List of works - Olivier Delattre

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

scientific article

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

scientific article

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

scientific article

Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

scientific article published on October 2008

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

scientific article

The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts

scientific article

Control-FREEC: a tool for assessing copy number and allelic content using next-generation sequencing data

scientific article

Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

scientific article

Protein interaction mapping: a Drosophila case study

scientific article published on 14 February 2005

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

scientific article

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

scientific article

Mesenchymal stem cell features of Ewing tumors

scientific article

EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts

scientific article

EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.

scientific article published on August 2004

A new model of patient tumor-derived breast cancer xenografts for preclinical assays

scientific article

DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma

scientific article published on May 1994

Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas

article

A new member of the ETS family fused to EWS in Ewing tumors

scientific article

Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers

scientific article

Fusion gene-negative alveolar rhabdomyosarcoma is clinically and molecularly indistinguishable from embryonal rhabdomyosarcoma.

scientific article published on 29 March 2010

Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations

scientific article

The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation

scientific article

Ploidy and large-scale genomic instability consistently identify basal-like breast carcinomas with BRCA1/2 inactivation

scientific article

A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion

scientific article published on 4 March 2012

Ewing Sarcoma: Current Management and Future Approaches Through Collaboration

scientific article published on 24 August 2015

Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

scientific article published on 29 June 2015

The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children

scientific article published on 23 April 2007

Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification

scientific article published on 18 August 2010

Overall genomic pattern is a predictor of outcome in neuroblastoma

scientific article

Germline mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastoma

scientific article

Spectrum of hSNF5/INI1 somatic mutations in human cancer and genotype-phenotype correlations

scientific article published on 01 December 1999

EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.

scientific article

MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma

scientific article (publication date: 2009)

Germline BAP1 mutations predispose to renal cell carcinomas

scientific article published on 16 May 2013

Multiple genetic alterations in distal and proximal colorectal cancer

scientific article published on August 1989

SVDetect: a tool to identify genomic structural variations from paired-end and mate-pair sequencing data

scientific article

Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics

scientific article published in May 2009

PAX3/FOXO1 fusion gene status is the key prognostic molecular marker in rhabdomyosarcoma and significantly improves current risk stratification.

scientific article published on 26 March 2012

Oxidative stress promotes myofibroblast differentiation and tumour spreading

scientific article

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study

scientific article published on 23 February 2017

Control-free calling of copy number alterations in deep-sequencing data using GC-content normalization

scientific article

Does expression of different EWS chimeric transcripts define clinically distinct risk groups of Ewing tumor patients?

scientific article published in April 1996

Analysis of the expression of cell cycle regulators in Ewing cell lines: EWS-FLI-1 modulates p57KIP2and c-Myc expression

scientific article

Cytogenetic prognostication within medulloblastoma subgroups

scientific article published on 03 February 2014

Tumor cell plasticity in Ewing sarcoma, an alternative circulatory system stimulated by hypoxia.

scientific article

Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t(11;22) translocation breakpoints

scientific article published on 01 November 1992

SWI/SNF chromatin remodeling and human malignancies

scientific article

Molecular profiling of patient-derived breast cancer xenografts

scientific article

Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile

scientific article

JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas

scientific article

List of works by Olivier Delattre

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts

Control-FREEC: a tool for assessing copy number and allelic content using next-generation sequencing data

Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

Protein interaction mapping: a Drosophila case study

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

Mesenchymal stem cell features of Ewing tumors

EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts

EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.

A new model of patient tumor-derived breast cancer xenografts for preclinical assays

DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma

Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas

A new member of the ETS family fused to EWS in Ewing tumors

Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers

Fusion gene-negative alveolar rhabdomyosarcoma is clinically and molecularly indistinguishable from embryonal rhabdomyosarcoma.

Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations

The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation

Ploidy and large-scale genomic instability consistently identify basal-like breast carcinomas with BRCA1/2 inactivation

A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion

Ewing Sarcoma: Current Management and Future Approaches Through Collaboration

Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children

Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification

Overall genomic pattern is a predictor of outcome in neuroblastoma

Germline mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastoma

Spectrum of hSNF5/INI1 somatic mutations in human cancer and genotype-phenotype correlations

EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.

MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma

Germline BAP1 mutations predispose to renal cell carcinomas

Multiple genetic alterations in distal and proximal colorectal cancer

SVDetect: a tool to identify genomic structural variations from paired-end and mate-pair sequencing data

Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics

PAX3/FOXO1 fusion gene status is the key prognostic molecular marker in rhabdomyosarcoma and significantly improves current risk stratification.

Oxidative stress promotes myofibroblast differentiation and tumour spreading

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study

Control-free calling of copy number alterations in deep-sequencing data using GC-content normalization

Does expression of different EWS chimeric transcripts define clinically distinct risk groups of Ewing tumor patients?

Analysis of the expression of cell cycle regulators in Ewing cell lines: EWS-FLI-1 modulates p57KIP2and c-Myc expression

Cytogenetic prognostication within medulloblastoma subgroups

Tumor cell plasticity in Ewing sarcoma, an alternative circulatory system stimulated by hypoxia.

Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t(11;22) translocation breakpoints

SWI/SNF chromatin remodeling and human malignancies

Molecular profiling of patient-derived breast cancer xenografts

Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile

JUN oncogene amplification and overexpression block adipocytic differentiation in highly aggressive sarcomas