List of works - Mark Pfuhl

A calmodulin-binding sequence in the C-terminus of human cardiac titin kinase

scientific article

A structural and functional dissection of the cardiac stress response factor MS1

article

An undecided coiled coil: the leucine zipper of Nek2 kinase exhibits atypical conformational exchange dynamics

scientific article

Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly

scientific article

Controlling the dynamics of the Nek2 leucine zipper by engineering of "kinetic" disulphide bonds

scientific article published on 01 February 2019

Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding

scientific article

Correlation Between Conformational and Binding Properties of Nebulin Repeats

Dissecting the N-terminal myosin binding site of human cardiac myosin-binding protein C. Structure and myosin binding of domain C2

scientific article

East Coast fever, a neglected tropical disease with an outdated vaccine approach?

scientific article published in 2022

Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase

scientific article published on 13 December 2019

Halide and proton binding kinetics of yellow fluorescent protein variants

scientific article published on 2 April 2013

Immunoglobulin-type domains of titin: same fold, different stability?

scientific article

Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins

scientific article

Making ends meet: the importance of the N- and C-termini for the structure, stability, and function of the third SH3 domain of CIN85.

scientific article

Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic α-helix ⬇️

scientific article published on 6 March 2018

Molecular mechanism of the calcium-induced conformational change in the spectrin EF-hands.

scientific article

Myosin Binding Protein C Positioned to Play a Key Role in Regulation of Muscle Contraction: Structure and Interactions of Domain C1

scientific article

NMR analysis of the N-terminal SRCR domain of human CD5: engineering of a glycoprotein for superior characteristics in NMR experiments

scientific article

Novel insights into the mechanisms of CIN85 SH3 domains binding to Cbl proteins: solution-based investigations and in vivo implications

scientific article

On the Ca2+ binding and conformational change in EF-hand domains: Experimental evidence of Ca2+-saturated intermediates of N-domain of calmodulin.

scientific article published on 10 March 2017

Secondary structure determination by NMR spectroscopy of an immunoglobulin-like domain from the giant muscle protein titin ⬇️

scientific article published on July 1, 1995

Sequence specific 1H, 13C and 15N resonance assignment of rat CD2 domain 1

article

Sequence specific assignment of domain C1 of the N-terminal myosin-binding site of human cardiac myosin binding protein C (MyBP-C).

scientific article

Sequence specific resonance assignment of the central domain of cardiac myosin binding protein C (MyBP-C)

scientific article published on 01 February 2002

Solution NMR assignment of the ARC4 domain of human tankyrase 2

scientific article published on 07 March 2019

Solution NMR assignment of the C-terminal domain of human chTOG. ⬇️

scientific article published on 26 March 2018

Solution NMR assignment of the cryptic sixth TOG domain of mini spindles

scientific article published on 14 May 2015

Solution NMR assignment of the heavy chain complex of the human cardiac myosin regulatory light chain

scientific article published on 12 January 2014

Solution structure of the spectrin repeat: a left-handed antiparallel triple-helical coiled-coil

scientific article

Structural characterization of the N-terminal oligomerization domain of the bacterial chromatin-structuring protein, H-NS.

scientific article

Structure and interactions of myosin-binding protein C domain C0: cardiac-specific regulation of myosin at its neck?

scientific article published on 5 February 2011

Structure, interactions and function of the N-terminus of cardiac myosin binding protein C (MyBP-C): who does what, with what, and to whom?

scientific article published on 20 April 2012

Structure, stability and dynamics of the central domain of cardiac myosin binding protein C (MyBP-C): implications for multidomain assembly and causes for cardiomyopathy

scientific article (publication date: 13 June 2003)

Tertiary structure of an immunoglobulin-like domain from the giant muscle protein titin: a new member of the I set

scientific article

The Cardiac Stress Response Factor Ms1 Can Bind to DNA and Has a Function in the Nucleus

scientific article published on 14 December 2015

The binding stoichiometry of CIN85 SH3 domain A and cbl-b

scientific article published on September 2008

The calponin regulatory region is intrinsically unstructured: novel insight into actin-calponin and calmodulin-calponin interfaces using NMR spectroscopy

scientific article published on April 2011

The pH dependence of CD2 domain 1 self-association and 15N chemical exchange broadening is correlated with the anomalous pKa of Glu41.

scientific article published in December 2002

The spectrin repeat folds into a three-helix bundle in solution.

scientific article published in April 1996

When a module is also a domain: the rôle of the N terminus in the stability and the dynamics of immunoglobulin domains from titin

scientific article

When a module is not a domain: the case of the REJ module and the redefinition of the architecture of polycystin-1.

scientific article published on May 2011

List of works by Mark Pfuhl

A calmodulin-binding sequence in the C-terminus of human cardiac titin kinase

A structural and functional dissection of the cardiac stress response factor MS1

An undecided coiled coil: the leucine zipper of Nek2 kinase exhibits atypical conformational exchange dynamics

Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly

Controlling the dynamics of the Nek2 leucine zipper by engineering of "kinetic" disulphide bonds

Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding

Correlation Between Conformational and Binding Properties of Nebulin Repeats

Dissecting the N-terminal myosin binding site of human cardiac myosin-binding protein C. Structure and myosin binding of domain C2

East Coast fever, a neglected tropical disease with an outdated vaccine approach?

Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase

Halide and proton binding kinetics of yellow fluorescent protein variants

Immunoglobulin-type domains of titin: same fold, different stability?

Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins

Making ends meet: the importance of the N- and C-termini for the structure, stability, and function of the third SH3 domain of CIN85.

Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic α-helix ⬇️

Molecular mechanism of the calcium-induced conformational change in the spectrin EF-hands.

Myosin Binding Protein C Positioned to Play a Key Role in Regulation of Muscle Contraction: Structure and Interactions of Domain C1

NMR analysis of the N-terminal SRCR domain of human CD5: engineering of a glycoprotein for superior characteristics in NMR experiments

Novel insights into the mechanisms of CIN85 SH3 domains binding to Cbl proteins: solution-based investigations and in vivo implications

On the Ca2+ binding and conformational change in EF-hand domains: Experimental evidence of Ca2+-saturated intermediates of N-domain of calmodulin.

Secondary structure determination by NMR spectroscopy of an immunoglobulin-like domain from the giant muscle protein titin ⬇️

Sequence specific 1H, 13C and 15N resonance assignment of rat CD2 domain 1

Sequence specific assignment of domain C1 of the N-terminal myosin-binding site of human cardiac myosin binding protein C (MyBP-C).

Sequence specific resonance assignment of the central domain of cardiac myosin binding protein C (MyBP-C)

Solution NMR assignment of the ARC4 domain of human tankyrase 2

Solution NMR assignment of the C-terminal domain of human chTOG. ⬇️

Solution NMR assignment of the cryptic sixth TOG domain of mini spindles

Solution NMR assignment of the heavy chain complex of the human cardiac myosin regulatory light chain

Solution structure of the spectrin repeat: a left-handed antiparallel triple-helical coiled-coil

Structural characterization of the N-terminal oligomerization domain of the bacterial chromatin-structuring protein, H-NS.

Structure and interactions of myosin-binding protein C domain C0: cardiac-specific regulation of myosin at its neck?

Structure, interactions and function of the N-terminus of cardiac myosin binding protein C (MyBP-C): who does what, with what, and to whom?

Structure, stability and dynamics of the central domain of cardiac myosin binding protein C (MyBP-C): implications for multidomain assembly and causes for cardiomyopathy

Tertiary structure of an immunoglobulin-like domain from the giant muscle protein titin: a new member of the I set

The Cardiac Stress Response Factor Ms1 Can Bind to DNA and Has a Function in the Nucleus

The binding stoichiometry of CIN85 SH3 domain A and cbl-b

The calponin regulatory region is intrinsically unstructured: novel insight into actin-calponin and calmodulin-calponin interfaces using NMR spectroscopy

The pH dependence of CD2 domain 1 self-association and 15N chemical exchange broadening is correlated with the anomalous pKa of Glu41.

The spectrin repeat folds into a three-helix bundle in solution.

When a module is also a domain: the rôle of the N terminus in the stability and the dynamics of immunoglobulin domains from titin

When a module is not a domain: the case of the REJ module and the redefinition of the architecture of polycystin-1.