List of works - Tino Krell

93 The interaction of shikimate kinase fromErwinia chrystanthemiwith substrates

scientific article published on 01 November 1997

Affinity-purification of Transferrin-binding protein B under nondenaturing conditions

scientific article published on 01 April 2002

Amino acid sensor conserved from bacteria to humans

scientific article published on 01 March 2022

An auxin controls bacterial antibiotics production

scientific article published on 01 November 2018

Analysis of solvent tolerance in Pseudomonas putida DOT-T1E based on its genome sequence and a collection of mutants

scientific article

Bacterial chemotaxis towards aromatic hydrocarbons in Pseudomonas

scientific article published on 23 May 2011

Bacterial sensor kinase TodS interacts with agonistic and antagonistic signals

scholarly article

Bacterial sensor kinases: diversity in the recognition of environmental signals

scientific article published on January 2010

Bioavailability of pollutants and chemotaxis

scientific article published on 13 September 2012

Biochemical and X-ray crystallographic studies on shikimate kinase: The important structural role of the P-loop lysine

scientific article

Biochemical and molecular characterization of the mitochondrial peroxiredoxin PsPrxII F from Pisum sativum

scientific article published on 7 August 2007

Catabolite repression of the TodS/TodT two-component system and effector-dependent transphosphorylation of TodT as the basis for toluene dioxygenase catabolic pathway control

scientific article published on 11 June 2010

Characterization of different strains of poliovirus and influenza virus by differential scanning calorimetry

scientific article published in June 2005

Characterization of molecular interactions using isothermal titration calorimetry.

scientific article published in January 2014

Chemoperception of Specific Amino Acids Controls Phytopathogenicity in Pseudomonas syringae pv. tomato

scientific article published on 01 October 2019

Chemoreceptor-based signal sensing

scientific article published on 11 January 2017

Chemoreceptors with C-terminal pentapeptides for CheR and CheB binding are abundant in bacteria that maintain host interactions

scientific article published on 16 July 2020

Chemotaxis of the Human Pathogen Pseudomonas aeruginosa to the Neurotransmitter Acetylcholine

scientific article published on 07 March 2022

Compartmentalized glucose metabolism in Pseudomonas putida is controlled by the PtxS repressor

scientific journal article

Complexity in efflux pump control: cross-regulation by the paralogues TtgV and TtgT.

scientific article published on 5 November 2007

Construction of a prototype two-component system from the phosphorelay system TodS/TodT.

scientific article published on 3 February 2012

Correlation between signal input and output in PctA and PctB amino acid chemoreceptor of Pseudomonas aeruginosa

scientific article

Crystal Structures of Multidrug Binding Protein TtgR in Complex with Antibiotics and Plant Antimicrobials

scientific article

Crystal structure of TtgV in complex with its DNA operator reveals a general model for cooperative DNA binding of tetrameric gene regulators

scientific article

Crystallization and crystallographic analysis of the ligand-binding domain of the Pseudomonas putida chemoreceptor McpS in complex with malate and succinate

scientific article

Crystallization and preliminary X-ray crystallographic analysis of shikimate kinase from Erwinia chrysanthemi.

scientific article

Degeneration of rat cholinergic basal forebrain neurons and reactive changes in nerve growth factor expression after chronic neurotoxic injury—I. Degeneration and plastic response of basal forebrain neurons ⬇️

scientific article published on April 1, 1995

Degeneration of rat cholinergic basal forebrain neurons and reactive changes in nerve growth factor expression after chronic neurotoxic injury—II. Reactive expression of the nerve growth factor gene in astrocytes ⬇️

scientific article published on April 1, 1995

Different Modes of Binding of Mono- and Biaromatic Effectors to the Transcriptional Regulator TTGV

scientific article published in Journal of Biological Chemistry

Disparate response to microoxia and nitrogen oxides of the Bradyrhizobium japonicum napEDABC, nirK and norCBQD denitrification genes

scientific article published on 3 February 2017

Diversity at its best: bacterial taxis.

scientific article

Effect of the β-propiolactone treatment on the adsorption and fusion of influenza A/Brisbane/59/2007 and A/New Caledonia/20/1999 virus H1N1 on a dimyristoylphosphatidylcholine/ganglioside GM3 mixed phospholipids monolayer at the air-water interface

scientific article published on 21 October 2011

Effector-repressor interactions, binding of a single effector molecule to the operator-bound TtgR homodimer mediates derepression.

scientific article published on 5 January 2006

Evidence for Pentapeptide-Dependent and Independent CheB Methylesterases

scientific article published on 11 November 2020

Evidence for chemoreceptors with bimodular ligand-binding regions harboring two signal-binding sites

scientific article

Evidence for the shikimate pathway in apicomplexan parasites.

scientific article published on June 1998

Exploring the (almost) unknown: archaeal two-component systems

scientific article published on 16 January 2018

Fructooligosacharides reduce Pseudomonas aeruginosa PAO1 pathogenicity through distinct mechanisms

scientific article published on 22 January 2014

Fructose 1-Phosphate Is the Preferred Effector of the Metabolic Regulator Cra of Pseudomonas putida

scientific article

Fructose 1-phosphate is the one and only physiological effector of the Cra (FruR) regulator of Pseudomonas putida.

scientific article published on 4 April 2014

Functional Annotation of Bacterial Signal Transduction Systems: Progress and Challenges

scientific article published on 26 November 2018

Genes encoding Cher-TPR fusion proteins are predominantly found in gene clusters encoding chemosensory pathways with alternative cellular functions.

scientific article

Genes for carbon metabolism and the ToxA virulence factor in Pseudomonas aeruginosa are regulated through molecular interactions of PtxR and PtxS

scientific journal article

Genome Sequence of Serratia marcescens MSU97, a Plant-Associated Bacterium That Makes Multiple Antibiotics

scientific article published on 2 March 2017

Genome Sequence of Serratia plymuthica A153, a Model Rhizobacterium for the Investigation of the Synthesis and Regulation of Haterumalides, Zeamine, and Andrimid.

scientific article published on 19 May 2016

GtrS and GltR form a two-component system: the central role of 2-ketogluconate in the expression of exotoxin A and glucose catabolic enzymes in Pseudomonas aeruginosa

scientific article published on 11 June 2014

HIV-1 gp41 and gp160 are hyperthermostable proteins in a mesophilic environment. Characterization of gp41 mutants.

scientific article

Hexameric oligomerization of mitochondrial peroxiredoxin PrxIIF and formation of an ultrahigh affinity complex with its electron donor thioredoxin Trx-o

scientific article published on 15 July 2008

Hierarchical binding of the TodT response regulator to its multiple recognition sites at the tod pathway operon promoter.

scientific article published on 8 December 2007

High specificity in CheR methyltransferase function: CheR2 of Pseudomonas putida is essential for chemotaxis, whereas CheR1 is involved in biofilm formation.

scientific article published on 15 May 2013

High-Affinity Chemotaxis to Histamine Mediated by the TlpQ Chemoreceptor of the Human Pathogen Pseudomonas aeruginosa

scientific article published on 13 November 2018

How Bacterial Chemoreceptors Evolve Novel Ligand Specificities

scientific article published on 21 January 2020

Identification and purification of a distinct dihydrolipoamide dehydrogenase from pea chloroplasts

scientific article published on 01 January 1996

Identification of a Chemoreceptor for C2 and C3 Carboxylic Acids

scientific article published on 5 June 2015

Identification of a chemoreceptor for tricarboxylic acid cycle intermediates: differential chemotactic response towards receptor ligands

scientific article published on 24 May 2010

Identification of a chemoreceptor that specifically mediates chemotaxis toward metabolizable purine derivatives

scientific article published on 10 September 2015

Identification of a novel calcium binding motif based on the detection of sequence insertions in the animal peroxidase domain of bacterial proteins

scientific article

Identification of ligands for bacterial sensor proteins

scientific article

Identification of new residues involved in intramolecular signal transmission in a prokaryotic transcriptional repressor.

scientific article published on 15 November 2013

In situ X-ray data collection from highly sensitive crystals of Pseudomonas putida PtxS in complex with DNA.

scientific article

Insight into the structure and function of the transferrin receptor from Neisseria meningitidis using microcalorimetric techniques

scientific article published on 05 February 2003

Intramolecular signal transmission in a tetrameric repressor of the IclR family

scientific article

Is it possible to predict signal molecules that are recognized by bacterial receptors?

scientific article published in 2022

Laboratory research aimed at closing the gaps in microbial bioremediation

scientific article published on 18 July 2011

Localization of the Active Site of Type II Dehydroquinases

scientific article published in Journal of Biological Chemistry

McpQ is a specific citrate chemoreceptor that responds preferentially to citrate/metal ion complexes.

scientific article published on 14 October 2015

Members of the IclR family of bacterial transcriptional regulators function as activators and/or repressors

scientific article

Microcalorimetry: a response to challenges in modern biotechnology.

scientific article published on March 2008

Multiple signals modulate the activity of the complex sensor kinase TodS.

scientific article

Optimization of the palindromic order of the TtgR operator enhances binding cooperativity

scientific article

Paralogous Regulators ArsR1 and ArsR2 of Pseudomonas putida KT2440 as a Basis for Arsenic Biosensor Development

scientific article

Paralogous chemoreceptors mediate chemotaxis towards protein amino acids and the non-protein amino acid gamma-aminobutyrate (GABA)

scientific journal article

PhhR binds to target sequences at different distances with respect to RNA polymerase in order to activate transcription

scientific article

Phosphoglycerate mutase from Schizosaccharomyces pombe: development of an expression system and characterisation of three histidine mutants of the enzyme

article

Physiologically relevant divalent cations modulate citrate recognition by the McpS chemoreceptor

scientific article published on 01 March 2011

Pseudomonas chemotaxis

scientific article published on 04 December 2014

Purification and characterization of Pseudomonas aeruginosa LasR expressed in acyl-homoserine lactone free Escherichia coli cultures.

scientific article

Purification, crystallization and preliminary crystallographic analysis of the ligand-binding regions of the PctA and PctB chemoreceptors from Pseudomonas aeruginosa in complex with amino acids.

scientific article published on 29 November 2013

Qualitative and quantitative assays for flagellum-mediated chemotaxis.

scientific article published in January 2014

RecA protein plays a role in the chemotactic response and chemoreceptor clustering of Salmonella enterica

scientific journal article

Recent advances and future prospects in bacterial and archaeal locomotion and signal transduction

scientific article published on 08 May 2017

Recognition of dominant attractants by key chemoreceptors mediates recruitment of plant growth-promoting rhizobacteria

scientific article published on 08 January 2019

Regulation of glucose metabolism in Pseudomonas: the phosphorylative branch and entner-doudoroff enzymes are regulated by a repressor containing a sugar isomerase domain.

scientific article

Responses of Pseudomonas putida to toxic aromatic carbon sources.

scientific article published in February 2012

Responses of Pseudomonas to small toxic molecules by a mosaic of domains

scientific article published on 09 March 2009

Role of transferrin receptor from a Neisseria meningitidis tbpB isotype II strain in human transferrin binding and virulence

scientific article

Sensing of environmental signals: classification of chemoreceptors according to the size of their ligand binding regions

scientific article published on 25 August 2010

Sensory Repertoire of Bacterial Chemoreceptors

scientific article published on 25 October 2017

Sequence requirements of the ATP-binding site within the C-terminal nucleotide-binding domain of mouse P-glycoprotein: structure-activity relationships for flavonoid binding

scientific article published in August 2001

Solvent tolerance in Gram-negative bacteria

scientific article published on 10 December 2011

Specific gamma-aminobutyrate chemotaxis in pseudomonads with different lifestyle

scientific article published on 26 May 2015

Specificity of the CheR2 methyltransferase in Pseudomonas aeruginosa is directed by a C-terminal pentapeptide in the McpB chemoreceptor

scientific article published on 8 April 2014

Struggling to get a universal meningococcal vaccine and novel uses for bacterial toxins in cancer treatment.

scientific article published on July 2010

Study of the TmoS/TmoT two-component system: towards the functional characterization of the family of TodS/TodT like systems.

scientific article published on 27 December 2011

Tackling the bottleneck in bacterial signal transduction research: high-throughput identification of signal molecules

scientific article published on 21 March 2015

Tactic responses to pollutants and their potential to increase biodegradation efficiency.

scientific article published on 18 December 2012

The Crp regulator of Pseudomonas putida: evidence of an unusually high affinity for its physiological effector, cAMP.

scientific article

The HBM domain: introducing bimodularity to bacterial sensing

scientific article

The IclR family of transcriptional activators and repressors can be defined by a single profile

scientific article published on 5 April 2006

The Molecular Mechanism of Nitrate Chemotaxis via Direct Ligand Binding to the PilJ Domain of McpN

scientific article published on 19 February 2019

The Pseudomonas putida HskA hybrid sensor kinase controls the composition of the electron transport chain

scientific article published on 6 December 2012

The Pseudomonas putida HskA hybrid sensor kinase responds to redox signals and contributes to the adaptation of the electron transport chain composition in response to oxygen availability

scientific article

The TodS-TodT two-component regulatory system recognizes a wide range of effectors and works with DNA-bending proteins

scholarly article

The effect of bacterial chemotaxis on host infection and pathogenicity

scientific article published on 24 October 2017

The enigma of cytosolic two-component systems: a hypothesis

scientific article published on 24 February 2009

The expression of many chemoreceptor genes depends on the cognate chemoeffector as well as on the growth medium and phase.

scientific article published on 8 September 2016

The folding and assembly of the dodecameric type II dehydroquinases.

scientific article published on February 1999

The heat, drugs and knockout systems of microbial biotechnology.

scientific article published on 23 August 2009

The involvement of McpB chemoreceptor from Pseudomonas aeruginosa PAO1 in virulence

scientific article published on 11 September 2019

The multidrug efflux regulator TtgV recognizes a wide range of structurally different effectors in solution and complexed with target DNA: evidence from isothermal titration calorimetry

scientific article

The pGRT1 plasmid of Pseudomonas putida DOT-T1E encodes functions relevant for survival under harsh conditions in the environment

scientific article published on 23 May 2011

The plant compound rosmarinic acid induces a broad quorum sensing response in Pseudomonas aeruginosa PAO1

scientific article published on 10 September 2018

The sensor kinase TodS operates by a multiple step phosphorelay mechanism involving two autokinase domains

scientific article published on 24 February 2009

The shikimate pathway and its branches in apicomplexan parasites

scientific article

The structural basis for signal promiscuity in a bacterial chemoreceptor

scientific article published on 05 October 2020

The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor

scientific article

The three-dimensional structure of shikimate kinase

scientific article published on 01 May 1998

The transcriptional repressor TtgV recognizes a complex operator as a tetramer and induces convex DNA bending

scientific article published on 14 April 2007

The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction

scientific article

The use of Isothermal Titration Calorimetry to unravel chemotactic signaling mechanisms

scientific article published on 24 April 2020

The use of electrospray mass spectrometry to identify an essential arginine residue in type II dehydroquinases

scientific article published on 01 February 1995

The use of mass spectrometry to examine the formation and hydrolysis of the phosphorylated form of phosphoglycerate mutase

scientific article published on 01 February 1995

The use of microcalorimetry to characterize tetanus neurotoxin, pertussis toxin and filamentous haemagglutinin

scientific article published on 01 December 2003

Three dimensional morphology of rabies virus studied by cryo-electron tomography.

scientific article

Transcriptional control by two interacting regulatory proteins: identification of the PtxS binding site at PtxR.

scientific article published on 9 September 2013

Transcriptional control of the main aromatic hydrocarbon efflux pump in Pseudomonas

scientific article published on 20 April 2011

Transferrin-binding protein B of Neisseria meningitidis: sequence-based identification of the transferrin-Binding site confirmed by site-directed mutagenesis

scientific article published on February 2004

Two levels of cooperativeness in the binding of TodT to the tod operon promoter

scientific article

Unbinding forces of single pertussis toxin-antibody complexes measured by atomic force spectroscopy correlate with their dissociation rates determined by surface plasmon resonance

scientific article

List of works by Tino Krell

93 The interaction of shikimate kinase fromErwinia chrystanthemiwith substrates

Affinity-purification of Transferrin-binding protein B under nondenaturing conditions

Amino acid sensor conserved from bacteria to humans

An auxin controls bacterial antibiotics production

Analysis of solvent tolerance in Pseudomonas putida DOT-T1E based on its genome sequence and a collection of mutants

Bacterial chemotaxis towards aromatic hydrocarbons in Pseudomonas

Bacterial sensor kinase TodS interacts with agonistic and antagonistic signals

Bacterial sensor kinases: diversity in the recognition of environmental signals

Bioavailability of pollutants and chemotaxis

Biochemical and X-ray crystallographic studies on shikimate kinase: The important structural role of the P-loop lysine

Biochemical and molecular characterization of the mitochondrial peroxiredoxin PsPrxII F from Pisum sativum

Catabolite repression of the TodS/TodT two-component system and effector-dependent transphosphorylation of TodT as the basis for toluene dioxygenase catabolic pathway control

Characterization of different strains of poliovirus and influenza virus by differential scanning calorimetry

Characterization of molecular interactions using isothermal titration calorimetry.

Chemoperception of Specific Amino Acids Controls Phytopathogenicity in Pseudomonas syringae pv. tomato

Chemoreceptor-based signal sensing

Chemoreceptors with C-terminal pentapeptides for CheR and CheB binding are abundant in bacteria that maintain host interactions

Chemotaxis of the Human Pathogen Pseudomonas aeruginosa to the Neurotransmitter Acetylcholine

Compartmentalized glucose metabolism in Pseudomonas putida is controlled by the PtxS repressor

Complexity in efflux pump control: cross-regulation by the paralogues TtgV and TtgT.

Construction of a prototype two-component system from the phosphorelay system TodS/TodT.

Correlation between signal input and output in PctA and PctB amino acid chemoreceptor of Pseudomonas aeruginosa

Crystal Structures of Multidrug Binding Protein TtgR in Complex with Antibiotics and Plant Antimicrobials

Crystal structure of TtgV in complex with its DNA operator reveals a general model for cooperative DNA binding of tetrameric gene regulators

Crystallization and crystallographic analysis of the ligand-binding domain of the Pseudomonas putida chemoreceptor McpS in complex with malate and succinate

Crystallization and preliminary X-ray crystallographic analysis of shikimate kinase from Erwinia chrysanthemi.

Degeneration of rat cholinergic basal forebrain neurons and reactive changes in nerve growth factor expression after chronic neurotoxic injury—I. Degeneration and plastic response of basal forebrain neurons ⬇️

Degeneration of rat cholinergic basal forebrain neurons and reactive changes in nerve growth factor expression after chronic neurotoxic injury—II. Reactive expression of the nerve growth factor gene in astrocytes ⬇️

Different Modes of Binding of Mono- and Biaromatic Effectors to the Transcriptional Regulator TTGV

Disparate response to microoxia and nitrogen oxides of the Bradyrhizobium japonicum napEDABC, nirK and norCBQD denitrification genes

Diversity at its best: bacterial taxis.

Effect of the β-propiolactone treatment on the adsorption and fusion of influenza A/Brisbane/59/2007 and A/New Caledonia/20/1999 virus H1N1 on a dimyristoylphosphatidylcholine/ganglioside GM3 mixed phospholipids monolayer at the air-water interface

Effector-repressor interactions, binding of a single effector molecule to the operator-bound TtgR homodimer mediates derepression.

Evidence for Pentapeptide-Dependent and Independent CheB Methylesterases

Evidence for chemoreceptors with bimodular ligand-binding regions harboring two signal-binding sites

Evidence for the shikimate pathway in apicomplexan parasites.

Exploring the (almost) unknown: archaeal two-component systems

Fructooligosacharides reduce Pseudomonas aeruginosa PAO1 pathogenicity through distinct mechanisms

Fructose 1-Phosphate Is the Preferred Effector of the Metabolic Regulator Cra of Pseudomonas putida

Fructose 1-phosphate is the one and only physiological effector of the Cra (FruR) regulator of Pseudomonas putida.

Functional Annotation of Bacterial Signal Transduction Systems: Progress and Challenges

Genes encoding Cher-TPR fusion proteins are predominantly found in gene clusters encoding chemosensory pathways with alternative cellular functions.

Genes for carbon metabolism and the ToxA virulence factor in Pseudomonas aeruginosa are regulated through molecular interactions of PtxR and PtxS

Genome Sequence of Serratia marcescens MSU97, a Plant-Associated Bacterium That Makes Multiple Antibiotics

Genome Sequence of Serratia plymuthica A153, a Model Rhizobacterium for the Investigation of the Synthesis and Regulation of Haterumalides, Zeamine, and Andrimid.

GtrS and GltR form a two-component system: the central role of 2-ketogluconate in the expression of exotoxin A and glucose catabolic enzymes in Pseudomonas aeruginosa

HIV-1 gp41 and gp160 are hyperthermostable proteins in a mesophilic environment. Characterization of gp41 mutants.

Hexameric oligomerization of mitochondrial peroxiredoxin PrxIIF and formation of an ultrahigh affinity complex with its electron donor thioredoxin Trx-o

Hierarchical binding of the TodT response regulator to its multiple recognition sites at the tod pathway operon promoter.

High specificity in CheR methyltransferase function: CheR2 of Pseudomonas putida is essential for chemotaxis, whereas CheR1 is involved in biofilm formation.

High-Affinity Chemotaxis to Histamine Mediated by the TlpQ Chemoreceptor of the Human Pathogen Pseudomonas aeruginosa

How Bacterial Chemoreceptors Evolve Novel Ligand Specificities

Identification and purification of a distinct dihydrolipoamide dehydrogenase from pea chloroplasts

Identification of a Chemoreceptor for C2 and C3 Carboxylic Acids

Identification of a chemoreceptor for tricarboxylic acid cycle intermediates: differential chemotactic response towards receptor ligands

Identification of a chemoreceptor that specifically mediates chemotaxis toward metabolizable purine derivatives

Identification of a novel calcium binding motif based on the detection of sequence insertions in the animal peroxidase domain of bacterial proteins

Identification of ligands for bacterial sensor proteins

Identification of new residues involved in intramolecular signal transmission in a prokaryotic transcriptional repressor.

In situ X-ray data collection from highly sensitive crystals of Pseudomonas putida PtxS in complex with DNA.

Insight into the structure and function of the transferrin receptor from Neisseria meningitidis using microcalorimetric techniques

Intramolecular signal transmission in a tetrameric repressor of the IclR family

Is it possible to predict signal molecules that are recognized by bacterial receptors?

Laboratory research aimed at closing the gaps in microbial bioremediation

Localization of the Active Site of Type II Dehydroquinases

McpQ is a specific citrate chemoreceptor that responds preferentially to citrate/metal ion complexes.

Members of the IclR family of bacterial transcriptional regulators function as activators and/or repressors

Microcalorimetry: a response to challenges in modern biotechnology.

Multiple signals modulate the activity of the complex sensor kinase TodS.

Optimization of the palindromic order of the TtgR operator enhances binding cooperativity

Paralogous Regulators ArsR1 and ArsR2 of Pseudomonas putida KT2440 as a Basis for Arsenic Biosensor Development

Paralogous chemoreceptors mediate chemotaxis towards protein amino acids and the non-protein amino acid gamma-aminobutyrate (GABA)

PhhR binds to target sequences at different distances with respect to RNA polymerase in order to activate transcription

Phosphoglycerate mutase from Schizosaccharomyces pombe: development of an expression system and characterisation of three histidine mutants of the enzyme

Physiologically relevant divalent cations modulate citrate recognition by the McpS chemoreceptor

Pseudomonas chemotaxis

Purification and characterization of Pseudomonas aeruginosa LasR expressed in acyl-homoserine lactone free Escherichia coli cultures.

Purification, crystallization and preliminary crystallographic analysis of the ligand-binding regions of the PctA and PctB chemoreceptors from Pseudomonas aeruginosa in complex with amino acids.

Qualitative and quantitative assays for flagellum-mediated chemotaxis.