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List of works by Mathias Winterhalter

A general approach to protein folding using thermostable exoshells

scientific article published in 2021

A long-lived amphiphilic fluorescent probe studied in POPC air-water monolayer and solution bilayer systems

scientific article published in November 2001

A nanocompartment system (Synthosome) designed for biotechnological applications

scientific article published on 20 December 2005

Amphiphilic block copolymer nanocontainers as bioreactors

article published in 2001

Ampicillin permeation across OmpF, the major outer-membrane channel in

scientific article published in Journal of Biological Chemistry

Analysis of fast channel blockage: revealing substrate binding in the microsecond range

Antibiotic Uptake through Membrane Channels: Role of Providencia stuartii OmpPst1 Porin in Carbapenem Resistance

scientific article published on 11 December 2012

Antibiotic permeation across the OmpF channel: modulation of the affinity site in the presence of magnesium

scientific article

Antibiotic translocation through membrane channels: temperature-dependent ion current fluctuation for catching the fast events.

scientific article

Antibiotic translocation through porins studied in planar lipid bilayers using parallel platforms

scientific article published on 02 April 2015

Bacterial Outer Membrane Porins as Electrostatic Nanosieves: Exploring Transport Rules of Small Polar Molecules.

scientific article

Bending elasticity of electrically charged bilayers: coupled monolayers, neutral surfaces, and balancing stresses

Biophysical characterization of E. coli TolC interaction with the known blocker hexaamminecobalt.

scientific article

Biophysical characterization of in- and efflux in Gram-negative bacteria

scientific article published on September 2008

Black lipid membranes

Bridging timescales and length scales: from macroscopic flux to the molecular mechanism of antibiotic diffusion through porins.

scientific article published on February 2010

Channel-forming membrane proteins as molecular sensors

scientific article published in March 2004

Chapter 2 Functionalized Liposomes

Characterization of Ciprofloxacin Permeation Pathways across the Porin OmpC Using Metadynamics and a String Method

scientific article published on 17 August 2017

Chemosensing ensembles for monitoring biomembrane transport in real time

scientific article

Chitoporin from Vibrio harveyi, a channel with exceptional sugar specificity

scientific article

Chitoporin from the Marine Bacterium Vibrio harveyi: PROBING THE ESSENTIAL ROLES OF TRP136 AT THE SURFACE OF THE CONSTRICTION ZONE.

scientific article published on 16 June 2015

Comparing the temperature-dependent conductance of the two structurally similar E. coli porins OmpC and OmpF.

scientific article published on May 2010

Complexation Mechanism of Bovine Serum Albumin and Poly(allylamine hydrochloride)

Composite Nanocapsules: Lipid Vesicles Covered with Several Layers of Crosslinked Polyelectrolytes

Computational modeling of ion transport through nanopores

article

Controlled intracellular release of peptides from microcapsules enhances antigen presentation on MHC class I molecules

scientific article published on October 2009

Controlling membrane permeability with bacterial porins: application to encapsulated enzymes

scientific article published in December 2001

Correlated trapping of sugar molecules by the trimeric protein channel  chitoporin

scientific article published on 13 September 2016

Crystal structure of a COG4313 outer membrane channel.

scientific article published on 7 July 2015

CymA of Klebsiella oxytoca outer membrane: binding of cyclodextrins and study of the current noise of the open channel

scientific article published on August 2003

Deformation of spherical vesicles by electric fields

Designed to penetrate: time-resolved interaction of single antibiotic molecules with bacterial pores

scientific article

Determination of thermodynamic parameters of Xerocomus chrysenteron lectin interactions with N-acetylgalactosamine and Thomsen-Friedenreich antigen by isothermal titration calorimetry

scientific article

Differential detergent extraction of mycobacterium marinum cell envelope proteins identifies an extensively modified threonine-rich outer membrane protein with channel activity.

scientific article published on March 2013

Docking of a single phage lambda to its membrane receptor maltoporin as a time-resolved event

scientific article

Dodecaborate cluster lipids with variable headgroups for boron neutron capture therapy: Synthesis, physical–chemical properties and toxicity

article

Draft Genome Sequence of Dietzia maris DSM 43672, a Gram-Positive Bacterium of the Mycolata Group

scientific article published on 9 June 2016

Effect of surface charge on the curvature elasticity of membranes

article

Effect of voltage on pores in membranes

scientific article published on 01 December 1987

Elastic properties of lipid bilayer containing modified lipids

Elasticity of bilayers containing PEG lipids

Electric-field-dependent thermal fluctuations of giant vesicles

article

Electronic laboratory notebooks in a public–private partnership

Electrophysiological Characterization of Transport Across Outer-Membrane Channels from Gram-Negative Bacteria in Presence of Lipopolysaccharides

scientific article published on 05 February 2020

Electroporation of curved lipid membranes in ionic strength gradients

scientific article published on 01 July 2000

Encapsulation of acetylcholinesterase in preformed liposomes

scientific article published on 01 June 2003

Encapsulation of enzymes in liposomes: high encapsulation efficiency and control of substrate permeability

scientific article

Engineering Enhanced Pore Sizes Using FhuA Δ1-160 from E. coli Outer Membrane as Template

scientific article published on 20 October 2017

Enrofloxacin Permeation Pathways across the Porin OmpC.

scientific article published on 6 January 2018

Examining noise sources at the single-molecule level: 1/f noise of an open maltoporin channel

scientific article

Facilitated permeation of antibiotics across membrane channels--interaction of the quinolone moxifloxacin with the OmpF channel

scientific article

Facilitated substrate transport through membrane proteins

scientific article published in June 2001

Fluorescence quenching as a tool to investigate quinolone antibiotic interactions with bacterial protein OmpF.

scientific article

Functional Sub-Conformations in Protein Folding: Evidence from Single-Channel Experiments

article

Functional Subconformations in Protein Folding: Evidence from Single-Channel Experiments

scientific article published in Physical Review Letters

General Method to Determine the Flux of Charged Molecules through Nanopores Applied to β-Lactamase Inhibitors and OmpF.

scientific article

Generation of artificial channels by multimerization of β-strands from natural porin

scientific article

Getting Drugs into Gram-Negative Bacteria: Rational Rules for Permeation through General Porins

scientific article published on 17 August 2018

Getting Drugs through Small Pores: Exploiting the Porins Pathway in Pseudomonas aeruginosa

scientific article published on 08 August 2018

Giant Free-Standing ABA Triblock Copolymer Membranes

article

Giant liposome microreactors for controlled production of calcium phosphate crystals

scientific article published in July 2004

Halogenated Dodecaborate Clusters as Agents to Trigger Release of Liposomal Contents

scientific article published on 12 January 2015

How beta-lactam antibiotics enter bacteria: a dialogue with the porins

scientific article

Hybrid Nanocapsules: Interactions of ABA Block Copolymers with Liposomes

scientific article published in 2005

Identification and Characterization of Approved Drugs and Drug-Like Compounds as Covalent Escherichia coli ClpP Inhibitors

scientific article published on 31 May 2019

Implication of porins in beta-lactam resistance of Providencia stuartii

scientific article

Influence of surface charges on the rupture of black lipid membranes

Interaction between quinolones antibiotics and bacterial outer membrane porin OmpF

Interaction of N,N,N-trialkylammonioundecahydro-closo-dodecaborates with dipalmitoyl phosphatidylcholine liposomes

scientific article

Interaction of Na2B12H11SH with dimyristoyl phosphatidylcholine liposomes

scientific article published on 30 November 2008

Interaction of bacteriophage lambda with its cell surface receptor: an in vitro study of binding of the viral tail protein gpJ to LamB (Maltoporin).

scientific article published on February 2006

Interaction of cephalosporins with outer membrane channels of Escherichia coli. Revealing binding by fluorescence quenching and ion conductance fluctuations

scientific article published on 10 December 2010

Interaction of poly(ethylene-glycols) with air-water interfaces and lipid monolayers: investigations on surface pressure and surface potential

scientific article

Interaction of protamine with gram-negative bacteria membranes: possible alternative mechanisms of internalization in Escherichia coli, Salmonella typhimurium and Pseudomonas aeruginosa

scientific article published on 22 January 2014

Interaction of the Effector Domain of MARCKS and MARCKS-Related Protein with Lipid Membranes Revealed by Electric Potential Measurements†

scientific article published in 1998

Interaction of zwitterionic penicillins with the OmpF channel facilitates their translocation

scientific article

Interactions of mitochondrial presequence peptides with the mitochondrial outer membrane preprotein translocase TOM.

scientific article published on August 2010

Ion Channels Made from a Single Membrane-Spanning DNA Duplex

scientific article

Kinetics of pore size during irreversible electrical breakdown of lipid bilayer membranes

scientific article published on January 1993

Large-Conductance Transmembrane Porin Made from DNA Origami

scientific article (publication date: 27 September 2016)

Lipid membranes in external electric fields: kinetics of large pore formation causing rupture

scientific article published on 16 January 2014

Liposome retention in size exclusion chromatography

scientific article

Liposome stability and formation: experimental parameters and theories on the size distribution

scientific article

Liposome-Based Nanocapsules

scientific article published on 01 March 2004

Liposomes : support à la formation de capsules plus stables à base de polyéléctrolytes réticulés ou de silice

scientific article published on 01 March 2007

MOMP from Campylobacter jejuni Is a Trimer of 18-Stranded β-Barrel Monomers with a Ca2+ Ion Bound at the Constriction Zone

scientific article

Mechanisms of intrinsic resistance and acquired susceptibility of Pseudomonas aeruginosa isolated from cystic fibrosis patients to temocillin, a revived antibiotic

scientific article published on 16 January 2017

Membrane channels as a tool to control nanoreactors

scientific article published on August 2006

Microstructured liposome array

scientific article

Miniaturized planar lipid bilayer: increased stability, low electric noise and fast fluid perfusion

scientific article published on 31 October 2007

Model-free analysis of binding at lipid membranes employing micro-calorimetric measurements

scientific article published on 8 March 2007

Modulation of enrofloxacin binding in OmpF by Mg2+ as revealed by the analysis of fast flickering single-porin current

scientific article

Molecular Basis of Filtering Carbapenems by Porins from β-Lactam-resistant Clinical Strains of Escherichia coli

scientific article

Molecular analysis of antimicrobial agent translocation through the membrane porin BpsOmp38 from an ultraresistant Burkholderia pseudomallei strain

scientific article

Molecular basis of enrofloxacin translocation through OmpF, an outer membrane channel of Escherichia coli--when binding does not imply translocation.

scientific article published in April 2010

Molecular origin of the cation selectivity in OmpF porin: single channel conductances vs. free energy calculation

scientific article published in July 2003

Molecular uptake of chitooligosaccharides through chitoporin from the marine bacterium Vibrio harveyi

scientific article

Multifunctionalized polymer microcapsules: novel tools for biological and pharmacological applications

scientific article published on June 2007

Nanoaggregates of micropurified lipopolysaccharide identified using dynamic light scattering, zeta potential measurement, and TLR4 signaling activity

scientific article published on 6 September 2012

Nanocapsules with functionalized surfaces and walls.

scientific article published in March 2004

Nanoengineered polymer capsules: tools for detection, controlled delivery, and site-specific manipulation

scientific article published in February 2005

Nanoplasmonically-induced defects in lipid membrane monitored by ion current: transient nanopores versus membrane rupture

scientific article

Nanopores: maltoporin channel as a sensor for maltodextrin and lambda-phage

scientific article

Nanoreactors based on (polymerized) ABA-triblock copolymer vesicles

Nanoreactors from Polymer-Stabilized Liposomes

New developments in nanopore research—from fundamentals to applications

Noise analysis of antibiotic permeation through bacterial channels

On the defect growth after short electric field pulses in planar lipid bilayers

On the dynamics of the electric field induced breakdown in lipid membranes

article

On translocation through a membrane channel via an internal binding site: kinetics and voltage dependence

scientific article

Oriented channels reveal asymmetric energy barriers for sugar translocation through maltoporin of Escherichia coli

scientific article

Outer-membrane translocation of bulky small molecules by passive diffusion

scientific article published on 26 May 2015

Peptide translocation across MOMP, the major outer membrane channel from Campylobacter jejuni

scientific article published on 23 June 2017

Peptide translocation through the mesoscopic channel: binding kinetics at the single molecule level

Permeation of antibiotics through Escherichia coli OmpF and OmpC porins: screening for influx on a single-molecule level

scientific article

Permeation through nanochannels: revealing fast kinetics

article published in 2010

Pharmacological aspects of release from microcapsules - from polymeric multilayers to lipid membranes

scientific article

Physical methods to quantify small antibiotic molecules uptake into Gram-negative bacteria

scientific article published on 30 May 2015

Polydopamine Coating To Stabilize a Free-Standing Lipid Bilayer for Channel Sensing

scientific article

Polydopamine Films from the Forgotten Air/Water Interface.

scientific article published on 24 September 2014

Polyelectrolyte-coated unilamellar nanometer-sized magnetic liposomes

scientific article

Polymer Capsules and Electroporation

Polymer induced fusion and leakage of small unilamellar phospholipid vesicles: effect of surface grafted polyethylene-glycol in the presence of free PEG

Polypeptide Translocation Through the Mitochondrial TOM Channel: Temperature-Dependent Rates at the Single-Molecule Level

scientific article published on 17 December 2012

Pore forming activity of the potent RTX-toxin produced by pediatric pathogen Kingella kingae: Characterization and comparison to other RTX-family members

scientific article published on 7 April 2015

Porin flexibility in Providencia stuartii: cell-surface-exposed loops L5 and L7 are markers of Providencia porin OmpPst1.

scientific article published on 30 May 2017

Porin involvement in cephalosporin and carbapenem resistance of Burkholderia pseudomallei

scientific article (publication date: 2014)

Porin self-association enables cell-to-cell contact in Providencia stuartii floating communities.

scientific article

Pressure-Controlled versus Volume-Controlled One-Lung Ventilation for MIDCAB

article by C. Heimberg et al published December 2006 in The Thoracic and Cardiovascular Surgeon

Probing sugar translocation through maltoporin at the single channel level

scientific article

Probing the Transport of Ionic Liquids in Aqueous Solution through Nanopores

article

Probing the orientation of reconstituted maltoporin channels at the single-protein level

scientific article published on 30 June 2003

Probing the stability of S-layer-supported planar lipid membranes

scientific article published on 01 January 1999

Probing transport of charged β-lactamase inhibitors through OmpC, a membrane channel from E. coli

scientific article published on 18 January 2017

Probing transport of fosfomycin through substrate specific OprO and OprP from Pseudomonas aeruginosa

scientific article

Protection of mammalian cell used in biosensors by coating with a polyelectrolyte shell

scientific article published on 15 August 2005

Protein A Functionalized Polyelectrolyte Microcapsules as a Universal Platform for Enhanced Targeting of Cell Surface Receptors

scientific article published on 14 March 2017

Protein encapsulation in liposomes: efficiency depends on interactions between protein and phospholipid bilayer

scientific article

Protein reconstitution into freestanding planar lipid membranes for electrophysiological characterization

scientific article published on 31 December 2014

Protein translocation through Tom40: kinetics of peptide release

scientific article published on 3 January 2012

Pulling Peptides across Nanochannels: Resolving Peptide Binding and Translocation through the Hetero-oligomeric Channel from Nocardia farcinica

article by Pratik Raj Singh et al published 12 November 2012 in ACS Nano

Pyridinium lipids with the dodecaborate cluster as polar headgroup: synthesis, characterization of the physical-chemical behavior, and toxicity in cell culture

scientific article published on November 2009

Quantification of Fluoroquinolone Uptake through the Outer Membrane Channel OmpF of Escherichia coli

scientific article

Raman imaging and photodegradation study of phthalocyanine containing microcapsules and coated particles

article published in 2011

Reconstitution of Channel Proteins in (Polymerized) ABA Triblock Copolymer Membranes

scientific article published on 01 December 2000

Relationship between the Growth Regime of Polyelectrolyte Multilayers and the Polyanion/Polycation Complexation Enthalpy

article

Retrieval of a Metabolite from Cells with Polyelectrolyte Microcapsules

article

Robotic voltammetry with carbon nanotube-based sensors: a superb blend for convenient high-quality antimicrobial trace analysis

scientific article

Role of Electroosmosis in the Permeation of Neutral Molecules: CymA and Cyclodextrin as an Example

scientific article

Rupture of lipid membranes

Sensing Single Molecule Penetration into Nanopores: Pushing the Time Resolution to the Diffusion Limit

scientific article published on 21 July 2017

Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade

scientific article published on 02 March 2020

Simple reconstitution of protein pores in nano lipid bilayers

scientific article

Single Residue Acts as Gate in OccK Channels

scientific article

Single-strand DNA translation initiation step analyzed by Isothermal Titration Calorimetry.

scientific article

Small-Molecule Permeation across Membrane Channels: Chemical Modification to Quantify Transport across OmpF

scientific article published on 27 February 2019

Spontaneous lipid vesicle fusion with electropermeabilized cells

scientific article published on 01 May 2002

Stabilization of Liposomes through Enzymatic Polymerization of DNA

article by Tristan Ruysschaert et al published December 2006 in Nano Letters

Stabilization of planar lipid membranes: A stratified layer approach

Stable air bubbles--catch them if you can!

scientific article published in April 2006

Stable polymethacrylate nanocapsules from ultraviolet light-induced template radical polymerization of unilamellar liposomes.

scientific article published on August 2006

Static and dynamic disorder in protein folding: experiments with single maltoporin channels

Stealth® liposomes: from theory to product

Structural Insights into Outer Membrane Permeability of Acinetobacter baumannii

scientific article

Structural and thermodynamical properties of CuII amyloid-beta16/28 complexes associated with Alzheimer's disease.

scientific article published on 22 August 2006

Structural basis for nutrient acquisition by dominant members of the human gut microbiota

scientific article

Substrate-permeable encapsulation of enzymes maintains effective activity, stabilizes against denaturation, and protects against proteolytic degradation

scientific article published in December 2001

Sugar transport through channels reconstituted in planar lipid membranes

article by Mathias Winterhalter published April 1999 in Colloids and Surfaces A

Sugar transport through maltoporin of Escherichia coli. Role of polar tracks

scientific article published on June 2000

Sugar transport through maltoporin of Escherichia coli: role of the greasy slide

scientific article

Surface Potential of Lipid Monolayers with Grafted Polyethylene Glycols

Synthetic ion transporters: pore formation in bilayers via coupled activity of non-spanning cobalt-cage amphiphiles

scientific article published on 07 February 2014

TRANSLOCATION project: how to get good drugs into bad bugs

scientific article published in March 2014

The Anionic Boron Cluster (B12H11SH)2− as a Means To Trigger Release of Liposome Contents

scholarly article by Detlef Gabel et al published 15 January 2007 in ChemMedChem

The C-terminal domain of the Pseudomonas secretin XcpQ forms oligomeric rings with pore activity

scientific article

The Innovative Medicines Initiative's New Drugs for Bad Bugs programme: European public-private partnerships for the development of new strategies to tackle antibiotic resistance.

scientific article

The challenge of intracellular antibiotic accumulation, a function of fluoroquinolone influx versus bacterial efflux

scientific article published on 28 April 2020

The location of coenzyme Q10 in phospholipid membranes made of POPE: a small-angle synchrotron X-ray diffraction study

scientific article published on 4 June 2015

The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria.

scientific article

The temperature dependence of lipid membrane permeability, its quantized nature, and the influence of anesthetics

scientific article published on June 2009

Thermodynamic study of Cu2+ binding to the DAHK and GHK peptides by isothermal titration calorimetry (ITC) with the weaker competitor glycine

article published in 2011

Toward screening for antibiotics with enhanced permeation properties through bacterial porins

scientific article published on August 2010

Towards the sustainable discovery and development of new antibiotics

scientific article published in 2021

Toxins Secreted by Bacillus Isolated from Lung Adenocarcinomas Favor the Penetration of Toxic Substances

scientific article published on 23 November 2015

Transmembrane voltage sensor

Transport across the outer membrane porin of mycolic acid containing actinomycetales: Nocardia farcinica

scientific article

Transport at the nanoscale: temperature dependence of ion conductance.

scientific article

Transport of maltodextrins through maltoporin: a single-channel study

scientific article

Understanding Carbapenem Translocation through OccD3 (OpdP) of Pseudomonas aeruginosa

scientific article published on 25 April 2017

Understanding Voltage Gating of Providencia stuartii Porins at Atomic Level

scientific article

Understanding ion conductance on a molecular level: an all-atom modeling of the bacterial porin OmpF.

scientific article published on October 2009

Understanding the function of bacterial outer membrane channels by reconstitution into black lipid membranes

scientific article published on 01 July 2000

Unimolecular study of the interaction between the outer membrane protein OmpF from E. coli and an analogue of the HP(2-20) antimicrobial peptide

scientific article

Untersuchung des Energiebedarfs derbatch-Rektifikation durch einen neuen Trainingssimulator

Unusual Constriction Zones in the Major Porins OmpU and OmpT from Vibrio cholerae

scholarly article by Monisha Pathania published in May 2018

Use of irreversible electrical breakdown of lipid bilayers for the study of interaction of membranes with surface active molecules

scientific article published on 01 April 1993

p-Sulfonatocalix[6]arene is an effective coacervator of poly(allylamine hydrochloride).

scientific article published in November 2001

“To Catch or Not to Catch”: Microcapsule-Based Sandwich Assay for Detection of Proteins and Nucleic Acids

article