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List of works by Denisa Wagner

A direct role for C1 inhibitor in regulation of leukocyte adhesion

scientific article published in May 2005

A key role for Rac and Pak signaling in neutrophil extracellular traps (NETs) formation defines a new potential therapeutic target

scientific article

A new role in hemostasis for the adhesion receptor P-selectin

scientific article

A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function

scientific journal article

ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice

scientific article published on 01 June 2017

ADAMTS13 Endopeptidase Protects against Vascular Endothelial Growth Factor Inhibitor-Induced Thrombotic Microangiopathy

scientific article

ADAMTS13 exerts a thrombolytic effect in microcirculation

scientific article published on 10 July 2012

ADAMTS13: a new link between thrombosis and inflammation.

scientific article published on 11 August 2008

ARC15105 is a potent antagonist of von Willebrand factor mediated platelet activation and adhesion

scientific article

Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: role of P-selectin

scientific journal article

Antithrombotic activity of TNF-alpha.

scientific article published on November 2003

ApoE deficiency leads to a progressive age-dependent blood-brain barrier leakage

scientific article published on 26 July 2006

Aspirin induces platelet receptor shedding via ADAM17 (TACE)

scientific article (publication date: 2 December 2005)

CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism

scientific article published on 01 March 2002

CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin alphaIIbbeta3 in platelets

scientific article published on 10 June 2008

CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation

scientific journal article

Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis

scientific article

Cellular Mechanisms of NETosis

scientific article published on 14 July 2020

Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies

scientific article

Correction: Lack of Tryptophan Hydroxylase-1 in Mice Results in Gait Abnormalities.

scientific article published on 16 August 2013

Decreased plasma fibronectin leads to delayed thrombus growth in injured arterioles

scientific article published on 09 March 2006

Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice.

scientific article published on 18 November 2011

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

scientific article

Dietary omega-3 alpha-linolenic acid does not prevent venous thrombosis in mice

scientific article published on 18 September 2014

Dynamic Visualization of Thrombopoiesis Within Bone Marrow

scientific article published in Science

Elevated levels of circulating DNA and chromatin are independently associated with severe coronary atherosclerosis and a prothrombotic state.

scientific article published on July 2013

Elevated levels of homocysteine compromise blood-brain barrier integrity in mice

scientific article published on 27 September 2005

Elevated levels of soluble P-selectin in mice alter blood-brain barrier function, exacerbate stroke, and promote atherosclerosis

scientific article published on 06 April 2009

Elevated soluble ICAM-1 levels induce immune deficiency and increase adiposity in mice

scientific article published on 7 April 2005

Endocytosis of soluble immune complexes leads to their clearance by FcγRIIIB but induces neutrophil extracellular traps via FcγRIIA in vivo.

scientific article

Endothelial Von Willebrand factor promotes blood-brain barrier flexibility and provides protection from hypoxia and seizures in mice

scientific article

Extracellular Chromatin Is an Important Mediator of Ischemic Stroke in Mice ⬇️

scientific article published on May 24, 2012

Extracellular DNA NET-Works With Dire Consequences for Health

scientific article published on 01 August 2019

Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice.

scientific article

Extracellular DNA traps promote thrombosis.

scientific article

Extrahepatic high-density lipoprotein receptor SR-BI and apoA-I protect against deep vein thrombosis in mice.

scientific article

Flow cytometric assay for direct quantification of neutrophil extracellular traps in blood samples

scientific article

GPVI down-regulation in murine platelets through metalloproteinase-dependent shedding

scientific article published in May 2004

Glycoprotein Ibalpha and von Willebrand factor in primary platelet adhesion and thrombus formation: lessons from mutant mice

scientific article published on 01 February 2008

Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease

scientific article

Histones induce rapid and profound thrombocytopenia in mice

scientific article

ICAM-1 and beta2 integrin deficiency impairs fat oxidation and insulin metabolism during fasting.

scientific article

In vitro function and phagocytosis of galactosylated platelet concentrates after long-term refrigeration.

scientific article published in March 2007

Increased efficacy of breast cancer chemotherapy in thrombocytopenic mice

scientific article

Inflammation induces hemorrhage in thrombocytopenia

scientific article

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

scientific article published on 26 January 2015

Inhibition of VEGF or TGF-{beta} signaling activates endothelium and increases leukocyte rolling.

scientific article published on 21 May 2009

Innate immune cells induce hemorrhage in tumors during thrombocytopenia

scientific article

Integrin-independent role of CalDAG-GEFI in neutrophil chemotaxis.

scientific article

Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A.

scientific article published on 13 July 2003

Isoflurane inhibits neutrophil recruitment in the cutaneous Arthus reaction model ⬇️

scientific article published on October 25, 2012

Lack of tryptophan hydroxylase-1 in mice results in gait abnormalities

scientific article

Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy

scientific article published on 27 July 2006

Mast Cells Granular Contents Are Crucial for Deep Vein Thrombosis in Mice

scientific article published on 24 July 2017

Mechanisms and implications of platelet discoid shape

scientific article

Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets

scientific article

Mice lacking insulin or insulin-like growth factor 1 receptors in vascular endothelial cells maintain normal blood-brain barrier.

scientific article published in April 2004

Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III.

scientific article

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.

scientific article published on 26 March 2012

Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease

scientific article

NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture

scientific article published on 13 March 2020

NETosis promotes cancer-associated arterial microthrombosis presenting as ischemic stroke with troponin elevation

scientific article published on 12 January 2016

NETosis: a new factor in tumor progression and cancer-associated thrombosis

scientific article

Neutrophil extracellular trap (NET) impact on deep vein thrombosis

scientific article

Neutrophil extracellular traps promote deep vein thrombosis in mice ⬇️

scientific article published on January 1, 2012

Neutrophil extracellular traps: A new link to cancer-associated thrombosis and potential implications for tumor progression

scientific article published on February 2013

Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice.

scientific article published on 6 May 2013

Neutrophils release extracellular DNA traps during storage of red blood cell units

scientific article published on 08 April 2013

New links between inflammation and thrombosis

scientific article

Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor.

scientific article

Oxidative stress activates ADAM17/TACE and induces its target receptor shedding in platelets in a p38-dependent fashion

scientific article published on 29 May 2009

P-selectin and leukocyte microparticles are associated with venous thrombogenesis

scientific article published in November 2003

P-selectin promotes neutrophil extracellular trap formation in mice

scientific article published on 15 May 2015

PAD4 Deficiency Decreases Inflammation and Susceptibility to Pregnancy Loss in a Mouse Model

scientific article published on 9 November 2016

PAD4-deficiency does not affect bacteremia in polymicrobial sepsis and ameliorates endotoxemic shock

scientific article

PSGL-1 regulates platelet P-selectin-mediated endothelial activation and shedding of P-selectin from activated platelets

scientific article published on 01 October 2007

Peptidylarginine deiminase 4: a nuclear button triggering neutrophil extracellular traps in inflammatory diseases and aging

scientific article published on 20 June 2018

Peroxiredoxin1 prevents excessive endothelial activation and early atherosclerosis.

scientific article

Plasma Peptidylarginine Deiminase IV Promotes VWF-Platelet String Formation and Accelerates Thrombosis After Vessel Injury

scientific article published on 28 June 2019

Plasma fibronectin promotes thrombus growth and stability in injured arterioles

scientific article

Platelet P-selectin facilitates atherosclerotic lesion development

scientific article published on 12 December 2002

Platelet adhesion receptors and their ligands in mouse models of thrombosis.

scientific article published on February 2007

Platelet adhesion receptors do not modulate infarct volume after a photochemically induced stroke in mice

scientific article

Platelet glycoprotein Ibα is an important mediator of ischemic stroke in mice

scientific article

Platelet granule secretion continuously prevents intratumor hemorrhage

scientific article

Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice

scientific article

Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage

scientific article

Platelets in Inflammation and Thrombosis ⬇️

scientific article published on September 18, 2003

Platelets: guardians of tumor vasculature

scientific article published on 07 July 2009

Preface

Priming of neutrophils toward NETosis promotes tumor growth.

scientific article published on 18 February 2016

Protective anti-inflammatory effect of ADAMTS13 on myocardial ischemia/reperfusion injury in mice ⬇️

scientific article published on August 22, 2012

Prothrombotic effects of fibronectin isoforms containing the EDA domain

scientific article published on 08 November 2007

Rap1a activation by CalDAG‐GEFI and p38 MAPK is involved in E‐selectin‐dependent slow leukocyte rolling ⬇️

scientific article published on June 7, 2011

Recombinant Human ADAMTS13 Treatment Improves Myocardial Remodeling and Functionality After Pressure Overload Injury in Mice.

scientific article published on 24 January 2018

Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury

scholarly article

Role of syndecan-1 in leukocyte-endothelial interactions in the ocular vasculature

scientific article

Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial Injury: Implications for Superficial Erosion

Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels

scientific article

Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice

scientific article

Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice

scientific article published on 13 December 2017

Systemic antithrombotic effects of ADAMTS13.

scientific article

Targeting platelet function to improve drug delivery ⬇️

scientific article published on January 1, 2012

The A2B adenosine receptor protects against inflammation and excessive vascular adhesion

scientific article

The Clearance Mechanism of Chilled Blood Platelets

scientific article published on 01 January 2003

The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis

scientific article

The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A ⬇️

scientific article published on March 24, 2011

The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation

scientific article

The effect of C1 inhibitor on intestinal ischemia and reperfusion injury

scientific article

The lack of ADAM17 activity during embryonic development causes hemorrhage and impairs vessel formation

scientific article

The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis

scientific article

The vessel wall and its interactions

scientific article published on June 2008

Thrombocytopenia and platelet abnormalities in high-density lipoprotein receptor-deficient mice

scientific article

Thrombosis: tangled up in NETs

scientific article

Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo

scientific article published on 2 September 2004

Unraveling Vascular Inflammation: From Immunology to Imaging.

scientific article published in September 2017

VWF-mediated leukocyte recruitment with chromatin decondensation by PAD4 increases myocardial ischemia/reperfusion injury in mice.

scientific article

p38 mitogen-activated protein kinase activation during platelet storage: consequences for platelet recovery and hemostatic function in vivo

scientific article

von Willebrand factor and factor VIII are independently required to form stable occlusive thrombi in injured veins

scientific article published on 21 November 2006

von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke

scientific article published on 17 August 2009

von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models

scientific article

von Willebrand factor: an emerging target in stroke therapy.

scientific article

von-Willebrand factor influences blood brain barrier permeability and brain inflammation in experimental allergic encephalomyelitis

scientific article published on 7 August 2008

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