List of works - Doron Rapaport

A crucial role for Mim2 in the biogenesis of mitochondrial outer membrane proteins

scientific article

A novel heterozygous OPA3 mutation located in the mitochondrial target sequence results in altered steady-state levels and fragmented mitochondrial network

scientific article published on 17 October 2013

Absence of BiP Co-chaperone DNAJC3 Causes Diabetes Mellitus and Multisystemic Neurodegeneration

Absence of BiP co-chaperone DNAJC3 causes diabetes mellitus and multisystemic neurodegeneration

scientific article

Alterations in expression levels of deafness dystonia protein 1 affect mitochondrial morphology ⬇️

scientific article published on October 7, 2011

Alternative splicing gives rise to different isoforms of the Neurospora crassa Tob55 protein that vary in their ability to insert beta-barrel proteins into the outer mitochondrial membrane

scientific article

An Essential Role for COPI in mRNA Localization to Mitochondria and Mitochondrial Function

scientific article published on 7 April 2016

An assay to monitor the membrane integration of single-span proteins

scientific article published in January 2013

Analysis and prediction of mitochondrial targeting signals

scientific article published on January 2007

Analyzing import intermediates of mitochondrial proteins by blue native gel electrophoresis

scientific article published in January 2007

Assembly of the TOB complex of mitochondria

scientific article

Association of Bcl-2 with misfolded prion protein is linked to the toxic potential of cytosolic PrP.

scientific article published on 17 May 2006

Biogenesis of Tom40, core component of the TOM complex of mitochondria

scientific article published on July 1999

Biogenesis of beta-barrel membrane proteins in bacteria and eukaryotes: evolutionary conservation and divergence

scientific article

Biogenesis of beta-barrel membrane proteins of mitochondria

scientific article

Biogenesis of beta-barrel proteins in evolutionary context

scientific article

Biogenesis of mitochondrial outer membrane proteins

scientific article published on 03 May 2008

Biogenesis of porin of the outer mitochondrial membrane involves an import pathway via receptors and the general import pore of the TOM complex

scientific article published on January 2001

Biogenesis of the mitochondrial TOM complex

scientific article

Biogenesis pathways of α-helical mitochondrial outer membrane proteins

scientific article published on 18 February 2020

Characterization of the targeting signal in mitochondrial β-barrel proteins

scientific article

Chloroplast β-Barrel Proteins Are Assembled into the Mitochondrial Outer Membrane in a Process That Depends on the TOM and TOB Complexes ⬇️

scientific article published on June 28, 2012

Coi1 is a novel assembly factor of the yeast complex III-complex IV supercomplex

scientific article published on 9 August 2017

Connection of the mitochondrial outer and inner membranes by Fzo1 is critical for organellar fusion

scientific article

Cytosolic Hsp70 and Hsp40 chaperones enable the biogenesis of mitochondrial β-barrel proteins

scientific article published on 21 June 2018

Das Deutsche Netzwerk für mitochondriale Erkrankungen (mitoNET)

Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis

scientific article published on 2 September 2010

Dynamics of the TOM Complex of Mitochondria during Binding and Translocation of Preproteins ⬇️

scientific article published on September 1, 1998

Early stages in the biogenesis of eukaryotic β-barrel proteins

scientific article

Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes

scientific article

Evolutionary conservation in biogenesis of β-barrel proteins allows mitochondria to assemble a functional bacterial trimeric autotransporter protein

scientific article

Evolutionary conservation of biogenesis of beta-barrel membrane proteins

scientific article

Finding the right organelle. Targeting signals in mitochondrial outer-membrane proteins

scientific article published on October 2003

Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiae

scientific article

Genetic and functional interactions between the mitochondrial outer membrane proteins Tom6 and Sam37.

scientific article

Genome-Wide Screens in Saccharomyces cerevisiae Highlight a Role for Cardiolipin in Biogenesis of Mitochondrial Outer Membrane Multispan Proteins

scientific article

How does the TOM complex mediate insertion of precursor proteins into the mitochondrial outer membrane?

scientific article

Independent evolution of functionally exchangeable mitochondrial outer membrane import complexes.

scientific article published on 20 June 2018

Integration of tail-anchored proteins into the mitochondrial outer membrane does not require any known import components

scientific article

Mcp1 and Mcp2, two novel proteins involved in mitochondrial lipid homeostasis

scientific article

Mcp3 is a novel mitochondrial outer membrane protein that follows a unique IMP-dependent biogenesis pathway

scientific article

Mcp3 is a novel mitochondrial outer membrane protein that follows a unique IMP-dependent biogenesis pathway.

scientific article

Membrane integration of a mitochondrial signal-anchored protein does not require additional proteinaceous factors

article published in 2012

Mim1 functions in an oligomeric form to facilitate the integration of Tom20 into the mitochondrial outer membrane

scientific article published on 8 December 2007

Mim1, a protein required for the assembly of the TOM complex of mitochondria

scientific article

Mitochondria can recognize and assemble fragments of a β-barrel structure ⬇️

scientific article published on May 15, 2011

Mitochondrial contact sites as platforms for phospholipid exchange

scientific article

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2.

scientific article published on 24 November 2015

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2.

scientific article published on 27 December 2016

Mitochondrial protein import. Tom40 plays a major role in targeting and translocation of preproteins by forming a specific binding site for the presequence

scientific article published on 01 July 1997

Mitochondrial protein import: recognition of internal import signals of BCS1 by the TOM complex

scientific article

Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1.

scientific article published on 17 April 2014

Mitochondrial-bacterial hybrids of BamA/Tob55 suggest variable requirements for the membrane integration of β-barrel proteins

scientific article

Mitochondrion-enriched anionic phospholipids facilitate flock house virus RNA polymerase membrane association

scientific article published on 25 February 2009

Multiple pathways in the integration of proteins into the mitochondrial outer membrane

scientific article published on 30 June 2010

Multispan mitochondrial outer membrane protein Ugo1 follows a unique Mim1-dependent import pathway ⬇️

scientific article published on August 8, 2011

Neurospora crassa as a model organism for mitochondrial biogenesis

scientific article published in January 2007

New insights into the mechanism of precursor protein insertion into the mitochondrial membranes

scientific article published on January 2008

Pex19 is involved in importing dually targeted tail-anchored proteins to both mitochondria and peroxisomes

scientific article published on 14 August 2018

Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging

scientific article

Proteome analysis of mitochondrial outer membrane from Neurospora crassa

scientific article published in January 2006

Proteomic view of mitochondrial function

scientific article published on 29 February 2008

Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes

scientific article

Role of the Negative Charges in the Cytosolic Domain of TOM22 in the Import of Precursor Proteins into Mitochondria ⬇️

scientific article published on June 1, 1998

Signal-anchored proteins follow a unique insertion pathway into the outer membrane of mitochondria

scientific article

Signals in bacterial beta-barrel proteins are functional in eukaryotic cells for targeting to and assembly in mitochondria

scientific article

Structural basis of client specificity in mitochondrial membrane-protein chaperones

scientific article published on 18 December 2020

Structural requirements of Tom40 for assembly into preexisting TOM complexes of mitochondria

scientific article published on May 2001

The C-terminal domain of Fcj1 is required for formation of crista junctions and interacts with the TOB/SAM complex in mitochondria

scientific article

The Endoplasmic Reticulum-Mitochondria Encounter Structure Complex Coordinates Coenzyme Q Biosynthesis

The GET pathway can increase the risk of mitochondrial outer membrane proteins to be mistargeted to the ER

scientific article published on 16 May 2018

The Mitochondrial Protein OM45 Is Exposed to the Cytosol ⬇️

scientific article published on August 10, 2012

The N-terminal domain of Tob55 has a receptor-like function in the biogenesis of mitochondrial beta-barrel proteins

scientific article

The cytosolic cochaperone Sti1 is relevant for mitochondrial biogenesis and morphology

scientific article

The enigmatic role of Mim1 in mitochondrial biogenesis

scientific article

The mitochondrial TOM complex is required for tBid/Bax-induced cytochrome c release

scientific article

The mitochondrial porin, VDAC, has retained the ability to be assembled in the bacterial outer membrane

scientific article

The quest for a better resolution of protein-translocation processes. Conference on the Control, Co-ordination and Regulation of Protein Targeting and Translocation

scientific article published on 20 March 2009

The role of Djp1 in import of the mitochondrial protein Mim1 demonstrates specificity between a cochaperone and its substrate protein

scientific article

Tob38, a novel essential component in the biogenesis of beta-barrel proteins of mitochondria

scientific article

Tom20 mediates localization of mRNAs to mitochondria in a translation-dependent manner

scientific article

Tom70 is essential for PINK1 import into mitochondria

scientific article

Unresolved mysteries in the biogenesis of mitochondrial membrane proteins ⬇️

scientific article published on August 27, 2011

Yeast Mitochondria as a Model System to Study the Biogenesis of Bacterial β-Barrel Proteins

scientific article published on January 2015

Yeast phospholipid biosynthesis is linked to mRNA localization

scientific article published in 2014

cis and trans Sites of the TOM Complex of Mitochondria in Unfolding and Initial Translocation of Preproteins ⬇️

scientific article published on April 10, 1998

List of works by Doron Rapaport

A crucial role for Mim2 in the biogenesis of mitochondrial outer membrane proteins

A novel heterozygous OPA3 mutation located in the mitochondrial target sequence results in altered steady-state levels and fragmented mitochondrial network

Absence of BiP Co-chaperone DNAJC3 Causes Diabetes Mellitus and Multisystemic Neurodegeneration

Absence of BiP co-chaperone DNAJC3 causes diabetes mellitus and multisystemic neurodegeneration

Alterations in expression levels of deafness dystonia protein 1 affect mitochondrial morphology ⬇️

Alternative splicing gives rise to different isoforms of the Neurospora crassa Tob55 protein that vary in their ability to insert beta-barrel proteins into the outer mitochondrial membrane

An Essential Role for COPI in mRNA Localization to Mitochondria and Mitochondrial Function

An assay to monitor the membrane integration of single-span proteins

Analysis and prediction of mitochondrial targeting signals

Analyzing import intermediates of mitochondrial proteins by blue native gel electrophoresis

Assembly of the TOB complex of mitochondria

Association of Bcl-2 with misfolded prion protein is linked to the toxic potential of cytosolic PrP.

Biogenesis of Tom40, core component of the TOM complex of mitochondria

Biogenesis of beta-barrel membrane proteins in bacteria and eukaryotes: evolutionary conservation and divergence

Biogenesis of beta-barrel membrane proteins of mitochondria

Biogenesis of beta-barrel proteins in evolutionary context

Biogenesis of mitochondrial outer membrane proteins

Biogenesis of porin of the outer mitochondrial membrane involves an import pathway via receptors and the general import pore of the TOM complex

Biogenesis of the mitochondrial TOM complex

Biogenesis pathways of α-helical mitochondrial outer membrane proteins

Characterization of the targeting signal in mitochondrial β-barrel proteins

Chloroplast β-Barrel Proteins Are Assembled into the Mitochondrial Outer Membrane in a Process That Depends on the TOM and TOB Complexes ⬇️

Coi1 is a novel assembly factor of the yeast complex III-complex IV supercomplex

Connection of the mitochondrial outer and inner membranes by Fzo1 is critical for organellar fusion

Cytosolic Hsp70 and Hsp40 chaperones enable the biogenesis of mitochondrial β-barrel proteins

Das Deutsche Netzwerk für mitochondriale Erkrankungen (mitoNET)

Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of disease-related variants on mitochondrial homeostasis

Dynamics of the TOM Complex of Mitochondria during Binding and Translocation of Preproteins ⬇️

Early stages in the biogenesis of eukaryotic β-barrel proteins

Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes

Evolutionary conservation in biogenesis of β-barrel proteins allows mitochondria to assemble a functional bacterial trimeric autotransporter protein

Evolutionary conservation of biogenesis of beta-barrel membrane proteins

Finding the right organelle. Targeting signals in mitochondrial outer-membrane proteins

Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiae

Genetic and functional interactions between the mitochondrial outer membrane proteins Tom6 and Sam37.

Genome-Wide Screens in Saccharomyces cerevisiae Highlight a Role for Cardiolipin in Biogenesis of Mitochondrial Outer Membrane Multispan Proteins

How does the TOM complex mediate insertion of precursor proteins into the mitochondrial outer membrane?

Independent evolution of functionally exchangeable mitochondrial outer membrane import complexes.

Integration of tail-anchored proteins into the mitochondrial outer membrane does not require any known import components

Mcp1 and Mcp2, two novel proteins involved in mitochondrial lipid homeostasis

Mcp3 is a novel mitochondrial outer membrane protein that follows a unique IMP-dependent biogenesis pathway

Mcp3 is a novel mitochondrial outer membrane protein that follows a unique IMP-dependent biogenesis pathway.

Membrane integration of a mitochondrial signal-anchored protein does not require additional proteinaceous factors

Mim1 functions in an oligomeric form to facilitate the integration of Tom20 into the mitochondrial outer membrane

Mim1, a protein required for the assembly of the TOM complex of mitochondria

Mitochondria can recognize and assemble fragments of a β-barrel structure ⬇️

Mitochondrial contact sites as platforms for phospholipid exchange

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2.

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2.

Mitochondrial protein import. Tom40 plays a major role in targeting and translocation of preproteins by forming a specific binding site for the presequence

Mitochondrial protein import: recognition of internal import signals of BCS1 by the TOM complex

Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1.

Mitochondrial-bacterial hybrids of BamA/Tob55 suggest variable requirements for the membrane integration of β-barrel proteins

Mitochondrion-enriched anionic phospholipids facilitate flock house virus RNA polymerase membrane association

Multiple pathways in the integration of proteins into the mitochondrial outer membrane

Multispan mitochondrial outer membrane protein Ugo1 follows a unique Mim1-dependent import pathway ⬇️

Neurospora crassa as a model organism for mitochondrial biogenesis

New insights into the mechanism of precursor protein insertion into the mitochondrial membranes

Pex19 is involved in importing dually targeted tail-anchored proteins to both mitochondria and peroxisomes

Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging

Proteome analysis of mitochondrial outer membrane from Neurospora crassa

Proteomic view of mitochondrial function

Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes

Role of the Negative Charges in the Cytosolic Domain of TOM22 in the Import of Precursor Proteins into Mitochondria ⬇️

Signal-anchored proteins follow a unique insertion pathway into the outer membrane of mitochondria

Signals in bacterial beta-barrel proteins are functional in eukaryotic cells for targeting to and assembly in mitochondria

Structural basis of client specificity in mitochondrial membrane-protein chaperones

Structural requirements of Tom40 for assembly into preexisting TOM complexes of mitochondria

The C-terminal domain of Fcj1 is required for formation of crista junctions and interacts with the TOB/SAM complex in mitochondria

The Endoplasmic Reticulum-Mitochondria Encounter Structure Complex Coordinates Coenzyme Q Biosynthesis

The GET pathway can increase the risk of mitochondrial outer membrane proteins to be mistargeted to the ER

The Mitochondrial Protein OM45 Is Exposed to the Cytosol ⬇️

The N-terminal domain of Tob55 has a receptor-like function in the biogenesis of mitochondrial beta-barrel proteins

The cytosolic cochaperone Sti1 is relevant for mitochondrial biogenesis and morphology

The enigmatic role of Mim1 in mitochondrial biogenesis

The mitochondrial TOM complex is required for tBid/Bax-induced cytochrome c release

The mitochondrial porin, VDAC, has retained the ability to be assembled in the bacterial outer membrane

The quest for a better resolution of protein-translocation processes. Conference on the Control, Co-ordination and Regulation of Protein Targeting and Translocation

The role of Djp1 in import of the mitochondrial protein Mim1 demonstrates specificity between a cochaperone and its substrate protein