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List of works by Lars Bolund

A Sleeping Beauty DNA transposon-based genetic sensor for functional screening of vitamin D3 analogues

scientific article

A lentiviral vector-based genetic sensor system for comparative analysis of permeability and activity of vitamin D3 analogues in xenotransplanted human skin

scientific article published on March 2013

A microarray analysis of the rice transcriptome and its comparison to Arabidopsis

scientific article

A population threshold for functional polymorphisms

scientific article

An improved PCR strategy for fast screening of specific and random integrations in rAAV-mediated gene targeted cell clones ⬇️

scientific article published on July 21, 2011

An improved method for genome wide DNA methylation profiling correlated to transcription and genomic instability in two breast cancer cell lines

scientific article

An update on targeted gene repair in mammalian cells: methods and mechanisms ⬇️

scientific article published on 02 February 2011

Analyses of pig genomes provide insight into porcine demography and evolution

scientific article

Are keratoacanthomas variants of squamous cell carcinomas? A comparison of chromosomal aberrations by comparative genomic hybridization

scientific article published on 25 May 2006

Array Comparative Genomic Hybridization of Keratoacanthomas and Squamous Cell Carcinomas: Different Patterns of Genetic Aberrations Suggest Two Distinct Entities ⬇️

scientific article published on April 26, 2012

Aseptic minimum volume vitrification technique for porcine parthenogenetically activated blastocyst

scientific article published on January 1, 2011

Association of chromosome 19q13.2-3 haplotypes with basal cell carcinoma: tentative delineation of an involved region using data for single nucleotide polymorphisms in two cohorts

scientific article

BS-SNPer: SNP calling in bisulfite-seq data

scientific article

Building the sequence map of the human pan-genome

scientific article

Clinical outcome of preimplantation genetic diagnosis and screening using next generation sequencing

scientific article

Comparison of gene expression and genome-wide DNA methylation profiling between phenotypically normal cloned pigs and conventionally bred controls

scientific article

Computational Methods for Epigenetic Analysis: The Protocol of Computational Analysis for Modified Methylation-Specific Digital Karyotyping Based on Massively Parallel Sequencing ⬇️

scientific article published on January 1, 2011

DNA copy number aberrations in breast cancer by array comparative genomic hybridization

scientific article published on June 2009

DNA methylation in peripheral blood cells of pigs cloned by somatic cell nuclear transfer

scientific article

De novo assembly of a haplotype-resolved human genome.

scientific article

Development of transgenic minipigs with expression of antimorphic human cryptochrome 1

scientific article

Elevated NaCl concentration improves cryotolerance and developmental competence of porcine oocytes

scientific article published on March 2009

Epidermolysis bullosa simplex keratinocytes with extended lifespan established by ectopic expression of telomerase

scientific article published on February 2003

Erratum: The sequence and de novo assembly of the giant panda genome

scientific article published in Nature

Estimation of tumor heterogeneity using CGH array data

scientific article

Exome sequencing identifies somatic point mutations associated with acquired endocrine resistance in breast cancer cell lines

scientific article

Expression and Localization of Peroxisome Proliferator-Activated Receptors and Nuclear Factor κB in Normal and Lesional Psoriatic Skin

Expression of short-chain acyl-CoA dehydrogenase (SCAD) proteins in the liver of SCAD deficient mice after hydrodynamic gene transfer

scientific article published in April 2003

Factors Determining the Efficiency of Porcine Somatic Cell Nuclear Transfer: Data Analysis with Over 200,000 Reconstructed Embryos

scientific article

Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant

scientific article

Gene expression responses to FUS, EWS, and TAF15 reduction and stress granule sequestration analyses identifies FET-protein non-redundant functions

scientific article

Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging).

scientific article published on April 2007

Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA methylation by dCas9 methyltransferases

scientific article published in March 2018

Genomic organization, transcript variants and comparative analysis of the human nucleoporin 155 (NUP155) gene

scientific article (publication date: 17 April 2002)

Genomic structure of the human mitochondrial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter

scientific article

Golden Gate Assembly of CRISPR gRNA expression array for simultaneously targeting multiple genes

scientific article published on 13 May 2016

GxE interactions between FOXO genotypes and drinking tea are significantly associated with prevention of cognitive decline in advanced age in China

scientific article published on 3 June 2014

Handling of human short-chain acyl-CoA dehydrogenase (SCAD) variant proteins in transgenic mice

scientific article

Handmade Cloned Transgenic Piglets Expressing the Nematode Fat-1 Gene ⬇️

scientific article published on June 1, 2012

Haplotype frequencies in a sub-region of chromosome 19q13.3, related to risk and prognosis of cancer, differ dramatically between ethnic groups

scientific article

Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer's disease-causing dominant mutation APPsw

scientific article

High hydrostatic pressure treatment of porcine oocytes before handmade cloning improves developmental competence and cryosurvival

scientific article

High hydrostatic pressure treatment of porcine oocytes induces parthenogenetic activation

scientific article published in August 2010

High-resolution mapping of genotype-phenotype relationships in cri du chat syndrome using array comparative genomic hybridization

scientific article

Identification of genetic aberrations on chromosome 22 outside the NF2 locus in schwannomatosis and neurofibromatosis type 2.

scientific article

Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research

scientific article

Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

scientific article

Interaction Between the FOXO1A-209 Genotype and Tea Drinking Is Significantly Associated with Reduced Mortality at Advanced Ages

scientific article published on 28 September 2015

Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP.

scientific article

Mechanisms underlying targeted gene correction using chimeric RNA/DNA and single-stranded DNA oligonucleotides

scientific article

Mesenchymal stem cells derived from human induced pluripotent stem cells retain adequate osteogenicity and chondrogenicity but less adipogenicity

scientific article published on 18 August 2015

Misfolding, degradation, and aggregation of variant proteins. The molecular pathogenesis of short chain acyl-CoA dehydrogenase (SCAD) deficiency

scientific article published on 23 September 2003

Mosaics and moles

scientific article

Mutation analysis in mitochondrial fatty acid oxidation defects: Exemplified by acyl-CoA dehydrogenase deficiencies, with special focus on genotype-phenotype relationship

scientific article (publication date: September 2001)

Novel loci and pathways significantly associated with longevity

scientific article published on 25 February 2016

Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios ⬇️

scientific article

Omics-based profiling of carcinoma of the breast and matched regional lymph node metastasis

article

Osmotic stress induced by sodium chloride, sucrose or trehalose improves cryotolerance and developmental competence of porcine oocytes

scientific article published on January 2009

Paternal Hemizygosity in 11p15 in Mole-like Conceptuses: Two Case Reports

scientific article

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

scientific article published on 06 February 2017

Pig gene knockout by rAAV-mediated homologous recombination: comparison of BRCA1 gene knockout efficiency in Yucatan and Göttingen fibroblasts with slightly different target sequences.

scientific article

Pig genome sequence--analysis and publication strategy

scientific article published on 19 July 2010

Pig transgenesis by Sleeping Beauty DNA transposition

scientific article

PigGIS: Pig Genomic Informatics System

scientific article

Piglets born from vitrified cloned blastocysts produced with a simplified method of delipation and nuclear transfer

scientific article published on January 2007

Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing

scientific article

Platelet Derived Growth Factor (PDGF) Responsive Epidermis Formed from Human Keratinocytes Transduced with the PDGFβ Receptor Gene ⬇️

scientific article published on May 1, 2003

Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags

scientific article

Production of Pigs by Hand-Made Cloning Using Mesenchymal Stem Cells and Fibroblasts

scientific article published in August 2016

Production of Retroviral Vectors in Primary Human Keratinocytes after DNA-Mediated Gene Transfer Leads to Prolonged Gene Expression ⬇️

scientific article published on January 1, 2003

Production of porcine blastocysts expressed EGFP by handmade cloning

scientific article published in May 2011

Protein misfolding, aggregation, and degradation in disease

scientific article

RNA-Guided Activation of Pluripotency Genes in Human Fibroblasts

scientific article published on June 2017

Rapid genotyping of human ERCC1 exon 4 polymorphism with fluorescence analysis using fluorophore-labeled hybridization probes and a lightcycler

journal article published in 2002

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

SMAP: a streamlined methylation analysis pipeline for bisulfite sequencing

scientific article published on July 2015

SNP genotyping using microsphere-linked PNA and flow cytometric detection

scientific article

SOAPindel: efficient identification of indels from short paired reads

scientific article

Sequencing and de novo assembly of 150 genomes from Denmark as a population reference

scientific article published in Nature

Sequencing bias: comparison of different protocols of MicroRNA library construction

article

Sequencing bias: comparison of different protocols of microRNA library construction

scientific article

Sequencing of 50 human exomes reveals adaptation to high altitude

scientific article

Sex Differences in Genetic Associations With Longevity

Short PNA molecular beacons for real-time PCR allelic discrimination of single nucleotide polymorphisms

scientific article

Side population cells in human and mouse epidermis lack stem cell characteristics

scientific article published in April 2004

Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm

scientific article

Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor

scientific article

Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer

scientific article

Site-specific strand bias in gene correction using single-stranded oligonucleotides

scientific article published on 27 October 2004

Snap: an integrated SNP annotation platform

scientific article published on 29 November 2006

State of the art de novo assembly of human genomes from massively parallel sequencing data

scientific article

Stress for stress tolerance? A fundamentally new approach in mammalian embryology

scientific article published on 10 June 2010

Structural variation in two human genomes mapped at single-nucleotide resolution by whole genome de novo assembly

scientific article

Targeted Genome Editing by Recombinant Adeno-Associated Virus (rAAV) Vectors for Generating Genetically Modified Pigs ⬇️

scientific article published on May 18, 2012

Temporal dissection of tumorigenesis in primary cancers

scientific article

Tetraploidy in hydatidiform moles

scientific article

The ACADS gene variation spectrum in 114 patients with short-chain acyl-CoA dehydrogenase (SCAD) deficiency is dominated by missense variations leading to protein misfolding at the cellular level

scientific article

The DNA methylome of human peripheral blood mononuclear cells

scientific article

The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

scientific article

The diploid genome sequence of an Asian individual

scientific article

The genome of the cucumber, Cucumis sativus L

scientific article

The parental origin correlates with the karyotype of human embryos developing from tripronuclear zygotes

scientific article

The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer

scientific article published on 22 May 2015

The sequence and analysis of a Chinese pig genome

scientific article published on 15 November 2012

The sequence and de novo assembly of the giant panda genome

scientific article

Towards Personalized Regenerative Cell Therapy: Mesenchymal Stem Cells Derived from Human Induced Pluripotent Stem Cells

scientific article published on 23 July 2015

Transgenic Wuzhishan minipigs designed to express a dominant-negative porcine growth hormone receptor display small stature and a perturbed insulin/IGF-1 pathway

scientific article published on 28 October 2015

TreeFam: 2008 Update

scientific article

TreeFam: a curated database of phylogenetic trees of animal gene families

scientific article

Triploid pregnancies: genetic and clinical features of 158 cases

scientific article published on 18 March 2014

Triploidy--Observations in 154 Diandric Cases

scientific article published on 12 November 2015

Tumor heterogeneity in neoplasms of breast, colon, and skin

scientific article

Twelve single nucleotide polymorphisms on chromosome 19q13.2-13.3: linkage disequilibria and associations with basal cell carcinoma in Danish psoriatic patients

scientific article published on February 2003

Twin pregnancies with diploid hydatidiform mole and co-existing normal fetus may originate from one oocyte

scientific article published on 12 June 2008

Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population

scientific article published on 22 January 2014

WEGO 2.0: a web tool for analyzing and plotting GO annotations, 2018 update.

scientific article published in July 2018

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