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List of works by Mark Bear

A Role for the Cytoplasmic Polyadenylation Element in NMDA Receptor-Regulated mRNA Translation in Neurons ⬇️

scientific article published on December 15, 2001

A biophysically-based neuromorphic model of spike rate- and timing-dependent plasticity ⬇️

scientific article published on November 16, 2011

A model of dendritic spine Ca2+ concentration exploring possible bases for a sliding synaptic modification threshold

scientific article

A morphological correlate of synaptic scaling in visual cortex.

scientific article

A unified model of NMDA receptor-dependent bidirectional synaptic plasticity

scientific article

Activation of mGluR5 induces rapid and long-lasting protein kinase D phosphorylation in hippocampal neurons

scientific article

Altered synaptic plasticity in a mouse model of fragile X mental retardation

scientific article

Arbaclofen in fragile X syndrome: results of phase 3 trials

scientific article

Bidirectional synaptic plasticity: from theory to reality

scientific article

Binocular competition in the control of geniculate cell size depends upon visual cortical N-methyl-D-aspartate receptor activation

scientific article

Brain-derived neurotrophic factor alters the synaptic modification threshold in visual cortex ⬇️

scientific article published on April 1, 1998

Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice

scientific article published in April 2012

Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome

scientific article

Contrasting roles for parvalbumin-expressing inhibitory neurons in two forms of adult visual cortical plasticity

scientific article published on 4 March 2016

Convergence of Hippocampal Pathophysiology in Syngap+/- and Fmr1-/y Mice

scientific article

Correction of fragile X syndrome in mice.

scientific article

Deprivation-induced synaptic depression by distinct mechanisms in different layers of mouse visual cortex

scholarly article

Developmental inhibitory gate controls the relay of activity to the superficial layers of the visual cortex

scientific article (publication date: September 2001)

Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice

scientific article published on 01 July 2020

Dynamic Changes in the Bridging Collaterals of the Basal Ganglia Circuitry Control Stress-Related Behaviors in Mice

scientific article published on 14 January 2020

Effect of transgenic overexpression of NR2B on NMDA receptor function and synaptic plasticity in visual cortex ⬇️

scientific article published on November 1, 2001

Effects of age and visual experience on [3H] MK801 binding to NMDA receptors in the kitten visual cortex ⬇️

scientific article published on 01 January 1991

Effects of the Metabotropic Glutamate Receptor Antagonist MCPG on Phosphoinositide Turnover and Synaptic Plasticity in Visual Cortex ⬇️

scientific article published on January 1, 1998

Experience-Dependent Synaptic Plasticity in V1 Occurs without Microglial CX3CR1.

scientific article published on 26 September 2017

Experience-dependent modification of synaptic plasticity in visual cortex

scientific article

Experience-dependent modifications of kitten striate cortex are not prevented by thalamic lesions that include the intralaminar nuclei ⬇️

scientific article published on January 1, 1988

Extinction of an instrumental response: a cognitive behavioral assay in Fmr1 knockout mice

scientific article

Fragile X mental retardation protein and synaptic plasticity

scientific article published on 08 April 2013

Fragile X: translation in action

scientific article

Fragile x syndrome and autism: from disease model to therapeutic targets

scientific article

Heterosynaptic metaplasticity in the hippocampus in vivo: a BCM-like modifiable threshold for LTP.

scientific article

Higher brain functions served by the lowly rodent primary visual cortex

scientific article

Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade

scientific article

Homosynaptic long-term depression in the visual cortex

scientific article

Homosynaptic long-term depression: a mechanism for memory?

scientific article

How the mechanisms of long-term synaptic potentiation and depression serve experience-dependent plasticity in primary visual cortex

scientific article

Internalization of ionotropic glutamate receptors in response to mGluR activation ⬇️

scientific article published on November 1, 2001

Interneuron Simplification and Loss of Structural Plasticity As Markers of Aging-Related Functional Decline

scientific article published on 14 August 2018

LTP and LTD

scientific article

Learned spatiotemporal sequence recognition and prediction in primary visual cortex

scientific article

Learning induces long-term potentiation in the hippocampus

scientific article (publication date: 25 August 2006)

Long-Term Potentiation of Thalamocortical Transmission in the Adult Visual CortexIn Vivo ⬇️

scientific article published on December 15, 2001

Loss of Arc renders the visual cortex impervious to the effects of sensory experience or deprivation

scientific article

Loss of the fragile X mental retardation protein decouples metabotropic glutamate receptor dependent priming of long-term potentiation from protein synthesis

scientific article

Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome

scientific article

Mechanism for a sliding synaptic modification threshold

scientific article

Mechanism-based approaches to treating fragile X

scientific article

Metabotropic glutamate receptor signaling is required for NMDA receptor-dependent ocular dominance plasticity and LTD in visual cortex

scientific article

Microchip amplifier for in vitro, in vivo, and automated whole cell patch-clamp recording.

scientific article

Modulation of long-term synaptic depression in visual cortex by acetylcholine and norepinephrine

scientific article

Molecular basis for induction of ocular dominance plasticity

scientific article

Monocular deprivation induces homosynaptic long-term depression in visual cortex

scientific article

Mutations causing syndromic autism define an axis of synaptic pathophysiology

scientific article published on 23 November 2011

Negative Allosteric Modulation of mGluR5 Partially Corrects Pathophysiology in a Mouse Model of Rett Syndrome.

scientific article

Obligatory role of NR2A for metaplasticity in visual cortex

scientific article

Pharmacological reversal of synaptic plasticity deficits in the mouse model of fragile X syndrome by group II mGluR antagonist or lithium treatment

scientific article

Rapid structural remodeling of thalamocortical synapses parallels experience-dependent functional plasticity in mouse primary visual cortex

scientific article

Role for A kinase-anchoring proteins (AKAPS) in glutamate receptor trafficking and long term synaptic depression

scientific article (publication date: 29 April 2005)

Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome

scientific article published on 01 May 2020

Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.

scientific article

Somatostatin-like immunoreactivity in the forebrain of Pseudemys turtles ⬇️

scientific article published on June 1, 1983

Spatial Multiplexing of Fluorescent Reporters for Imaging Signaling Network Dynamics

scientific article published on 17 November 2020

Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome

scientific article published on 01 May 2019

Synaptic plasticity in visual cortex: comparison of theory with experiment ⬇️

scientific article published on November 1, 1991

The Autistic Neuron: Troubled Translation?

scientific article

The mGluR theory of fragile X mental retardation

scientific article (publication date: July 2004)

The pathophysiology of fragile X (and what it teaches us about synapses)

scientific article

Toward Fulfilling the Promise of Molecular Medicine in Fragile X Syndrome ⬇️

scientific article published on January 1, 2011

Translating Glutamate: From Pathophysiology to Treatment ⬇️

scientific article published on September 28, 2011

Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression

scientific journal article

Visual experience and deprivation bidirectionally modify the composition and function of NMDA receptors in visual cortex

scientific article

Visual experience induces long-term potentiation in the primary visual cortex

scientific article

Visual experience regulates gene expression in the developing striate cortex

scientific article

Visual recognition memory, manifested as long-term habituation, requires synaptic plasticity in V1

scientific article

β-Arrestin2 Couples Metabotropic Glutamate Receptor 5 to Neuronal Protein Synthesis and Is a Potential Target to Treat Fragile X.

scientific article

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