List of works - Laura Santambrogio

3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine

scientific article published on 21 July 2021

A monoclonal antibody to Histoplasma capsulatum alters the intracellular fate of the fungus in murine macrophages

scientific article

A mutation within the transmembrane domain of melanosomal protein Silver (Pmel17) changes lumenal fragment interactions

scientific article published on 12 August 2009

Age-related carbonylation of fibrocartilage structural proteins drives tissue degenerative modification

scientific article published on July 2013

Age-related oxidative stress compromises endosomal proteostasis

scientific article

Amelioration of proteolipid protein 139-151-induced encephalomyelitis in SJL mice by modified amino acid copolymers and their mechanisms

scholarly article

An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma.

scientific article

Annexin A2 promotes phagophore assembly by enhancing Atg16L⁺ vesicle biogenesis and homotypic fusion

scientific article

Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages

scientific article

Autoimmune response to transthyretin in juvenile idiopathic arthritis

scientific article published on 25 February 2016

CD4-specific transgenic expression of human cyclin T1 markedly increases human immunodeficiency virus type 1 (HIV-1) production by CD4+ T lymphocytes and myeloid cells in mice transgenic for a provirus encoding a monocyte-tropic HIV-1 isolate

scientific article

Carrying yourself: self antigen composition of the lymphatic fluid.

scientific article

Caspases and nitric oxide broadly regulate dendritic cell maturation and surface expression of class II MHC proteins

scientific article

Conformational variation of surface class II MHC proteins during myeloid dendritic cell differentiation accompanies structural changes in lysosomal MIIC.

scientific article published on October 2005

Consequences of metabolic and oxidative modifications of cartilage tissue

scientific article

Contribution of the plasma and lymph Degradome and Peptidome to the MHC Ligandome

scientific article published on 20 October 2018

Copolymer effects on microglia and T cells in the central nervous system of humanized mice

scientific article published in December 2005

Correction: Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis.

scientific article published on 13 March 2008

Correction: Use of extracellular vesicles from lymphatic drainage as surrogate markers of melanoma progression and mutation

scholarly article by Susana García-Silva et al published 6 May 2019 in Journal of Experimental Medicine

Corrigendum: Annexin A2 promotes phagophore assembly by enhancing Atg16⁺ vesicle biogenesis and homotypic fusion

scientific article published on 30 March 2015

Disruption of Multivesicular Body Vesicles Does Not Affect Major Histocompatibility Complex (MHC) Class II-Peptide Complex Formation and Antigen Presentation by Dendritic Cells* ⬇️

scientific article published on July 11, 2013

Endosomal damage and TLR2 mediated inflammasome activation by alkane particles in the generation of aseptic osteolysis

scientific article published on 4 October 2009

Functional analysis of monocyte MHC class II compartments

scientific article published on 24 September 2008

GMCSF in the absence of other cytokines sustains human dendritic cell precursors with T cell regulatory activity and capacity to differentiate into functional dendritic cells

scientific article published on 10 December 2007

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

Hydrodynamic size-based separation and characterization of protein aggregates from total cell lysates

scientific article published on 18 December 2014

IFN regulatory factor-1 regulates IFN-gamma-dependent cathepsin S expression

scientific article

Immunogenecity of modified alkane polymers is mediated through TLR1/2 activation

scientific article

Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage

scientific article published on 20 August 2013

Intralymphatic CCL21 Promotes Tissue Egress of Dendritic Cells through Afferent Lymphatic Vessels

scientific article published on 10 February 2016

Kupffer Cell Transplantation in Mice for Elucidating Monocyte/Macrophage Biology and for Potential in Cell or Gene Therapy

scientific article published on 7 January 2016

Ligand exchange of major histocompatibility complex class II proteins is triggered by H-bond donor groups of small molecules

scientific article

Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging

scientific article

Lymph formation, composition and circulation: a proteomics perspective

scientific article published on 18 March 2015

Lymphatic Cannulation for Lymph Sampling and Molecular Delivery

scientific article published on 13 September 2019

MHC class II compartment subtypes: structure and function

scientific article

Mediators of the inflammatory response to joint replacement devices

scientific article published on 06 September 2011

Methamphetamine enhances histoplasmosis by immunosuppression of the host.

scientific article published in July 2009

Methamphetamine inhibits antigen processing, presentation, and phagocytosis

scientific article

Microautophagy of Cytosolic Proteins by Late Endosomes

Microautophagy of cytosolic proteins by late endosomes

scientific journal article

Modified amino acid copolymers suppress myelin basic protein 85-99-induced encephalomyelitis in humanized mice through different effects on T cells

scholarly article

Molecular Interaction and Enzymatic Activity of Macrophage Migration Inhibitory Factor with Immunorelevant Peptides ⬇️

scientific article published in Journal of Biological Chemistry

Molecular definitions of autophagy and related processes.

scientific article published on 08 June 2017

Monoclonal antibodies specific for the empty conformation of HLA-DR1 reveal aspects of the conformational change associated with peptide binding

scientific article published on 2 February 2004

NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release

scientific article published on 2 November 2017

Neuroprotection and remyelination after autoimmune demyelination in mice that inducibly overexpress CXCL1

scientific article

Novel synthetic amino acid copolymers that inhibit autoantigen-specific T cell responses and suppress experimental autoimmune encephalomyelitis

scientific article

Optimizing dynamic interactions between a cardiac patch and inflammatory host cells

scientific article published on 12 October 2011

Oxidative stress, inflamm-aging and immunosenescence

scientific article published on 21 June 2011

Patterns of expression of factor VIII and von Willebrand factor by endothelial cell subsets in vivo

scientific article published on 12 May 2016

Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation

scientific article published on 05 February 2020

Protein expression profiles of human lymph and plasma mapped by 2D-DIGE and 1D SDS–PAGE coupled with nanoLC–ESI–MS/MS bottom-up proteomics ⬇️

scientific article published on November 30, 2012

Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism

scientific article

Role of Carbonyl Modifications on Aging-Associated Protein Aggregation

scientific article published on 18 January 2016

Short communication: Methamphetamine treatment increases in vitro and in vivo HIV replication

scientific article

Structural and Biological Interaction of hsc-70 Protein with Phosphatidylserine in Endosomal Microautophagy

scientific article published on 12 July 2016

The Antigen Processing and Presentation Machinery in Lymphatic Endothelial Cells

The Lymphatic Fluid

scientific article published on 3 February 2018

The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation

scientific article

The annexin A2/S100A10 system in health and disease: emerging paradigms

scientific article

The ins and outs of MHC class II proteins in dendritic cells

scientific article published on December 2006

The lipid kinase PI4KIIIβ preserves lysosomal identity

scientific article

The lymph as a pool of self-antigens

scientific article published on December 2010

The lymph self-antigen repertoire

scientific article published on 16 December 2013

The melting pot of the MHC II peptidome

scientific article

The scavenger receptor MARCO mediates cytoskeleton rearrangements in dendritic cells and microglia.

scientific article

Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection

scientific article published on 17 June 2021

Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients

scientific article published on 11 April 2019

Whole Chromosome Instability induces senescence and promotes SASP.

scientific article published on 12 October 2016

List of works by Laura Santambrogio

3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine

A monoclonal antibody to Histoplasma capsulatum alters the intracellular fate of the fungus in murine macrophages

A mutation within the transmembrane domain of melanosomal protein Silver (Pmel17) changes lumenal fragment interactions

Age-related carbonylation of fibrocartilage structural proteins drives tissue degenerative modification

Age-related oxidative stress compromises endosomal proteostasis

Amelioration of proteolipid protein 139-151-induced encephalomyelitis in SJL mice by modified amino acid copolymers and their mechanisms

An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma.

Annexin A2 promotes phagophore assembly by enhancing Atg16L⁺ vesicle biogenesis and homotypic fusion

Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages

Autoimmune response to transthyretin in juvenile idiopathic arthritis

CD4-specific transgenic expression of human cyclin T1 markedly increases human immunodeficiency virus type 1 (HIV-1) production by CD4+ T lymphocytes and myeloid cells in mice transgenic for a provirus encoding a monocyte-tropic HIV-1 isolate

Carrying yourself: self antigen composition of the lymphatic fluid.

Caspases and nitric oxide broadly regulate dendritic cell maturation and surface expression of class II MHC proteins

Conformational variation of surface class II MHC proteins during myeloid dendritic cell differentiation accompanies structural changes in lysosomal MIIC.

Consequences of metabolic and oxidative modifications of cartilage tissue

Contribution of the plasma and lymph Degradome and Peptidome to the MHC Ligandome

Copolymer effects on microglia and T cells in the central nervous system of humanized mice

Correction: Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis.

Correction: Use of extracellular vesicles from lymphatic drainage as surrogate markers of melanoma progression and mutation

Corrigendum: Annexin A2 promotes phagophore assembly by enhancing Atg16⁺ vesicle biogenesis and homotypic fusion

Disruption of Multivesicular Body Vesicles Does Not Affect Major Histocompatibility Complex (MHC) Class II-Peptide Complex Formation and Antigen Presentation by Dendritic Cells* ⬇️

Endosomal damage and TLR2 mediated inflammasome activation by alkane particles in the generation of aseptic osteolysis

Functional analysis of monocyte MHC class II compartments

GMCSF in the absence of other cytokines sustains human dendritic cell precursors with T cell regulatory activity and capacity to differentiate into functional dendritic cells

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Hydrodynamic size-based separation and characterization of protein aggregates from total cell lysates

IFN regulatory factor-1 regulates IFN-gamma-dependent cathepsin S expression

Immunogenecity of modified alkane polymers is mediated through TLR1/2 activation

Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage

Intralymphatic CCL21 Promotes Tissue Egress of Dendritic Cells through Afferent Lymphatic Vessels

Kupffer Cell Transplantation in Mice for Elucidating Monocyte/Macrophage Biology and for Potential in Cell or Gene Therapy

Ligand exchange of major histocompatibility complex class II proteins is triggered by H-bond donor groups of small molecules

Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging

Lymph formation, composition and circulation: a proteomics perspective

Lymphatic Cannulation for Lymph Sampling and Molecular Delivery

MHC class II compartment subtypes: structure and function

Mediators of the inflammatory response to joint replacement devices

Methamphetamine enhances histoplasmosis by immunosuppression of the host.

Methamphetamine inhibits antigen processing, presentation, and phagocytosis

Microautophagy of Cytosolic Proteins by Late Endosomes

Microautophagy of cytosolic proteins by late endosomes

Modified amino acid copolymers suppress myelin basic protein 85-99-induced encephalomyelitis in humanized mice through different effects on T cells

Molecular Interaction and Enzymatic Activity of Macrophage Migration Inhibitory Factor with Immunorelevant Peptides ⬇️

Molecular definitions of autophagy and related processes.

Monoclonal antibodies specific for the empty conformation of HLA-DR1 reveal aspects of the conformational change associated with peptide binding

NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release

Neuroprotection and remyelination after autoimmune demyelination in mice that inducibly overexpress CXCL1

Novel synthetic amino acid copolymers that inhibit autoantigen-specific T cell responses and suppress experimental autoimmune encephalomyelitis

Optimizing dynamic interactions between a cardiac patch and inflammatory host cells

Oxidative stress, inflamm-aging and immunosenescence

Patterns of expression of factor VIII and von Willebrand factor by endothelial cell subsets in vivo

Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation

Protein expression profiles of human lymph and plasma mapped by 2D-DIGE and 1D SDS–PAGE coupled with nanoLC–ESI–MS/MS bottom-up proteomics ⬇️

Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism

Role of Carbonyl Modifications on Aging-Associated Protein Aggregation

Short communication: Methamphetamine treatment increases in vitro and in vivo HIV replication

Structural and Biological Interaction of hsc-70 Protein with Phosphatidylserine in Endosomal Microautophagy

The Antigen Processing and Presentation Machinery in Lymphatic Endothelial Cells

The Lymphatic Fluid

The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation

The annexin A2/S100A10 system in health and disease: emerging paradigms

The ins and outs of MHC class II proteins in dendritic cells

The lipid kinase PI4KIIIβ preserves lysosomal identity

The lymph as a pool of self-antigens

The lymph self-antigen repertoire

The melting pot of the MHC II peptidome

The scavenger receptor MARCO mediates cytoskeleton rearrangements in dendritic cells and microglia.

Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection

Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients

Whole Chromosome Instability induces senescence and promotes SASP.