List of works by Michel Cogné

A class switch control region at the 3′ end of the immunoglobulin heavy chain locus

scientific article published on 01 June 1994

A defect of the INK4-Cdk4 checkpoint and Myc collaborate in blastoid mantle cell lymphoma-like lymphoma formation in mice.

scientific article published on 9 February 2012

A monoclonal V kappa l light chain responsible for incomplete proximal tubulopathy

scientific article published on 01 February 2003

A mouse model recapitulating human monoclonal heavy chain deposition disease evidences the relevance of proteasome inhibitor therapy.

scientific article

A p53 defect sensitizes various stages of B cell development to lymphomagenesis in mice carrying an IgH 3' regulatory region-driven c-myc transgene.

scientific article published on 28 October 2011

A plasma cell differentiation quality control ablates B cell clones with biallelic Ig rearrangements and truncated Ig production

scientific article

AID-driven deletion causes immunoglobulin heavy chain locus suicide recombination in B cells.

scientific article published on 26 April 2012

AID-induced remodeling of immunoglobulin genes and B cell fate

scientific article

Activation-induced deaminase in B lymphocyte maturation and beyond.

scientific article

Age-related alterations of somatic hypermutation and CDR3 lengths in human Vkappa4-expressing B lymphocytes

scientific article published on 01 June 1999

Alleles of the alpha1 immunoglobulin gene 3' enhancer control evolution of IgA nephropathy toward renal failure

scientific article published on 01 September 2000

Alternate splice sites within the human VH gene coding sequences lead to truncated Ig mu-chains.

scientific article published in January 1990

An elevation in the concentration of HLA class I molecules in human blood due to ageing

scientific article published on 01 March 2001

Analysis of IgE down regulation induced by basophil activation. Application to the diagnosis of muscle relaxant allergic hypersensitivity by flow cytometry

scientific article published on 01 April 2006

Analysis of three genetic markers in IgA nephropathy patients from a single region.

scientific article

Animal models of monoclonal immunoglobulin-related renal diseases.

scientific article

Anti-CD20 IgA can protect mice against lymphoma development: evaluation of the direct impact of IgA and cytotoxic effector recruitment on CD20 target cells.

scientific article

B Cell Intrinsic Mechanisms Constraining IgE Memory.

scientific article

B-cell receptor signal strength influences terminal differentiation.

scientific article

Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction

scientific article published in 2022

Brief report: heavy-chain deposition disease

scientific article published on 01 November 1993

CSReport: A New Computational Tool Designed for Automatic Analysis of Class Switch Recombination Junctions Sequenced by High-Throughput Sequencing

scientific article

Characterization of human FCRL4-positive B cells

scientific article

Characterization of the murine gene for subunit VIIaL of cytochrome c oxidase

scientific article published on 01 December 2001

Circulating antibodies to human and bovine cornea in human keratoplasty

scientific article published on 01 April 2000

Circulating free light chain measurement in the diagnosis, prognostic assessment and evaluation of response of AL amyloidosis: comparison of Freelite and N latex FLC assays

scientific article published on 27 March 2017

Class-specific effector functions of therapeutic antibodies.

scientific article

Clinico-biological characteristics of flow cytometry applied to hypersensitivity to NSAIDs

scientific article published on 01 April 2007

Comment on "IgH chain class switch recombination: mechanism and regulation"

scientific article published on 01 March 2015

Complementary DNA sequence of human amyloidogenic immunoglobulin light-chain precursors ⬇️

scientific article published on July 1, 1992

Complete variable region deletion in a mu heavy chain disease protein (ROUL). Correlation with light chain secretion

scientific article published on 01 June 1993

Complexes between nuclear factor-κB p65 and signal transducer and activator of transcription 3 are key actors in inducing activation-induced cytidine deaminase expression and immunoglobulin A production in CD40L plus interleukin-10-treated human blo

article

Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development.

scientific article published on 28 October 2011

Crystal-storing histiocytosis with renal Fanconi syndrome: pathological and molecular characteristics compared with classical myeloma-associated Fanconi syndrome.

scientific article

Cutting edge: Ig heavy chain 3' HS1-4 directs correct spatial position-independent expression of a linked transgene to B lineage cells

scientific article published on 01 November 1999

Deciphering the importance of the palindromic architecture of the immunoglobulin heavy-chain 3' regulatory region.

scientific article published on 17 February 2016

Deregulated platelet-activating factor levels and acetylhydrolase activity in patients with idiopathic IgA nephropathy

scientific article published on 01 September 2000

Detecting Rare AID-Induced Mutations in B-Lineage Oncogenes from High-Throughput Sequencing Data Using the Detection of Minor Variants by Error Correction Method

scientific article published on 13 June 2018

Developmental Switch in the Transcriptional Activity of a Long-Range Regulatory Element.

scientific article

Diffuse small intestinal lymphoid infiltration in nonimmunodeficient adults from Western Europe

scientific article published on 01 August 1988

Effect of the Emu IgH enhancer on expression of a GFP reporter gene in transfected B cells and transgenic mice.

scientific article published on March 2003

Efficient AID targeting of switch regions is not sufficient for optimal class switch recombination.

scientific article

Elucidation of IgH 3' region regulatory role during class switch recombination via germline deletion.

scientific article

Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region.

scientific article

Exon skipping without splice site mutation accounting for abnormal immunoglobulin chains in nonsecretory human myeloma.

scientific article

Eμ and 3'RR IgH enhancers show hierarchic unilateral dependence in mature B-cells

scientific article

Fanconi's syndrome induced by a monoclonal Vkappa3 light chain in Waldenstrom's macroglobulinemia

scientific article published on 01 April 2005

First Membrane Proximal External Region-Specific Anti-HIV1 Broadly Neutralizing Monoclonal IgA1 Presenting Short CDRH3 and Low Somatic Mutations

scientific article published on August 2016

Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire

scientific article published on August 2013

Functional anatomy of the immunoglobulin heavy chain 3΄ super-enhancer needs not only core enhancer elements but also their unique DNA context

scientific article

GM-CSF and IL-12 production by malignant plasma cells promotes cell-mediated immune responses against monoclonal Ig determinants in a light chain myeloma model

scientific article published on 01 August 2002

Gammopathy with IgA mesangial deposition provides a monoclonal model of IgA nephritogenicity and offers new insights into its molecular mechanisms

scientific article published on 31 March 2011

Germ line transcription in mice bearing neor gene downstream of Igamma3 exon in the Ig heavy chain locus

scientific article published on 28 February 2006

Germ-line transcription occurs on both the functional and the non-functional alleles of immunoglobulin constant heavy chain genes

scientific article published on 01 August 2003

HLA-A and HLA-B transcription decrease with ageing in peripheral blood leucocytes

scientific article published on 01 August 2001

Heavy and light chain primary structures control IgG3 nephritogenicity in an experimental model for cryocrystalglobulinemia

scientific article published on 01 June 2000

Human platelets can activate peripheral blood B cells and increase production of immunoglobulins.

scientific article

IGHV gene features and MYD88 L265P mutation separate the three marginal zone lymphoma entities and Waldenström macroglobulinemia/lymphoplasmacytic lymphomas

article

IgA Structure Variations Associate with Immune Stimulations and IgA Mesangial Deposition

scientific article published on 29 January 2016

Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.

scientific article published on 12 February 2004

Immunoglobulin gene alterations in human heavy chain diseases.

scientific article

Immunoglobulin genes undergo legitimate repair in human B cells not only after cis- but also frequent trans-class switch recombination

scientific article published on 22 May 2014

Immunologic basis for the rare occurrence of true nonsecretory plasma cell dyscrasias.

scientific article published on 20 May 2004

Impaired Lysosomal Function Underlies Monoclonal Light Chain-Associated Renal Fanconi Syndrome

scientific article

Indolent lymphoplasmacytic and marginal zone B-cell lymphomas: absence of both IRF4 and Ki67 expression identifies a better prognosis subgroup.

scientific article published in February 2005

Induction of somatic hypermutation by antigen-specific B cell receptors in the human BL2 cell line.

scientific article published on June 2004

Insertion of the IgH locus 3' regulatory palindrome in expression vectors warrants sure and efficient expression in stable B cell transfectants.

scientific article published on November 1998

Insulators to improve expression of a 3(')IgH LCR-driven reporter gene in transgenic mouse models

scientific article published on 01 August 2003

Interallelic Class Switch Recombination Contributes Significantly to Class Switching in Mouse B Cells

scientific article published on 01 May 2005

Interallelic class switch recombination can reverse allelic exclusion and allowtrans-complementation of an IgH locus switching defect

scientific article published on 01 August 2006

Light chain myeloma plasma cells induce a strong cell-mediated immune response mainly directed against the monoclonal light chain determinants in a murine experimental model

scientific article published on 29 March 2002

Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination

scientific article published on 01 August 2001

Locus suicide recombination actively occurs on the functionally rearranged IgH allele in B-cells from inflamed human lymphoid tissues

scientific article published on 14 June 2019

Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.

scientific article

Major histocompatibility complex restriction of tetanus toxoid-specific human T lymphocyte clones

scientific article published on 01 December 1984

Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin.

scientific article published on May 2012

Membrane isoforms of human immunoglobulins of the A1 and A2 isotypes: structural and functional study.

scientific article published on March 1997

Modification of HLA expression on peripheral lymphocytes and monocytes during aging

scientific article published on 01 November 1998

Molecular cloning and nucleotide sequence of a cDNA encoding hydroxyindole O-methyltransferase from chicken pineal gland ⬇️

scientific article published on March 1, 1992

Molecular study of an IgG1kappa cryoglobulin yielding organized microtubular deposits and glomerulonephritis in the course of chronic lymphocytic leukaemia

scientific article published on 01 July 2002

Monoclonal Ig L chain and L chain V domain fragment crystallization in myeloma-associated Fanconi's syndrome.

scientific article published in April 1993

Monoclonal immunoglobulin deposition disease (Randall type). Relationship with structural abnormalities of immunoglobulin chains

scientific article published on 01 October 1994

Mutational analysis in murine models for myeloma-associated Fanconi's syndrome or cast myeloma nephropathy

scientific article published on 01 November 1999

Nonsecretory alpha-chain disease with immunoproliferative small-intestinal disease

scientific article published on 01 June 1989

Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry

scientific article published in April 2017

Nuclear factors, hs1,2 enhancer and IgA nephropathy

scientific article published on 01 February 2003

Optimisation of HLA-B27 Testing by Association of Flow Cytometry and DNA Typing

scientific article published on 01 January 1999

Palindromic structure of the IgH 3'locus control region.

scientific article published in September 1996

Paraoxonase 1 192/55 gene polymorphisms in Alzheimer's disease.

scientific article published in November 2002

Platelet activation after aortic prosthetic valve surgery

scientific article published on 24 November 2005

Polyclonal IgG4 hypergammaglobulinemia associated with plasmacytic lymphadenopathy, anemia and nephropathy.

scientific article published on 27 July 2006

Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia

scientific article published on 23 October 2011

Polymorphism of the human alpha1 immunoglobulin gene 3' enhancer hs1,2 and its relation to gene expression

scientific article published on 01 May 2001

Primary structure of a monoclonal κ chain in myeloma with light chain deposition disease ⬇️

scientific article published on January 1, 1992

Primary structure of a variable region of the V kappa I subgroup (ISE) in light chain deposition disease.

scientific article published in March 1993

Production of human or humanized antibodies in mice

scientific article published on 01 January 2012

Recombinaisons suicides du locus IgH

scientific article published on 30 May 2012

Regulatory elements of the mb-1 gene encoding the Ig-alpha component of the human B-cell antigen receptor

scientific article published on 01 December 1996

Reversal of the relative expression of cardiac and skeletal alpha1 subunit isoforms of L-type calcium channel during in vitro myogenesis

scientific article published on 01 January 1997

Role of light chain variable region in myeloma with light chain deposition disease: evidence from an experimental model

scientific article published on 01 November 1995

Role of the monoclonal kappa chain V domain and reversibility of renal damage in a transgenic model of acquired Fanconi syndrome

scientific article published on 16 March 2006

Self-Restrained B Cells Arise following Membrane IgE Expression.

scientific article published on 12 February 2015

Self-control for IgE production.

scientific article published in August 2015

Sequences of V kappa L subgroup light chains in Fanconi's syndrome. Light chain V region gene usage restriction and peculiarities in myeloma-associated Fanconi's syndrome.

scientific article published on September 1995

Sequential activation and distinct functions for distal and proximal modules within the IgH 3' regulatory region

scientific article published on February 2016

Similarity of fine specificity of IgA anti-gliadin antibodies between patients with celiac disease and humanized α1KI mice.

scientific article

Splenic marginal zone lymphomas and lymphoplasmacytic lymphomas originate from B-cell compartments with two different antigen-exposure histories

scientific article published on 28 February 2008

Strategies to model AL amyloidosis in mice.

scientific article

Structurally abnormal immunoglobulins in human immunoproliferative disorders.

scientific article

Structure and expression of the mb-1 transcript in human lymphoid cells

scientific article published on October 1, 1992

Structure of abnormal heavy chains in human heavy-chain-deposition disease.

scientific article

The Eμ enhancer region influences H chain expression and B cell fate without impacting IgVH repertoire and immune response in vivo

scientific article published on 25 June 2014

The Ig(kappa) enhancer influences the ratio of Ig(kappa) versus Ig(lambda) B lymphocytes

scientific article published on 01 September 1996

The IgH 3' regulatory region and its implication in lymphomagenesis.

scientific article published on December 2010

The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells

scientific article published on July 2013

The IgH 3' regulatory region governs μ chain transcription in mature B lymphocytes and the B cell fate.

scientific article published on March 2015

The IgH 3' regulatory region influences lymphomagenesis in Igλ-Myc mice

scientific article published on 29 April 2015

The IgH locus 3' cis-regulatory super-enhancer co-opts AID for allelic transvection

scientific article published on 10 January 2017

The beta-globin HS4 insulator confers copy-number dependent expression of IgH regulatory elements in stable B cell transfectants

scientific article published on 01 October 2003

The chicken beta-globin HS4 insulator is not a silver bullet to obtain copy-number dependent expression of transgenes in stable B cell transfectants

scientific article published on 01 January 2005

The effect of intron sequences on expression levels of Ig cDNAs.

scientific article published on December 1994

The immunoglobulin heavy-chain locus hs3b and hs4 3' enhancers are dispensable for VDJ assembly and somatic hypermutation

scientific article published on 24 April 2003

The polymorphism of the locus control region lying downstream the human IgH locus is restricted to hs1,2 but not to hs3 and hs4 enhancers.

scientific article

Total and IgE antibody levels following booster immunization with aluminum absorbed and nonabsorbed tetanus toxoid in humans

scientific article published on 01 February 1985

Toward understanding renal Fanconi syndrome: step by step advances through experimental models.

scientific article published on 20 January 2011

Transcription-dependent somatic hypermutation occurs at similar levels on functional and nonfunctional rearranged IgH alleles.

scientific article

Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.

scientific article published on 26 March 2012

Unravelling the immunopathological mechanisms of heavy chain deposition disease with implications for clinical management.

scientific article published on 20 October 2016

Use of both CD63 up regulation and IgE down regulation for the flow cytometric analysis of allergen induced basophil activation. Definition of an activation index.

scientific article published in July 2007

[Humoral immunity. B lymphocytes; immunoglobulins (structure, diversity, function); clinical practice investigations; concept of humoral immunity deficiency]

scientific article published on 01 January 2001

[Monoclonal gammopathies]

scientific article published on 01 May 2004

[Physiopathology of bullous pemphigoid]

scientific article published on 26 May 2009

[Transgenesis and humanization of murine antibodies]

scientific article published on 01 December 2009

[When immunoglobulin genes assemble with bricks from other chromosomes]

scientific article published on 12 September 2016

Paulina is supported by:

About Paulina

Help