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List of works by Florian Grebien

A kinase-independent role for CDK8 in BCR-ABL1+ leukemia

scientific article published on 18 October 2019

A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain

scientific article

Acceleration of Bcr-Abl+ leukemia induced by deletion of JAK2.

scientific article published on 5 May 2014

Affinity purification strategies for proteomic analysis of transcription factor complexes.

scientific article published on 22 August 2013

All-trans retinoic acid enhances, and a pan-RAR antagonist counteracts, the stem cell promoting activity of EVI1 in acute myeloid leukemia

scientific article published on 10 December 2019

Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells.

scientific article published on 2 November 2016

BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia

scientific article published on 29 January 2012

Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression

scientific article published on 21 January 2021

CD14 is a coreceptor of Toll-like receptors 7 and 9. ⬇️

scientific article

CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex

scientific article published on 24 January 2019

Cell size control: new evidence for a general mechanism.

scientific article

Comprehensive assessment of differential ChIP-seq tools guides optimal algorithm selection

scientific article published on 24 May 2022

Correction: Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma

scientific article published on 14 July 2020

Correction: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation

Dependence on Myb expression is attenuated in myeloid leukaemia with N-terminal CEBPA mutations

scientific article published on 15 March 2019

Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma

scientific article published on 21 August 2018

Erratum: Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

scholarly article by Florian Grebien et al published October 2015 in Nature Chemical Biology

Erratum: STAT3 regulated ARF expression suppresses prostate cancer metastasis

scientific article published in Nature Communications

Erythroid progenitor renewal versus differentiation: genetic evidence for cell autonomous, essential functions of EpoR, Stat5 and the GR.

scientific article published on May 2006

Evaluation of Stat5 as a potential drug target in bcr/abl-induced leukemias

Gain-of-Function Effects of N-Terminal CEBPA Mutations in Acute Myeloid Leukemia

scientific article published on 23 December 2019

Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation

scientific article published on 13 October 2016

JAK-STAT signaling in cancer: From cytokines to non-coding genome.

scientific article published on 24 June 2016

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

scientific article published on 18 May 2018

NVT: a fast and simple tool for the assessment of RNA-seq normalization strategies

scientific article

Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site.

scientific article published on 31 July 2017

Optimisation of Downscaled Tandem Affinity Purifications to Identify Core Protein Complexes

scientific article published on May 2012

Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity

article

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms

scientific article

Pharmacologic inhibition of STAT5 in acute myeloid leukemia

scientific article published on 2 February 2018

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

scientific article

Roles of SETD2 in Leukemia-Transcription, DNA-Damage, and Beyond ⬇️

scientific article published on 27 February 2019

STAT3 regulated ARF expression suppresses prostate cancer metastasis

scientific article published on 22 July 2015

STAT3β is a tumor suppressor in acute myeloid leukemia

scientific article published on 01 July 2019

STAT5BN642H is a driver mutation for T cell neoplasia

scientific article published on 4 December 2017

Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2.

scientific article published on 31 January 2008

Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia

scientific article published on March 2010

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

scientific article

Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation

scientific article

Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.

scientific article

Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in Acute Myeloid Leukemia

scientific article published on 26 September 2020

Targeting allosteric regulatory modules in oncoproteins: "drugging the undruggable".

scientific article published in November 2011

Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis

scientific article

The different functions of Stat5 and chromatin alteration through Stat5 proteins

scientific article

The growing arsenal of ATP-competitive and allosteric inhibitors of BCR-ABL ⬇️

scientific article published on September 21, 2012

The phosphatase UBASH3B/Sts-1 is a negative regulator of Bcr-Abl kinase activity and leukemogenesis

scientific article published on 08 April 2019

Using iTRAQ combined with tandem affinity purification to enhance low-abundance proteins associated with somatically mutated EGFR core complexes in lung cancer.

scientific article

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