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List of works by Olivier Toussaint

Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study

scientific article

Age-related cellular copper dynamics in the fungal ageing model Podospora anserina and in ageing human fibroblasts

scientific article

Anti-inflammatory effects of dietary phenolic compounds in an in vitro model of inflamed human intestinal epithelium ⬇️

scientific article published on December 5, 2010

Approach of evolutionary theories of ageing, stress, senescence-like phenotypes, calorie restriction and hormesis from the view point of far-from-equilibrium thermodynamics

scientific article

Artefactual effects of oxygen on cell culture models of cellular senescence and stem cell biology

scientific article published on February 2011

Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK-AGE Project

scientific article published on 19 July 2017

Biological models for phytochemical research: from cell to human organism

scientific article published on May 2008

Can TiC nanoparticles produce toxicity in oral administration to rats?

scientific article published on 12 May 2014

Copper(II) oxide nanoparticles penetrate into HepG2 cells, exert cytotoxicity via oxidative stress and induce pro-inflammatory response

scientific article published in November 2012

Deoxynivalenol affects in vitro intestinal epithelial cell barrier integrity through inhibition of protein synthesis

scientific article published in April 2010

Differentially abundant transcripts in PBMC of hospitalized geriatric patients with hip fracture compared to healthy aged controls

scientific article published on 11 November 2010

Dimethyl sulfoxide (DMSO) attenuates the inflammatory response in the in vitro intestinal Caco-2 cell model

scientific article published on 22 August 2011

Down-regulation and decreased activity of cyclin-dependent kinase 2 in H2O2-induced premature senescence

scientific article published in February 2003

Eco-, geno- and human toxicology of bio-active nanoparticles for biomedical applications

scientific article

From the Hayflick mosaic to the mosaics of ageing. Role of stress-induced premature senescence in human ageing

scientific article

Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase

scientific article

Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging).

scientific article published on April 2007

HAGR: the Human Ageing Genomic Resources

scientific article

Heme oxygenase-1 and interleukin-11 are overexpressed in stress-induced premature senescence of human WI-38 fibroblasts induced by tert-butylhydroperoxide and ethanol

scientific article published on 13 February 2007

High throughput 'omics' approaches to assess the effects of phytochemicals in human health studies

scientific article published on May 2008

How bioinformatics can help reverse engineer human aging

scientific article published on April 2004

Identification of 30 protein species involved in replicative senescence and stress-induced premature senescence

scientific article published on November 2002

Identification of p38MAPK-dependent genes with changed transcript abundance in H2O2-induced premature senescence of IMR-90 hTERT human fibroblasts

scientific article published on 7 November 2006

Identification of p53-dependent genes potentially involved in UVB-mediated premature senescence of human skin fibroblasts using siRNA technology

scientific article published on 9 November 2007

Impact of ageing on proteasome structure and function in human lymphocytes

scientific article published in May 2003

Knocking down p53 with siRNA does not affect the overexpression of p21WAF-1 after exposure of IMR-90 hTERT fibroblasts to a sublethal concentration of H2O2 leading to premature senescence

scientific article published on April 2007

MARK-AGE biomarkers of ageing

scientific article

MARK-AGE population: From the human model to new insights

scientific article

No increase in senescence-associated beta-galactosidase activity in Werner syndrome fibroblasts after exposure to H2O2.

scientific article published in June 2004

Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide

scientific article published on January 2002

Physio-pathological parameters affect the activation of inflammatory pathways by deoxynivalenol in Caco-2 cells

scientific article published on 13 July 2010

Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35-74 Years) General Population: A Cross-Sectional Study in Six European Countries

scientific article

Prematurely senescent ARPE-19 cells display features of age-related macular degeneration

scientific article published on 28 January 2008

Pro-inflammatory effects of different MWCNTs dispersions in p16(INK4A)-deficient telomerase-expressing human keratinocytes but not in human SV-40 immortalized sebocytes

scientific article published on 28 February 2011

Protection against Tetanus and Diphtheria in Europe: The impact of age, gender and country of origin based on data from the MARK-AGE Study

scientific article published on 7 October 2017

Proteomic profiling of human keratinocytes undergoing UVB-induced alternative differentiation reveals TRIpartite Motif Protein 29 as a survival factor

scientific article (publication date: 3 May 2010)

Proteomics in experimental gerontology

scientific article

Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo

scientific article published in January 2009

Quality control data of physiological and immunological biomarkers measured in serum and plasma

scientific article

Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway.

scientific article published on 25 January 2005

Repeated exposures to UVB induce differentiation rather than senescence of human keratinocytes lacking p16(INK-4A).

scientific article

Retrovirally mediated overexpression of peroxiredoxin VI increases the survival of WI-38 human diploid fibroblasts exposed to cytotoxic doses of tert-butylhydroperoxide and UVB.

scientific article

Role of Prion protein in premature senescence of human fibroblasts

scientific article published on 08 August 2017

Role of p38MAPK and oxidative stress in copper-induced senescence ⬇️

scientific article published on April 12, 2013

Role of the PLA2-independent peroxiredoxin VI activity in the survival of immortalized fibroblasts exposed to cytotoxic oxidative stress

scientific article (publication date: 16 January 2004)

Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts

scientific article

Serum IL-6 and IGF-1 improve clinical prediction of functional decline after hospitalization in older patients

scientific article published on 6 May 2010

Serum N-glycan profile shift during human ageing

scientific article

Signal transduction in H2O2-induced senescence-like phenotype in human diploid fibroblasts

scientific article published in November 2002

Stress-induced premature senescence and replicative senescence are different phenotypes, proteomic evidence

scientific article

Stress-induced premature senescence and tissue ageing

scientific article

Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts

scientific article published on July 2002

Stress-induced premature senescence: from biomarkers to likeliness of in vivo occurrence

scientific article

Telomeres and telomerase: a modern fountain of youth?

scientific article

The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

scientific article

The evolution of mammalian aging

scientific article

Transcriptomic biomarkers of the response of hospitalized geriatric patients admitted with heart failure. Comparison to hospitalized geriatric patients with infectious diseases or hip fracture

scientific article

Transcriptomic biomarkers of the response of hospitalized geriatric patients with infectious diseases

scientific article published on 17 August 2010

Transient increased extracellular release of H2O2 during establishment of UVB-induced premature senescence

scientific article published on November 2007

UV, stress and aging

scientific article published on July 2012

UVB-induced premature senescence of human diploid skin fibroblasts

scientific article (publication date: November 2002)

Zinc-induced Metallothionein in centenarian offspring from a large European population: the MARK-AGE Project

scientific article

p38MAPK in the Senescence of Human and Murine Fibroblasts ⬇️

scientific article published on January 1, 2010

p53 and ATF-2 partly mediate the overexpression of COX-2 in H(2)O (2)-induced premature senescence of human fibroblasts

scientific article

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