 channels.

scientific article

Unexpected dominance: Brugada syndrome SCN5A variants exert negative dominance via α-subunit interaction

scientific article published on 07 August 2012

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block

scientific journal article

β‐Blockers in Congenital Short‐QT Syndrome as Ion Channel Blockers

scientific article published on July 25, 2013