List of works by Kevin Marsh

'Even if they ask you to stand by a tree all day, you will have to do it (laughter)...!': community voices on the notion and practice of informed consent for biomedical research in developing countries

scientific article published on 01 July 2005

10-year longitudinal study of malaria in children: Insights into acquisition and maintenance of naturally acquired immunity

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens

scientific article published on 23 December 2015

A community randomized controlled trial of insecticide-treated bednets for the prevention of malaria and anaemia among primigravid women on the Kenyan coast

scientific article published on March 1998

A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya

scientific article (publication date: 2014)

A high frequency African coding polymorphism in the N-terminal domain of ICAM-1 predisposing to cerebral malaria in Kenya.

scientific article published on August 1997

A highly conserved amino-acid sequence in thrombospondin, properdin and in proteins from sporozoites and blood stages of a human malaria parasite

scientific article published in September 1988

A library of functional recombinant cell-surface and secreted P. falciparum merozoite proteins

scientific article

A micro-epidemiological analysis of febrile malaria in Coastal Kenya showing hotspots within hotspots

scientific article published on 24 April 2014

A model for estimating total parasite load in falciparum malaria patients

scientific article published in July 2002

A molecular epidemiological study of var gene diversity to characterize the reservoir of Plasmodium falciparum in humans in Africa

scientific article

A non-sense mutation in Cd36 gene is associated with protection from severe malaria.

scientific article published in May 2001

A novel mis-sense mutation in the platelet glycoprotein CD36 is associated with protection from malaria

scholarly article by A. Pain et al published December 2000 in Transfusion Medicine

A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya

scientific article

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

scientific article

A polymorphism of intercellular adhesion molecule-1 is associated with a reduced incidence of nonmalarial febrile illness in Kenyan children

scientific article

A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria

scientific article published in June 1999

A promoter polymorphism in the gene encoding interleukin-12 p40 (IL12B) is associated with mortality from cerebral malaria and with reduced nitric oxide production

scientific article

A randomised, controlled trial of once daily and multi-dose daily gentamicin in young Kenyan infants

scientific article

A seven-year study on the effect of the pre-erythrocytic malaria vaccine candidate RTS,S/AS01 E on blood stage immunity in young Kenyan children.

scientific article

A single dose of intramuscular sulfadoxine-pyrimethamine as an adjunct to quinine in the treatment of severe malaria: pharmacokinetics and efficacy

scientific article published in March 1993

A single point in protein trafficking by Plasmodium falciparum determines the expression of major antigens on the surface of infected erythrocytes targeted by human antibodies

scientific article published on 19 May 2016

A threshold concentration of anti-merozoite antibodies is required for protection from clinical episodes of malaria

scientific article published on 22 June 2013

Abnormal respiratory patterns in childhood cerebral malaria

scientific article published in May 1998

Absence of crisis form factor in subjects immune to Plasmodium falciparum in The Gambia, West Africa

scientific article

Acidosis in severe childhood malaria

scientific article published in April 1997

Acquisition of growth-inhibitory antibodies against blood-stage Plasmodium falciparum

scientific article

Acquisition of naturally occurring antibody responses to recombinant protein domains of Plasmodium falciparum erythrocyte membrane protein 1.

scientific article published on 16 August 2008

Acridine orange fluorescence techniques as alternatives to traditional Giemsa staining for the diagnosis of malaria in developing countries

scientific article published in January 1996

Acute bacterial meningitis in children admitted to a rural Kenyan hospital: increasing antibiotic resistance and outcome

scientific article published on November 2002

Acute seizures attributable to falciparum malaria in an endemic area on the Kenyan coast ⬇️

scientific article

Admission diagnosis of cerebral malaria in adults in an endemic area of Tanzania: implications and clinical description

scientific article published on May 2003

Aetiology, outcome, and risk factors for mortality among adults with acute pneumonia in Kenya

scientific article

Africa in transition: the case of malaria

scientific article published in May 2016

Age, Spatial, and Temporal Variations in Hospital Admissions with Malaria in Kilifi County, Kenya: A 25-Year Longitudinal Observational Study

scientific article (publication date: June 2016)

Allele frequency-based and polymorphism-versus-divergence indices of balancing selection in a new filtered set of polymorphic genes in Plasmodium falciparum

scientific article

Allele-specific antibodies to Plasmodium falciparum merozoite surface protein-2 and protection against clinical malaria.

scientific article

Allelic diversity and naturally acquired allele-specific antibody responses to Plasmodium falciparum apical membrane antigen 1 in Kenya

scientific article

Alternating vector immunizations encoding pre-erythrocytic malaria antigens enhance memory responses in a malaria endemic area

scientific article published in August 2006

An analysis of the geographical distribution of severe malaria in children in Kilifi District, Kenya

scientific article published on April 1998

An approach to classifying sequence tags sampled from Plasmodium falciparum var genes

scientific article published on 25 March 2007

An assessment of the impact of host polymorphisms on Plasmodium falciparum var gene expression patterns among Kenyan children

scientific article

An immune basis for malaria protection by the sickle cell trait

scientific article

An increase in the burden of neonatal admissions to a rural district hospital in Kenya over 19 years

scientific article

An international qualitative study exploring patients' experiences of cutaneous leishmaniasis: study set-up and protocol.

scientific article published on 15 June 2018

An observational study of children with sickle cell disease in Kilifi, Kenya

scientific article published on 23 July 2009

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

scientific article published on 24 February 2021

An open randomized trial of artemether versus quinine in the treatment of cerebral malaria in African children

scientific article published in May 1996

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

scientific article (publication date: 19 July 2012)

Analysis of antibodies to newly described Plasmodium falciparum merozoite antigens supports MSPDBL2 as a predicted target of naturally acquired immunity

scientific article published on 29 July 2013

Analysis of immunity to febrile malaria in children that distinguishes immunity from lack of exposure

scientific article published on 17 February 2009

Anti-sporozoite antibodies and immunity to malaria in a rural Gambian population

scientific article published in January 1988

Antibodies to blood stage antigens of Plasmodium falciparum in rural Gambians and their relation to protection against infection

scientific article published in May 1989

Antibodies to polymorphic invasion-inhibitory and non-Inhibitory epitopes of Plasmodium falciparum apical membrane antigen 1 in human malaria ⬇️

scientific article

Antibodies to voltage-gated calcium channels in children with falciparum malaria

scientific article

Antibody mediated strain-specific agglutination of Plasmodium falciparum--parasitized erythrocytes visualized by ethidium bromide staining

scientific article published in November 1985

Antibody recognition of Plasmodium falciparum erythrocyte surface antigens in Kenya: evidence for rare and prevalent variants.

scientific article

Antigenic cartography of immune responses to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)

scientific article published on 01 July 2019

Antigens on the Plasmodium falciparum infected erythrocyte surface are parasite derived: a reply

scientific article published in October 1990

Assessment of severe malaria in a multicenter, phase III, RTS, S/AS01 malaria candidate vaccine trial: case definition, standardization of data collection and patient care

scientific article

Association of the GNAS locus with severe malaria

scientific article published on 26 October 2008

Asymptomatic malaria parasitaemia and seizure control in children with nodding syndrome; a cross-sectional study

scholarly article by Rodney Ogwang et al published 18 October 2018 in BMJ Open

Autoagglutination of malaria-infected red blood cells and malaria severity

scientific article published in April 2000

Averting a malaria disaster

scientific article published on June 1999

Avidity of anti-circumsporozoite antibodies following vaccination with RTS,S/AS01E in young children

scientific article

B cell memory to 3 Plasmodium falciparum blood-stage antigens in a malaria-endemic area

scientific article published on 13 April 2005

Bacteraemia complicating severe malaria in children

scientific article published in May 1999

Bacteraemia in Kenyan children with sickle-cell anaemia: a retrospective cohort and case-control study

scientific article published on 09 September 2009

Bacteremia among children admitted to a rural hospital in Kenya

scientific article published in January 2005

Bayesian age-stage modelling of Plasmodium falciparum sequestered parasite loads in severe malaria patients

scientific article published on September 2004

Bed-nets (mosquito-nets) and morbidity from malaria

scientific article published in July 1986

Binding of Plasmodium falciparum-infected erythrocytes to soluble platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): frequent recognition by clinical isolates.

scientific article

Blood group O protects against severe Plasmodium falciparum malaria through the mechanism of reduced rosetting

scholarly article

Brain swelling and ischaemia in Kenyans with cerebral malaria

scientific article

Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malaria

scientific article published on 3 March 2008

Breadth of anti-merozoite antibody responses is associated with the genetic diversity of asymptomatic Plasmodium falciparum infections and protection against clinical malaria

scientific article published on 27 August 2013

Burden, features, and outcome of neurological involvement in acute falciparum malaria in Kenyan children

scientific article published on May 2007

CD4 T cell responses to a variant antigen of the malaria parasite Plasmodium falciparum, erythrocyte membrane protein-1, in individuals living in malaria-endemic areas

scientific article published on 28 February 2002

CD4 T cells from malaria-nonexposed individuals respond to the CD36-Binding Domain of Plasmodium falciparum erythrocyte membrane protein-1 via an MHC class II-TCR-independent pathway

scientific article

CD4+ T cell responses to the Plasmodium falciparum erythrocyte membrane protein 1 in children with mild malaria

scientific article published on 22 January 2014

CISH and susceptibility to infectious diseases

scientific article

Case definitions of clinical malaria under different transmission conditions in Kilifi District, Kenya

scientific article published on 26 April 2005

Case-control studies of severe malaria

scientific article published on June 1992

Cellular reactivity to the p. Falciparum protein trap in adult kenyans: novel epitopes, complex cytokine patterns, and the impact of natural antigenic variation.

scientific article published on March 2006

Cerebral malaria

scientific article published in The Lancet

Cerebral malaria versus bacterial meningitis in children with impaired consciousness.

scientific article

Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcome

scientific article published in October 2010

Cerebrospinal fluid studies in children with cerebral malaria: an excitotoxic mechanism?

scientific article published in February 2000

Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection

scientific article published on 13 October 2016

Changing home treatment of childhood fevers by training shop keepers in rural Kenya

scientific article published on May 1999

Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia

scientific article published on 09 January 2017

Characterization and localization of Plasmodium falciparum surface antigens on infected erythrocytes from west African patients

scientific article published in July 1991

Characterization of a Plasmodium falciparum macrophage-migration inhibitory factor homologue

scientific article (publication date: 15 March 2007)

Characterization of the repertoire diversity of the Plasmodium falciparum stevor multigene family in laboratory and field isolates

scientific article published on 26 June 2009

Chemosensitization of Plasmodium falciparum by probenecid in vitro

scientific article

Childhood deaths in Africa: uses and limitations of verbal autopsies

scientific article published on August 1992

Chloroquine is not a risk factor for seizures in childhood cerebral malaria

scientific article published on December 2000

Chloroquine resistance before and after its withdrawal in Kenya

scientific article published on 18 May 2009

Chlorproguanil-dapsone versus sulfadoxine-pyrimethamine for sequential episodes of uncomplicated falciparum malaria in Kenya and Malawi: a randomised clinical trial

scientific article published in October 2002

Chlorproguanil-dapsone: effective treatment for uncomplicated falciparum malaria.

scientific article

Chlorproguanil/dapsone for uncomplicated Plasmodium falciparum malaria in young children: pharmacokinetics and therapeutic range ⬇️

scientific article published on May 1, 1997

Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion

scientific article published on 21 December 2012

Chronic salicylate poisoning and severe malaria

scientific article published on June 1996

Circumsporozoite-specific T cell responses in children vaccinated with RTS,S/AS01E and protection against P falciparum clinical malaria

scientific article (publication date: 2011)

Clearance of asymptomatic P. falciparum Infections Interacts with the number of clones to predict the risk of subsequent malaria in Kenyan children

scientific article

Clearing asymptomatic parasitaemia increases the specificity of the definition of mild febrile malaria

scientific article published on 15 August 2007

Clinical algorithm for malaria in Africa

scientific article published on 01 May 1996

Clinical algorithms for malaria diagnosis lack utility among people of different age groups

scientific article

Clinical features and pathogenesis of severe malaria

scientific article

Clinical overlap between malaria and severe pneumonia in Africa children in hospital

scientific article

Clinical research in resource-limited settings: enhancing research capacity and working together to make trials less complicated

scientific article

Cognitive sequelae of severe malaria with impaired consciousness

scientific article published in September 1999

Coma scales for children with severe falciparum malaria

scientific article published in March 1997

Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria

scientific article

Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy

scientific article

Comparative folate metabolism in humans and malaria parasites (part II): activities as yet untargeted or specific to Plasmodium

scientific article

Comparative transcriptional and genomic analysis of Plasmodium falciparum field isolates

scientific article published on 30 October 2009

Congenital and neonatal malaria in a rural Kenyan district hospital: an eight-year analysis

scientific article

Contrasting signatures of selection on the Plasmodium falciparum erythrocyte binding antigen gene family

scientific article published on 22 June 2006

Cord blood IgG and the risk of severe Plasmodium falciparum malaria in the first year of life

scientific article

Correction: Safety of the Malaria Vaccine Candidate, RTS,S/AS01E in 5 to 17 Month Old Kenyan and Tanzanian Children.

scientific article

Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4 CD25 high T cells with susceptibility in Kenyans

scientific article published on 30 April 2008

Cytokine mRNA expression and iron status in children living in a malaria endemic area

scientific article published in April 2005

Declining malaria transmission differentially impacts on the maintenance of humoral immunity to Plasmodium falciparum in children

scientific article published on 2 August 2017

Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast

scientific article

Deep breathing in children with severe malaria: indicator of metabolic acidosis and poor outcome

scientific article

Defining childhood severe falciparum malaria for intervention studies

scientific article

Defining clinical malaria: the specificity and incidence of endpoints from active and passive surveillance of children in rural Kenya

scientific article

Development and optimization of high-throughput methods to measure Plasmodium falciparum-specific growth inhibitory antibodies

scientific article

Development of a malaria vaccine

scientific article published on December 1997

Diagnosis of acute bacterial meningitis in children at a district hospital in sub-Saharan Africa.

scientific article published in June 2001

Diagnosis of pneumococcal pneumonia by psaA PCR analysis of lung aspirates from adult patients in Kenya

scientific article

Differing rates of antibody acquisition to merozoite antigens in malaria: implications for immunity and surveillance

scientific article published on 11 November 2016

Dynamics and role of antibodies to Plasmodium falciparum merozoite antigens in children living in two settings with differing malaria transmission intensity

scientific article

Early gamma interferon and interleukin-2 responses to vaccination predict the late resting memory in malaria-naïve and malaria-exposed individuals

scientific article

Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, Kenya

scientific article

Effect of phenobarbital on seizure frequency and mortality in childhood cerebral malaria: a randomised, controlled intervention study

scientific article published on February 2000

Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children ⬇️

scientific article

Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5-17 months in Kenya and Tanzania: a randomised controlled trial

scientific article published on 13 January 2011

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

scientific article

Electroencephalographic and clinical features of cerebral malaria

scientific article

Elevated plasma urokinase receptor predicts low birth weight in maternal malaria

scientific article published on January 2007

Environmental and entomological risk factors for the development of clinical malaria among children on the Kenyan coast

scientific article published on July 1998

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype

scientific article published on 9 November 2009

Epileptic seizures and malaria in Kenyan children

scientific article published on March 1996

Erythrocyte-binding antigens of Plasmodium falciparum are targets of human inhibitory antibodies and function to evade naturally acquired immunity

scientific article published on 17 June 2013

Estimating individual exposure to malaria using local prevalence of malaria infection in the field

scientific article

Estimating mortality, morbidity and disability due to malaria among Africa's non-pregnant population.

scientific article

Estimation of the sequestered parasite load in severe malaria patients using both host and parasite markers.

scientific article

Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection

scientific article

Evidence for over-dispersion in the distribution of clinical malaria episodes in children

scientific article

Evidence for the involvement of VAR2CSA in pregnancy-associated malaria

scientific article

Ex vivo interferon-gamma immune response to thrombospondin-related adhesive protein in coastal Kenyans: longevity and risk of Plasmodium falciparum infection.

scientific article published in April 2003

Examining the human infectious reservoir for Plasmodium falciparum malaria in areas of differing transmission intensity

scientific article published on 26 October 2017

Excess child mortality after discharge from hospital in Kilifi, Kenya: a retrospective cohort analysis

scientific article published on 13 July 2011

Expression of Plasmodium falciparum genes involved in erythrocyte invasion varies among isolates cultured directly from patients ⬇️

scientific article

Extended follow-up following a phase 2b randomized trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya

scientific article

Factors influencing admission to hospital during terminal childhood illnesses in Kenya

scientific article published on October 1994

Failure to respond to the surface of Plasmodium falciparum infected erythrocytes predicts susceptibility to clinical malaria amongst African children

scientific article published on 29 April 2008

Falciparum malaria: differential effects of antimalarial drugs on ex vivo parasite viability during the critical early phase of therapy.

scientific article published in July 1993

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children

scientific article

Four-year efficacy of RTS,S/AS01E and its interaction with malaria exposure

scientific article published on March 2013

Fresh isolates from children with severe Plasmodium falciparum malaria bind to multiple receptors.

scientific article published on September 2001

Gametocyte carriage in an era of changing malaria epidemiology: A 19-year analysis of a malaria longitudinal cohort

scholarly article by Michelle K. Muthui et al published 5 April 2019 in Wellcome Open Research

Gametocyte carriage in an era of changing malaria epidemiology: A 19-year analysis of a malaria longitudinal cohort

scientific article published on 28 May 2019

Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine

scientific article published on 21 October 2015

Genetic determinants of anti-malarial acquired immunity in a large multi-centre study

scientific article

Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure

scientific article

Genome-wide and fine-resolution association analysis of malaria in West Africa

scientific article

Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya

scientific article

Genomewide analysis of the host response to malaria in Kenyan children

scientific article published on 14 April 2005

Genomic epidemiology of the current wave of artemisinin resistant malaria

scholarly article by Roberto Amato et al published 22 May 2015 in bioRxiv

Genomic representation of var gene sequences in Plasmodium falciparum field isolates from different geographic regions

scientific article published in August 1997

Glucose Homeostasis in Children with Falciparum Malaria: Precursor Supply Limits Gluconeogenesis and Glucose Production1 ⬇️

scientific article published on August 1, 1997

HIV infection, malnutrition, and invasive bacterial infection among children with severe malaria

scientific article

Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria

scientific article

Halofantrine pharmacokinetics in Kenyan children with non-severe and severe malaria

scientific article

Helminth infection and eosinophilia and the risk of Plasmodium falciparum malaria in 1- to 6-year-old children in a malaria endemic area

scientific article

Heritability of malaria in Africa

scientific article

High Sporozoite Antibody Titers in Conjunction with Microscopically Detectable Blood Infection Display Signatures of Protection from Clinical Malaria

scientific article

High efficiency human memory B cell assay and its application to studying Plasmodium falciparum-specific memory B cells in natural infections

scientific article published on 22 September 2011

High levels of serum antibodies to merozoite surface protein 2 of Plasmodium falciparum are associated with reduced risk of clinical malaria in coastal Kenya

scientific article

High mortality from Plasmodium falciparum malaria in children living with sickle cell anemia on the coast of Kenya

scientific article

Homozygosity and risk of childhood death due to invasive bacterial disease

scientific article

Host-parasite interaction and morbidity in malaria endemic areas

scientific article

Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria ⬇️

scientific article

Human antibodies to recombinant protein constructs of Plasmodium falciparum Apical Membrane Antigen 1 (AMA1) and their associations with protection from malaria

scientific article

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study

article

Hypoglycaemia in African children with severe malaria

scientific article published on March 1987

Hypoglycaemia on and after admission in Kenyan children with severe malaria.

scientific article published in March 1998

Hyponatraemia and dehydration in severe malaria.

scientific article

Hypothetical performance of syndrome-based management of acute paediatric admissions of children aged more than 60 days in a Kenyan district hospital

scientific article published on 16 May 2003

Identification of frequently recognized dimorphic T-cell epitopes in plasmodium falciparum merozoite surface protein-1 in West and East Africans: lack of correlation of immune recognition and allelic prevalence

scientific article published in March 2001

Identifying children with excess malaria episodes after adjusting for variation in exposure: identification from a longitudinal study using statistical count models

scientific article published on 6 August 2015

IgG antibody responses to Plasmodium falciparum merozoite antigens in Kenyan children have a short half-life

scientific article published on 28 June 2007

IgM in human immunity to Plasmodium falciparum malaria

scientific article published on 25 September 2019

Immunity to malaria: more questions than answers

scientific article published on July 2008

Immunity to non-cerebral severe malaria is acquired after one or two infections

scientific article (publication date: March 1999)

Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

scientific article

Immunogenicity of the candidate malaria vaccines FP9 and modified vaccinia virus Ankara encoding the pre-erythrocytic antigen ME-TRAP in 1-6 year old children in a malaria endemic area

scientific article published on 31 March 2006

Impact of 10-valent pneumococcal conjugate vaccine on invasive pneumococcal disease and nasopharyngeal carriage in Kenya

scholarly article published 18 July 2018

Impact of UK malaria prophylaxis policy on imported malaria

scientific article

Impaired uteroplacental blood flow in pregnancies complicated by falciparum malaria

scientific article published in February 2002

Improving malaria home treatment by training drug retailers in rural Kenya.

scientific article published on April 2004

Imputation-based meta-analysis of severe malaria in three African populations

scientific article

In vitro activities of 2,4-diaminoquinazoline and 2,4-diaminopteridine derivatives against Plasmodium falciparum

scientific article published on October 2004

In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.

scientific article published on 21 September 2009

Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies

scientific article

Indicators of life-threatening malaria in African children

scientific article

Individual-level variations in malaria susceptibility and acquisition of clinical protection

Induction of T helper type 1 and 2 responses to 19-kilodalton merozoite surface protein 1 in vaccinated healthy volunteers and adults naturally exposed to malaria

scientific article

Infant parasite rates and immunoglobulin M seroprevalence as a measure of exposure to Plasmodium falciparum during a randomized controlled trial of insecticide-treated bed nets on the Kenyan coast.

scientific article published on August 1996

Inflammatory mediators in children with protein-energy malnutrition

scientific article published on 01 May 1997

Inhibition of Plasmodium falciparum growth by IgG antibody produced by human lymphocytes transformed with Epstein-Barr virus

scientific article

Insecticide-treated bednets reduce mortality and severe morbidity from malaria among children on the Kenyan coast.

scientific article published on April 1996

Inter-observer agreement of the assessment of coma scales and brainstem signs in non-traumatic coma.

scientific article published in September 1995

Interactions between age and ITN use determine the risk of febrile malaria in children

scientific article

Intercellular adhesion molecule-1 is an endothelial cell adhesion receptor for Plasmodium falciparum

scientific article published in September 1989

Intermittent preventive sulfadoxine-pyrimethamine treatment of primigravidae reduces levels of plasma immunoglobulin G, which protects against pregnancy-associated Plasmodium falciparum malaria

scientific article published on September 2004

Intermittent sulphadoxine-pyrimethamine to prevent severe anaemia secondary to malaria in pregnancy: a randomised placebo-controlled trial

scientific article published on February 1999

Interobserver variation in respiratory signs of severe malaria

scientific article published on April 1995

Intracranial hypertension in Africans with cerebral malaria

scientific article

Intracranial pressure in African children with cerebral malaria

scientific article published in March 1991

Invasion pathways and malaria severity in Kenyan Plasmodium falciparum clinical isolates ⬇️

scientific article published on 16 April 2007

Invasive Gram-negative bacilli are frequently resistant to standard antibiotics for children admitted to hospital in Kilifi, Kenya

scientific article published on 19 May 2005

Iron deficiency and malaria among children living on the coast of Kenya

scientific article published on 2 July 2004

Kinetics of antibody responses to Plasmodium falciparum-infected erythrocyte variant surface antigens

scientific article published on 7 February 2003

Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations

scientific article

Lack of avidity maturation of merozoite antigen-specific antibodies with increasing exposure to Plasmodium falciparum amongst children and adults exposed to endemic malaria in Kenya

scientific article

Lactic acidosis and oxygen debt in African children with severe anaemia

scientific article published on September 1997

Lessons learnt from the first controlled human malaria infection study conducted in Nairobi, Kenya

scientific article published on 28 April 2015

Limited Spatial Clustering of Individual Plasmodium falciparum Alleles in Field Isolates from Coastal Kenya ⬇️

scientific article published on August 1, 1997

Limited antigenic diversity of Plasmodium falciparum apical membrane antigen 1 supports the development of effective multi-allele vaccines

scientific article

Longitudinal analyses of immune responses to Plasmodium falciparum derived peptides corresponding to novel blood stage antigens in coastal Kenya

scientific article published on 26 February 2008

Low multiplication rates of African Plasmodium falciparum isolates and lack of association of multiplication rate and red blood cell selectivity with malaria virulence

scientific article published on April 2006

Low-level Plasmodium falciparum transmission and the incidence of severe malaria infections on the Kenyan coast.

scientific article published on August 1993

Malaria and Age Variably but Critically Control Hepcidin Throughout Childhood in Kenya

scientific article

Malaria and nutritional status in children living on the coast of Kenya

scientific article published in December 2004

Malaria as a cause of morbidity and mortality in children with homozygous sickle cell disease on the coast of Kenya

scientific article published on July 2009

Malaria eradication and elimination: views on how to translate a vision into reality

scientific article published on 25 July 2015

Malaria hotspots defined by clinical malaria, asymptomatic carriage, PCR and vector numbers in a low transmission area on the Kenyan Coast

scientific article published on 14 April 2016

Malaria in Africa: progress and prospects in the decade since the Abuja Declaration

scientific article

Malaria in patients with sickle cell anemia: burden, risk factors, and outcome at the outpatient clinic and during hospitalization

scientific article

Malaria in pregnancy: adverse effects on haemoglobin levels and birthweight in primigravidae and multigravidae

scientific article published on October 2001

Malaria is an important cause of anaemia in primigravidae: evidence from a district hospital in coastal Kenya

scientific article published on September 1996

Malaria transmission and morbidity.

scientific article

Malaria: Biology and Disease

scientific article published on October 2016

Management of severe malaria: implications for research

scientific article

Maternal HIV infection and placental malaria reduce transplacental antibody transfer and tetanus antibody levels in newborns in Kenya

scientific article

Maternal recall of symptoms associated with childhood deaths in rural east Africa

scientific article published on August 1993

Memory B cells are a more reliable archive for historical antimalarial responses than plasma antibodies in no-longer exposed children

scientific article

Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa

scientific article

Mortality among Kenyan children admitted to a rural district hospital on weekends as compared with weekdays

scientific article published in December 2004

Mortality and morbidity from malaria among children in a rural area of The Gambia, West Africa

scientific article

Mortality in sickle cell anemia in Africa: a prospective cohort study in Tanzania

scientific article

Multiple clinical episodes of Plasmodium falciparum malaria in a low transmission intensity setting: exposure versus immunity

scientific article published on 13 May 2015

Naturally acquired antibodies to polymorphic and conserved epitopes of Plasmodium falciparum merozoite surface protein 3.

scientific article

Naturally acquired immune responses against Plasmodium falciparum sporozoites and liver infection

scientific article published on 26 April 2012

Naturally acquired immunity to Plasmodium falciparum

Naturally acquired immunoglobulin (Ig)G subclass antibodies to crude asexual Plasmodium falciparum lysates: evidence for association with protection for IgG1 and disease for IgG2.

scientific article published in February 2002

Negative epistasis between the malaria-protective effects of alpha+-thalassemia and the sickle cell trait

scientific article

Neonatal measles immunity in rural Kenya: the influence of HIV and placental malaria infections on placental transfer of antibodies and levels of antibody in maternal and cord serum samples

scientific article

New antigens for a multicomponent blood-stage malaria vaccine

scientific article published in July 2014

New insights into the epidemiology of malaria relevant for disease control

scientific article published on January 1998

Nonimmune IgM, but not IgG binds to the surface of Plasmodium falciparum-infected erythrocytes and correlates with rosetting and severe malaria

scientific article published in June 2002

Nutritional status, hospitalization and mortality among patients with sickle cell anemia in Tanzania

scientific article

Opsonic phagocytosis of Plasmodium falciparum merozoites: mechanism in human immunity and a correlate of protection against malaria

scientific article

Oxidative stress and erythrocyte damage in Kenyan children with severe Plasmodium falciparum malaria.

scientific article published in May 2001

Paediatric survival and re-admission risks following hospitalization on the Kenyan coast

scientific article published on May 2000

Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria.

scientific article published on March 1998

Parasite viability during treatment of severe falciparum malaria: differential effects of artemether and quinine.

scientific article published in September 1995

Parasitized erythrocyte antigens and thrombospondin adhesion in the immunology and pathogenesis of falciparum malaria

scientific article published on 01 January 1986

Pathophysiology of severe malaria in children

scientific article published on April 2004

Perceptions of symptoms of severe childhood malaria among Mijikenda and Luo residents of coastal Kenya.

scientific article published on April 1995

Peripheral blood dendritic cells in children with acute Plasmodium falciparum malaria.

scientific article published on November 2001

Peripheral blood monocyte-to-lymphocyte ratio at study enrollment predicts efficacy of the RTS,S malaria vaccine: analysis of pooled phase II clinical trial data

scientific article

Perturbations of cerebral hemodynamics in Kenyans with cerebral malaria

scientific article published in July 1996

PfEMP1, polymorphism and pathogenesis

scientific article published on July 1997

Pharmacokinetics and anticonvulsant effects of diazepam in children with severe falciparum malaria and convulsions.

scientific article published on January 2002

Pharmacology of absorption and distribution: optimal use of antimalarial drugs in the treatment of severe falciparum malaria in Kenya.

scientific article published in February 1994

Phenotypic and functional profiling of CD4 T cell compartment in distinct populations of healthy adults with different antigenic exposure

scientific article

Photographic and Angiographic Characterization of the Retina of Kenyan Children With Severe Malaria ⬇️

scientific article published on August 1, 1997

Plasmodium falciparum STEVOR proteins are highly expressed in patient isolates and located in the surface membranes of infected red blood cells and the apical tips of merozoites

scientific article published on 12 May 2008

Plasmodium falciparum antigenic variation. Mapping mosaic var gene sequences onto a network of shared, highly polymorphic sequence blocks

scientific article published on 21 April 2008

Plasmodium falciparum antigenic variation: relationships between in vivo selection, acquired antibody response, and disease severity

scientific article published on 12 August 2005

Plasmodium falciparum antigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria

scientific article

Plasmodium falciparum cytoadherence to ICAM-1 is associated with cerebral malaria.

scientific article

Plasmodium falciparum infection patterns since birth and risk of severe malaria: a nested case-control study in children on the coast of Kenya

scientific article

Plasmodium falciparum infections are associated with agglutinating antibodies to parasite-infected erythrocyte surface antigens among healthy Kenyan children

scientific article published on 17 May 2002

Plasmodium falciparum intercellular adhesion molecule-1-based cytoadherence-related signaling in human endothelial cells

scientific article published on 5 June 2007

Plasmodium falciparum malaria in children aged 0-2 years: the role of foetal haemoglobin and maternal antibodies to two asexual malaria vaccine candidates (MSP3 and GLURP).

scientific article

Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure

scientific article published on 23 August 2017

Plasmodium falciparum var gene expression homogeneity as a marker of the host-parasite relationship under different levels of naturally acquired immunity to malaria

scientific article

Plasmodium falciparum var gene expression is modified by host immunity

scientific article published on 11 December 2009

Plasmodium falciparum variant surface antigen expression patterns during malaria

scientific article

Plasmodium falciparum-infected erythrocytes: agglutination by diverse Kenyan plasma is associated with severe disease and young host age.

scientific article

Plasmodium falciparum: A Method for the Amplification of S Antigens and Its Application to Laboratory and Field Samples

scientific article published on 01 December 1993

Plasmodium falciparum: a family of sulphated glycoconjugates disrupts erythrocyte rosettes

scientific article published in December 1994

Plasmodium falciparum: the behavior of clinical isolates in an in vitro model of infected red blood cell sequestration

scientific article

Plasmodium falciparum: the human agglutinating antibody response to the infected red cell surface is predominantly variant specific

scientific article

Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria

scientific article

Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay

scientific article

Population pharmacokinetics of artemether and dihydroartemisinin following single intramuscular dosing of artemether in African children with severe falciparum malaria

scientific article published in February 2004

Positive replication and linkage disequilibrium mapping of the chromosome 21q22.1 malaria susceptibility locus

scientific article

Positive selection of a CD36 nonsense variant in sub-saharan Africa, but no association with severe malaria phenotypes

scientific article published on 29 April 2009

Pre-transfusion management of children with severe malarial anaemia: a randomised controlled trial of intravascular volume expansion

scientific article published in February 2005

Prevalence of serum neutralizing antibodies against chimpanzee adenovirus 63 and human adenovirus 5 in Kenyan children, in the context of vaccine vector efficacy

scientific article published on 16 April 2009

Prevalence, causes, and behavioral and emotional comorbidities of acute symptomatic seizures in Africa: A critical review.

scientific article

Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults

scientific article

Profile: The Kilifi Health and Demographic Surveillance System (KHDSS)

scientific article (publication date: June 2012)

Prognostic indicators of early and late death in children admitted to district hospital in Kenya: cohort study

scientific article

Prognostic indicators of life-threatening malaria are associated with distinct parasite variant antigen profiles

scientific article published on April 2012

Prognostic value of CSF lactate in cerebral malaria

scientific article published in May 1987

Progressive increase in antimicrobial resistance among invasive isolates of Haemophilus influenzae obtained from children admitted to a hospital in Kilifi, Kenya, from 1994 to 2002 ⬇️

scientific article

Promoting the social value of research in Kenya: examining the practical aspects of collaborative partnerships using an ethical framework

scientific article published on 09 April 2008

Prophylactic phenobarbitone in young children with severe falciparum malaria: pharmacokinetics and clinical effects

scientific article published on February 1992

Prospective identification of malaria parasite genes under balancing selection

scientific article published on 15 May 2009

Protection against clinical malaria by heterologous immunoglobulin G antibodies against malaria-infected erythrocyte variant surface antigens requires interaction with asymptomatic infections

scientific article published on 22 September 2004

Protection by alpha-thalassaemia against Plasmodium falciparum malaria: modified surface antigen expression rather than impaired growth or cytoadherence

scientific article published in October 1991

Quinine sensitivity of isolates of Plasmodium falciparum from the coast of Kenya

scientific article published in March 1998

Quinine treatment of severe falciparum malaria in African children: a randomized comparison of three regimens

scientific article published on December 1991

Randomized trial of volume expansion with albumin or saline in children with severe malaria: preliminary evidence of albumin benefit

scientific article published on 25 January 2005

Rapid switching to multiple antigenic and adhesive phenotypes in malaria

scientific article published on June 1992

Receptor-specific adhesion and clinical disease in Plasmodium falciparum

scientific article published on October 1997

Regulation of immune response by Plasmodium-infected red blood cells.

scientific article

Relation between falciparum malaria and bacteraemia in Kenyan children: a population-based, case-control study and a longitudinal study

scientific article

Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa

scientific article published on June 1997

Relationships between Plasmodium falciparum transmission by vector populations and the incidence of severe disease at nine sites on the Kenyan coast

scientific article published on March 1995

Report of a consultation on the optimization of clinical challenge trials for evaluation of candidate blood stage malaria vaccines, 18-19 March 2009, Bethesda, MD, USA.

scientific article published on 3 August 2009

Research priorities for malaria elimination

scientific article published on 28 October 2010

Resistance to malaria through structural variation of red blood cell invasion receptors

scientific article published on 18 May 2017

Resistance to malaria through structural variation of red blood cell invasion receptors

scholarly article published 26 October 2016

Retinal haemorrhages in falciparum malaria

scientific article published on June 1991

Rheological analysis of the adhesive interactions of red blood cells parasitized by Plasmodium falciparum.

scientific article published in February 1992

Risk factors for high cerebral blood flow velocity and death in Kenyan children with Sickle Cell Anaemia: role of haemoglobin oxygen saturation and febrile illness

scientific article

Risk of severe malaria among African infants: direct evidence of clinical protection during early infancy

scientific article published on March 1998

Safety of the malaria vaccine candidate, RTS,S/AS01E in 5 to 17 month old Kenyan and Tanzanian Children

scientific article (publication date: 29 November 2010)

Safety profile of the viral vectors of attenuated fowlpox strain FP9 and modified vaccinia virus Ankara recombinant for either of 2 preerythrocytic malaria antigens, ME-TRAP or the circumsporozoite protein, in children and adults in Kenya

scientific article published on 14 March 2006

Screening for severe anaemia in pregnancy in Kenya, using pallor examination and self-reported morbidity

scientific article published on May 2001

Seizures and status epilepticus in childhood cerebral malaria

scientific article published in August 1996

Serological Conservation of Parasite-Infected Erythrocytes Predicts Plasmodium falciparum Erythrocyte Membrane Protein 1 Gene Expression but Not Severity of Childhood Malaria

scientific article published on 16 February 2016

Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites

scientific article (publication date: 2011)

Serotype distribution and prevalence of resistance to benzylpenicillin in three representative populations of Streptococcus pneumoniae isolates from the coast of Kenya.

scientific article published in December 1998

Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children

scientific article published on June 2016

Severe P. falciparum malaria in Kenyan children: evidence for hypovolaemia

scientific article

Severe anaemia in children living in a malaria endemic area of Kenya

scientific article published on February 1997

Severe childhood malaria in two areas of markedly different falciparum transmission in east Africa

scientific article published on September 1994

Sickle cell disease in Africa: burden and research priorities

scientific article published on January 2007

Sickle cell trait and the risk of Plasmodium falciparum malaria and other childhood diseases

scientific article

Signs of dehydration in severe childhood malaria

scientific article published in October 1997

Specific receptor usage in Plasmodium falciparum cytoadherence is associated with disease outcome

scientific article

Stable and unstable malaria hotspots in longitudinal cohort studies in Kenya

scientific article

Surface antigen expression on Plasmodium falciparum-infected erythrocytes is modified in alpha- and beta-thalassemia

scientific article published on April 1991

T-cell control of Epstein–Barr virus-infected B cells is lost during P. falciparum malaria ⬇️

scientific article published on December 29, 1984

T-cell responses to the DBLα-tag, a short semi-conserved region of the Plasmodium falciparum membrane erythrocyte protein 1.

scientific article

Targets and Mechanisms Associated with Protection from Severe Plasmodium falciparum Malaria in Kenyan Children

scientific article published on 19 January 2016

Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunity

scientific article

Temporal association of acute hepatitis A and Plasmodium falciparum malaria in children

scientific article

Temporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal Kenya

scientific article (publication date: December 2014)

The accuracy of the clinical histories given by mothers of seriously ill African children

scientific article

The binding site on ICAM-1 for Plasmodium falciparum-infected erythrocytes overlaps, but is distinct from, the LFA-1-binding site

scientific article

The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

scientific article

The changing limits and incidence of malaria in Africa: 1939-2009.

scientific article

The consequences of reducing transmission of Plasmodium falciparum in Africa

scientific article

The decline in paediatric malaria admissions on the coast of Kenya

scientific article

The disposition of intramuscular artemether in children with cerebral malaria; a preliminary study

scientific article published in May 1997

The disposition of oral and intramuscular pyrimethamine/sulphadoxine in Kenyan children with high parasitaemia but clinically non-severe falciparum malaria ⬇️

scientific article published on February 1, 1992

The effect of alpha+-thalassaemia on the incidence of malaria and other diseases in children living on the coast of Kenya

scientific article

The effect of declining exposure on T cell-mediated immunity to Plasmodium falciparum - an epidemiological "natural experiment".

scientific article

The effects of Plasmodium falciparum malaria on immune control of B lymphocytes in Gambian children

scientific article published in May 1990

The effects of malaria control on nutritional status in infancy

scientific article published on April 1997

The effects of untreated bednets on malaria infection and morbidity on the Kenyan coast

scientific article published on July 2003

The epidemiology of clinical malaria among African children

scientific article published on March 1998

The epidemiology of hookworm infection and its contribution to anaemia among pre-school children on the Kenyan coast

scientific article published on May 1999

The frequency of BDCA3-positive dendritic cells is increased in the peripheral circulation of Kenyan children with severe malaria

scientific article

The haptoglobin 2-2 genotype is associated with a reduced incidence of Plasmodium falciparum malaria in children on the coast of Kenya

scientific article published on 07 February 2007

The impact of 10-valent Pneumococcal Conjugate Vaccine on the incidence of radiologically-confirmed pneumonia and clinically-defined pneumonia in Kenyan children

scholarly article published 18 July 2018

The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum

scientific article published on September 2007

The influence of alanine infusion on glucose production in 'malnourished' African children with falciparum malaria

scientific article published in July 1997

The past, present and future of childhood malaria mortality in Africa

scientific article

The pathogenesis of severe malaria in African children

scientific article

The pathogenic basis of malaria

scientific article (publication date: 7 February 2002)

The plasma concentration of the B cell activating factor is increased in children with acute malaria

scientific article

The prevalence and morbidity of snake bite and treatment-seeking behaviour among a rural Kenyan population.

scientific article published on December 1994

The ratio of monocytes to lymphocytes in peripheral blood correlates with increased susceptibility to clinical malaria in Kenyan children

scientific article

The relationship between glucose production and plasma glucose concentration in children with falciparum malaria

scientific article published in November 1996

The role of antibodies to Plasmodium falciparum-infected-erythrocyte surface antigens in naturally acquired immunity to malaria

scientific article

The role of reduced red cell deformability in the pathogenesis of severe falciparum malaria and its restoration by blood transfusion

scientific article

The role of sequential administration of sulphadoxine/pyrimethamine following quinine in the treatment of severe falciparum malaria in children

scientific article published on May 2005

The role of shops in the treatment and prevention of childhood malaria on the coast of Kenya

scientific article published on May 1992

The use of cryopreserved mature trophozoites in assessing antibody recognition of variant surface antigens of Plasmodium falciparum-infected erythrocytes

scientific article published in May 2004

Therapeutic potential of folate uptake inhibition in Plasmodium falciparum

scientific article

Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: unbound quinine concentrations following a simple loading dose regimen

scientific article published in September 1994

Transfusion for respiratory distress in life-threatening childhood malaria.

scientific article

Transient cross-reactive immune responses can orchestrate antigenic variation in malaria

scientific article

Transmission-dependent tolerance to multiclonal Plasmodium falciparum infection

scientific article published on October 2009

Trust and informed consent: insights from community members on the Kenyan coast.

scientific article published on 12 February 2005

Tumor necrosis factor and lymphotoxin-alpha polymorphisms and severe malaria in African populations

scientific article published on February 2009

Ultrastructure of the erythrocytic stages of Plasmodium malariae

scientific article published in August 1987

Understanding of informed consent in a low-income setting: three case studies from the Kenyan Coast

scientific article

Use of clinical syndromes to target antibiotic prescribing in seriously ill children in malaria endemic area: observational study

scientific article

Validation of immunoglobulin G enzyme-linked immunosorbent assay for antibodies to pneumococcal surface adhesin A in the diagnosis of pneumococcal pneumonia among adults in Kenya.

scientific article published on 17 June 2002

Variant surface antigen-specific IgG and protection against clinical consequences of pregnancy-associated Plasmodium falciparum malaria

scientific article published in January 2004

Variation in the ICAM1 gene is not associated with severe malaria phenotypes

scientific article published on 5 June 2008

Variation in use of erythrocyte invasion pathways by Plasmodium falciparum mediates evasion of human inhibitory antibodies ⬇️

scientific article

Vector-related case-control study of severe malaria in Kilifi District, Kenya

scientific article published on May 1999

Video assessment of simple respiratory signs.

scientific article published on December 1996

Volume status in severe malaria: no evidence provided for the degree of filling of the intravascular compartment

scientific article

WHO, the Global Fund, and medical malpractice in malaria treatment

scientific article published in April 2004

What you see is not what you get: implications of the brevity of antibody responses to malaria antigens and transmission heterogeneity in longitudinal studies of malaria immunity

scientific article published on 28 October 2009

Whole-genome scans provide evidence of adaptive evolution in Malawian Plasmodium falciparum isolates

scientific article

Why do some African children develop severe malaria?

scientific article published in October 1991

Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?

scientific article

Wild isolates of Plasmodium falciparum show extensive polymorphism in T cell epitopes of the circumsporozoite protein

scientific article published on 01 December 1989

Wind direction and proximity to larval sites determines malaria risk in Kilifi District in Kenya

scientific article published on 14 February 2012

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