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List of works by Helgi B. Schiöth

A Genetic Risk Score Is Associated with Weight Loss Following Roux-en Y Gastric Bypass Surgery

scientific article published on 30 January 2016

A MIR4646 associated methylation locus is hypomethylated in adolescent depression

scientific article published on 17 May 2017

A genetic risk score is differentially associated with migraine with and without aura

scientific article

A genetic risk score is significantly associated with statin therapy response in the elderly population

scientific article published on 13 October 2016

A genetic variant in proximity to the gene LYPLAL1 is associated with lower hunger feelings and increased weight loss following Roux-en-Y gastric bypass surgery

scientific article published on 16 May 2016

A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers

scientific article published on July 2017

A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score

scientific article published on 17 January 2017

A new, simple and robust radioligand binding method used to determine kinetic off-rate constants for unlabeled ligands. Application at α2A- and α2C-adrenoceptors

scientific article published on 15 June 2016

A resting-state fMRI study of obese females between pre- and postprandial states before and after bariatric surgery

scientific article

A significant participation of orexin-A, a potent orexigenic peptide, in the preovulatory luteinizing hormone and prolactin surges in the rat.

scientific article published in April 2001

A single night of partial sleep loss impairs fasting insulin sensitivity but does not affect cephalic phase insulin release in young men.

scientific article published on 11 September 2015

A single night of sleep loss impairs objective but not subjective working memory performance in a sex-dependent manner

scientific article published on 31 January 2018

A systematic review of resting-state functional-MRI studies in anorexia nervosa: Evidence for functional connectivity impairment in cognitive control and visuospatial and body-signal integration

scientific article

A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease

scientific article

ACTH- and alpha-MSH-induced grooming, stretching, yawning and penile erection in male rats: site of action in the brain and role of melanocortin receptors

scientific article published on 01 March 2000

Activation of central melanocortin-4 receptor suppresses lipopolysaccharide-induced fever in rats ⬇️

scientific article published on June 1, 2003

Activation of melanocortin 4 receptors reduces the inflammatory response and prevents apoptosis induced by lipopolysaccharide and interferon-gamma in astrocytes

scientific article published on 26 June 2007

Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men.

scientific article published on 13 July 2015

Acute ghrelin administration reverses depressive-like behavior induced by bilateral olfactory bulbectomy in mice

scientific article published on 13 April 2012

Acute sleep deprivation enhances the brain's response to hedonic food stimuli: an fMRI study

scientific article

Acute sleep deprivation in healthy young men: impact on population diversity and function of circulating neutrophils

scientific article

Acute sleep deprivation increases food purchasing in men.

scientific article published on 5 September 2013

Acute sleep deprivation increases portion size and affects food choice in young men.

scientific article

Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men.

scientific article

Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans

Addition of a signal peptide sequence to the alpha1D-adrenoceptor gene increases the density of receptors, as determined by [3H]-prazosin binding in the membranes

scientific article published in March 2005

Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract

scientific article

Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet

scientific article

Adolescents newly diagnosed with eating disorders have structural differences in brain regions linked with eating disorder symptoms

scientific article published on 15 November 2016

Advances in kinase targeting: current clinical use and clinical trials

scientific article

Agouti-related peptide prevents steroid-induced luteinizing hormone and prolactin surges in female rats

scientific article

Alpha-melanocyte-stimulating hormone through melanocortin-4 receptor inhibits nitric oxide synthase and cyclooxygenase expression in the hypothalamus of male rats

scientific article

Altered cerebellar-insular-parietal-cingular subnetwork in adolescents in the earliest stages of anorexia nervosa: a network-based statistic analysis.

scientific article published on 6 July 2018

Alternative translation initiation codon for the human melanocortin MC3 receptor does not affect the ligand binding

scientific article published on 01 October 1996

An obesity-associated risk allele within the FTO gene affects human brain activity for areas important for emotion, impulse control and reward in response to food images

scientific article

Analysis of the network of feeding neuroregulators using the Allen Brain Atlas

scientific article

Anorexia nervosa is linked to reduced brain structure in reward and somatosensory regions: a meta-analysis of VBM studies

scientific article

Anorexigenic cocaine- and amphetamine-regulated transcript peptide intensifies fear reactions in rats.

scientific article

Anxiety Disorders are Associated with Low Socioeconomic Status in Women but Not in Men.

scientific article published on 15 February 2017

Are You Sure? Confidence about the Satiating Capacity of a Food Affects Subsequent Food Intake

scientific article published on 24 June 2015

Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI.

scientific article

Association between physical activity and brain health in older adults

scientific article

Association between shift work history and performance on the trail making test in middle-aged and elderly humans: the EpiHealth study

scientific article published on 14 May 2016

Association of TMEM18 variants with BMI and waist circumference in children and correlation of mRNA expression in the PFC with body weight in rats

scientific article

Association of feather colour with constitutively active melanocortin 1 receptors in chicken

scientific article published on April 2003

Association of the LINGO2-related SNP rs10968576 with body mass in a cohort of elderly Swedes

scientific article published on 25 February 2015

Associations Between the Prevalence of Metabolic Syndrome and Sleep Parameters Vary by Age.

scientific article

Associations of self-reported sleep disturbance and duration with academic failure in community-dwelling Swedish adolescents: sleep and academic performance at school

scientific article

Atypical anorexia nervosa is not related to brain structural changes in newly diagnosed adolescent patients

scientific article published on 7 December 2017

Autoradiographic discrimination of melanocortin receptors indicates that the MC3 subtype dominates in the medial rat brain

scientific article

Avian melanocortin system: alpha-MSH may act as an autocrine/paracrine hormone: a minireview

scientific article

B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain

scientific article

BDNF DNA methylation changes as a biomarker of psychiatric disorders: literature review and open access database analysis

scientific article

BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population

scientific article published on 23 January 2014

Binding of cyclic and linear MSH core peptides to the melanocortin receptor subtypes

scientific article published on January 1997

Bis-(2-ethylhexyl) Phthalate Increases Insulin Expression and Lipid Levels in Drosophila melanogaster

scientific article published on 24 March 2016

Brain insulin signaling and Alzheimer's disease: current evidence and future directions

scientific article

CDKAL1-related single nucleotide polymorphisms are associated with insulin resistance in a cross-sectional cohort of Greek children ⬇️

scientific article

Candidate mechanisms underlying the association between sleep-wake disruptions and Alzheimer's disease

scientific article

Central ghrelin increases anxiety in the Open Field test and impairs retention memory in a passive avoidance task in neonatal chicks

scientific article published on 31 January 2009

Central nociceptin/orphanin FQ system elevates food consumption by both increasing energy intake and reducing aversive responsiveness

scientific article published on 28 April 2010

Characterisation of D117A and H260A mutations in the melanocortin 1 receptor

scientific article published on February 1997

Characterisation of melanocortin receptor subtypes by radioligand binding analysis

scientific article published on 01 February 1995

Characterisation of the melanocortin 4 receptor by radioligand binding

scientific article published on 01 September 1996

Characterization of the binding of MSH-B, HP-228, GHRP-6 and 153N-6 to the human melanocortin receptor subtypes ⬇️

scientific article published on December 1, 1997

Characterization of the transporterB0AT3 (Slc6a17) in the rodent central nervous system ⬇️

scientific article published on May 14, 2013

Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake

scientific article

Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes

scientific article published on 9 May 2016

Chimeric Melanocortin MC1 and MC3 Receptors: Identification of Domains Participating in Binding of Melanocyte-Stimulating Hormone Peptides ⬇️

scientific article published on July 1, 1998

Chronic melanocortin 4 receptor blockage causes obesity without influencing sexual behavior in male rats

scientific article published on 01 August 2000

Chronic sugar intake dampens feeding-related activity of neurons synthesizing a satiety mediator, oxytocin

scientific article

Classification, Nomenclature, and Structural Aspects of Adhesion GPCRs

scientific article published on January 2016

Cloning of two melanocortin (MC) receptors in spiny dogfish: MC3 receptor in cartilaginous fish shows high affinity to ACTH-derived peptides while it has lower preference to gamma-MSH.

scientific article

Cloning, tissue distribution, pharmacology and three-dimensional modelling of melanocortin receptors 4 and 5 in rainbow trout suggest close evolutionary relationship of these subtypes

scientific article

Collagen metabolism is a novel target of the neuropeptide alpha-melanocyte-stimulating hormone

scientific article published on 28 November 2003

Comparison of the current RefSeq, Ensembl and EST databases for counting genes and gene discovery

scientific article published in January 2005

Complexity of neural mechanisms underlying overconsumption of sugar in scheduled feeding: involvement of opioids, orexin, oxytocin and NPY

scientific journal article

Comprehensive analysis of localization of 78 solute carrier genes throughout the subsections of the rat gastrointestinal tract

scientific article

Comprehensive comparisons of the current human, mouse, and rat RefSeq, Ensembl, EST, and FANTOM3 datasets: identification of new human genes with specific tissue expression profile

scientific article published on 4 August 2006

Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse

scientific article

Correction: Limbic-thalamo-cortical projections and reward-related circuitry integrity affects eating behavior: A longitudinal DTI study in adolescents with restrictive eating disorders

scientific article published on 20 April 2017

Correction: Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus

scientific article published on 5 June 2017

Corticotropin-releasing factor (CRF) induced anorexia is not influenced by a melanocortin 4 receptor blockage

scientific article

Critical evaluation of the FANTOM3 non-coding RNA transcripts

article

Decreased memory for novel object recognition in chronically food-restricted mice is reversed by acute ghrelin administration

scientific article published on 20 March 2008

Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish

scientific article

Deletions of the N‐terminal regions of the human melanocortin receptors ⬇️

scientific article published on June 30, 1997

Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly

scientific article

Determinants of shortened, disrupted, and mistimed sleep and associated metabolic health consequences in healthy humans

scientific article

Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children

scientific article

Dibutyl Phthalate Exposure Disrupts Evolutionarily Conserved Insulin and Glucagon-Like Signaling in Drosophila Males

scientific article

Dietary fat quality impacts genome-wide DNA methylation patterns in a cross-sectional study of Greek preadolescents

scientific article

Dietary intake of eicosapentaenoic and docosahexaenoic acids is linked to gray matter volume and cognitive function in elderly

scientific article published on 13 July 2012

Differential effects of fluoxetine and venlafaxine on memory recognition: Possible mechanisms of action ⬇️

scientific article published on March 15, 2012

Differential effects of melanocortin peptides on ingestive behaviour in rats: evidence against the involvement of MC(3) receptor in the regulation of food intake

scientific article

Differential expressions of melanocortin receptor subtypes in melanophores and xanthophores of barfin flounder

scientific article published on 24 April 2010

Differential influence of a selective melanocortin MC4 receptor antagonist (HS014) on melanocortin-induced behavioral effects in rats

scientific article published in December 1998

Differential neural responses to food images in women with bulimia versus anorexia nervosa

scientific article

Differential regulation of nuclear receptors, neuropeptides and peptide hormones in the hypothalamus and pituitary of food restricted rats

scientific article

Differential role of the hippocampus, amygdala, and dorsal raphe nucleus in regulating feeding, memory, and anxiety-like behavioral responses to ghrelin

scientific article

Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024): evaluation in vitro and in vivo

scientific article published in December 1998

Discovery of novel melanocortin4 receptor selective MSH analogues ⬇️

scientific article (publication date: May 1998)

Dissecting signaling and functions of adhesion G protein-coupled receptors.

scientific article published on 7 December 2012

Dissection of the Anti-Inflammatory Effect of the Core and C-Terminal (KPV) α-Melanocyte-Stimulating Hormone Peptides ⬇️

scientific article published on May 15, 2003

Diurnal rhythm of circulating nicotinamide phosphoribosyltransferase (Nampt/visfatin/PBEF): impact of sleep loss and relation to glucose metabolism

scientific article published on 16 November 2011

Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced obesity phenotype in rats ⬇️

scientific article published on September 26, 2010

Downregulation of melanocortin receptors in brain areas involved in food intake and reward mechanisms in obese (OLETF) rats

scientific article published in January 2000

Early vertebrate origin of melanocortin 2 receptor accessory proteins (MRAPs) ⬇️

scientific article published on January 29, 2013

Effect of repeated administration of prolactin releasing peptide on feeding behavior in rats

scientific article published in November 2002

Effects of melanocortin receptor ligands on ethanol intake and opioid peptide levels in alcohol-preferring AA rats

scientific article published in October 2002

Efficacy of antibody-based therapies to treat Alzheimer's disease: just a matter of timing?

scientific article published on 14 May 2014

Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents

scientific article published on 18 December 2017

Epigenomics of Total Acute Sleep Deprivation in Relation to Genome-Wide DNA Methylation Profiles and RNA Expression

scientific article published on June 2016

Evaluation of EST-data using the genome assembly

scientific article

Evaluation of behavioural effects of neural melanocortin receptor antagonists injected ICV and in VTA in rats

scientific article

Evaluation of the role for prolactin-releasing peptide in prolactin secretion induced by ether stress and suckling in the rat: comparison with vasoactive intestinal peptide

scientific article published on 01 May 2000

Evidence for expression of melanocortin-1 receptor in human sebocytes in vitro and in situ

scientific article published on March 2002

Evidence for involvement of the melanocortin MC4 receptor in the effects of leptin on food intake and body weight

scientific article published on October 1998

Evidence indicating that the TM4, EL2, and TM5 of the melanocortin 3 receptor Do not participate in ligand binding

scientific article published on December 1996

Evidence indicating that the extracellular loops of the mouse MC5 receptor do not participate in ligand binding ⬇️

scientific article published on April 30, 1998

Evidence that alpha-MSH induced grooming is not primarily mediated by any of the cloned melanocortin receptors

scientific article published on 01 April 2000

Evidence that melanocortin 4 receptor mediates hemorrhagic shock reversal caused by melanocortin peptides

scientific article published on 01 December 1999

Evidence that orexigenic effects of melanocortin 4 receptor antagonist HS014 are mediated by neuropeptide Y.

scientific article published on July 1998

Evidence that physiological levels of circulating leptin exert a stimulatory effect on luteinizing hormone and prolactin surges in rats

scientific article published on 01 September 1999

Evidence that the effect of melanocortins on female sexual behavior in preoptic area is mediated by the MC3 receptor; Participation of nitric oxide

scientific article

Evolutionary conservation of the structural, pharmacological, and genomic characteristics of the melanocortin receptor subtypes

scientific article published in October 2005

Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families

scientific article published on 20 May 2015

Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects

scientific article published on April 2013

Expansion of the superfamily of G-protein-coupled receptors in chordates

scientific article

Experimenter gender and replicability in science

scientific article published on 10 January 2018

Exposure to a high-fat high-sugar diet causes strong up-regulation of proopiomelanocortin and differentially affects dopamine D1 and D2 receptor gene expression in the brainstem of rats

scientific article published on 19 November 2013

Exposure to bisphenol A affects lipid metabolism in Drosophila melanogaster

scientific article published on 11 December 2013

Expression levels of genes encoding melanin concentrating hormone (MCH) and MCH receptor change in taste aversion, but MCH injections do not alleviate aversive responses ⬇️

scientific article published on September 7, 2011

Expression of functional melanocortin 1 receptors in insect cells

scientific article published on April 1996

Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat

scientific article published in 2008

Extensive neuroadaptive changes in cortical gene-transcript expressions of the glutamate system in response to repeated intermittent MDMA administration in adolescent rats ⬇️

scientific article

Fat mass and obesity-associated gene (FTO) is linked to higher plasma levels of the hunger hormone ghrelin and lower serum levels of the satiety hormone leptin in older adults

scientific article published on 4 June 2014

Feed-forward mechanisms: Addiction-like behavioral and molecular adaptations in overeating ⬇️

scientific article published on January 28, 2012

Feeding responses to a melanocortin agonist and antagonist in obesity induced by a palatable high-fat diet

scientific article published in March 2005

Food conversion is transiently affected during 4-week chronic administration of melanocortin agonist and antagonist in rats

scientific article

Food deprivation increases the expression of melanocortin-4 receptor in the liver of barfin flounder, Verasper moseri

scientific article published on 13 May 2007

Formation of new genes explains lower intron density in mammalian Rhodopsin G protein-coupled receptors.

scientific article published on 17 November 2006

Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes

scientific article (publication date: 29 June 2007)

Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway

scientific article

Functional role, structure, and evolution of the melanocortin-4 receptor

scientific article

Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae ⬇️

scientific article

Further evidence for a significant participation of the melanocortin 4 receptor in the preovulatory prolactin surge in the rat.

scientific article published in March 2001

Further evidence for ancient role of ACTH peptides at melanocortin (MC) receptors; pharmacology of dogfish and lamprey peptides at dogfish MC receptors

scientific article

Further pharmacological characterization of the selective melanocortin 4 receptor antagonist HS014: comparison with SHU9119

scientific article

G Protein–Coupled Receptor Deorphanizations ⬇️

scientific article published on September 28, 2012

G protein-coupled receptors in regulation of body weight

scientific article published in June 2006

Gabaergic control of anxiety-like behavior, but not food intake, induced by ghrelin in the intermediate medial mesopallium of the neonatal chick

scientific article published on 9 December 2014

General Principles of Neuronal Co-transmission: Insights From Multiple Model Systems

article

Genetic algorithm for large-scale maximum parsimony phylogenetic analysis of proteins

scientific article

Genetic and expression studies of SMN2 gene in Russian patients with spinal muscular atrophy type II and III ⬇️

scientific article published on July 15, 2011

Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children ⬇️

scientific article published on February 8, 2011

Genome wide analysis reveals association of a FTO gene variant with epigenetic changes

scientific article

Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity

scientific article

Genome-wide analysis shows association of epigenetic changes in regulators of Rab and Rho GTPases with spinal muscular atrophy severity

scientific article published on 09 January 2013

Ghrelin and memory: differential effects on acquisition and retrieval

scientific article published on 7 March 2010

Ghrelin effects expression of several genes associated with depression-like behavior

scientific article

Ghrelin in the CNS: from hunger to a rewarding and memorable meal?

scientific article published on 13 February 2008

Ghrelin increases anxiety-like behavior and memory retention in rats

scientific article

Ghrelin increases memory consolidation through hippocampal mechanisms dependent on glutamate release and NR2B-subunits of the NMDA receptor

scientific article published on 4 December 2014

Ghrelin induced memory facilitation implicates nitric oxide synthase activation and decrease in the threshold to promote LTP in hippocampal dentate gyrus

scientific article

Ghrelin inhibited serotonin release from hippocampal slices ⬇️

scientific article published on July 27, 2011

Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression

scientific article

Growth hormone-releasing hormone improves cognitive function in older adults: sleep on it.

scientific article published in April 2013

High Affinity Agonistic Metal Ion Binding Sites within the Melanocortin 4 Receptor Illustrate Conformational Change of Transmembrane Region 3 ⬇️

scientific article published on September 30, 2003

High diversity in functional properties of melanocortin 1 receptor (MC1R) in divergent primate species is more strongly associated with phylogeny than coat color

scientific article

High leptin levels are associated with migraine with aura

scientific article

Higher resting-state activity in reward-related brain circuits in obese versus normal-weight females independent of food intake

scientific article published on 28 June 2016

Highly diversified expansions shaped the evolution of membrane bound proteins in metazoans

scientific article

Hippocampal effects of neuronostatin on memory, anxiety-like behavior and food intake in rats ⬇️

scientific article published on September 22, 2011

Hyperphagia modifies FA profiles of plasma phospholipids, plasma FFA, and adipose tissue TAG.

scientific article published in November 2003

Hypothalamic FTO is associated with the regulation of energy intake not feeding reward

scientific article

IL-1β reduces GluA1 phosphorylation and its surface expression during memory reconsolidation and α-melanocyte-stimulating hormone can modulate these effects

scientific article published on 14 October 2017

Identification and analysis of functionally important amino acids in human purinergic 12 receptor using a Saccharomyces cerevisiae expression system

article

Identification of distant Agouti-like sequences and re-evaluation of the evolutionary history of the Agouti-related peptide (AgRP).

scientific article

Identification of domains responsible for specific membrane transport and ligand specificity of the ACTH receptor (MC2R).

scientific article

Identification of neurotransmitter receptor genes involved in alcohol self-administration in the rat prefrontal cortex, hippocampus and amygdala

scientific journal article

Identification of novel splice variants of Adhesion G protein-coupled receptors

scientific article published on 30 August 2006

Identification of somatostatin receptor type 5 gene polymorphisms associated with acromegaly ⬇️

scientific article published on August 2, 2011

Impact of nandrolone decanoate on gene expression in endocrine systems related to the adverse effects of anabolic androgenic steroids

scientific article

Impaired insulin sensitivity as indexed by the HOMA score is associated with deficits in verbal fluency and temporal lobe gray matter volume in the elderly

scientific article published in February 2012

Implication of coronin 7 in body weight regulation in humans, mice and flies

scientific article

Increased impulsivity in response to food cues after sleep loss in healthy young men

scientific article

Increased mRNA levels of tyrosine hydroxylase and dopamine transporter in the VTA of male rats after chronic food restriction

scientific article published in January 2006

Increased prefrontal and parahippocampal activation with reduced dorsolateral prefrontal and insular cortex activation to food images in obesity: a meta-analysis of fMRI studies

scientific article

Independent HHsearch, Needleman--Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families

scientific article

Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study

scientific article published on 28 February 2017

Insights into the origin of nematode chemosensory GPCRs: putative orthologs of the Srw family are found across several phyla of protostomes

scientific article

Insulin receptor-like ectodomain genes and splice variants are found in both arthropods and human brain cDNA

scientific article

Insulin to treat Alzheimer's disease: just follow your nose?

scientific article published in January 2012

Interleukin-1β-induced memory reconsolidation impairment is mediated by a reduction in glutamate release and zif268 expression and α-melanocyte-stimulating hormone prevented these effects

scientific article

Intranasal insulin as a therapeutic option in the treatment of cognitive impairments

scientific article published on 16 September 2010

Intranasal insulin enhances postprandial thermogenesis and lowers postprandial serum insulin levels in healthy men

scientific article

Intranasal insulin in Alzheimer's disease: Food for thought

scientific article published on 24 November 2017

Intranasal treatment of central nervous system dysfunction in humans

scientific article

Inverse association of high-fat diet preference and anxiety-like behavior: a putative role for urocortin 2.

scientific article

Involvement of prolactin-releasing peptide in the preovulatory luteinizing hormone and prolactin surges in the rat

scientific article published on 01 December 2000

Involvement of the neutral amino acid transporter SLC6A15 and leucine in obesity-related phenotypes

scientific article (publication date: 2013)

Kiwi genome provides insights into evolution of a nocturnal lifestyle

scientific article

Late-life alcohol consumption and cognitive function in elderly men.

scientific article published on 07 May 2013

Late-life obesity is associated with smaller global and regional gray matter volumes: a voxel-based morphometric study

scientific article published on 31 January 2012

Learning and sleep-dependent consolidation of spatial and procedural memories are unaltered in young men under a fixed short sleep schedule

scientific article

Limbic-thalamo-cortical projections and reward-related circuitry integrity affects eating behavior: A longitudinal DTI study in adolescents with restrictive eating disorders

scientific article

Long evolutionary conservation and considerable tissue specificity of several atypical solute carrier transporters

scientific article published on October 29, 2010

Long term orexigenic effect of a novel melanocortin 4 receptor selective antagonist

scientific article published on January 1999

Long-term oral melatonin administration reduces ethanol-induced increases in duodenal mucosal permeability and motility in rats.

scientific article

Longitudinal genome-wide methylation study of Roux-en-Y gastric bypass patients reveals novel CpG sites associated with essential hypertension

scientific article

Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction

scientific article

MC(3) receptors are involved in the protective effect of melanocortins in myocardial ischemia/reperfusion-induced arrhythmias

scientific article published on 24 May 2002

MDMA (Ecstasy) decreases the number of neurons and stem cells in embryonic cortical cultures.

scientific article published on 19 June 2009

Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes

scientific article published on 4 February 2008

Major pharmacological distinction of the ACTH receptor from other melanocortin receptors

scientific article

Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers

scientific article

Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin

scientific article published in 2009

Mediterranean diet habits in older individuals: associations with cognitive functioning and brain volumes

scientific article published on 11 October 2013

Melanin-concentrating hormone (MCH) reverts the behavioral effects induced by inescapable stress

scientific article

Melanocortin 4 receptor activation inhibits presynaptic N-type calcium channels in amygdaloid complex neurons

scientific article published on 18 June 2014

Melanocortin 4 receptor constitutive activity inhibits L-type voltage-gated calcium channels in neurons

scientific article published on 13 January 2017

Melanocortin peptides affect the motivation to feed in rainbow trout (Oncorhynchus mykiss).

scientific article published on 8 November 2008

Melanocortins and feeding behavior.

scientific article

Methylation of HPA axis related genes in men with hypersexual disorder

scientific article published on 10 March 2017

Modeling of the three-dimensional structure of the human melanocortin 1 receptor, using an automated method and docking of a rigid cyclic melanocyte-stimulating hormone core peptide ⬇️

scientific article published on October 1, 1997

Molecular mechanisms involved in interleukin 1-beta (IL-1β)-induced memory impairment. Modulation by alpha-melanocyte-stimulating hormone (α-MSH) ⬇️

scientific article published on August 20, 2013

Molecular mechanisms underlying anorexia nervosa: focus on human gene association studies and systems controlling food intake

scientific article

Motivation for sucrose in sated rats is predicted by low anxiety-like behavior

scientific article

NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition

scientific article published on 16 December 2016

Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans

scientific article

New melanocortin 1 receptor binding motif based on the C-terminal sequence of alpha-melanocyte-stimulating hormone

scientific article published in October 2006

Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship

scientific article

Nitric oxide mediates leptin-induced preovulatory luteinizing hormone and prolactin surges in rats ⬇️

scientific article published on December 27, 2001

Normalization of circulating leptin levels by fasting improves the reproductive function in obese OLETF female rats

scientific article published in February 2001

Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents

scientific article

Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions

scientific article (publication date: 20 November 2002)

Novel selective melanocortin 4 receptor antagonist induces food intake after peripheral administration

scientific article

Obsessive-compulsivity and working memory are associated with differential prefrontal cortex and insula activation in adolescents with a recent diagnosis of an eating disorder

scientific article

One melanocortin 4 and two melanocortin 5 receptors from zebrafish show remarkable conservation in structure and pharmacology

scientific article

Opioids as facilitators of feeding: can any food be rewarding?

scientific article published on 28 April 2011

Orexigenic effect of the melanocortin MC4 receptor antagonist HS014 is inhibited only partially by neuropeptide Y Y1 receptor selective antagonists

scientific article published in February 2000

Origin of the prolactin-releasing hormone (PRLH) receptors: evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution

scientific article

Orphan Drugs and Their Impact on Pharmaceutical Development

article

Orphan Drugs and Their Impact on Pharmaceutical Development: (Trends in Pharmacological Sciences 39, 525-535, 2018)

article

Oxytocin as feeding inhibitor: maintaining homeostasis in consummatory behavior

scientific article

Patients lacking sustainable long-term weight loss after gastric bypass surgery show signs of decreased inhibitory control of prepotent responses

scientific article

Pharmacological characterization of loss of function mutations of the human melanocortin 1 receptor that are associated with red hair

scientific article published in November 2004

Pharmacological characterization of melanocortin receptors in fish suggests an important role for ACTH.

scientific article

Pharmacological comparison of rat and human melanocortin 3 and 4 receptors in vitro

scientific article

Pivotal roles of alpha-melanocyte-stimulating hormone and the melanocortin 4 receptor in leptin stimulation of prolactin secretion in rats

scientific article published in April 2003

Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes

scientific article

Polyunsaturated fatty acids in heart muscle and alpha 1-adrenoceptor binding properties

scientific article published on 01 July 1993

Postnatal profile of plasma leptin concentrations in male and female rats: relation with the maturation of the pituitary-gonadal axis

scientific article

Potato (Solanum tuberosum) juice exerts an anticonvulsant effect in mice through binding to GABA receptors

scientific article

Presence of melanocortin (MC4) receptor in spiny dogfish suggests an ancient vertebrate origin of central melanocortin system

scientific article published on January 2003

Psychological intervention with working memory training increases basal ganglia volume: A VBM study of inpatient treatment for methamphetamine use.

scientific article published on 24 August 2016

Quantitative mapping shows that serotonin rather than dopamine receptor mRNA expressions are affected after repeated intermittent administration of MDMA in rat brain

scientific article published on 3 July 2006

Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies

scientific article published on 02 August 2016

Reduced activity of monoamine oxidase in the rat brain following repeated nandrolone decanoate administration

scientific journal article

Reduced resting-state connectivity in areas involved in processing of face-related social cues in female adolescents with atypical anorexia nervosa

scholarly article by Gaia Olivo et al published 13 December 2018 in Translational Psychiatry

Reduced vasopressin receptors activation mediates the anti-depressant effects of fluoxetine and venlafaxine in bulbectomy model of depression

scientific article published on 23 December 2015

Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor

scientific article published in March 2003

Remarkable similarities between the hemichordate (Saccoglossus kowalevskii) and vertebrate GPCR repertoire ⬇️

scientific article published on May 15, 2013

Remarkable synteny conservation of melanocortin receptors in chicken, human, and other vertebrates ⬇️

scientific article published on May 1, 2003

Repeated intermittent MDMA binges reduce DAT density in mice and SERT density in rats in reward regions of the adolescent brain

scientific article published on 10 July 2007

Replacement of short segments within transmembrane domains of MC2R disrupts retention signal

scientific article

Reply to Braasch and Postlethwait: Evolutionary origin of the teleost A2 agouti genes ( agouti signaling protein 2 and agouti-related protein 2 ) remains unclear ⬇️

scientific article published on March 29, 2011

Response to Leusink et al.

scientific article published in November 2017

Resting-State Brain and the FTO Obesity Risk Allele: Default Mode, Sensorimotor, and Salience Network Connectivity Underlying Different Somatosensory Integration and Reward Processing between Genotypes

scientific article published on 17 February 2016

Resting-state brain connectivity changes in obese women after Roux-en-Y gastric bypass surgery: A longitudinal study

scientific article published on 26 July 2017

Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study

scientific article published on 17 November 2011

Role of MC4 receptors in the depressor and bradycardic effects of α-MSH in the nucleus tractus solitarii of the rat ⬇️

scientific article published on April 15, 2003

Roles of the melanocortin-4 receptor in antipyretic and hyperthermic actions of centrally administered alpha-MSH.

scientific article published on March 2004

Roux-en Y gastric bypass surgery induces genome-wide promoter-specific changes in DNA methylation in whole blood of obese patients

scientific article

SPRIT: Identifying horizontal gene transfer in rooted phylogenetic trees

scientific article

Scrutinizing the FTO locus: compelling evidence for a complex, long-range regulatory context

scientific article

Selective antagonist for the melanocortin 4 receptor (HS014) increases food intake in free-feeding rats

scientific article published on 01 April 1998

Selective properties of C- and N-terminals and core residues of the melanocyte-stimulating hormone on binding to the human melanocortin receptor subtypes ⬇️

scientific article published on May 22, 1998

Selective serotonin reuptake inhibitor (fluoxetine) decreases the effects of ghrelin on memory retention and food intake

scientific article

Selectivity of Cyclic [d-Nal7] and [d-Phe7] Substituted MSH Analogues for the Melanocortin Receptor Subtypes ⬇️

scientific article published on January 1, 1997

Selectivity of [Phe-I7], [Ala6], and [D-Ala4,Gln5,Tyr6] substituted ACTH(4-10) analogues for the melanocortin receptors

scientific article published on 01 January 1997

Self-reported sleep disturbance is associated with Alzheimer's disease risk in men.

scientific article published on 27 October 2014

Sensitization to nicotine significantly decreases expression of GABA transporter GAT-1 in the medial prefrontal cortex

scientific article published on 20 May 2008

Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives

scientific article (publication date: 20 November 2003)

Sex matters: Report experimenter gender

scientific article

Short Sleep Makes Declarative Memories Vulnerable to Stress in Humans

scientific article

Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals

scholarly article by Ilze Elbere published in December 2018

Sleep restriction alters plasma endocannabinoids concentrations before but not after exercise in humans

scientific article published on 22 September 2016

Stimulation of prolactin secretion by chronic, but not acute, administration of leptin in the rat.

scientific article published on December 2000

Structural diversity of G protein-coupled receptors and significance for drug discovery

scientific article (publication date: April 2008)

Structural study of melanocortin peptides by fluorescence spectroscopy: identification of beta-(2-naphthyl)-D-alanine as a fluorescent probe

scientific article published in September 2003

Subliminal food images compromise superior working memory performance in women with restricting anorexia nervosa

scientific article published on 11 March 2012

Subliminal versus supraliminal stimuli activate neural responses in anterior cingulate cortex, fusiform gyrus and insula: a meta-analysis of fMRI studies

scientific article

Subtype selective binding properties of substituted linear melanocyte stimulating hormone analogues

scientific article

Subtype-specific pharmacological properties of the melanocortin receptors in chicken

scientific article

Sweet taste perception not altered after acute sleep deprivation in healthy young men

scientific article published on 30 May 2013

The Adhesion GPCR GPR125 is specifically expressed in the choroid plexus and is upregulated following brain injury

scientific article

The Drosophila small GTPase Rac2 is required for normal feeding and mating behaviour

scientific article published in February 2014

The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus

scientific article

The G protein-coupled receptor subset of the chicken genome

scientific article published in June 2006

The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents

scientific article

The G protein-coupled receptor subset of the rat genome

scientific article

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

scientific article (publication date: June 2003)

The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals

scientific article

The GRAFS classification system of G-protein coupled receptors in comparative perspective

scientific article

The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children

scientific article

The Obesity-Linked Gene Nudt3 Drosophila Homolog Aps Is Associated With Insulin Signaling

scientific article

The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi ⬇️

scientific article published on January 4, 2012

The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake

scientific article published on 5 June 2015

The Role of FTO and Vitamin D for the Weight Loss Effect of Roux-en-Y Gastric Bypass Surgery in Obese Patients

scientific article

The Role of Working Memory for Cognitive Control in Anorexia Nervosa versus Substance Use Disorder

scientific article published on 22 September 2017

The STK33-linked SNP rs4929949 is associated with obesity and BMI in two independent cohorts of Swedish and Greek children

scientific article (publication date: 2013)

The Solute Carrier Families Have a Remarkably Long Evolutionary History with the Majority of the Human Families Present before Divergence of Bilaterian Species ⬇️

scientific article published on December 24, 2010

The adhesion GPCRs: a unique family of G protein-coupled receptors with important roles in both central and peripheral tissues

scientific article

The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors

scientific article

The anabolic androgenic steroid nandrolone decanoate affects mRNA expression of dopaminergic but not serotonergic receptors

scientific journal article

The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924.

scientific article

The dispanins: a novel gene family of ancient origin that contains 14 human members

scientific article published in 2012

The druggable genome: Evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication

scientific article published on 30 August 2013

The early origin of melanocortin receptors, agouti-related peptide, agouti signalling peptide, and melanocortin receptor-accessory proteins, with emphasis on pufferfishes, elephant shark, lampreys, and amphioxus ⬇️

scientific article published on January 3, 2011

The evolutionary history and tissue mapping of GPR123: specific CNS expression pattern predominantly in thalamic nuclei and regions containing large pyramidal cells

scientific article

The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men

scientific article

The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptors

scientific article

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors

scientific article

The impact of cognitive training in substance use disorder: the effect of working memory training on impulse control in methamphetamine users

scientific article

The impact of intronic single nucleotide polymorphisms and ethnic diversity for studies on the obesity gene FTO.

scientific article published on 29 August 2012

The influence of active and passive smoking during pregnancy on umbilical cord blood levels of vitamins A and E and neonatal anthropometric indices

scientific article published on 3 January 2012

The melanin-concentrating hormone receptor 2 (MCH-R2) mediates the effect of MCH to control body color for background adaptation in the barfin flounder

scientific article

The melanocortin 1, 3, 4 or 5 receptors do not have a binding epitope for ACTH beyond the sequence of alpha-MSH ⬇️

scientific article published on October 1, 1997

The melanocortin 4 receptor mediates leptin stimulation of luteinizing hormone and prolactin surges in steroid-primed ovariectomized rats

scientific article

The melanocortin receptor subtypes in chicken have high preference to ACTH-derived peptides

scientific article

The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs

scientific article published on 23 December 2003

The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain

scientific article

The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children

scientific article

The phylogenetic relationship of the glutamate and pheromone G-protein-coupled receptors in different vertebrate species

scientific article

The physiological role of melanocortin receptors

scientific article

The relative impact of chronic food restriction and acute food deprivation on plasma hormone levels and hypothalamic neuropeptide expression

scientific article published on 4 May 2008

The repertoire of G-protein-coupled receptors in fully sequenced genomes

scientific article published in February 2005

The repertoire of trace amine G-protein-coupled receptors: large expansion in zebrafish

scientific article

The role of G protein-coupled receptors in the early evolution of neurotransmission and the nervous system

scientific article

The role of hypothalamic peptide gene expression in alcohol self-administration behavior

scientific article

The role of melanocortin receptors in sexual behavior in female rats

scientific article published on 01 June 2000

The role of the melanocortin system and the melanocortin-4 receptor in ring dove (Streptopelia risoria) feeding behavior

scientific article published in January 2003

There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini

scientific article

Thinking about eating food activates visual cortex with reduced bilateral cerebellar activation in females with anorexia nervosa: an fMRI study

scientific article

To press or not to press? Differential receptor expression and response to novelty in rats learning an operant response for reward

scientific article published on 20 September 2006

Tonic inhibition of food intake during inactive phase is reversed by the injection of the melanocortin receptor antagonist into the paraventricular nucleus of the hypothalamus and central amygdala of the rat.

scientific article published in December 2000

Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome

scientific article

Trends in the exploitation of novel drug targets ⬇️

scientific article published on August 1, 2011

Two hours of evening reading on a self-luminous tablet vs. reading a physical book does not alter sleep after daytime bright light exposure

scientific article published on 25 July 2016

Unusual genomic structure: melanocortin receptors in Fugu

scientific article published in April 2005

Watching TV and food intake: the role of content

scientific article

What model organisms and interactomics can reveal about the genetics of human obesity

scientific article published on 23 May 2012

Withdrawal from free-choice high-fat high-sugar diet induces craving only in obesity-prone animals

scientific article published on 11 February 2009

[]RS79948-197 binding to human, rat, guinea pig and pig α2A-, α2B- and α2C-adrenoceptors. Comparison with MK912, RX821002, rauwolscine and yohimbine ⬇️

scientific article published on February 5, 1998

mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts

scientific article published on 28 January 2016

microRNA-192 suppresses the expression of the farnesoid X receptor

scientific article published on 14 April 2016

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