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List of works by Christopher V Plowe

A Research Agenda to Underpin Malaria Eradication

scientific article

A Single Mutation in K13 Predominates in Southern China and Is Associated With Delayed Clearance of Plasmodium falciparum Following Artemisinin Treatment

scientific article

A comparison of anemia in hemoglobin C and normal hemoglobin A children with Plasmodium falciparum malaria

scientific article published in May 2004

A comprehensive survey of polymorphisms conferring anti-malarial resistance in Plasmodium falciparum across Pakistan

scientific article published on 29 August 2013

A field trial to assess a blood-stage malaria vaccine

scientific article published on September 2011

A high-throughput method for quantifying alleles and haplotypes of the malaria vaccine candidate Plasmodium falciparum merozoite surface protein-1 19 kDa

scientific article

A longitudinal trial comparing chloroquine as monotherapy or in combination with artesunate, azithromycin or atovaquone-proguanil to treat malaria

scientific article

A malaria vaccine for control: more progress

scientific article published in August 2009

A microarray platform and novel SNP calling algorithm to evaluate Plasmodium falciparum field samples of low DNA quantity

scientific article

A network to monitor antimalarial drug resistance: a plan for moving forward

scientific article

A new method for sequencing the hypervariable Plasmodium falciparum gene var2csa from clinical samples

scientific article published on 17 August 2017

An ultrasensitive reverse transcription polymerase chain reaction assay to detect asymptomatic low-density Plasmodium falciparum and Plasmodium vivax infections in small volume blood samples

scientific article

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

scientific article (publication date: 19 July 2012)

Antibodies to Peptides in Semiconserved Domains of RIFINs and STEVORs Correlate with Malaria Exposure

scholarly article by Albert E Zhou et al published 20 March 2019 in mSphere

Antibody Profiling by Proteome Microarray with Multiplex Isotype Detection Reveals Overlap between Human and Aotus nancymaae Controlled Malaria Infections

scholarly article by Omid Taghavian et al published July 2018 in Proteomics

Antibody Profiling by Proteome Microarray with Multiplex Isotype Detection Reveals Overlap between Human and Aotus nancymaae Controlled Malaria Infections.

scientific article published on 19 December 2017

Antigen-Specific B Memory Cell Responses to Plasmodium falciparum Malaria Antigens and Schistosoma haematobium Antigens in Co-Infected Malian Children ⬇️

scientific article published on June 5, 2012

Artemisinin resistance in Myanmar

scientific article published in September 2015

Artemisinin-resistant malaria: research challenges, opportunities, and public health implications

scientific article

Association between the pharmacokinetics and in vivo therapeutic efficacy of sulfadoxine-pyrimethamine in Malawian children

scientific article

Association of Schistosoma haematobium infection with protection against acute Plasmodium falciparum malaria in Malian children.

scientific article published on December 2005

Association of a Novel Mutation in the Plasmodium falciparum Chloroquine Resistance Transporter With Decreased Piperaquine Sensitivity

scientific article published on August 2017

Association of intraleukocytic Plasmodium falciparum malaria pigment with disease severity, clinical manifestations, and prognosis in severe malaria

scientific article published in September 2003

Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection

scientific article published on 21 February 2017

Blood folate concentrations and in vivo sulfadoxine-pyrimethamine failure in Malawian children with uncomplicated Plasmodium falciparum malaria

scientific article

Blood group O protects against severe Plasmodium falciparum malaria through the mechanism of reduced rosetting

scholarly article

Cell-mediated immunity elicited by the blood stage malaria vaccine apical membrane antigen 1 in Malian adults: results of a Phase I randomized trial

scientific article published on 31 January 2009

Children with cerebral malaria or severe malarial anaemia lack immunity to distinct variant surface antigen subsets

scientific article

Chloroquine-azithromycin combination antimalarial treatment decreases risk of respiratory- and gastrointestinal-tract infections in Malawian children

scientific article

Clearance of drug-resistant parasites as a model for protective immunity in Plasmodium falciparum malaria.

scientific article published on November 2003

Clinical manifestations of new versus recrudescent malaria infections following anti-malarial drug treatment

scientific article

Combination therapy for malaria: mission accomplished?

scientific article published on 5 March 2007

Community permission for medical research in developing countries

scientific article published on 7 June 2005

Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites

scientific article

Correction: Variation in the Circumsporozoite Protein of Plasmodium falciparum: Vaccine Development Implications

scientific article published on 28 January 2016

Corrigendum: Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

scientific article published in June 2016

Cotrimoxazole prophylaxis and malaria in Africa: Have the important questions been answered?

scientific article published in September 2006

Defining the in vivo phenotype of artemisinin-resistant falciparum malaria: a modelling approach

scientific article

Designing malaria vaccines to circumvent antigen variability

scientific article published on 13 October 2015

Determinants of treatment response to sulfadoxine-pyrimethamine and subsequent transmission potential in falciparum malaria

scientific article

Development of a metabolically active, non-replicating sporozoite vaccine to prevent Plasmodium falciparum malaria

scientific article

Differential recognition of terminal extracellular Plasmodium falciparum VAR2CSA domains by sera from multigravid, malaria-exposed Malian women

scientific article published on 27 April 2015

Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia

scientific article published on 5 September 2006

Dynamics of polymorphism in a malaria vaccine antigen at a vaccine-testing site in Mali

scientific article

Effects of concomitant Schistosoma haematobium infection on the serum cytokine levels elicited by acute Plasmodium falciparum malaria infection in Malian children

scientific article

Epitope-based sieve analysis of Plasmodium falciparum sequences from a FMP2.1/AS02A vaccine trial is consistent with differential vaccine efficacy against immunologically relevant AMA1 variants

scientific article published on 19 June 2020

Epitope-specific antibody responses to a Plasmodium falciparum subunit vaccine target in a malaria-endemic population

scientific article published on 29 September 2020

Evidence-Based Policies on Migration and Global Health are Essential to Maintain the Health of Those Inside and Outside the United States

scientific article published on January 2017

Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine Resistance

scientific article published on 26 May 2015

Expression of complement and toll-like receptor pathway genes is associated with malaria severity in Mali: a pilot case control study

scientific article published on 9 March 2016

Extended safety, immunogenicity and efficacy of a blood-stage malaria vaccine in malian children: 24-month follow-up of a randomized, double-blinded phase 2 trial

scientific article

Extent and Dynamics of Polymorphism in the Malaria Vaccine Candidate Reticulocyte-Binding Protein Homologue-5 in Kalifabougou, Mali

scholarly article published by Ogobara K. Doumbo in 2018

External quality assurance of malaria nucleic acid testing for clinical trials and eradication surveillance

scientific article (publication date: 2014)

Extreme polymorphism in a vaccine antigen and risk of clinical malaria: implications for vaccine development

scientific article

Genetic architecture of artemisinin-resistant Plasmodium falciparum

scientific article (publication date: March 2015)

Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia

scientific article published on 17 December 2012

Genetics of drug-resistant Plasmodium falciparum malaria in the Venezuelan state of Bolivar

scientific article published on October 2002

Genome-wide and fine-resolution association analysis of malaria in West Africa

scientific article

Genomic epidemiology of the current wave of artemisinin resistant malaria

scholarly article by Roberto Amato et al published 22 May 2015 in bioRxiv

HLA-A2 supertype-restricted cell-mediated immunity by peripheral blood mononuclear cells derived from Malian children with severe or uncomplicated Plasmodium falciparum malaria and healthy controls

scientific article

Hemoglobin C Trait Provides Protection From Clinical Falciparum Malaria in Malian Children

scientific article

High levels of Plasmodium falciparum rosetting in all clinical forms of severe malaria in African children

scientific article

Host and Parasite Transcriptomic Changes upon Successive Plasmodium falciparum Infections in Early Childhood

scientific article published on 07 July 2020

Immunoglobulin G subclass and antibody avidity responses in Malian children immunized with Plasmodium falciparum apical membrane antigen 1 vaccine candidate FMP2.1/AS02

article

Impact of HIV-associated immunosuppression on malaria infection and disease in Malawi

scientific article

Impact of preseason treatment on incidence of falciparum malaria and parasite density at a site for testing malaria vaccines in Bandiagara, Mali.

scientific article published on December 2002

Impact of trimethoprim-sulfamethoxazole prophylaxis on falciparum malaria infection and disease

scientific article published on 13 October 2005

In Memoriam: A Tribute to Alan Magill

scientific article

Incidence of severe Plasmodium falciparum malaria as a primary endpoint for vaccine efficacy trials in Bandiagara, Mali

scientific article published in August 2004

Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia

scientific article

Lack of allele-specific efficacy of a bivalent AMA1 malaria vaccine

scientific article

Limited geographical origin and global spread of sulfadoxine-resistant dhps alleles in Plasmodium falciparum populations

scientific article published on 21 October 2011

Long-term Maintenance of CD4 T Cell Memory Responses to Malaria Antigens in Malian Children Coinfected with Schistosoma haematobium

scientific article published in January 2017

Low infectivity of Plasmodium falciparum gametocytes to Anopheles gambiae following treatment with sulfadoxine-pyrimethamine in Mali ⬇️

scientific article published on 9 May 2010

Low multiplication rates of African Plasmodium falciparum isolates and lack of association of multiplication rate and red blood cell selectivity with malaria virulence

scientific article published on April 2006

Malaria severity: Possible influence of the E670G PCSK9 polymorphism: A preliminary case-control study in Malian children

scientific article published on 15 February 2018

Malaria: Resistance nailed

scientific article published on 18 December 2013

Mechanisms of resistance of malaria parasites to antifolates

scientific article

Microarray analyses reveal strain-specific antibody responses to Plasmodium falciparum apical membrane antigen 1 variants following natural infection and vaccination

scientific article published on 03 March 2020

Molecular basis of allele-specific efficacy of a blood-stage malaria vaccine: vaccine development implications

scientific article published on 29 November 2012

Molecular diagnosis of resistance to antimalarial drugs during epidemics and in war zones

scientific article published on 15 July 2004

Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malaria

scientific article published on 17 January 2002

Monitoring and deterring drug-resistant malaria in the era of combination therapy

scientific article published on December 2007

Monitoring antifolate resistance in intermittent preventive therapy for malaria

scientific article published on 12 August 2013

Monitoring antimalarial drug resistance: making the most of the tools at hand ⬇️

scientific article published on November 1, 2003

Mother-Newborn Pairs in Malawi Have Similar Antibody Repertoires to Diverse Malaria Antigens

scientific article published on 23 August 2017

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

scientific article published on 28 April 2013

New var reconstruction algorithm exposes high var sequence diversity in a single geographic location in Mali

scientific article

Next generation sequencing to detect variation in the Plasmodium falciparum circumsporozoite protein

scientific article published in May 2012

No evidence of delayed parasite clearance after oral artesunate treatment of uncomplicated falciparum malaria in Mali

scientific article

Observational cohort study of HIV-infected African children

scientific article published in July 2006

Optimizing Intradermal Administration of Cryopreserved Plasmodium falciparum Sporozoites in Controlled Human Malaria Infection

scientific article

Ordered Accumulation of Mutations Conferring Resistance to Sulfadoxine-Pyrimethamine in the Plasmodium falciparum Parasite ⬇️

scientific article published on August 6, 2013

Origin and dissemination of Plasmodium falciparum drug-resistance mutations in South America

scientific article published on 9 September 2002

Persistence of Sulfadoxine-Pyrimethamine Resistance Despite Reduction of Drug Pressure in Malawi

scientific article

Plasmodium falciparum field isolates from areas of repeated emergence of drug resistant malaria show no evidence of hypermutator phenotype

scientific article

Plasmodium falciparum malaria challenge by the bite of aseptic Anopheles stephensi mosquitoes: results of a randomized infectivity trial

scientific article (publication date: 21 October 2010)

Plasmodium vivax Infections over 3 Years in Duffy Blood Group Negative Malians in Bandiagara, Mali

scientific article

Platelet-mediated clumping of Plasmodium falciparum infected erythrocytes is associated with high parasitemia but not severe clinical manifestations of malaria in African children

scientific article

Pneumocystis pneumonia in HIV-positive adults, Malawi

scientific article published on February 2007

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine

scientific article

Polymorphisms in the K13-propeller gene in artemisinin-susceptible Plasmodium falciparum parasites from Bougoula-Hameau and Bandiagara, Mali

scientific article published on 27 April 2015

Preliminary study of quinine pharmacokinetics in pregnant women with malaria-HIV co-infection

scientific article published on 13 January 2014

Presidential Address: Tropical Medicine in War and Peace

scientific article published on 28 December 2015

Prevalence and distribution of human Plasmodium infection in Pakistan

scientific article published on 28 August 2013

Prevalence and patterns of antifolate and chloroquine drug resistance markers in Plasmodium vivax across Pakistan

scientific article published on 05 September 2013

Prevalence of Clinical and Subclinical Plasmodium falciparum and Plasmodium vivax Malaria in Two Remote Rural Communities on the Myanmar-China Border

scientific article published on 5 September 2017

Professor Ogobara K. Doumbo (1956-June 9, 2018)

scholarly article published by Christopher V Plowe in 2018

Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

scientific article (publication date: 9 May 2016)

Reduced T Regulatory Cell Response during Acute Plasmodium falciparum Infection in Malian Children Co-Infected with Schistosoma haematobium ⬇️

scientific article published on February 14, 2012

Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi

scientific article published on 21 May 2003

Relative contributions of various endogenous and exogenous factors to the mosquito microbiota

scientific article published on 10 December 2020

Return of chloroquine antimalarial efficacy in Malawi.

scientific article published on November 2006

Return of chloroquine-susceptible falciparum malaria in Malawi was a reexpansion of diverse susceptible parasites

scientific article

Safety and allele-specific immunogenicity of a malaria vaccine in Malian adults: results of a phase I randomized trial

scientific article published on 24 November 2006

Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults: results of a phase 1 randomized controlled trial

scientific article

Safety and immunogenicity of an AMA1 malaria vaccine in Malian children: results of a phase 1 randomized controlled trial

scientific article

Selection of antifolate-resistant Plasmodium falciparum by sulfadoxine-pyrimethamine treatment and infectivity to Anopheles mosquitoes.

scientific article published in September 2007

Serologic responses to the PfEMP1 DBL-CIDR head structure may be a better indicator of malaria exposure than those to the DBL-α tag

scientific article published on 13 August 2019

Seroreactivity to Plasmodium falciparum erythrocyte membrane protein 1 intracellular domain in malaria-exposed children and adults

scientific article published on 30 July 2013

Seroreactivity to a large panel of field-derived Plasmodium falciparum apical membrane antigen 1 and merozoite surface protein 1 variants reflects seasonal and lifetime acquired responses to malaria

scientific article

Serum antibody levels to glycosylphosphatidylinositols in specimens derived from matched Malian children with severe or uncomplicated Plasmodium falciparum malaria and healthy controls.

scientific article published on August 2006

Short report: rare Plasmodium falciparum merozoite surface protein 1 19-kda (msp-1(19)) haplotypes identified in Mali using high-throughput genotyping methods.

scientific article published on May 2007

Spatio-Temporal Dynamics of Asymptomatic Malaria: Bridging the Gap Between Annual Malaria Resurgences in a Sahelian Environment

scientific article published on 30 October 2017

Spatio-temporal analysis of malaria within a transmission season in Bandiagara, Mali

scientific article published on March 2013

Spread of artemisinin resistance in Plasmodium falciparum malaria

scientific article published on 31 July 2014

Stable malaria incidence despite scaling up control strategies in a malaria vaccine-testing site in Mali

scientific article

Strain-specific Plasmodium falciparum growth inhibition among Malian children immunized with a blood-stage malaria vaccine

scientific article

Strain-specific Plasmodium falciparum multifunctional CD4(+) T cell cytokine expression in Malian children immunized with the FMP2.1/AS02A vaccine candidate

scientific article published on 14 April 2016

Successful human infection with P. falciparum using three aseptic Anopheles stephensi mosquitoes: a new model for controlled human malaria infection

scientific article

Sulfadoxine-pyrimethamine-based combinations for malaria: a randomised blinded trial to compare efficacy, safety and selection of resistance in Malawi

scientific article

Sustained clinical efficacy of sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Malawi after 10 years as first line treatment: five year prospective study

scientific article published on 02 February 2004

TSCQ study: a randomized, controlled, open-label trial of daily trimethoprim-sulfamethoxazole or weekly chloroquine among adults on antiretroviral therapy in Malawi: study protocol for a randomized controlled trial

scientific article published on 18 July 2016

The (International) American Society of Tropical Medicine and Hygiene

scientific article published on November 2016

The Interaction between HIV and malaria in Africa

scientific article published in January 2007

The Jeremiah Metzger lecture: new additions to the toolbox for global malaria eradication

scientific article

The evolution of drug-resistant malaria

scientific article published on 12 December 2008

The potential role of vaccines in the elimination of falciparum malaria and the eventual eradication of malaria

scientific article published in December 2009

The rationale and plan for creating a World Antimalarial Resistance Network (WARN).

scientific article published on 6 September 2007

The threat of artemisinin-resistant malaria

scientific article published on September 2011

Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research.

scientific article

Two complement receptor one alleles have opposing associations with cerebral malaria and interact with α+thalassaemia.

scientific article published on 25 April 2018

Use of area under the curve to characterize transmission potential after antimalarial treatment.

scientific article published in October 2006

Using CF11 cellulose columns to inexpensively and effectively remove human DNA from Plasmodium falciparum-infected whole blood samples

scientific article published on 10 February 2012

Vaccine-Resistant Malaria

scientific article published on 21 October 2015

Variation in the circumsporozoite protein of Plasmodium falciparum: vaccine development implications

scientific article

Withdrawing antimalarial drugs: impact on parasite resistance and implications for malaria treatment policies

scientific article published in August 2004

World Antimalarial Resistance Network (WARN) III: molecular markers for drug resistant malaria

scientific article

World Antimalarial Resistance Network (WARN) IV: clinical pharmacology

scientific article

World Antimalarial Resistance Network I: clinical efficacy of antimalarial drugs

scientific article

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