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Authors whose works are in public domain in at least one jurisdiction

List of works by Gian Maria Fimia

14th Euroconference on Apoptosis: ‘death or survival? Fate in Sardinia’

scientific article published on 25 May 2007

A TRIM32-AMBRA1-ULK1 complex initiates the autophagy response in atrophic muscle cells

scientific article published on 28 June 2019

A new transcriptional repressor of the pseudomonas aeruginosa quorum sensing receptor gene lasR

scientific article

A novel role for autophagy in neurodevelopment

scientific article published on 21 June 2007

AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis

scientific article published on 01 December 2018

AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamics

scientific article published on 11 December 2014

AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1

scientific article

AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1.

scientific article published on March 2015

AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation

scientific article published on December 2014

AMBRA1, a novel α-synuclein-binding protein, is implicated in the pathogenesis of multiple system atrophy.

scientific article published on 22 November 2016

AMBRA1-regulated autophagy in vertebrate development

scientific article

Activation of Vgamma9Vdelta2 T cells by non-peptidic antigens induces the inhibition of subgenomic HCV replication

scientific article published on 16 December 2005

Ambra1 at the crossroad between autophagy and cell death ⬇️

scientific article published on October 15, 2012

Ambra1 knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis

scientific article published on 24 January 2013

Ambra1 regulates autophagy and development of the nervous system

scientific article

An immunosurveillance mechanism controls cancer cell ploidy

scientific article

Analysis of Secreted Proteins from Prepubertal Ovarian Tissues Exposed In Vitro to Cisplatin and LH

scientific article published on 03 April 2022

Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen

scientific article

Antitubercular and anti-inflammatory properties screening of natural products from Plectranthus species

scientific article published on 29 June 2018

Autophagy in HCV infection: keeping fat and inflammation at bay

scientific article

Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains

scientific article published on 08 May 2019

Autophagy plays an important role in the containment of HIV-1 in nonprogressor-infected patients.

scientific article

Autophagy protects cells from HCV-induced defects in lipid metabolism

scientific article

Autophagy regulates hepatocyte identity and epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions promoting Snail degradation

scientific article published on 10 September 2015

Beclin1: a role in membrane dynamics and beyond

scientific article published on January 2012

CREM-dependent transcription in male germ cells controlled by a kinesin.

scientific article

Calreticulin exposure dictates the immunogenicity of cancer cell death

scientific article

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

scientific article

Clinical isolates of the modern Mycobacterium tuberculosis lineage 4 evade host defense in human macrophages through eluding IL-1β-induced autophagy.

scientific article published on 24 May 2018

Conventional protein kinase C inhibition prevents alpha interferon-mediated hepatitis C virus replicon clearance by impairing STAT activation

scientific article published on December 2004

Dendritic cells activation is associated with sustained virological response to telaprevir treatment of HCV-infected patients.

scientific article

Dismantling the autophagic arsenal when it is time to die

scientific article published on 11 May 2012

Double-stranded internucleosomal cleavage of apoptotic DNA is dependent on the degree of differentiation in muscle cells.

scientific article published on June 1996

Downregulation of E2F1 during ER stress is required to induce apoptosis.

scientific article published on 22 January 2015

EBV stimulates TLR‐ and autophagy‐dependent pathways and impairs maturation in plasmacytoid dendritic cells: Implications for viral immune escape ⬇️

scientific article published on October 30, 2012

ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells

scientific article

Effective Synergy of Sorafenib and Nutrient Shortage in Inducing Melanoma Cell Death through Energy Stress

scientific article published on 06 March 2020

Emerging Mechanisms in Initiating and Terminating Autophagy.

scientific article

Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell Fate

scientific article

Erratum: Corrigendum: AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation

scholarly article published in Nature Cell Biology

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

scientific article

Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19)

scientific article published on 08 June 2020

Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection

scientific article

Fasting boosts sensitivity of human skin melanoma to cisplatin-induced cell death.

scientific article published on 28 September 2016

Fateful music from a talented orchestra with a wicked conductor: Connection between oncogenic BRAF, ER stress, and autophagy in human melanoma.

scientific article

Fenretinide induces autophagic cell death in caspase-defective breast cancer cells.

scientific article published on 4 February 2008

Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation.

scientific article

First description of agonist and antagonist IP-10 in urine of patients with active TB

scientific article published on 07 September 2018

Glucose capped silver nanoparticles induce cell cycle arrest in HeLa cells

scientific article published on 18 February 2017

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HPV sensitizes OPSCC cells to cisplatin-induced apoptosis by inhibiting autophagy through E7-mediated degradation of AMBRA1

scientific article published on 10 November 2020

Hepatitis C virus relies on lipoproteins for its life cycle

scientific article

Histological and proteomic profile of diabetic versus non-diabetic dilated cardiomyopathy

scientific article published on 20 October 2015

IP-10 contributes to the inhibition of mycobacterial growth in an ex vivo whole blood assay

scientific article published on 22 May 2019

Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD.

scientific article published on 17 April 2014

Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance

scientific journal article

Inhibition of HIV-1 replication in monocyte-derived macrophages by Mycobacterium tuberculosis

scientific article published on 4 February 2004

Inhibition of autophagy in EBV-positive Burkitt's lymphoma cells enhances EBV lytic genes expression and replication.

scientific article published on 3 September 2015

Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis

scientific article published on 21 May 2015

Interplay between autophagy and apoptosis in the development of Danio rerio follicles and the effects of a probiotic

scientific article published in January 2013

Iron overload down-regulates the expression of the HIV-1 Rev cofactor eIF5A in infected T lymphocytes

scientific article published on 04 August 2017

Liver protein profiling in chronic hepatitis C: identification of potential predictive markers for interferon therapy outcome

scientific article published on 7 December 2011

Lysyl tRNA synthetase is required for the translocation of calreticulin to the cell surface in immunogenic death

scientific article

Methods to Study the BECN1 Interactome in the Course of Autophagic Responses.

scientific article published on 15 December 2016

Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy

scientific article

Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases

scientific article

Molecular definitions of autophagy and related processes.

scientific article published on 08 June 2017

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

Molecular mechanisms of hepatitis C virus-induced hepatocellular carcinoma

scientific article

Molecular mechanisms of selective autophagy ⬇️

scientific article published on January 1, 2013

Murine hepatocyte cell lines promote expansion and differentiation of NK cells from stem cell precursors

scientific article published on June 2004

Mycobacterium tuberculosis-induced miR-155 subverts autophagy by targeting ATG3 in human dendritic cells.

scientific article published on 4 January 2018

Negative regulation of MAVS-mediated antiviral signaling by the mitochondrial protein LRPPRC during HCV infection

scientific article published on 18 December 2018

Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytes

scientific article published on 24 May 2011

On-target versus off-target effects of drugs inhibiting the replication of SARS-CoV-2

scientific article published on 19 August 2020

Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition.

scientific article published on 26 January 2011

Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma

scientific article

Optimization of the autophagy measurement in a human cell line and primary cells by flow cytometry

scientific article published on 26 June 2019

Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells

scientific article published on 7 June 2016

PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation

scientific article published on 17 February 2017

Production of fertile offspring from genetically infertile male mice

scientific journal article

Prosurvival AMBRA1 turns into a proapoptotic BH3-like protein during mitochondrial apoptosis

scientific article published on 28 April 2016

Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response.

scientific article published on 23 March 2012

Proteomic analysis identifies prohibitin down-regulation as a crucial event in the mitochondrial damage observed in HIV-infected patients

scientific article

Proteomic analysis of anti-angiogenic effects by a combined treatment with vinblastine and rapamycin in an endothelial cell line.

scientific article published in August 2006

Proteomic analysis of human very low-density lipoprotein by two-dimensional gel electrophoresis and MALDI-TOF/TOF

scientific article

Proteomic analysis reveals a major role for contact inhibition in the terminal differentiation of hepatocytes

scientific article

Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs

scientific article published on 09 October 2020

Regulation of autophagy in mammals and its interplay with apoptosis.

scientific article published on 18 February 2010

Reticulon protein-1C is a key component of MAMs

scientific article published on 5 January 2015

Role of autophagy in HIV infection and pathogenesis

scientific article published on 31 January 2017

Rose Bengal acetate photodynamic therapy (RBAc-PDT) induces exposure and release of Damage-Associated Molecular Patterns (DAMPs) in human HeLa cells

scientific article (publication date: 2014)

Signaling routes to CREM and CREB: plasticity in transcriptional activation.

scientific article

Specific T Cells Restore the Autophagic Flux Inhibited by Mycobacterium tuberculosis in Human Primary Macrophages

scientific article published on 28 March 2012

TG2 regulates the heat-shock response by the post-translational modification of HSF1

scientific article published on 11 May 2018

TRIM proteins in autophagy: selective sensors in cell damage and innate immune responses

scientific article published on 22 January 2020

TRIM50 regulates Beclin 1 proautophagic activity.

scientific article published on 28 March 2018

Temporal regulation of autophagy response by the CULLIN 4-AMBRA1-CULLIN 5 axis.

scientific article published on 3 February 2015

The Activity of Differentiation Factors Induces Apoptosis in Polyomavirus Large T-Expressing Myoblasts ⬇️

scientific article published on June 1, 1998

The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

scientific article

The involvement of cell death and survival in neural tube defects: a distinct role for apoptosis and autophagy?

scientific article published on 02 May 2008

The rate of aneuploidy is altered in spermatids from infertile mice.

scientific article

The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy

scientific article

The transglutaminase type 2 and pyruvate kinase isoenzyme M2 interplay in autophagy regulation.

scientific article published on 24 December 2015

Tissue transglutaminase is a multifunctional BH3-only protein

scientific article published on 12 October 2004

Toward the understanding of autophagy regulation and its interplay with cell death pathways

scientific article published on 01 July 2009

Transcriptional Control in Male Germ Cells: General Factor TFIIA Participates in CREM-Dependent Gene Activation ⬇️

scientific article published on September 25, 2003

Transcriptional control of the pvdS iron starvation sigma factor gene by the master regulator of sulfur metabolism CysB in Pseudomonas aeruginosa

scientific journal article

Transglutaminase 2 ablation leads to defective function of mitochondrial respiratory complex I affecting neuronal vulnerability in experimental models of extrapyramidal disorders.

scientific article

Transglutaminase 2 ablation leads to mitophagy impairment associated with a metabolic shift towards aerobic glycolysis.

scientific article published on 25 July 2014

Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75

scientific article published on 01 December 2018

Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates

scientific article published on 05 March 2021

Transglutaminase type 2-dependent selective recruitment of proteins into exosomes under stressful cellular conditions.

scientific article published on 8 May 2016

Transglutaminase type II plays a protective role in hepatic injury

scientific article published on April 2003

Unleashing the Ambra1-Beclin 1 complex from dynein chains: Ulk1 sets Ambra1 free to induce autophagy

scientific article

Why is autophagy important for melanoma? Molecular mechanisms and therapeutic implications ⬇️

scientific article published on July 12, 2013

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.

scientific article published on 24 March 2013

“Tissue” transglutaminase contributes to the formation of disulphide bridges in proteins of mitochondrial respiratory complexes

scientific article published on 03 August 2006

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