List of works - Volkhard Helms

The Mechanism of Proton Exclusion in the Aquaporin-1 Water Channel

scientific article published on 01 October 2003

Shedding light on the dark and weakly fluorescent states of green fluorescent proteins

scientific article published on May 1999

Transient Pockets on Protein Surfaces Involved in Protein−Protein Interaction

Protein translocation across the ER membrane

scientific article published on 27 June 2010

Diffusional encounter of barnase and barstar

scientific article published on 16 December 2005

BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER

scientific article

Adhesive water networks facilitate binding of protein interfaces

scientific article published in Nature Communications

A STIM2 splice variant negatively regulates store-operated calcium entry.

scientific article published on 21 April 2015

Interaction of calmodulin with Sec61α limits Ca2+ leakage from the endoplasmic reticulum

scientific article

Dynamic water networks in cytochrome C oxidase from Paracoccus denitrificans investigated by molecular dynamics simulations

scientific article published on April 2004

Mechanism of fast peptide recognition by SH3 domains

scientific article

Proton shuttle in green fluorescent protein studied by dynamic simulations

scientific article

Thermodynamics of water mediating protein-ligand interactions in cytochrome P450cam: a molecular dynamics study

scientific article published on September 1995

Protein transport into the human endoplasmic reticulum

scientific article published on 23 June 2014

Cyclophilin A binds to linear peptide motifs containing a consensus that is present in many human proteins

scientific article published on 21 April 2005

Statistical analysis of predominantly transient protein-protein interfaces

article

Tandem repeats in the CpG islands of imprinted genes

article

Protein Dynamics Tightly Connected to the Dynamics of Surrounding and Internal Water Molecules

article

What induces pocket openings on protein surface patches involved in protein-protein interactions?

scientific article

Improved Binding of Cytochrome P450cam Substrate Analogues Designed To Fill Extra Space in the Substrate Binding Pocket†

article

Molecular dynamics simulation of proton transport with quantum mechanically derived proton hopping rates (Q-HOP MD)

article

Conserved gating elements in TRPC4 and TRPC5 channels

scientific article published on 15 May 2013

Transport of soluble proteins through the Golgi occurs by diffusion via continuities across cisternae

scientific article

TFmiR: a web server for constructing and analyzing disease-specific transcription factor and miRNA co-regulatory networks

scientific article published on 5 May 2015

Interfering with Bacterial Quorum Sensing

scientific article published on 18 January 2016

Determinants of ligand binding to cAMP-dependent protein kinase.

scientific article published on February 1999

IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype.

scientific article

A structural model of the complex formed by phospholamban and the calcium pump of sarcoplasmic reticulum obtained by molecular mechanics

scientific article published in December 2002

Integrative network-based approach identifies key genetic elements in breast invasive carcinoma

scientific article published on 26 May 2015

Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma

scientific article published on 4 April 2014

Detecting Staphylococcus aureus Virulence and Resistance Genes: a Comparison of Whole-Genome Sequencing and DNA Microarray Technology

scientific article published on 27 January 2016

Hydration energy landscape of the active site cavity in cytochrome P450cam

scientific article published on 01 August 1998

Prediction of the burial status of transmembrane residues of helical membrane proteins

scientific article

Structural changes in cytochrome P-450cam effected by the binding of the enantiomers (1R)-camphor and (1S)-camphor.

scientific article

Free Energy Landscape of Protein-Protein Encounter Resulting from Brownian Dynamics Simulations of Barnase:Barstar

scientific article published in July 2005

A spatial model of the chromatophore vesicles of Rhodobacter sphaeroides and the position of the Cytochrome bc1 complex

scientific article published on 19 May 2006

AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum

scientific article published in Nature Communications

Low-lying electronic excitations of the green fluorescent protein chromophore

Titration behavior of residues at the entrance of the D-pathway of cytochrome c oxidase from paracoccus denitrificans investigated by continuum electrostatic calculations

scientific article published on October 2005

Computational Alchemy To Calculate Absolute Protein−Ligand Binding Free Energy

scientific article published in 1998

DNA co-methylation analysis suggests novel functional associations between gene pairs in breast cancer samples

scientific article published on 09 April 2013

TMBHMM: a frequency profile based HMM for predicting the topology of transmembrane beta barrel proteins and the exposure status of transmembrane residues

scientific article

Atomistic simulation of water percolation and proton hopping in Nafion fuel cell membrane

scientific article published in November 2010

Imprinted genes show unique patterns of sequence conservation

scientific article

Matched-cohort DNA microarray diversity analysis of methicillin sensitive and methicillin resistant Staphylococcus aureus isolates from hospital admission patients

scientific article

Specific and non-specific effects of potassium cations on substrate-protein interactions in cytochromes P450cam and P450lin

scientific article published in September 2002

Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma

scientific article published on 06 July 2016

Reconstruction of a kinetic model of the chromatophore vesicles from Rhodobacter sphaeroides

scientific article published on 19 May 2006

Electronic excitations of biomolecules studied by quantum chemistry

scientific article

Hepatic hepcidin expression is decreased in cirrhosis and HCC

scientific article published on 21 November 2014

List of works by Volkhard Helms

The Mechanism of Proton Exclusion in the Aquaporin-1 Water Channel

Shedding light on the dark and weakly fluorescent states of green fluorescent proteins

Transient Pockets on Protein Surfaces Involved in Protein−Protein Interaction

Protein translocation across the ER membrane

Diffusional encounter of barnase and barstar

BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER

Adhesive water networks facilitate binding of protein interfaces

A STIM2 splice variant negatively regulates store-operated calcium entry.

Interaction of calmodulin with Sec61α limits Ca2+ leakage from the endoplasmic reticulum

Dynamic water networks in cytochrome C oxidase from Paracoccus denitrificans investigated by molecular dynamics simulations

Mechanism of fast peptide recognition by SH3 domains

Proton shuttle in green fluorescent protein studied by dynamic simulations

Thermodynamics of water mediating protein-ligand interactions in cytochrome P450cam: a molecular dynamics study

Protein transport into the human endoplasmic reticulum

Cyclophilin A binds to linear peptide motifs containing a consensus that is present in many human proteins

Statistical analysis of predominantly transient protein-protein interfaces

Tandem repeats in the CpG islands of imprinted genes

Protein Dynamics Tightly Connected to the Dynamics of Surrounding and Internal Water Molecules

What induces pocket openings on protein surface patches involved in protein-protein interactions?

Improved Binding of Cytochrome P450cam Substrate Analogues Designed To Fill Extra Space in the Substrate Binding Pocket†

Molecular dynamics simulation of proton transport with quantum mechanically derived proton hopping rates (Q-HOP MD)

Conserved gating elements in TRPC4 and TRPC5 channels

Transport of soluble proteins through the Golgi occurs by diffusion via continuities across cisternae

TFmiR: a web server for constructing and analyzing disease-specific transcription factor and miRNA co-regulatory networks

Interfering with Bacterial Quorum Sensing

Determinants of ligand binding to cAMP-dependent protein kinase.

IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype.

A structural model of the complex formed by phospholamban and the calcium pump of sarcoplasmic reticulum obtained by molecular mechanics

Integrative network-based approach identifies key genetic elements in breast invasive carcinoma

Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma

Detecting Staphylococcus aureus Virulence and Resistance Genes: a Comparison of Whole-Genome Sequencing and DNA Microarray Technology

Hydration energy landscape of the active site cavity in cytochrome P450cam

Prediction of the burial status of transmembrane residues of helical membrane proteins

Structural changes in cytochrome P-450cam effected by the binding of the enantiomers (1R)-camphor and (1S)-camphor.

Free Energy Landscape of Protein-Protein Encounter Resulting from Brownian Dynamics Simulations of Barnase:Barstar

A spatial model of the chromatophore vesicles of Rhodobacter sphaeroides and the position of the Cytochrome bc1 complex

AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum

Low-lying electronic excitations of the green fluorescent protein chromophore

Titration behavior of residues at the entrance of the D-pathway of cytochrome c oxidase from paracoccus denitrificans investigated by continuum electrostatic calculations

Computational Alchemy To Calculate Absolute Protein−Ligand Binding Free Energy

DNA co-methylation analysis suggests novel functional associations between gene pairs in breast cancer samples

TMBHMM: a frequency profile based HMM for predicting the topology of transmembrane beta barrel proteins and the exposure status of transmembrane residues

Atomistic simulation of water percolation and proton hopping in Nafion fuel cell membrane

Imprinted genes show unique patterns of sequence conservation

Matched-cohort DNA microarray diversity analysis of methicillin sensitive and methicillin resistant Staphylococcus aureus isolates from hospital admission patients

Specific and non-specific effects of potassium cations on substrate-protein interactions in cytochromes P450cam and P450lin

Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma

Reconstruction of a kinetic model of the chromatophore vesicles from Rhodobacter sphaeroides

Electronic excitations of biomolecules studied by quantum chemistry

Hepatic hepcidin expression is decreased in cirrhosis and HCC