List of works - Mathias Christmann

(-)-Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels

scientific article

A General One-Pot Synthesis of 2H-Indazoles Using an Organophosphorus-Silane System.

scientific article published on 12 April 2018

A formal, one-pot β-chlorination of primary alcohols and its utilization in the transformation of terpene feedstock and the synthesis of a C2-symmetrical terminal bis-epoxide.

scientific article published on 28 January 2014

Access to skipped polyene macrolides through ring-closing metathesis: total synthesis of the RNA polymerase inhibitor ripostatin B

scientific article published on 15 February 2012

Amine-catalyzed cyclizations of tethered alpha,beta-unsaturated carbonyl compounds

scientific article published on 01 January 2008

Asymmetric Synthesis of Carbocyclic Propellanes.

scientific article published on 26 April 2017

Bioinspired synthesis of pentacyclic onocerane triterpenoids

scientific article published on 16 October 2017

Chlorinated isomers of nonylphenol differ in estrogenic and androgenic activity

scientific article published on 01 January 2011

Crossed intramolecular Rauhut-Currier-type reactions via dienamine activation

scientific article published on 01 September 2009

Dienamine-Induced Divinylcyclopropane-Cycloheptadiene Rearrangements

scientific article published on 12 March 2019

Efficient synthesis and resolution of pyrrolizidines

scientific article published on 01 January 2007

Enabling strategies for step efficient syntheses

scientific article published on 01 October 2018

Enantiogroup-differentiating biocatalytic reductions of prochiral Cs -symmetrical dicarbonyl compounds to meso compounds.

scientific article published on 27 April 2015

Enantioselective tandem reactions at elevated temperatures: one-pot hydroformylation/SN1 alkylation

scientific article published on 28 June 2012

Enantioselective α- and γ-alkylation of α,β-unsaturated aldehydes using dienamine activation

scientific article published on 07 December 2010

Five-Step Synthesis of Yaequinolones J1 and J2

scientific article published on 07 January 2020

Identification of an (-)-Englerin A analogue which antagonizes (-)-Englerin A at TRPC1/4/5 channels. ⬇️

scientific article

In Situ Synthesis and Applications for Polyinterhalides based on BrCl

scientific article published on 06 April 2020

Mechanistic Characterisation of Two Sesquiterpene Cyclases from the Plant Pathogenic Fungus Fusarium fujikuroi

scientific article published on 13 June 2016

Mechanistic Studies on the Organocatalytic α-Chlorination of Aldehydes: The Role and Nature of Off-Cycle Intermediates

scientific article published on 03 August 2018

Multivalent polyglycerol supported imidazolidin-4-one organocatalysts for enantioselective Friedel-Crafts alkylations

scientific article published on 12 May 2015

N,N'-carbonyldiimidazole-mediated cyclization of amino alcohols to substituted azetidines and other N-heterocycles

scientific article published on 01 May 2006

N-Hydroxysuccinimide-Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates

scientific article published on 07 January 2020

Na+ entry through heteromeric TRPC4/C1 channels mediates (-)Englerin A-induced cytotoxicity in synovial sarcoma cells ⬇️

scientific article

New developments in the asymmetric Stetter reaction

scientific article published on 01 April 2005

One-Pot Synthesis of 5-Hydroxy-4H-1,3-thiazin-4-ones: Structure Revision, Synthesis, and NMR Shift Dependence of Thiasporine A.

scientific article published on 10 June 2016

One-pot oxidation/isomerization of Z-allylic alcohols with oxygen as stoichiometric oxidant

scientific article published on 08 October 2012

One-pot reactions accelerate the synthesis of active pharmaceutical ingredients

scientific article published on 04 March 2011

Organophosphorus-mediated N-N bond formation: facile access to 3-amino-2H-indazoles

scientific article

Otto Wallach: Founder of Terpene Chemistry and Nobel Laureate 1910 ⬇️

scientific article published on December 10, 2010

Oxidation of allylic and benzylic alcohols to aldehydes and carboxylic acids

scientific article published on 7 April 2014

Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels ⬇️

scientific article published on 21 March 2017

Probing 2H-Indazoles as Templates for SGK1, Tie2, and SRC Kinase Inhibitors

scientific article published on 31 July 2019

Protein Modification of Lysine with 2-(2-Styrylcyclopropyl)ethanal

scientific article published on 11 December 2019

Rapid access to polyketide scaffolds via vinylogous Mukaiyama aldol reactions

scientific article published on 01 November 2001

Scalable Synthesis of Functionalized Ferrocenyl Azides and Amines Enabled by Flow Chemistry

scientific article published on 15 January 2020

Selective oxidation of aliphatic C-H bonds in the synthesis of complex molecules

scientific article published on 01 January 2008

Semisynthesis of Plant-Derived Englerin A Enabled by Microbe Engineering of Guaia-6,10(14)-diene as Building Block

scientific article published on 03 February 2020

Synthesis and Structure Revision of Dichrocephones A and B.

scientific article

Synthesis of (+)-Darwinolide, a Biofilm-Penetrating Anti-MRSA Agent

scientific article published on 18 December 2018

Synthesis of (+)-Greek Tobacco Lactone via a Diastereoablative Epoxidation and a Selenium-Catalyzed Oxidative Cyclization.

scientific article published on 3 March 2017

Synthesis of (+)-Vitepyrroloid A and (+)-Vitepyrroloid B by Late-Stage Ni-Catalyzed C(sp2)-C(sp3) Cross-Electrophile Coupling

scientific article published on 31 May 2018

Synthesis of Enantioenriched Bromohydrins via Divergent Reactions of Racemic Intermediates from Anchimeric Oxygen Borrowing

scientific article published on 16 August 2018

Synthesis of Highly Enantioenriched Propelladienes and their Application as Ligands in Asymmetric Rh-Catalyzed 1,4-Additions

scientific article published on 14 August 2018

Synthesis of Quinolinone Alkaloids via Aryne Insertions into Unsymmetric Imides in Flow

scientific article published on 27 November 2018

Synthesis of Spongidine A and D and Petrosaspongiolide L Methyl Ester Using Pyridine C-H Functionalization

scientific article published on 26 December 2019

Synthesis of Thelepamide via Catalyst-Controlled 1,4-Addition of Cysteine Derivatives and Structure Revision of Thelepamide.

scientific article published on 10 January 2018

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A ⬇️

article by Sin Ying Cheung et al published 3 July 2018 in Oncotarget

The chemistry and biology of ratjadone

scientific article published on 01 September 2001

The first total synthesis of +-ratjadone

scientific article published on 01 March 2001

Total Synthesis of (+)-Ratjadone

scientific article published on 01 December 2000

Total synthesis and absolute configuration of the guaiane sesquiterpene englerin A.

scientific article published in January 2009

Total synthesis and biological evaluation of (-)-englerin A and B: synthesis of analogues with improved activity profile

scientific article published on 29 March 2011

Total synthesis of phorboxazole A via de novo oxazole formation: convergent total synthesis

scientific article published on 29 December 2010

Total synthesis of phorboxazole A via de novo oxazole formation: strategy and component assembly

scientific article published on 29 December 2010

Total synthesis: towards artificial terpene cyclases.

scientific article published on July 2010

Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis

scientific article published in Nature Communications

Transforming terpene feedstock into polyketide architecture

scientific article published on 10 September 2010

Transforming terpene-derived aldehydes into 1,2-epoxides via asymmetric α-chlorination: subsequent epoxide opening with carbon nucleophiles

scientific article published on 10 October 2011

β-Lactones through catalytic asymmetric heterodimerization of ketenes

scientific article published on 24 July 2012

List of works by Mathias Christmann

(-)-Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels

A General One-Pot Synthesis of 2H-Indazoles Using an Organophosphorus-Silane System.

A formal, one-pot β-chlorination of primary alcohols and its utilization in the transformation of terpene feedstock and the synthesis of a C2-symmetrical terminal bis-epoxide.

Access to skipped polyene macrolides through ring-closing metathesis: total synthesis of the RNA polymerase inhibitor ripostatin B

Amine-catalyzed cyclizations of tethered alpha,beta-unsaturated carbonyl compounds

Asymmetric Synthesis of Carbocyclic Propellanes.

Bioinspired synthesis of pentacyclic onocerane triterpenoids

Chlorinated isomers of nonylphenol differ in estrogenic and androgenic activity

Crossed intramolecular Rauhut-Currier-type reactions via dienamine activation

Dienamine-Induced Divinylcyclopropane-Cycloheptadiene Rearrangements

Efficient synthesis and resolution of pyrrolizidines

Enabling strategies for step efficient syntheses

Enantiogroup-differentiating biocatalytic reductions of prochiral Cs -symmetrical dicarbonyl compounds to meso compounds.

Enantioselective tandem reactions at elevated temperatures: one-pot hydroformylation/SN1 alkylation

Enantioselective α- and γ-alkylation of α,β-unsaturated aldehydes using dienamine activation

Five-Step Synthesis of Yaequinolones J1 and J2

Identification of an (-)-Englerin A analogue which antagonizes (-)-Englerin A at TRPC1/4/5 channels. ⬇️

In Situ Synthesis and Applications for Polyinterhalides based on BrCl

Mechanistic Characterisation of Two Sesquiterpene Cyclases from the Plant Pathogenic Fungus Fusarium fujikuroi

Mechanistic Studies on the Organocatalytic α-Chlorination of Aldehydes: The Role and Nature of Off-Cycle Intermediates

Multivalent polyglycerol supported imidazolidin-4-one organocatalysts for enantioselective Friedel-Crafts alkylations

N,N'-carbonyldiimidazole-mediated cyclization of amino alcohols to substituted azetidines and other N-heterocycles

N-Hydroxysuccinimide-Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates

Na+ entry through heteromeric TRPC4/C1 channels mediates (-)Englerin A-induced cytotoxicity in synovial sarcoma cells ⬇️

New developments in the asymmetric Stetter reaction

One-Pot Synthesis of 5-Hydroxy-4H-1,3-thiazin-4-ones: Structure Revision, Synthesis, and NMR Shift Dependence of Thiasporine A.

One-pot oxidation/isomerization of Z-allylic alcohols with oxygen as stoichiometric oxidant

One-pot reactions accelerate the synthesis of active pharmaceutical ingredients

Organophosphorus-mediated N-N bond formation: facile access to 3-amino-2H-indazoles

Otto Wallach: Founder of Terpene Chemistry and Nobel Laureate 1910 ⬇️

Oxidation of allylic and benzylic alcohols to aldehydes and carboxylic acids

Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels ⬇️

Probing 2H-Indazoles as Templates for SGK1, Tie2, and SRC Kinase Inhibitors

Protein Modification of Lysine with 2-(2-Styrylcyclopropyl)ethanal

Rapid access to polyketide scaffolds via vinylogous Mukaiyama aldol reactions

Scalable Synthesis of Functionalized Ferrocenyl Azides and Amines Enabled by Flow Chemistry

Selective oxidation of aliphatic C-H bonds in the synthesis of complex molecules

Semisynthesis of Plant-Derived Englerin A Enabled by Microbe Engineering of Guaia-6,10(14)-diene as Building Block

Synthesis and Structure Revision of Dichrocephones A and B.

Synthesis of (+)-Darwinolide, a Biofilm-Penetrating Anti-MRSA Agent

Synthesis of (+)-Greek Tobacco Lactone via a Diastereoablative Epoxidation and a Selenium-Catalyzed Oxidative Cyclization.

Synthesis of (+)-Vitepyrroloid A and (+)-Vitepyrroloid B by Late-Stage Ni-Catalyzed C(sp2)-C(sp3) Cross-Electrophile Coupling

Synthesis of Enantioenriched Bromohydrins via Divergent Reactions of Racemic Intermediates from Anchimeric Oxygen Borrowing

Synthesis of Highly Enantioenriched Propelladienes and their Application as Ligands in Asymmetric Rh-Catalyzed 1,4-Additions

Synthesis of Quinolinone Alkaloids via Aryne Insertions into Unsymmetric Imides in Flow

Synthesis of Spongidine A and D and Petrosaspongiolide L Methyl Ester Using Pyridine C-H Functionalization

Synthesis of Thelepamide via Catalyst-Controlled 1,4-Addition of Cysteine Derivatives and Structure Revision of Thelepamide.

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A ⬇️

The chemistry and biology of ratjadone

The first total synthesis of +-ratjadone

Total Synthesis of (+)-Ratjadone

Total synthesis and absolute configuration of the guaiane sesquiterpene englerin A.

Total synthesis and biological evaluation of (-)-englerin A and B: synthesis of analogues with improved activity profile

Total synthesis of phorboxazole A via de novo oxazole formation: convergent total synthesis

Total synthesis of phorboxazole A via de novo oxazole formation: strategy and component assembly

Total synthesis: towards artificial terpene cyclases.

Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis

Transforming terpene feedstock into polyketide architecture

Transforming terpene-derived aldehydes into 1,2-epoxides via asymmetric α-chlorination: subsequent epoxide opening with carbon nucleophiles

β-Lactones through catalytic asymmetric heterodimerization of ketenes