List of works - Gianfranco Bocchinfuso

Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease

scientific article

Germline missense mutations affecting KRAS Isoform B are associated with a severe Noonan syndrome phenotype

scientific article

Mutations in KCNH1 and ATP6V1B2 cause Zimmermann-Laband syndrome.

scientific article published on 27 April 2015

Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis

scientific article

Dual role of DNA intrinsic curvature and flexibility in determining nucleosome stability

scientific article published on 01 March 1999

Mutations in ZBTB20 cause Primrose syndrome

scientific article

Diverse driving forces underlie the invariant occurrence of the T42A, E139D, I282V and T468M SHP2 amino acid substitutions causing Noonan and LEOPARD syndromes

scientific article

Mutations Impairing GSK3-Mediated MAF Phosphorylation Cause Cataract, Deafness, Intellectual Disability, Seizures, and a Down Syndrome-like Facies

scientific article

Activating Mutations Affecting the Dbl Homology Domain of SOS2 Cause Noonan Syndrome

scientific article

Different mechanisms of action of antimicrobial peptides: insights from fluorescence spectroscopy experiments and molecular dynamics simulations.

scientific article

A restricted spectrum of mutations in the SMAD4 tumor-suppressor gene underlies Myhre syndrome

scientific article published on January 2012

Membrane thickness and the mechanism of action of the short peptaibol trichogin GA IV

scientific article published on 05 December 2012

Membrane perturbation by the antimicrobial peptide PMAP-23: a fluorescence and molecular dynamics study

scientific article

Fluorescence spectroscopy and molecular dynamics simulations in studies on the mechanism of membrane destabilization by antimicrobial peptides.

scientific article published on 17 May 2011

A new polysaccharidic gel matrix for drug delivery: preparation and mechanical properties

scientific article

A new scleroglucan/borax hydrogel: swelling and drug release studies.

scientific article published on 25 December 2004

Structural and functional effects of disease-causing amino acid substitutions affecting residues Ala72 and Glu76 of the protein tyrosine phosphatase SHP-2

scientific article published on 01 March 2007

Investigation on a new scleroglucan/borax hydrogel: structure and drug release

scientific article published on 22 May 2006

Metal binding properties of fluorescent analogues of trichogin GA IV: a conformational study by time-resolved spectroscopy and molecular mechanics investigations.

scientific article

The importance of being kinked: role of Pro residues in the selectivity of the helical antimicrobial peptide P5.

scientific article

Structural, Functional, and Clinical Characterization of a Novel PTPN11 Mutation Cluster Underlying Noonan Syndrome

scientific journal article

Novel SMAD4 mutation causing Myhre syndrome

scientific article (publication date: July 2014)

Dynamics of formation of a helix-turn-helix structure in a membrane-active peptide: a time-resolved spectroscopic study

scientific article published on 01 January 2006

Guar gum and scleroglucan interactions with borax: experimental and theoretical studies of an unexpected similarity.

scientific article published on October 2010

Counteracting effects operating on Src homology 2 domain-containing protein-tyrosine phosphatase 2 (SHP2) function drive selection of the recurrent Y62D and Y63C substitutions in Noonan syndrome

scientific article published on 18 June 2012

Molecular dynamics methods to predict peptide locations in membranes: LAH4 as a stringent test case.

scientific article

Molecular dynamics investigations of the polysaccharide scleroglucan: first study on the triple helix structure

scientific article published on 01 September 2005

Fibrils or globules? Tuning the morphology of peptide aggregates from helical building blocks.

scientific article published on 26 April 2013

Peptide folding dynamics: a time-resolved study from the nanosecond to the microsecond time regime

scientific article published on 01 November 2006

Versatile hydrogels: an efficient way to clean paper artworks

article

Photophysical properties of 1,3,5-tris(2-naphthyl)benzene and related less-arylated compounds: experimental and theoretical investigations

scientific article published in December 2009

Theoretical and experimental study on a self-assembling polysaccharide forming nanochannels: static and dynamic effects induced by a soft confinement

scientific article published on 17 April 2008

Identification of protein domains on topological basis

scientific article published on 01 February 2001

Determination of phenolic antioxidants in aviation jet fuel

scientific article published on 01 February 2000

Aggregation propensity of Aib homo-peptides of different length: an insight from molecular dynamics simulations

scientific article published on 20 May 2014

3D structure, dynamics, and activity of synthetic analog of the peptaibiotic trichodecenin I.

scientific article published in May 2013

Determination of total and polycyclic aromatic hydrocarbons in aviation jet fuel

scientific article

Selectively targeting bacteria by tuning the molecular design of membrane-active peptidomimetic amphiphiles

scientific article published on 27 April 2018

Molecular Dynamics Simulations of the Host Defense Peptide Temporin L and Its Q3K Derivative: An Atomic Level View from Aggregation in Water to Bilayer Perturbation

scientific article published on 22 July 2017

Sound-driven dissipative self-assembly of aromatic biomolecules into functional nanoparticles

scientific article published on 01 March 2020

Rheoreversible hydrogels in paper restoration processes: a versatile tool

scientific article published on 10 February 2014

Monitoring peptide folding by time-resolved spectroscopies: the effect of a single Gly to Aib substitution.

scientific article published in January 2009

Aggregation propensity of therapeutic fibrin-homing pentapeptides: insights from experiments and molecular dynamics simulations

scientific article published on 09 November 2020

Receptors for organochlorine pesticides based on calixarenes

Orienting proteins by nanostructured surfaces: evidence of a curvature-driven geometrical resonance.

scientific article published on 11 April 2018

Antimicrobial peptides chelating lanthanide ions: the case of trichogin GA IV analogues and terbium(III)

scientific article published on 01 January 2009

List of works by Gianfranco Bocchinfuso

Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease

Germline missense mutations affecting KRAS Isoform B are associated with a severe Noonan syndrome phenotype

Mutations in KCNH1 and ATP6V1B2 cause Zimmermann-Laband syndrome.

Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis

Dual role of DNA intrinsic curvature and flexibility in determining nucleosome stability

Mutations in ZBTB20 cause Primrose syndrome

Diverse driving forces underlie the invariant occurrence of the T42A, E139D, I282V and T468M SHP2 amino acid substitutions causing Noonan and LEOPARD syndromes

Mutations Impairing GSK3-Mediated MAF Phosphorylation Cause Cataract, Deafness, Intellectual Disability, Seizures, and a Down Syndrome-like Facies

Activating Mutations Affecting the Dbl Homology Domain of SOS2 Cause Noonan Syndrome

Different mechanisms of action of antimicrobial peptides: insights from fluorescence spectroscopy experiments and molecular dynamics simulations.

A restricted spectrum of mutations in the SMAD4 tumor-suppressor gene underlies Myhre syndrome

Membrane thickness and the mechanism of action of the short peptaibol trichogin GA IV

Membrane perturbation by the antimicrobial peptide PMAP-23: a fluorescence and molecular dynamics study

Fluorescence spectroscopy and molecular dynamics simulations in studies on the mechanism of membrane destabilization by antimicrobial peptides.

A new polysaccharidic gel matrix for drug delivery: preparation and mechanical properties

A new scleroglucan/borax hydrogel: swelling and drug release studies.

Structural and functional effects of disease-causing amino acid substitutions affecting residues Ala72 and Glu76 of the protein tyrosine phosphatase SHP-2

Investigation on a new scleroglucan/borax hydrogel: structure and drug release

Metal binding properties of fluorescent analogues of trichogin GA IV: a conformational study by time-resolved spectroscopy and molecular mechanics investigations.

The importance of being kinked: role of Pro residues in the selectivity of the helical antimicrobial peptide P5.

Structural, Functional, and Clinical Characterization of a Novel PTPN11 Mutation Cluster Underlying Noonan Syndrome

Novel SMAD4 mutation causing Myhre syndrome

Dynamics of formation of a helix-turn-helix structure in a membrane-active peptide: a time-resolved spectroscopic study

Guar gum and scleroglucan interactions with borax: experimental and theoretical studies of an unexpected similarity.

Counteracting effects operating on Src homology 2 domain-containing protein-tyrosine phosphatase 2 (SHP2) function drive selection of the recurrent Y62D and Y63C substitutions in Noonan syndrome

Molecular dynamics methods to predict peptide locations in membranes: LAH4 as a stringent test case.

Molecular dynamics investigations of the polysaccharide scleroglucan: first study on the triple helix structure

Fibrils or globules? Tuning the morphology of peptide aggregates from helical building blocks.

Peptide folding dynamics: a time-resolved study from the nanosecond to the microsecond time regime

Versatile hydrogels: an efficient way to clean paper artworks

Photophysical properties of 1,3,5-tris(2-naphthyl)benzene and related less-arylated compounds: experimental and theoretical investigations

Theoretical and experimental study on a self-assembling polysaccharide forming nanochannels: static and dynamic effects induced by a soft confinement

Identification of protein domains on topological basis

Determination of phenolic antioxidants in aviation jet fuel

Aggregation propensity of Aib homo-peptides of different length: an insight from molecular dynamics simulations

3D structure, dynamics, and activity of synthetic analog of the peptaibiotic trichodecenin I.

Determination of total and polycyclic aromatic hydrocarbons in aviation jet fuel

Selectively targeting bacteria by tuning the molecular design of membrane-active peptidomimetic amphiphiles

Molecular Dynamics Simulations of the Host Defense Peptide Temporin L and Its Q3K Derivative: An Atomic Level View from Aggregation in Water to Bilayer Perturbation

Sound-driven dissipative self-assembly of aromatic biomolecules into functional nanoparticles

Rheoreversible hydrogels in paper restoration processes: a versatile tool

Monitoring peptide folding by time-resolved spectroscopies: the effect of a single Gly to Aib substitution.

Aggregation propensity of therapeutic fibrin-homing pentapeptides: insights from experiments and molecular dynamics simulations

Receptors for organochlorine pesticides based on calixarenes

Orienting proteins by nanostructured surfaces: evidence of a curvature-driven geometrical resonance.

Antimicrobial peptides chelating lanthanide ions: the case of trichogin GA IV analogues and terbium(III)