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List of works by Patrick Brest

A multifactorial score including autophagy for prognosis and care of COVID-19 patients

scientific article published on 29 November 2020

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

scientific article

Afa/Dr diffusely adhering Escherichia coli infection in T84 cell monolayers induces increased neutrophil transepithelial migration, which in turn promotes cytokine-dependent upregulation of decay-accelerating factor (CD55), the receptor for Afa/Dr a

scientific article

Amplification loop of the inflammatory process is induced by P2X7R activation in intestinal epithelial cells in response to neutrophil transepithelial migration

scientific article

Apoptosis and tumor cell death in response to HAMLET (human alpha-lactalbumin made lethal to tumor cells).

scientific article

Assessment of morphology, antigenicity, and nucleic acid integrity for diagnostic thyroid pathology using formalin substitute fixatives.

scientific article

Autophagy : Moving Benchside Promises to Patient Bedsides.

scientific article published on January 2015

Autophagy and SQSTM1 on the RHOA(d) again: emerging roles of autophagy in the degradation of signaling proteins

scientific article

Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.

scientific article

Can the microRNA signature distinguish between thyroid tumors of uncertain malignant potential and other well-differentiated tumors of the thyroid gland?

scientific article

Characterizing isomiR variants within the microRNA-34/449 family

scientific article published on 13 February 2017

Differential expression and regulation of ADAM17 and TIMP3 in acute inflamed intestinal epithelia

scientific article published on 19 March 2009

Escherichia coli cytotoxic necrotizing factor 1 inhibits intestinal epithelial wound healing in vitro after mechanical injury.

scientific article published on October 2004

Etiology of Crohn's disease: many roads lead to autophagy

scientific article

GC content shapes mRNA storage and decay in human cells

scientific article published on 19 December 2019

Gene expression profiling in human gastric mucosa infected with Helicobacter pylori

scientific article published on 20 July 2007

Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors

scientific article published on 11 August 2019

Germinal immunogenetics as a predictive factor for immunotherapy

scientific article published on 28 June 2019

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HAMLET (human alpha-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death

scientific article

HIF1A regulates xenophagic degradation of adherent and invasive Escherichia coli (AIEC).

scientific article published in January 2014

High expression of TRF2, SOX10, and CD10 in circulating tumor microemboli detected in metastatic melanoma patients. A potential impact for the assessment of disease aggressiveness

scientific article published on 06 March 2016

Histone deacetylase inhibitors promote the tumoricidal effect of HAMLET.

scientific article

Human polymorphonuclear leukocytes are sensitive in vitro to Helicobacter pylori vaca toxin

scientific article published in December 2006

In papillary thyroid carcinoma, TIMP-1 expression correlates with BRAF (V600E) mutation status and together with hypoxia-related proteins predicts aggressive behavior

scientific article published on 27 July 2013

Inhibition of apoptosis induced by heat shock preconditioning is associated with decreased phagocytosis in human polymorphonuclear leukocytes through inhibition of Rac and Cdc42

MiR-129-5p is required for histone deacetylase inhibitor-induced cell death in thyroid cancer cells

scholarly article by Patrick Brest et al published 26 September 2011 in Endocrine-related cancer

MiR-223-3p inhibits angiogenesis and promotes resistance to cetuximab in head and neck squamous cell carcinoma

scientific article published on 11 July 2017

MicroRNA-375/SEC23A as biomarkers of the in vitro efficacy of vandetanib.

scientific article published on 29 March 2016

Noisy silent polymorphisms

scientific article published on 28 February 2013

Open questions for harnessing autophagy-modulating drugs in the SARS-CoV-2 war: Hope or Hype?

scientific article published on 10 June 2020

Possible consequences of the COVID-19 pandemic on the use of biospecimens from cancer biobanks for research in academia and bioindustry

scientific article published on 07 May 2020

Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition.

scientific article published on 19 December 2016

Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition.

scientific article

Response of CAIX and CAXII to in vitro re-oxygenation and clinical significance of the combined expression in NSCLC patients

scientific article published on 30 July 2013

Rho GTPase is activated by cytotoxic necrotizing factor 1 in peripheral blood T lymphocytes: potential cytotoxicity for intestinal epithelial cells

scientific article published on March 2003

Risk predisposition for Crohn disease: a "ménage à trois" combining IRGM allele, miRNA and xenophagy

scientific article

Subversion of autophagy in adherent invasive Escherichia coli-infected neutrophils induces inflammation and cell death

scientific article

Thyroid tumours of uncertain malignant potential: frequency and diagnostic reproducibility

scientific article published on 20 June 2009

Two panels of plasma microRNAs as non-invasive biomarkers for prediction of recurrence in resectable NSCLC.

scientific article

VEGF-Related Germinal Polymorphisms May Identify a Subgroup of Breast Cancer Patients with Favorable Outcome under Bevacizumab-Based Therapy-A Message from COMET, a French Unicancer Multicentric Study

scientific article published on 23 November 2020

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