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List of works by Francisco Conejero-Lara

A binding event converted into a folding event.

scientific article

A single mutation in an SH3 domain increases amyloid aggregation by accelerating nucleation, but not by destabilizing thermodynamically the native state

scientific article

A single mutation induces amyloid aggregation in the alpha-spectrin SH3 domain: analysis of the early stages of fibril formation

scientific article

Characterization of oligomers of heterogeneous size as precursors of amyloid fibril nucleation of an SH3 domain: an experimental kinetics study

scientific article published on 27 November 2012

Cooperative propagation of local stability changes from low-stability and high-stability regions in a SH3 domain

scientific article

Detection and characterization of partially unfolded oligomers of the SH3 domain of alpha-spectrin

scientific article

Differential scanning calorimetric study of carboxypeptidase B, procarboxypeptidase B and its globular activation domain

scientific article published on 01 September 1991

Dynamic micellar oligomers of amyloid beta peptides play a crucial role in their aggregation mechanisms

scientific article published on 01 August 2018

Early mechanisms of amyloid fibril nucleation in model and disease-related proteins

scientific article published on 19 August 2019

Environmental conditions affect the kinetics of nucleation of amyloid fibrils and determine their morphology

scientific article

Evaluation of folding co-operativity of a chimeric protein based on the molecular recognition between polyproline ligands and SH3 domains

scientific article

Expression and characterization of the intact N-terminal domain of streptokinase.

scientific article published on February 1999

Global Protein Stabilization Does Not Suffice to Prevent Amyloid Fibril Formation

scientific article published on 16 July 2018

Liposomal formulation of Gp41 derivate with adjuvant MPLA: vaccine design, immunogenicity in animals and safety in humans.

scientific article published on 13 September 2012

Mapping the structure of amyloid nucleation precursors by protein engineering kinetic analysis

scientific article published on 6 January 2014

Modulation of the stability of amyloidogenic precursors by anion binding strongly influences the rate of amyloid nucleation

scientific article published in October 2013

Molecular and Physicochemical Factors Governing Solubility of the HIV gp41 Ectodomain.

scientific article published on August 2016

Molecular characterisation of a thermoactive beta-1,3-glucanase from Oerskovia xanthineolytica.

scientific article published in September 1996

NMR Solution Structure of the 205−316 C-Terminal Fragment of Thermolysin. An Example of Dimerization Coupled to Partial Unfolding†

scientific article published on 01 September 1997

Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41 with potential as anti-HIV-1 drugs.

scientific article

Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins

scientific article published on 27 June 2019

Structural cooperativity in the SH3 domain studied by site-directed mutagenesis and amide hydrogen exchange.

scientific article

Sublingual Priming with a HIV gp41-Based Subunit Vaccine Elicits Mucosal Antibodies and Persistent B Memory Responses in Non-Human Primates

scientific article published on February 2017

The high-resolution NMR structure of a single-chain chimeric protein mimicking a SH3-peptide complex

scientific article

The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3

scientific article

The influence of N-terminal acetylation on micelle-induced conformational changes and aggregation of α-Synuclein.

scientific article

The influence of effectors and subunit interactions on Escherichia coli carbamoyl-phosphate synthetase studied by differential scanning calorimetry.

scientific article

The thermodynamic stability of amyloid fibrils studied by differential scanning calorimetry

scientific article

The thermodynamics of association and unfolding of the 205-316 C-terminal fragment of thermolysin

scientific article published on 01 September 1995

The thermodynamics of the unfolding of an isolated protein subdomain. The 255-316 C-terminal fragment of thermolysin

scientific article published on 01 May 1994

Thermal stability of the three domains of streptokinase studied by circular dichroism and nuclear magnetic resonance.

scientific article published on December 1996

Thermodynamic analysis of the binding of 2F5 (Fab and immunoglobulin G forms) to its gp41 epitope reveals a strong influence of the immunoglobulin Fc region on affinity

scientific article

Understanding the polymorphic behaviour of a mutant of the α-spectrin SH3 domain by means of two 1.1 Å resolution structures

scientific article

pH dependence of the hydrogen exchange in the SH3 domain of alpha-spectrin.

scientific article