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List of works by Dónal O'Carroll

220-plex microRNA expression profile of a single cell

scientific article

A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming

scientific article

A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway

scientific article

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

scientific article published on 07 January 2019

A transit-amplifying population underpins the efficient regenerative capacity of the testis.

scientific article

Argonaute2 mediates compensatory expansion of the pancreatic β cell

scientific article

Blimp1 and the emergence of the germ line during development in the mouse

scientific article

Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland

scientific journal article

Blimp1 is a critical determinant of the germ cell lineage in mice

scientific article

Blimp1 regulates the transition of neonatal to adult intestinal epithelium

scientific article

Cerebellar neurodegeneration in the absence of microRNAs

scientific article

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

scientific article

Defective germline reprogramming rewires the spermatogonial transcriptome

Deficiency in the nuclear long noncoding RNA causes myogenic defects and heart remodeling in mice

scientific article published on 03 September 2018

Dicer is selectively important for the earliest stages of erythroid development.

scientific article

Dicer-dependent microRNA pathway safeguards regulatory T cell function

scientific article

Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein

scientific article

Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate

scientific article published on 3 February 2014

Essential role for Argonaute2 protein in mouse oogenesis

scientific article published on 10 August 2009

Expression of Piwi protein MIWI2 defines a distinct population of multiciliated cells.

scientific article published on 18 September 2017

Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.

scientific article published on 15 February 2017

G9a co-suppresses LINE1 elements in spermatogonia.

scientific article published on 11 September 2014

General principals of miRNA biogenesis and regulation in the brain.

scientific article

Genome-wide identification of targets and function of individual MicroRNAs in mouse embryonic stem cells

scientific article

Germline recruitment in mice: a genetic program for epigenetic reprogramming.

scientific article published in January 2006

Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance

scientific article published on 7 December 2015

Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin.

scientific article published on 10 December 2001

Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression

scientific article

JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells

scientific article published on 01 February 2021

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

scientific article (publication date: 2 November 2001)

Maternal microRNAs are essential for mouse zygotic development

scientific journal article

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

scientific article (publication date: March 2001)

MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.

scientific article

MicroRNA degradation by a conserved target RNA regulates animal behavior.

scientific article published on 26 February 2018

MicroRNA-128 governs neuronal excitability and motor behavior in mice

scientific article published on December 2013

MicroRNAs are tightly associated with RNA-induced gene silencing complexes in vivo

scientific article

Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs

scientific journal article

Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis

scientific journal article

NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells

scientific article published on 24 June 2021

Oligoasthenoteratozoospermia and infertility in mice deficient for miR-34b/c and miR-449 loci

scientific article

PIWI-interacting RNAs: small RNAs with big functions

scientific article published on 01 February 2019

Quantitative functions of Argonaute proteins in mammalian development.

scientific article published in April 2012

Regulation of chromatin structure by site-specific histone H3 methyltransferases

scientific article

Reversible block of mouse neural stem cell differentiation in the absence of dicer and microRNAs.

scientific article

SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation

scientific article published on 16 July 2020

TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing

scientific article published on 27 July 2020

Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia

scientific article published on 25 April 2019

Terminal uridylyltransferases target RNA viruses as part of the innate immune system

scientific article published on 13 August 2018

The RNA m6A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence

scientific article published on 30 August 2017

The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses.

scientific article

The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements

scientific journal article

The miR-144/451 locus is required for erythroid homeostasis

scientific article

The miR-144/451eGFP allele, a novel tool for resolving the erythroid potential of hematopoietic precursors.

scientific article published on 25 July 2011

The murine polycomb-group genes Ezh1 and Ezh2 map close to Hox gene clusters on mouse chromosomes 11 and 6.

scientific article

The polycomb-group gene Ezh2 is required for early mouse development

scientific article (publication date: July 2001)

Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution

scientific article

mRNA 3' uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome

scientific article

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